The utility of the minipig as an animal model in regulatory toxicology

Journal of Pharmacological and Toxicological Methods

Volumn 62, Issue 3, 2010, Pages 196-220

  Bode, Gerd ^a   Clausing, Peter ^a   Gervais, Frederic ^b   Loegsted, Jeanet ^c   Luft, Jörg ^d   Nogues, Vicente ^e   Sims, Jennifer ^f  

^a Department of Non Clinical Drug Safety ^*  (Germany)

^b CIT   (France)

^c Department of Pharmacology   (Denmark)

^d ALTANA PHARMA AG   (Germany)

^e NOVARTIS PHARMA AG   (Switzerland)

^f SYNGENTA CROP PROTECTION AG   (Switzerland)

Author keywords

Methods; Minipig; RETHINK; Toxicology

Indexed keywords

4 NITROPHENOL; BUFURALOL; CHLORZOXAZONE; COUMARIN; CYTOCHROME P450; DEBRISOQUINE; DEXTROMETHORPHAN; DICLOFENAC; DIMETHYLNITROSAMINE; DOFETILIDE; ETHOXYRESORUFIN; LACTOSE; MEPHENYTOIN; MIDAZOLAM; NICOTINE; NIFEDIPINE; PENTOXYRESORUFIN; TESTOSTERONE; TOLBUTAMIDE;

ARTICLE; BIOTECHNOLOGY; CARDIOTOXICITY; DOG; EMBRYOTOXICITY; EXPERIMENTAL MODEL; EYE TOXICITY; FETOTOXICITY; GASTROINTESTINAL TOXICITY; HUMAN; IMMUNOTOXICITY; LIVER TOXICITY; LUNG TOXICITY; MINIPIG; MOUTH DISEASE; NEPHROTOXICITY; NEUROTOXICITY; NONHUMAN; REPRODUCTIVE TOXICITY; SKIN TOXICITY; SPECIES DIFFERENCE; SWINE; TERATOGENESIS; TOXICITY TESTING;

ANIMAL USE ALTERNATIVES; ANIMALS; ANIMALS, LABORATORY; DRUG INDUSTRY; EUROPEAN UNION; FEMALE; GOVERNMENT REGULATION; HUMANS; MALE; MODELS, ANIMAL; RESEARCH DESIGN; SPECIES SPECIFICITY; SWINE; SWINE, MINIATURE; TOXICITY TESTS; XENOBIOTICS;

ANIMALIA; CANIS FAMILIARIS; PRIMATES; RODENTIA; SUIDAE;

EID: 77957220519     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2010.05.009     Document Type: Article

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