-
1
-
-
1842684453
-
Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs
-
DOI 10.1016/j.biopha.2004.02.001, PII S0753332204000319
-
Gursoy R. N., Benita S. - Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs. - Biomed. Pharmacother., 58, 173-182, 2004. (Pubitemid 38479922)
-
(2004)
Biomedicine and Pharmacotherapy
, vol.58
, Issue.3
, pp. 173-182
-
-
Gursoy, R.N.1
Benita, S.2
-
2
-
-
79960035007
-
Solubility advantage of amorphous drugs and pharmaceutical cocrystals
-
Babu N. J., Nangia A. - Solubility advantage of amorphous drugs and pharmaceutical cocrystals. - Cryst. Growth Des., 11, 2662-2679, 2011.
-
(2011)
Cryst. Growth Des.
, vol.11
, pp. 2662-2679
-
-
Babu, N.J.1
Nangia, A.2
-
3
-
-
67649268606
-
Oral lipid-based formulations: Enhancing the bioavailability of poorly water-soluble drugs
-
New York
-
Hauss D. H. Ed. - Oral lipid-based formulations: Enhancing the bioavailability of poorly water-soluble drugs. - Informa Healthcare, New York, 2007.
-
(2007)
Informa Healthcare
-
-
Hauss, D.H.1
-
4
-
-
84871711798
-
Lipid-based formulations for oral delivery of lipophilic drugs
-
Kuentz M. - Lipid-based formulations for oral delivery of lipophilic drugs. - Drug Discovery Today: Technologies, 9, e97-e104, 2012.
-
(2012)
Drug Discovery Today: Technologies
, vol.9
-
-
Kuentz, M.1
-
5
-
-
68349160715
-
Lipid - An emerging platform for oral delivery of drugs with poor bioavailability
-
Chakraborty S., Shukla D., Mishra B., Singh S. - Lipid - an emerging platform for oral delivery of drugs with poor bioavailability. - Eur. J. Pharm. Biopharm., 73, 1-70, 2009.
-
(2009)
Eur. J. Pharm. Biopharm.
, vol.73
, pp. 1-70
-
-
Chakraborty, S.1
Shukla, D.2
Mishra, B.3
Singh, S.4
-
6
-
-
33646813333
-
Bioavailability of seocalcitol. II: Development and characterisation of self-microemulsifying drug delivery systems (SMEDDS) for oral administration containing medium and long chain triglycerides
-
DOI 10.1016/j.ejps.2006.02.005, PII S0928098706000480
-
Grove M., Müllertz A., Nielsen J. L., Pedersen G. P. - Bioavailability of seocalcitol. II. Development and characterisation of self-microemulsifying drug delivery systems (SMEDDS) for oral administration containing medium and long chain triglycerides. - Eur. J. Pharm. Sci., 28, 233-242, 2006. (Pubitemid 43766097)
-
(2006)
European Journal of Pharmaceutical Sciences
, vol.28
, Issue.3
, pp. 233-242
-
-
Grove, M.1
Mullertz, A.2
Nielsen, J.L.3
Pedersen, G.P.4
-
7
-
-
78049499869
-
New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs
-
Müllertz A., Ogbonna A., Ren S., Rades T. - New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs. - J. Pharm. Pharmacol., 62, 1622-1636, 2010.
-
(2010)
J. Pharm. Pharmacol.
, vol.62
, pp. 1622-1636
-
-
Müllertz, A.1
Ogbonna, A.2
Ren, S.3
Rades, T.4
-
9
-
-
34547864243
-
Drug delivery strategies for poorly water-soluble drugs
-
DOI 10.1517/17425247.4.4.403
-
Fahr A., Liu X. - Drug delivery strategies for poorly water-soluble drugs. - Expert Opin. Drug Deliv., 4, 403-416, 2007. (Pubitemid 47249138)
-
(2007)
Expert Opinion on Drug Delivery
, vol.4
, Issue.4
, pp. 403-416
-
-
Fahr, A.1
Liu, X.2
-
10
-
-
34548049221
-
Oral lipid-based formulations
-
Hauss D. H. - Oral lipid-based formulations. - Adv. Drug Delivery. Rev., 59, 667-676, 2007.
-
(2007)
Adv. Drug Delivery. Rev.
, vol.59
, pp. 667-676
-
-
Hauss, D.H.1
-
11
-
-
33847394968
-
Lipids and lipid-based formulations: Optimizing the oral delivery of lipophilic drugs
-
DOI 10.1038/nrd2197, PII NRD2197
-
Porter C. J. H., Trevaskis N. L., Charman W. N. - Lipids and lipidbased formulations: Optimizing the oral delivery of lipophilic drugs. - Nat. Rev. Drug Discovery, 6, 231-248, 2007. (Pubitemid 46344627)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.3
, pp. 231-248
-
-
Porter, C.J.H.1
Trevaskis, N.L.2
Charman, W.N.3
-
12
-
-
79955629340
-
Nano-emulsions and micro-emulsions: Clarifications of the critical differences
-
Anton N., Vandamme T. - Nano-emulsions and micro-emulsions: Clarifications of the critical differences. - Pharm. Res., 28, 978-985, 2011.
-
(2011)
Pharm. Res.
, vol.28
, pp. 978-985
-
-
Anton, N.1
Vandamme, T.2
-
13
-
-
84874398327
-
Proposal of stability categories for nano-dispersions obtained from pharmaceutical self-emulsifying formulations
-
online first
-
Niederquell A., Kuentz M. - Proposal of stability categories for nano-dispersions obtained from pharmaceutical self-emulsifying formulations. - Int. J. Pharm., online first, http://dx.doi.org/10.1016/j.ijpharm.2013.02.005, 2013.
-
(2013)
Int. J. Pharm.
-
-
Niederquell, A.1
Kuentz, M.2
-
14
-
-
0031913402
-
Dissolution testing as a prognostic tool for oral drug absorption: Immediate release dosage forms
-
DOI 10.1023/A:1011984216775
-
Dressman J. B., Amidon G. L., Reppas C., Shah V. P. - Dissolution testing as a prognostic tool for oral drug absorption: Immediate release dosage forms. - Pharm. Res., 15, 11-22, 1998. (Pubitemid 28080861)
-
(1998)
Pharmaceutical Research
, vol.15
, Issue.1
, pp. 11-22
-
-
Dressman, J.B.1
Amidon, G.L.2
Reppas, C.3
Shah, V.P.4
-
15
-
-
58549106999
-
Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products
-
Fatouros D. G., Walrand I., Bergenstahl B., Müllertz A. - Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products. - Pharm. Res., 26, 361-374, 2008.
-
(2008)
Pharm. Res.
