Ginsenoside Rb1 preconditioning enhances eNOS expression and attenuates myocardial ischemia/reperfusion injury in diabetic rats

Journal of Biomedicine and Biotechnology

Volumn 2011, Issue , 2011, Pages

  Xia, Rui ^a   Zhao, Bo ^a   Wu, Yang ^a   Hou, Jia Bao ^a   Zhang, Li ^a   Xu, Jin Jin ^a   Xia, Zhong Yuan ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE KINASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GINSENOSIDE RB 1; LACTATE DEHYDROGENASE; N(G) NITROARGININE METHYL ESTER; GINSENOSIDE; NITRIC OXIDE; NOS3 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIABETES MELLITUS; ENDOTHELIAL DYSFUNCTION; EXPERIMENTAL RAT; HEART INFARCTION SIZE; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HISTOPATHOLOGY; ISCHEMIC PRECONDITIONING; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; ANIMAL; APOPTOSIS; BIOSYNTHESIS; BLOOD; DRUG EFFECT; ENZYMOLOGY; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION; HEART INFARCTION PREVENTION; METABOLISM; METHODOLOGY; PATHOLOGY; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; APOPTOSIS; CREATINE KINASE; DIABETES MELLITUS, EXPERIMENTAL; GENE EXPRESSION; GINSENOSIDES; ISCHEMIC PRECONDITIONING, MYOCARDIAL; L-LACTATE DEHYDROGENASE; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84855183918     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2011/767930     Document Type: Article

References (39)