, vol.26
, pp. 361-374
-
-
Fatouros, D.G.1
Walrand, I.2
Bergenstahl, B.3
Müllertz, A.4
-
16
-
-
0027250231
-
Secretion and contribution to lipolysis of gastric and pancreatic lipases during a test meal in humans
-
Carriere F., Barrowman J. A., Verger R., Laugier R. - Secretion and contribution to lipolysis of gastric and pancreatic lipases during atest meal in humans. - Gastroenterology, 105, 876-888, 1993. (Pubitemid 23249500)
-
(1993)
Gastroenterology
, vol.105
, Issue.3
, pp. 876-888
-
-
Carriere, F.1
Barrowman, J.A.2
Verger, R.3
Laugier, R.4
-
17
-
-
75849147141
-
The influence of emulsion structure and stability on lipid digestion
-
Golding M., Wooster T. J. - The influence of emulsion structure and stability on lipid digestion. - Curr. Opin. Colloid Interface Sci., 15, 90-101, 2010.
-
(2010)
Curr. Opin. Colloid Interface Sci.
, vol.15
, pp. 90-101
-
-
Golding, M.1
Wooster, T.J.2
-
18
-
-
0001473068
-
Influence of bile salt, pH, and time on the action of pancreatic lipase: Physiological implications
-
Borgstróm B. - Influence of bile salt, pH, and time on the action of pancreatic lipase: Physiological implications. - J. Lipid Res., 5, 522-531, 1964.
-
(1964)
J. Lipid Res.
, vol.5
, pp. 522-531
-
-
Borgstróm, B.1
-
19
-
-
0018731882
-
Pancreatic colipase: Chemistry and physiology
-
Borgstróm B., Erlanson-Albertsson C., Wieloch T. - Pancreatic colipase: Chemistry and physiology. - J. Lipid Res., 20, 805-816, 1979. (Pubitemid 10245347)
-
(1979)
Journal of Lipid Research
, vol.20
, Issue.7
, pp. 805-816
-
-
Borgstrom, B.1
Erlanson-Albertsson, C.2
Wieloch, T.3
-
20
-
-
0020689194
-
Lipid digestion and absorption
-
Carey M. C., Small D. M., Bliss C. M. - Lipid digestion and absorption. - Annu. Rev. Physiol., 45, 651-677, 1983.
-
(1983)
Annu. Rev. Physiol.
, vol.45
, pp. 651-677
-
-
Carey, M.C.1
Small, D.M.2
Bliss, C.M.3
-
21
-
-
0018765360
-
Watching fat digestion
-
Patton J. S., Carey M. C. - Watching fat digestion. - Science, 204, 145-148, 1979.
-
(1979)
Science
, vol.204
, pp. 145-148
-
-
Patton, J.S.1
Carey, M.C.2
-
22
-
-
0032805749
-
Digestion and absorption of 2 fat emulsions with different droplet sizes in the human digestive tract
-
Armand M., Pasquier B., André M., Borel P., Senft M., Peyrot J., Salducci J., Portugal H., Jaussan V., Lairon D. - Digestion and absorption of 2 fat emulsions with different droplet sizes in the human digestive tract. - Am. J. Clin. Nutr., 70, 1096-1106, 1999.
-
(1999)
Am. J. Clin. Nutr.
, vol.70
, pp. 1096-1106
-
-
Armand, M.1
Pasquier, B.2
André, M.3
Borel, P.4
Senft, M.5
Peyrot, J.6
Salducci, J.7
Portugal, H.8
Jaussan, V.9
Lairon, D.10
-
23
-
-
0031750861
-
Evaluation of various dissolution media for predicting In vivo performance of class I and II drugs
-
DOI 10.1023/A:1011910801212
-
Galia E., Nicolaides E., Hórter D., Lóbenberg R., Reppas C., Dressman J. B. - Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs. - Pharm. Res., 15, 698-705, 1998. (Pubitemid 28275645)
-
(1998)
Pharmaceutical Research
, vol.15
, Issue.5
, pp. 698-705
-
-
Galia, E.1
Nicolaides, E.2
Horter, D.3
Lobenberg, R.4
Reppas, C.5
Dressman, J.B.6
-
24
-
-
44749087279
-
Dissolution media simulating conditions in the proximal human gastrointestinal tract: An update
-
Jantratid E., Janssen N., Reppas C., Dressman J. D. - Dissolution media simulating conditions in the proximal human gastrointestinal tract: An update. - Pharm. Res., 25, 1663-1676, 2008.
-
(2008)
Pharm. Res.
, vol.25
, pp. 1663-1676
-
-
Jantratid, E.1
Janssen, N.2
Reppas, C.3
Dressman, J.D.4
-
25
-
-
5644294406
-
Solubilisation of poorly water-soluble drugs during in vitro lipolysis of medium- and long-chain triacylglycerols
-
DOI 10.1016/j.ejps.2004.08.003, PII S0928098704002003
-
Christensen J., Schultz K., Mollgard B., Kristensen H. G., Müllertz A. - Solubilisation of poorly water-soluble drugs during in vitro lipolysis of medium-and long-chain triacylglycerols. - Eur. J. Pharm. Sci., 23, 287-296, 2004. (Pubitemid 39369884)
-
(2004)
European Journal of Pharmaceutical Sciences
, vol.23
, Issue.3
, pp. 287-296
-
-
Christensen, J.O.1
Schultz, K.2
Mollgaard, B.3
Kristensen, H.G.4
Mullertz, A.5
-
26
-
-
1242292226
-
Drug solubilization behavior during in vitro digestion of simple triglyceride lipid solution formulations
-
DOI 10.1023/B:PHAM.0000016282.77887.1f
-
Kaukonen A. M., Boyd B. J., Porter C. J. H., Charman W. N. - Drug solubilization behavior during in w'irodigestion of simple triglyceride lipid solution formulations. - Pharm. Res., 21, 245-253, 2004. (Pubitemid 38221969)
-
(2004)
Pharmaceutical Research
, vol.21
, Issue.2
, pp. 245-253
-
-
Kaukonen, A.M.1
Boyd, B.J.2
Porter, C.J.H.3
Charman, W.N.4
-
27
-
-
78649653098
-
Characterising the behaviour of poorly water soluble drugs in the intestine: Application of biorelevant media for solubility, dissolution and transport studies
-
Kleberg K., Jacobsen J., Müllertz A. - Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies. - J. Pharm. Pharmacol., 62, 1656-1668, 2010.
-
(2010)
J. Pharm. Pharmacol.
, vol.62
, pp. 1656-1668
-
-
Kleberg, K.1
Jacobsen, J.2
Müllertz, A.3
-
28
-
-
0033818432
-
Effect of short-, medium-, and long-chain fatty acid-based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of mass balance in lymphcannulated and non-cannulated rats
-
Caliph S. M., Charman W. N., Porter C. J. H. - Effect of short-, medium-, and long-chain fatty acid-based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of mass balance in lymphcannulated and non-cannulated rats. - J. Pharm. Sci., 89, 1073-1084, 2000.
-
(2000)
J. Pharm. Sci.
, vol.89
, pp. 1073-1084
-
-
Caliph, S.M.1
Charman, W.N.2
Porter, C.J.H.3
-
29
-
-
0034854134
-
Comparison of the lymphatic transport of halofantrine administered in disperse systems containing three different unsaturated fatty acids
-
DOI 10.1023/A:1013037927882
-
Holm R., Müllertz A., Pedersen G. P., Kristensen H. G. - Comparison of the lymphatic transport of halofantrine administered in disperse systems containing three different unsaturated fatty acids. - Pharm. Res., 18, 1299-1304, 2001. (Pubitemid 32846323)
-
(2001)
Pharmaceutical Research
, vol.18
, Issue.9
, pp. 1299-1304
-
-
Holm, R.1
Mulertz, A.2
Pedersen, G.P.3
Kristensen, H.G.4
-
30
-
-
0035007337
-
Formulation and physiological and biopharmaceutical issues in the development of oral lipid-based drug delivery systems
-
DOI 10.1081/DDC-100103726
-
Wasan K. M. - Formulation and physiological and biopharmaceutical issues in the development of oral lipid-based drug delivery systems. - Drug Dev. Ind. Pharm., 27, 267-276, 2001. (Pubitemid 32531593)
-
(2001)
Drug Development and Industrial Pharmacy
, vol.27
, Issue.4
, pp. 267-276
-
-
Wasan, K.M.1
-
31
-
-
78649964349
-
Targeted drug delivery to lymphocytes: A route to site-specific immunomodulation?
-
Trevaskis N. L., Charman W. N., Porter C. J. H. - Targeted drug delivery to lymphocytes: a route to site-specific immunomodulation? - Mol. Pharm., 7, 2297-2309, 2010.
-
(2010)
Mol. Pharm.
, vol.7
, pp. 2297-2309
-
-
Trevaskis, N.L.1
Charman, W.N.2
Porter, C.J.H.3
-
32
-
-
4744367567
-
Potential mechanisms by which Peceol increases the gastrointestinal absorption of Amphotericin B
-
DOI 10.1081/DDC-120039793
-
Risovic V., Sachs-Barrable C., Boyd M., Wasan K. M. - Potential mechanisms by which Peceol increases the gastrointestinal absorption of amphotericin B. - Drug Dev. Ind. Pharm., 30, 767-774, 2004. (Pubitemid 39311017)
-
(2004)
Drug Development and Industrial Pharmacy
, vol.30
, Issue.7
, pp. 767-774
-
-
Risovic, V.1
Sachs-Barrable, K.2
Boyd, M.3
Wasan, K.M.4
-
33
-
-
76749131979
-
Impactof emulsionbased drug delivery systems on intestinal permeability and drug release kinetics
-
Buyukozturk F., Benneyan J. C., Carrier R. L. - Impactof emulsionbased drug delivery systems on intestinal permeability and drug release kinetics. - J. Controlled Release, 142, 22-30, 2010.
-
(2010)
J. Controlled Release
, vol.142
, pp. 22-30
-
-
Buyukozturk, F.1
Benneyan, J.C.2
Carrier, R.L.3
-
34
-
-
34848853277
-
Low dose lipid formulations: Effects on gastric emptying and biliary secretion
-
DOI 10.1007/s11095-007-9363-8
-
Kossena G., Charman W. N., Wilson C., O'Mahony B., Lindsay B., Hempenstall J., Davison C., Crowley P., Porter C. - Low dose lipid formulations: Effects on gastric emptying and biliary secretion. - Pharm. Res., 24, 2084-2096, 2007. (Pubitemid 47493578)
-
(2007)
Pharmaceutical Research
, vol.24
, Issue.11
, pp. 2084-2096
-
-
Kossena, G.A.1
Charman, W.N.2
Wilson, C.G.3
O'Mahony, B.4
Lindsay, B.5
Hempenstall, J.M.6
Davison, C.L.7
Crowley, P.J.8
Porter, C.J.H.9
-
35
-
-
57149136074
-
Lipid-based formulations for danazol containing a digestible surfactant, Labrafil M2125CS: In vivo bioavailability and dynamic in vitro lipolysis
-
Larsen A., Holm R., Pedersen M., Müllertz A. - Lipid-based formulations for danazol containing a digestible surfactant, Labrafil M2125CS: In vivo bioavailability and dynamic in vitro lipolysis. - Pharm. Res., 25, 2769-2777, 2008.
-
(2008)
Pharm. Res.
, vol.25
, pp. 2769-2777
-
-
Larsen, A.1
Holm, R.2
Pedersen, M.3
Müllertz, A.4
-
36
-
-
0342617694
-
Lipid-based vehicles for the oral delivery of poorly water soluble drugs
-
Humberstone A. J., Charman W. N. - Lipid-based vehicles for the oral delivery of poorly water soluble drugs. - Adv. Drug Delivery. Rev., 25, 103-128, 1997.
-
(1997)
Adv. Drug Delivery. Rev.
, vol.25
, pp. 103-128
-
-
Humberstone, A.J.1
Charman, W.N.2
-
37
-
-
0347022226
-
Intestinal absorption of penclomedine from lipid vehicles in the conscious rat: Contribution of emulsification versus digestibility
-
DOI 10.1016/j.ijpharm.2003.10.036
-
de Smidt P. C., Campanero M. A., Troconiz I. F. - Intestinal absorption of penclomedine from lipid vehicles in the conscious rat: contribution of émulsification versus digestibility. - Int. J. Pharm., 270, 109-118, 2004. (Pubitemid 38077092)
-
(2004)
International Journal of Pharmaceutics
, vol.270
, Issue.1-2
, pp. 109-118
-
-
De Smidt, P.C.1
Campanero, M.A.2
Troconiz, I.F.3
-
38
-
-
43249122851
-
Bioavailability of probucol from lipid and surfactant based formulations in minipigs: Influence of droplet size and dietary state
-
Nielsen F. S., Petersen K. B., Müllertz A. - Bioavailability of probucol from lipid and surfactant based formulations in minipigs: Influence of droplet size and dietary state. - Eur. J. Pharm. Biopharm., 69, 553-562, 2008.
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.69
, pp. 553-562
-
-
Nielsen, F.S.1
Petersen, K.B.2
Müllertz, A.3
-
39
-
-
39149126301
-
Biopharmaceutical challenges associated with drugs with low aqueous solubility-The potential impact of lipid-based formulations
-
O'Driscoll C. M., Griffin B. T. - Biopharmaceutical challenges associated with drugs with low aqueous solubility-The potential impact of lipid-based formulations. - Adv. Drug Delivery. Rev., 60, 617-624, 2008.
-
(2008)
Adv. Drug Delivery. Rev.