1. Tsang A., Hausenloy D. J., Mocanu M. M., Carr R. D., Yellon D. M., Preconditioning the diabetic heart: the importance of Akt phosphorylation Diabetes 2005 54 8 2360 2364 (Pubitemid 41134263)
2. Cerghizan A., Bala C., Nita C., Hancu N., Practical aspect of the control of cardiovascular risk in type 2 diabetes mellitus and the metabolic syndrome Experimental and Clinical Cardiology 2007 12 2 83 86 (Pubitemid 47049460)
3. Donahoe S. M., Stewart G. C., McCabe C. H., Mohanavelu S., Murphy S. A., Cannon C. P., Antman E. M., Diabetes and mortality following acute coronary syndromes Journal of the American Medical Association 2007 298 7 765 775 (Pubitemid 47263159)
4. Zhang Y., Wei L., Sun D., Cao F., Gao H., Zhao L., Du J., Li Y., Wang H., Tanshinone IIA pretreatment protects myocardium against ischaemia/reperfusion injury through the phosphatidylinositol 3-kinase/Akt-dependent pathway in diabetic rats Diabetes, Obesity and Metabolism 2010 12 4 316 322
5. Wu Y., Xia Z. Y., Dou J., Zhang L., Xu J. J., Zhao B., Lei S., Liu H. M., Protective effect of ginsenoside Rb1 against myocardial ischemia/reperfusion injury in streptozotocin-induced diabetic rats Molecular Biology Reports 2010 1 9
6. Bulhak A. A., Sjquist P. O., Xu C. B., Edvinsson L., Pernow J., Protection against myocardial ischaemia/reperfusion injury by PPAR- activation is related to production of nitric oxide and endothelin-1 Basic Research in Cardiology 2006 101 3 244 252
7. Gourine A. V., Bulhak A. A., Gonon A. T., Pernow J., Sjquist P. O., Cardioprotective effect induced by brief exposure to nitric oxide before myocardial ischemia-reperfusion in vivo Nitric Oxide 2002 7 3 210 216 (Pubitemid 35346225)
8. Andelov E., Bartekov M., Pancza D., Styk J., Ravingerov T., The role of NO in ischemia/reperfusion injury in isolated rat heart General Physiology and Biophysics 2005 24 4 411 426 (Pubitemid 43264066)
9. Endemann D. H., Schiffrin E. L., Nitric oxide, oxidative excess, and vascular complications of diabetes mellitus Current Hypertension Reports 2004 6 2 85 89 (Pubitemid 39359547)
10. Naruse K., Rask-Madsen C., Takahara N., Ha S. W., Suzuma K., Way K. J., Jacobs J. R. C., Clermont A. C., Ueki K., Ohshiro Y., Zhang J., Goldfine A. B., King G. L., Activation of vascular protein kinase C-beta; inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance Diabetes 2006 55 3 691 698 (Pubitemid 43343225)
11. Vicent D., Ilany J., Kondo T., Naruse K., Fisher S. J., Kisanuki Y. Y., Bursell S., Yanagisawa M., King G. L., Kahn C. R., The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance Journal of Clinical Investigation 2003 111 9 1373 1380 (Pubitemid 36554708)
12. Sumeray M. S., Rees D. D., Yellon D. M., Infarct size and nitric oxide synthase in murine myocardium Journal of Molecular and Cellular Cardiology 2000 32 1 35 42 (Pubitemid 30064302)
13. Jugdutt B. I., Nitric oxide and cardioprotection during ischemia-reperfusion Heart Failure Reviews 2002 7 4 391 405 (Pubitemid 35396471)
14. Wang Z., Li M., Wu W. K., Tan H. M., Geng D. F., Ginsenoside Rb1 preconditioning protects against myocardial infarction after regional ischemia and reperfusion by activation of phosphatidylinositol-3- kinase signal transduction Cardiovascular Drugs and Therapy 2008 22 6 443 452
15. Guan L., Li W., Liu Z., Effect of ginsenoside-Rb1 on cardiomyocyte apoptosis after ischemia and reperfusion in rats Journal of Huazhong University of Science and TechnologyMedical Science 2002 22 3 212 215 (Pubitemid 41559837)
16. Thirunavukkarasu M., Penumathsa S. V., Koneru S., Juhasz B., Zhan L., Otani H., Bagchi D., Das D. K., Maulik N., Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of nitric oxide, thioredoxin, and heme oxygenase Free Radical Biology and Medicine 2007 43 5 720 729 (Pubitemid 47102122)
17. Maslov L. N., Lishmanov Y. B., Oeltgen P. R., Barzakh E. I., Krylatov A. V., Govindaswami M., Brown S. A., Activation of peripheral 2 opioid receptors increases cardiac tolerance to ischemia/reperfusion injury. Involvement of protein kinase C, NO-synthase, KATP channels and the autonomic nervous system Life Sciences 2009 84 19-20 657 663
18. Xia Z. Y., Gao J., Ancharaz A. K., Liu K. X., Xia Z., Luo T., Ischaemic post-conditioning protects lung from ischaemia-reperfusion injury by up-regulation of haeme oxygenase-1 Injury 2010 41 5 510 516
19. Liu P., Xiang J. Z., Zhao L., Yang L., Hu B. R., Fu Q., Effect of 2-adrenergic agonist clenbuterol on ischemia/reperfusion injury in isolated rat hearts and cardiomyocyte apoptosis induced by hydrogen peroxide Acta Pharmacologica Sinica 2008 29 6 661 669 (Pubitemid 351799468)