, vol.60
, pp. 617-624
-
-
O'Driscoll, C.M.1
Griffin, B.T.2
-
40
-
-
34247536339
-
Morphological observations on a lipid-based drug delivery system during in vitro digestion
-
DOI 10.1016/j.ejps.2007.02.009, PII S0928098707000486
-
Fatouros D. G., Bergenstahl B., Müllertz A. - Morphological observations on a lipid-based drug delivery system during in vitro digestion. - Eur. J. Pharm. Sci., 31, 85-94, 2007. (Pubitemid 46660577)
-
(2007)
European Journal of Pharmaceutical Sciences
, vol.31
, Issue.2
, pp. 85-94
-
-
Fatouros, D.G.1
Bergenstahl, B.2
Mullertz, A.3
-
41
-
-
0025239461
-
Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 1. Phase behavior and aggregation states of model lipid systems patterned after aqueous duodenal contents of healthy adult human beings
-
Staggers J. E., Hernell O., Stafford R. J., Carey M. C. - Physicalchemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 1. Phase behavior and aggregation states of model lipid systems patterned after aqueous duodenal contents of healthy adult human beings. - Biochemistry (Mosc.), 29, 2028-2040, 1990. (Pubitemid 20085428)
-
(1990)
Biochemistry
, vol.29
, Issue.8
, pp. 2028-2040
-
-
Staggers, J.E.1
Hernell, O.2
Stafford, R.J.3
Carey, M.C.4
-
42
-
-
0025264030
-
Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings
-
Hernell O., Staggers J. E., Carey M. C. - Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings. - Biochemistry (Mosc.), 29, 2041-2056, 1990. (Pubitemid 20085429)
-
(1990)
Biochemistry
, vol.29
, Issue.8
, pp. 2041-2056
-
-
Hernell, O.1
Staggers, J.E.2
Carey, M.C.3
-
43
-
-
0842289328
-
Probing drug solubilization patterns in the gastrointestinal tract after administration of lipid-based delivery systems: A phase diagram approach
-
DOI 10.1002/jps.10554
-
Kossena G. A., Charman W. N., Boyd B. J., Dunstan D. E., Porter C. J. H. - Probing drug solubilization patterns in the gastrointestinal tract after administration of lipid-based delivery systems: A phase diagram approach. - J. Pharm. Sci., 92, 332-348, 2004. (Pubitemid 38174256)
-
(2004)
Journal of Pharmaceutical Sciences
, vol.93
, Issue.2
, pp. 332-348
-
-
Kossena, G.A.1
Charman, W.N.2
Boyd, B.J.3
Dunstan, D.E.4
Porter, C.J.H.5
-
44
-
-
16444375502
-
Influence of the intermediate digestion phases of common formulation lipids on the absorption of a poorly water-soluble drug
-
DOI 10.1002/jps.20260
-
Kossena G. A., Charman W. N., Boyd B. J., Porter C. J. H. - Influence of the intermediate digestion phases of common formulation lipids on the absorption of a poorly water-soluble drug. - J. Pharm. Sci., 94, 481-492, 2005. (Pubitemid 40476514)
-
(2005)
Journal of Pharmaceutical Sciences
, vol.94
, Issue.3
, pp. 481-492
-
-
Kossena, G.A.1
Charman, W.N.2
Boyd, B.J.3
Porter, C.J.H.4
-
45
-
-
84864323714
-
Influence of lipid composition and drug load on the in vitro performance of self-nanoemulsifying drug delivery systems
-
Thomas N., Müllertz A., Graf A., Rades T. - Influence of lipid composition and drug load on the in vitro performance of self-nanoemulsifying drug delivery systems. - J. Pharm. Sci., 101, 1721-1731, 2012.
-
(2012)
J. Pharm. Sci.
, vol.101
, pp. 1721-1731
-
-
Thomas, N.1
Müllertz, A.2
Graf, A.3
Rades, T.4
-
46
-
-
84864051006
-
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: Method parameterization and comparison of in vitro digestion profiles across a range of representative formulations
-
Williams H. D., Sassene P., Kleberg K., Bakala-N'Goma J.-C., Calderone M., Jannin V., Igonin A., Partheil A., Marchaud D., Jule E., Vertommen J., Maio M., Blundell R., Benameur H., Carrière F., Müllertz A., Porter C. J. H., Pouton C. W. - Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: Method parameterization and comparison of in vitro digestion profiles across a range of representative formulations. - J. Pharm. Sci., 101, 3360-3380, 2012.
-
(2012)
J. Pharm. Sci.
, vol.101
, pp. 3360-3380
-
-
Williams, H.D.1
Sassene, P.2
Kleberg, K.3
Bakala-N'Goma, J.-C.4
Calderone, M.5
Jannin, V.6
Igonin, A.7
Partheil, A.8
Marchaud, D.9
Jule, E.10
Vertommen, J.11
Maio, M.12
Blundell, R.13
Benameur, H.14
Carrière, F.15
Müllertz, A.16
Porter, C.J.H.17
Pouton, C.W.18
-
47
-
-
1242337285
-
Solubilizing excipients in oral and injectable formulations
-
DOI 10.1023/B:PHAM.0000016235.32639.23
-
Strickley R. G. - Solubilizing excipients in oral and injectable formulations. - Pharm. Res., 21, 201-230, 2004. (Pubitemid 38221966)
-
(2004)
Pharmaceutical Research
, vol.21
, Issue.2
, pp. 201-230
-
-
Strickley, R.G.1
-
48
-
-
0033805858
-
Lipid formulations for oral administration of drugs: Non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems
-
Pouton C. W. - Lipid formulations for oral administration of drugs: Non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems. - Eur. J. Pharm. Sci., 11, S93-S98, 2000.
-
(2000)
Eur. J. Pharm. Sci.
, vol.11
-
-
Pouton, C.W.1
-
49
-
-
84877259367
-
Strategies to address low drug solubility in discovery and development
-
Williams H. D., Trevaskis N. L., Charman S. A., Shanker R. M., Charman W. N., Pouton C. W., Porter C. J. H. - Strategies to address low drug solubility in discovery and development. - Pharmacol. Rev., 65, 315-499, 2013.
-
(2013)
Pharmacol. Rev.
, vol.65
, pp. 315-499
-
-
Williams, H.D.1
Trevaskis, N.L.2
Charman, S.A.3
Shanker, R.M.4
Charman, W.N.5
Pouton, C.W.6
Porter, C.J.H.7
-
50
-
-
0028948839
-
Atheoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability
-
Amidon G., Lennernaes H., Shah V. P., Crison J. R. - Atheoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability. - Pharm. Res., 12, 413-420, 1995.
-
(1995)
Pharm. Res.
, vol.12
, pp. 413-420
-
-
Amidon, G.1
Lennernaes, H.2
Shah, V.P.3
Crison, J.R.4
-
51
-
-
57449093598
-
Solid form screening - A review
-
Aaltonen J., Alleso M., Mirza S., Koradia V., Gordon K. C., Rantanen J. - Solid form screening - A review. - Eur. J. Pharm. Biopharm., 71, 23-37, 2009.
-
(2009)
Eur. J. Pharm. Biopharm.
, vol.71
, pp. 23-37
-
-
Aaltonen, J.1
Alleso, M.2
Mirza, S.3
Koradia, V.4
Gordon, K.C.5
Rantanen, J.6
-
52
-
-
34447646495
-
Developing early formulations: Practice and perspective
-
DOI 10.1016/j.ijpharm.2007.05.049, PII S0378517307004553
-
Li P., Zhao L. - Developing early formulations: Practice and perspective. - Int. J. Pharm., 341, 1-19, 2007. (Pubitemid 47088122)
-
(2007)
International Journal of Pharmaceutics
, vol.341
, Issue.1-2
, pp. 1-19
-
-
Li, P.1
Zhao, L.2
-
53
-
-
0034762181
-
A conscious dog model for assessing the absorption, enterocyte-based metabolism, and intestinal lymphatic transport of halofantrine
-
DOI 10.1002/jps.1110
-
Khoo S.-M., Edwards G. A., Porter C. J. H., Charman W. N. - A conscious dog model for assessing the absorption, enterocytebased metabolism, and intestinal lymphatic transport of halofantrine. - J. Pharm. Sci., 90, 1599-1607, 2001. (Pubitemid 32979754)
-
(2001)
Journal of Pharmaceutical Sciences
, vol.90
, Issue.10
, pp. 1599-1607
-
-
Khoo, S.-M.1
Edwards, G.A.2
Porter, C.J.H.3
Charman, W.N.4
-
54
-
-
79959707350
-
Improving the oral absorption of poorly soluble drugs using SEDDS and S-SEDDS formulations
-
Yihong Q., Yisheng C., Zhang G. Z., Liu L., Porter W. R. Eds., Academic Press, San Diego
-
Morozowich W., Gao P. - Improving the oral absorption of poorly soluble drugs using SEDDS and S-SEDDS formulations. - In: Yihong Q., Yisheng C., Zhang G. Z., Liu L., Porter W. R. (Eds.), Developing Solid Oral Dosage Forms, Academic Press, San Diego, 2009, p. 443-468.
-
(2009)
Developing Solid Oral Dosage Forms
, pp. 443-468
-
-
Morozowich, W.1
Gao, P.2
-
55
-
-
34247472175
-
Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds
-
DOI 10.1002/jps.20673
-
Nielsen F. S., Gibault E., Ljusberg-WahrenH., Arleth L., Pedersen J. S., Müllertz A. - Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds. - J. Pharm. Sci., 96, 876-892, 2007. (Pubitemid 46657875)
-
(2007)
Journal of Pharmaceutical Sciences
, vol.96
, Issue.4
, pp. 876-892
-
-
Nielsen, F.S.1
Gibault, E.2
Ljusberg-Wahren, H.3
Arleth, L.4
Pedersen, J.S.5
Mullertz, A.6
-
56
-
-
0035902686
-
The effect of α-tocopherol on the in vitro solubilisation of lipophilic drugs
-
DOI 10.1016/S0378-5173(01)00701-3, PII S0378517301007013
-
Nielsen P. B., Müllertz A., Norling T., Kristensen H. G. - The effect of [alpha]-tocopherol on the in vitro solubilisation of lipophilic drugs. - Int. J. Pharm., 222, 217-224, 2001. (Pubitemid 32568365)
-
(2001)
International Journal of Pharmaceutics
, vol.222
, Issue.2
, pp. 217-224
-
-
Nielsen, P.B.1
Mullertz, A.2
Norling, T.3
Kristensen, H.G.4
-
57
-
-
84871578131
-
SNEDDS containing poorly water soluble cinnarizine; development and in vitro characterization of dispersion, digestion and solubilization
-
Larsen A. T., Ogbonna A., Abu-Rhmaileh R., Abrahamsson B., Østergaard J., Müllertz A. - SNEDDS containing poorly water soluble cinnarizine; development and in vitro characterization of dispersion, digestion and solubilization. - Pharmaceutics, 4, 641-665, 2012.
-
(2012)
Pharmaceutics
, vol.4
, pp. 641-665
-
-
Larsen, A.T.1
Ogbonna, A.2
Abu-Rhmaileh, R.3
Abrahamsson, B.4
Østergaard, J.5
Müllertz, A.6
-
58
-
-
34848863347
-
Clinical studies with oral lipid based formulations of poorly soluble compounds
-
Fatouros D. G., Karpf D. M., Nielsen F. S., Müllertz A. - Clinical studies with oral lipid based formulations of poorly soluble compounds. - Ther. Clin. Risk Manag., 3, 591-604, 2007. (Pubitemid 47496964)
-
(2007)
Therapeutics and Clinical Risk Management
, vol.3
, Issue.4
, pp. 591-604
-
-
Fatouros, D.G.1
Karpf, D.M.2
Nielsen, F.S.3
Mullertz, A.4
-
59
-
-
82255196159
-
Comparison of high-resolution ultrasonic resonator technology and Raman spectroscopy as novel process analytical tools for drug quantification in self-emulsifying drug delivery systems
-
Stillhart C., Kuentz M. - Comparison of high-resolution ultrasonic resonator technology and Raman spectroscopy as novel process analytical tools for drug quantification in self-emulsifying drug delivery systems. - J. Pharm. Biomed. Anal., 59, 29-37, 2012.
-
(2012)
J. Pharm. Biomed. Anal.
, vol.59
, pp. 29-37
-
-
Stillhart, C.1
Kuentz, M.2
-
60
-
-
0028329964
-
Improved dose linearity of cyclosporine pharmacokinetics from a microemulsion formulation
-
DOI 10.1023/A:1018923912135
-
Mueller E. A., Kovarik J. M., van Bree J. B., Tetzloff W., Grevel J., Kutz K. - Improved dose linearity of cyclosporine pharmacokinetics from a microemulsion formulation. - Pharm. Res., 11, 301-304, 1994. (Pubitemid 24076228)
-
(1994)
Pharmaceutical Research
, vol.11
, Issue.2
, pp. 301-304
-
-
Mueller, E.A.1
Kovarik, J.M.2
Van Bree, J.B.3
Tetzloff, W.4
Grevel, J.5
Kutz, K.6
-
61
-
-
84871441882
-
Oral bioavailability of cinnarizine in dogs: Relation to SNEDDS droplet size, drug solubility and in vitro precipitation
-
Larsen A. T., Ohlsson A. G., Polentarutti B., Barker R. A., Phillips A. R., Abu-Rmaileh R., Dickinson P. A., Abrahamsson B., Østergaard J., Müllertz A. - Oral bioavailability of cinnarizine in dogs: Relation to SNEDDS droplet size, drug solubility and in vitro precipitation. - Eur. J. Pharm. Sci., 48, 339-350, 2013.
-
(2013)
Eur. J. Pharm. Sci.
, vol.48
, pp. 339-350
-
-
Larsen, A.T.1
Ohlsson, A.G.2
Polentarutti, B.3
Barker, R.A.4
Phillips, A.R.5
Abu-Rmaileh, R.6
Dickinson, P.A.7
Abrahamsson, B.8
Østergaard, J.9
Müllertz, A.10
-
62
-
-
77955247636
-
Development and oral bioavailability assessment of a supersaturated self-microemulsifying drug delivery system (SMEDDS) of albendazole
-
Mukherjee T., Plakogiannis F. M. - Development and oral bioavailability assessment of a supersaturated self-microemulsifying drug delivery system (SMEDDS) of albendazole. - J. Pharm. Pharmacol., 62, 1112-1120, 2010.