20. Nishikawa T., Edelstein D., Du X. L., Yamagishi S. I., Matsumura T., Kaneda Y., Yorek M. A., Beebe D., Oates P. J., Hammes H. P., Glardino I., Brownlee M., Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage Nature 2000 404 6779 787 790 (Pubitemid 30212409)
21. Beckman J. A., Goldfine A. B., Gordon M. B., Creager M. A., Ascorbate restores endothelium-dependent vasodilation impaired by acute hyperglycemia in humans Circulation 2001 103 12 1618 1623 (Pubitemid 32246607)
22. Tan K. C. B., Chow W. S., Ai V. H. G., Metz C., Bucala R., Lam K. S. L., Advanced glycation end products and endothelial dysfunction in type 2 diabetes Diabetes Care 2002 25 6 1055 1059 (Pubitemid 41110493)
23. Szab C., Zanchi A., Komjti K., Pacher P., Krolewski A. S., Quist W. C., LoGerfo F. W., Horton E. S., Veves A., Poly(ADP-ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity Circulation 2002 106 21 2680 2686 (Pubitemid 35364922)
24. Cosentino F., Eto M., De Paolis P., Van der Loo B. V., Bachschmid M., Ullrich V., Kouroedov A., Gatti C. D., Joch H., Volpe M., Lscher T. F., High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species Circulation 2003 107 7 1017 1023 (Pubitemid 36258726)
25. Kajstura J., Fiordaliso F., Andreoli A. M., Li B., Chimenti S., Medow M. S., Limana F., Nadal-Ginard B., Leri A., Anversa P., IGF-1 0verexpression inhibits the development of diabetic cardiomyopathy and angiotensin II-mediated oxidative stress Diabetes 2001 50 6 1414 1424 (Pubitemid 32500175)
26. Marty J. C., Bendhadra S., Amoureux S., Guilland J. C., Vergely C., Rochette L., Girard C., Oxidative stress is exacerbated in diabetic patients during cardiopulmonary bypass Annales de Cardiologie et d'Angeiologie 2008 57 3 155 160
27. Jones S. P., Greer J. J. M., van Haperen R., Duncker D. J., De Crom R., Lefer D. J., Endothelial nitric oxide synthase overexpression attenuates congestive heart failure in mice Proceedings of the National Academy of Sciences of the United States of America 2003 100 8 4891 4896 (Pubitemid 36457824)
28. Herman A. G., Moncada S., Therapeutic potential of nitric oxide donors in the prevention and treatment of atherosclerosis European Heart Journal 2005 26 19 1945 1955 (Pubitemid 41435726)
29. Sharp B. R., Jones S. P., Rimmer D. M., Lefer D. J., Differential response to myocardial reperfusion injury in eNOS-deficient mice American Journal of PhysiologyHeart and Circulatory Physiology 2002 282 6 H2422 H2426
30. Brunner F., Maier R., Andrew P., Wlkart G., Zechner R., Mayer B., Attenuation of myocardial ischemia/reperfusion injury in mice with myocyte-specific overexpression of endothelial nitric oxide synthase Cardiovascular Research 2003 57 1 55 62 (Pubitemid 36009436)
31. Calvert J. W., Lefer D. J., Myocardial protection by nitrite Cardiovascular Research 2009 83 2 195 203
32. Yang X. P., Liu Y. H., Shesely E. G., Bulagannawar M., Liu F., Carretero O. A., Endothelial nitric oxide gene knockout mice: cardiac phenotypes and the effect of angiotensin-converting enzyme inhibitor on myocardial ischemia/reperfusion injury Hypertension 1999 34 1 24 30 (Pubitemid 29325714)
33. L J. P., Ma Z. C., Yang J., Huang J., Wang S. R., Wang S. Q., Ginsenoside Rg1-induced alterations in gene expression in TNF- stimulated endothelial cells Chinese Medical Journal 2004 117 6 871 876 (Pubitemid 38961682)
34. Zhou W., Chai H., Lin P. H., Lumsden A. B., Yao Q., Chen C., Ginsenoside Rb1 blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries Journal of Vascular Surgery 2005 41 5 861 868 (Pubitemid 40693810)
35. Fu W., Conklin B. S., Lin P. H., Lumsden A. B., Yao Q., Chen C., Red wine prevents homocysteine-induced endothelial dysfunction in porcine coronary arteries Journal of Surgical Research 2003 115 1 82 91 (Pubitemid 37323952)
36. Spencer T. A., Chai H., Fu W., Ramaswami G., Cox M. W., Conklin B. S., Lin P. H., Lumsden A. B., Yao Q., Chen C., Estrogen blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries Journal of Surgical Research 2004 118 1 83 90 (Pubitemid 38490520)
37. Xia Z. Y., Liu X. Y., Zhan L. Y., He Y. H., Luo T., Xia Z., Ginsenosides compound (shen-fu) attenuates gastrointestinal injury and inhibits inflammatory response after cardiopulmonary bypass in patients with congenital heart disease Journal of Thoracic and Cardiovascular Surgery 2005 130 2 258 264 (Pubitemid 41074150)
38. Attele A. S., Zhou Y. P., Xie J. T., Wu J. A., Zhang L., Dey L., Pugh W., Rue P. A., Polonsky K. S., Yuan C. S., Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component Diabetes 2002 51 6 1851 1858 (Pubitemid 34564298)
39. Yu J., Eto M., Akishita M., Kaneko A., Ouchi Y., Okabe T., Signaling pathway of nitric oxide production induced by ginsenoside Rb1 in human aortic endothelial cells: a possible involvement of androgen receptor Biochemical and Biophysical Research Communications 2007 353 3 764 769 (Pubitemid 46048736)