-
(2010)
J. Pharm. Pharmacol.
, vol.62
, pp. 1112-1120
-
-
Mukherjee, T.1
Plakogiannis, F.M.2
-
63
-
-
84861182434
-
Rational formulation development and in vitro assessment of SMEDDS for oral delivery of poorly water soluble drugs
-
Sprunk A., Strachan C. J., Graf A. - Rational formulation development and in vitro assessment of SMEDDS for oral delivery of poorly water soluble drugs. - Eur. J. Pharm. Sci., 46, 508-515, 2012.
-
(2012)
Eur. J. Pharm. Sci.
, vol.46
, pp. 508-515
-
-
Sprunk, A.1
Strachan, C.J.2
Graf, A.3
-
64
-
-
84875878549
-
Optimization of self nanoemulsifying drug delivery system for poorly watersoluble drug using response surface methodology
-
online first, doi: 10.3109/03639045.2012.710634
-
Ren S., Mu H., Alchaer F., Chtatou A., Müllertz A. - Optimization of self nanoemulsifying drug delivery system for poorly watersoluble drug using response surface methodology. - Drug Dev. Ind. Pharm., online first, doi: 10.3109/03639045.2012.710634, 1-8, 2012.
-
(2012)
Drug Dev. Ind. Pharm.
, pp. 1-8
-
-
Ren, S.1
Mu, H.2
Alchaer, F.3
Chtatou, A.4
Müllertz, A.5
-
65
-
-
80052265520
-
Invitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systems
-
Larsen A. T., Sassene P., Müllertz A. - Invitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systems. - Int. J. Pharm., 417, 245-255, 2011.
-
(2011)
Int. J. Pharm.
, vol.417
, pp. 245-255
-
-
Larsen, A.T.1
Sassene, P.2
Müllertz, A.3
-
66
-
-
84869114981
-
Characterising lipid lipolysis and its implication in lipid-based formulation development
-
Thomas N., Holm R., Rades T., Müllertz A. - Characterising lipid lipolysis and its implication in lipid-based formulation development. - AAPS J., 14, 860-871, 2012.
-
(2012)
AAPS J.
, vol.14
, pp. 860-871
-
-
Thomas, N.1
Holm, R.2
Rades, T.3
Müllertz, A.4
-
67
-
-
0035016152
-
Characterisation and quantification of medium chain and long chain triglycerides and their in vitro digestion products, by HPTLC coupled with in situ densitometric analysis
-
DOI 10.1016/S0731-7085(00)00528-8, PII S0731708500005288
-
Sek L., Pouton C. W., Charman W. N. - Characterisation and quantification of medium chain and long chain triglycerides and their in vitro digestion products, by HPTLC coupled with in situ densitometric analysis. - J. Pharm. Biomed. Anal., 25, 651-661, 2001. (Pubitemid 32493922)
-
(2001)
Journal of Pharmaceutical and Biomedical Analysis
, vol.25
, Issue.3-4
, pp. 651-661
-
-
Sek, L.1
Porter, C.J.H.2
Charman, W.N.3
-
68
-
-
84866733513
-
Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis
-
Parmentier J., Thomas N., Müllertz A., Fricker G., Rades T. - Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis. - Int. J. Pharm., 437, 253-263, 2012.
-
(2012)
Int. J. Pharm.
, vol.437
, pp. 253-263
-
-
Parmentier, J.1
Thomas, N.2
Müllertz, A.3
Fricker, G.4
Rades, T.5
-
69
-
-
34548567075
-
Structural development of self nano emulsifying drug delivery systems (SNEDDS) during in vitro lipid digestion monitored by Small-angle X-ray scattering
-
DOI 10.1007/s11095-007-9304-6
-
Fatouros D. G., Deen G. R., Arleth L., Bergenstahl B., Nielsen F. S., Pedersen J. S., Müllertz A. - Structural development of self nano emulsifying drug delivery systems (SNEDDS) during in vitro lipid digestion monitored by small-angle X-ray scattering. - Pharm. Res., 24, 1844-1853, 2007. (Pubitemid 47389238)
-
(2007)
Pharmaceutical Research
, vol.24
, Issue.10
, pp. 1844-1853
-
-
Fatouros, D.G.1
Deen, G.R.2
Arleth, L.3
Bergenstahl, B.4
Nielsen, F.S.5
Pedersen, J.S.6
Mullertz, A.7
-
70
-
-
79960751951
-
Real time evolution of liquid crystalline nanostructure during the digestion of formulation lipids using synchrotron small-angle X-ray scattering
-
Warren D. B., Anby M. U., Hawley A., Boyd B. J. - Real time evolution of liquid crystalline nanostructure during the digestion of formulation lipids using synchrotron small-angle X-ray scattering. - Langmuir, 27, 9528-9534, 2011.
-
(2011)
Langmuir
, vol.27
, pp. 9528-9534
-
-
Warren, D.B.1
Anby, M.U.2
Hawley, A.3
Boyd, B.J.4
-
71
-
-
0034898463
-
A dynamic in vitro lipolysis model. I. Controlling the rate of lipolysis by continuous addition of calcium
-
DOI 10.1016/S0928-0987(01)00169-5, PII S0928098701001695
-
Zangenberg N. H., Müllertz A., Kristensen H. G., Hovgaard L. - A dynamic in vitro lipolysis model. I. Controlling the rate of lipolysis by continuous addition of calcium. - Eur. J. Pharm. Sci., 14, 115-122, 2001. (Pubitemid 32737533)
-
(2001)
European Journal of Pharmaceutical Sciences
, vol.14
, Issue.2
, pp. 115-122
-
-
Zangenberg, N.H.1
Mullertz, A.2
Kristensen, H.G.3
Hovgaard, L.4
-
72
-
-
0034836387
-
A dynamic in vitro lipolysis model. II: Evaluation of the model
-
DOI 10.1016/S0928-0987(01)00182-8, PII S0928098701001828
-
Zangenberg N. H., Müllertz A., Kristensen H. G., Hovgaard L. - A dynamic in vitro lipolysis model. II. Evaluation of the model. - Eur. J. Pharm. Sci., 14, 237-244, 2001. (Pubitemid 32884320)
-
(2001)
European Journal of Pharmaceutical Sciences
, vol.14
, Issue.3
, pp. 237-244
-
-
Zangenberg, N.H.1
Mullertz, A.2
Kristensen, H.G.3
Hovgaard, L.4
-
73
-
-
4344578729
-
Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation
-
DOI 10.1023/B:PHAM.0000036914.22132.cc
-
Porter C. J. H., Kaukonen A. M., Boyd B. J., Edwards G. A., Charman W. N. - Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation. - Pharm. Res., 21, 1405-1412, 2004. (Pubitemid 39149655)
-
(2004)
Pharmaceutical Research
, vol.21
, Issue.8
, pp. 1405-1412
-
-
Porter, C.J.H.1
Kaukonen, A.M.2
Boyd, B.J.3
Edwards, G.A.4
Charman, W.N.5
-
74
-
-
33751014029
-
Formulation of poorly water-soluble drugs for oral administration: Physicochemical and physiological issues and the lipid formulation classification system
-
DOI 10.1016/j.ejps.2006.04.016, PII S0928098706001151
-
Pouton C. W. - Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system. - Eur. J. Pharm. Sci., 29, 278-287, 2006. (Pubitemid 44740131)
-
(2006)
European Journal of Pharmaceutical Sciences
, vol.29
, Issue.3-4 SPEC. ISS.
, pp. 278-287
-
-
Pouton, C.W.1
-
75
-
-
59849110173
-
Characterization and optimization of AMG 517 supersaturatable self-emulsifying drug delivery system (S-SEDDS) for improved oral absorption
-
Gao P., Akrami A., Alvarez F., Hu J., Li L., Ma C., Surapaneni S. - Characterization and optimization of AMG 517 supersaturatable self-emulsifying drug delivery system (S-SEDDS) for improved oral absorption. - J. Pharm. Sci., 98, 516-528, 2009.
-
(2009)
J. Pharm. Sci.
, vol.98
, pp. 516-528
-
-
Gao, P.1
Akrami, A.2
Alvarez, F.3
Hu, J.4
Li, L.5
Ma, C.6
Surapaneni, S.7
-
76
-
-
84871970245
-
Supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) enhance the bioavailability of the poorly water-soluble drug simvastatin in dogs
-
Thomas N., Holm R., Garmer M., Karlsson J. J., Müllertz A., Rades T. - Supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) enhance the bioavailability of the poorly water-soluble drug simvastatin in dogs. - AAPS J., 15, 219-227, 2013.
-
(2013)
AAPS J.
, vol.15
, pp. 219-227
-
-
Thomas, N.1
Holm, R.2
Garmer, M.3
Karlsson, J.J.4
Müllertz, A.5
Rades, T.6
-
77
-
-
84861529172
-
In vitro and in vivo performance of novel supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS)
-
Thomas N., Holm R., Müllertz A., Rades T. - In vitro and in vivo performance of novel supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS). - J. Controlled Release, 160, 25-32, 2012.
-
(2012)
J. Controlled Release
, vol.160
, pp. 25-32
-
-
Thomas, N.1
Holm, R.2
Müllertz, A.3
Rades, T.4
-
78
-
-
78049518013
-
Precipitation of a poorly soluble model drug during in vitro lipolysis: Characterization and dissolution of the precipitate
-
Sassene P. J., Knopp M. M., Hesselkilde J. Z., Koradia V., Larsen A., Rades T., Müllertz A. - Precipitation of a poorly soluble model drug during in vitro lipolysis: Characterization and dissolution of the precipitate. - J. Pharm. Sci., 99, 4982-4991, 2010.
-
(2010)
J. Pharm. Sci.
, vol.99
, pp. 4982-4991
-
-
Sassene, P.J.1
Knopp, M.M.2
Hesselkilde, J.Z.3
Koradia, V.4
Larsen, A.5
Rades, T.6
Müllertz, A.7
-
79
-
-
15244353232
-
Effect of self-microemulsifying drug delivery systems containing Labrasol on tight junctions in Caco-2 cells
-
DOI 10.1016/j.ejps.2005.01.001
-
Sha X., Yan G., Wu Y., Li J., Fang X. - Effect of self-microemulsifying drug delivery systems containing Labrasol on tight junctions in Caco-2 cells. - Eur. J. Pharm. Sci., 24, 477-486, 2005. (Pubitemid 40387261)
-
(2005)
European Journal of Pharmaceutical Sciences
, vol.24
, Issue.5
, pp. 477-486
-
-
Sha, X.1
Yan, G.2
Wu, Y.3
Li, J.4
Fang, X.5
-
80
-
-
0033973754
-
Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: Permeabilities via diffusion, inside- and outside-directed carrier-mediated transport
-
DOI 10.1002/(SICI)1520-6017(200 001)89:1<63::AID-JPS 7>3.0.CO;2-6
-
Hilgendorf C., Spahn-Langguth H., Regärdh C. G., Lipka E., Amidon G. L., Langguth P. - Caco-2 versus caco-2/HT29-MTX co-cultured cell lines: Permeabilities via diffusion, inside-and outside-directed carrier-mediated transport. - J. Pharm. Sci., 89, 63-75, 2000. (Pubitemid 30080155)
-
(2000)
Journal of Pharmaceutical Sciences
, vol.89
, Issue.1
, pp. 63-75
-
-
Hilgendorf, C.1
Spahn-Langguth, H.2
Regardh, C.G.3
Lipka, E.4
Amidon, G.L.5
Langguth, P.6
-
81
-
-
67651015406
-
Characterization of Caco-2 and HT29-MTX cocultures in an in vitro digestion/cell culture model used to predict iron bioavailability
-
Mahler G. J., Shuler M. L., Glahn R. P. - Characterization of Caco-2 and HT29-MTX cocultures in an in vitro digestion/cell culture model used to predict iron bioavailability. - J. Nutr. Biochem., 20, 494-502, 2009.
-
(2009)
J. Nutr. Biochem.
, vol.20
, pp. 494-502
-
-
Mahler, G.J.1
Shuler, M.L.2
Glahn, R.P.3
-
82
-
-
0029836840
-
HT29-MTX/Caco-2 cocultures as an in vitro model for the intestinal epithelium: In vitro-in vivo correlation with permeability data from rats and humans
-
DOI 10.1021/js960110x
-
Walter E., Janich S., Roessler B. J., Hilfinger J. M., Amidon G. L. - HT29-MTX/Caco-2 cocultures as an in vitro model for the intestinal epithelium: In vitro-in vivo correlation with permeability data from rats and humans. - J. Pharm. Sci., 85, 1070-1076, 1996. (Pubitemid 26338920)
-
(1996)
Journal of Pharmaceutical Sciences
, vol.85
, Issue.10
, pp. 1070-1076
-
-
Walter, E.1
Janich, S.2
Roessler, B.J.3
Hilfinger, J.M.4
Amidon, G.L.5
-
83
-
-
0029055473
-
Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals
-
Kararli T. T. - Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals. - Biopharm. Drug Dispos., 16, 351-380, 1995.
-
(1995)
Biopharm. Drug Dispos.
, vol.16
, pp. 351-380
-
-
Kararli, T.T.1
-
84
-
-
68649090154
-
Lipid-based formulations to enhance oral bioavailability of the poorly water-soluble drug anethol trithione: Effects of lipid composition and formulation
-
Han S. F., Yao T. T., Zhang X. X., Gan L., Zhu C., Yu H.-z., Gan Y. - Lipid-based formulations to enhance oral bioavailability of the poorly water-soluble drug anethol trithione: effects of lipid composition and formulation. - Int. J. Pharm., 379, 18-24, 2009.
-
(2009)
Int. J. Pharm.
, vol.379
, pp. 18-24
-
-
Han, S.F.1
Yao, T.T.2
Zhang, X.X.3
Gan, L.4
Zhu, C.5
Yu, H.-Z.6
Gan, Y.7
-
85
-
-
79952282344
-
A novel excipient, 1-perf luorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs
-
Holm R., Jorgensen E. B., Harborg M., Larsen R., Holm P., Müllertz A., Jacobsen J. - A novel excipient, 1-perf luorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs. - Eur. J. Pharm. Sci., 42, 416-422, 2011.
-
(2011)
Eur. J. Pharm. Sci.
, vol.42
, pp. 416-422
-
-
Holm, R.1
Jorgensen, E.B.2
Harborg, M.3
Larsen, R.4
Holm, P.5
Müllertz, A.6
Jacobsen, J.7
-
86
-
-
29244485443
-
A new self-emulsifying formulation of itraconazole with improved dissolution and oral absorption
-
DOI 10.1016/j.jconrel.2005.10.002, PII S0168365905005298
-
Hong J.-Y., Kim J.-K., Song Y.-K., Park J.-S., Kim C.-K. - A new self-emulsifying formulation of itraconazole with improved dissolution and oral absorption. - J. Controlled Release, 110, 332-338, 2006. (Pubitemid 41827486)
-
(2006)
Journal of Controlled Release
, vol.110
, Issue.2
, pp. 332-338
-
-
Hong, J.-Y.1
Kim, J.-K.2
Song, Y.-K.3
Park, J.-S.4
Kim, C.-K.5
-
87
-
-
0041331755
-
Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides
-
DOI 10.1016/S0928-0987(03)00174-X
-
Holm R., Porter C. J. H., Edwards G. A., Müllertz A., Kristensen H. G., Charman W. N. - Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides. - Eur. J. Pharm. Sci., 20, 91-97, 2003. (Pubitemid 37103236)
-
(2003)
European Journal of Pharmaceutical Sciences
, vol.20
, Issue.1
, pp. 91-97
-
-
Holm, R.1
Porter, C.J.H.2
Edwards, G.A.3
Mullertz, A.4
Kristensen, H.G.5
Charman, W.N.6
-
88
-
-
1842609789
-
Development of self-microemulsifying drug delivery systems (SMEDDS) for oral bioavailability enhancement of simvastatin in beagle dogs
-
DOI 10.1016/j.ijpharm.2003.12.028, PII S0378517304000043
-
Kang B. K., Lee J. S., Chon S. K., Jeong S. Y., Yuk S. H., Khang G., Lee H. B., Cho S. H. - Development of self-microemulsifying drug delivery systems (SMEDDS) for oral bioavailability enhancement of simvastatin in beagle dogs. - Int. J. Pharm., 274, 65-73, 2004. (Pubitemid 38457007)
-
(2004)
International Journal of Pharmaceutics
, vol.274
, Issue.1-2
, pp. 65-73
-
-
Kang, B.K.1
Lee, J.S.2
Chon, S.K.3
Jeong, S.Y.4
Yuk, S.H.5
Khang, G.6
Lee, H.B.7
Cho, S.H.8
-
89
-
-
34247137899
-
Bioavailability of seocalcitol. III. Administration of lipid-based formulations to minipigs in the fasted and fed state
-
DOI 10.1016/j.ejps.2007.01.007, PII S0928098707000279
-
Grove M., Pedersen G. P., Nielsen J. L., Müllertz A. - Bioavailability of seocalcitol. (III) Administration of lipid-based formulations to minipigs in the fasted and fed state. - Eur. J. Pharm. Sci., 31, 8-15, 2007. (Pubitemid 46601865)
-
(2007)
European Journal of Pharmaceutical Sciences
, vol.31
, Issue.1
, pp. 8-15
-
-
Grove, M.1
Mullertz, A.2
Pedersen, G.P.3
Nielsen, J.L.4
-
90
-
-
77957220519
-
The utility of the minipig as an animal model in regulatory toxicology
-
Bode G., Clausing P., Gervais F., Loegsted J., Luft J., Nogues V., Sims J. - The utility of the minipig as an animal model in regulatory toxicology. - J. Pharmacol. Toxicol. Methods, 62, 196-220, 2010.
-
(2010)
J. Pharmacol. Toxicol. Methods
, vol.62
, pp. 196-220
-
-
Bode, G.1
Clausing, P.2
Gervais, F.3
Loegsted, J.4
Luft, J.5
Nogues, V.6
Sims, J.7
-
91
-
-
53849134465
-
Current methods for predicting human food effect
-
Lentz K. - Current methods for predicting human food effect. - AAPS J., 10, 282-288, 2008.
-
(2008)
AAPS J.
, vol.10
, pp. 282-288
-
-
Lentz, K.1
-
92
-
-
25444464372
-
Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats - Effect of medium and long chain triglycerides
-
DOI 10.1002/jps.20403
-
Grove M., Pedersen G. P., Nielsen J. L., Müllertz A. - Bioavailability of seocalcitol. (I) Relating solubility in biorelevant media with oral bioavailability in rats - effect of medium and long chain triglycerides. - J. Pharm. Sci., 94, 1830-1838, 2005. (Pubitemid 41360876)
-
(2005)
Journal of Pharmaceutical Sciences
, vol.94
, Issue.8
, pp. 1830-1838
-
-
Grove, M.1
Pedersen, G.P.2
Nielsen, J.L.3
Mullertz, A.4
-
93
-
-
0034004361
-
Gastric pH profiles of beagle dogs and their use as an alternative to human testing
-
DOI 10.1016/S0939-6411(99)00070-3, PII S0939641199000703
-
Akimoto M., Nagahata N., Furuya A., Fukushima K., Higuchi S., Suwa T. - Gastric pH profiles of beagle dogs and their use as an alternative to human testing. - Eur. J. Pharm. Biopharm., 49, 99-102, 2000. (Pubitemid 30126056)
-
(2000)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.49
, Issue.2
, pp. 99-102
-
-
Akimoto, M.1
Nagahata, N.2
Furuya, A.3
Fukushima, K.4
Higuchi, S.5
Suwa, T.6
-
94
-
-
39149091886
-
Evaluation of the impact of surfactant digestion on the bioavailability of danazol after oral administration of lipidic self-emulsifying formulations to dogs
-
DOI 10.1002/jps.21246
-
Cuine J. F., Claire L., McEvoy C. L., Charman W. N., Pouton C. W., Edwards G. A., Benameur H., Porter C. J. H. - Evaluation of the impact of surfactant digestion on the bioavailability of danazol after oral administration of lipidic self-emulsifying formulations to dogs. - J. Pharm. Sci., 97, 995-1012, 2008. (Pubitemid 351293898)
-
(2008)
Journal of Pharmaceutical Sciences
, vol.97
, Issue.2
, pp. 995-1012
-
-
Cuine, J.F.1
Mcevoy, C.L.2
Charman, W.N.3
Pouton, C.W.4
Edwards, G.A.5
Benameur, H.6
Porter, C.J.H.7
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