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Volumn 2013, Issue , 2013, Pages

Multiple molecular and cellular mechanisms of action of lycopene in cancer inhibition

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; BETA CATENIN; CYCLIN DEPENDENT KINASE; EPIDERMAL GROWTH FACTOR; GENISTEIN; INHIBITOR OF APOPTOSIS PROTEIN; LYCOPENE; MELATONIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; RAF PROTEIN; RAS PROTEIN; SOMATOMEDIN C; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR; VASCULOTROPIN; WNT PROTEIN;

EID: 84881531024     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2013/705121     Document Type: Review
Times cited : (138)

References (124)
  • 1
    • 0027274815 scopus 로고
    • The molecular biology of carcinogenesis
    • Pitot H. C., The molecular biology of carcinogenesis. Cancer 1993 72 supplement 3 962 970 2-s2.0-0027274815 (Pubitemid 23218011)
    • (1993) Cancer , vol.72 , Issue.3 SUPPL. , pp. 962-970
    • Pitot, H.C.1
  • 2
    • 0033179705 scopus 로고    scopus 로고
    • Cancer chemoprevention: Future holds in multiple agents
    • DOI 10.1006/taap.1999.8721
    • Mukhtar H., Ahmad N., Cancer chemoprevention: future holds in multiple agents. Toxicology and Applied Pharmacology 1999 158 3 207 210 2-s2.0-0033179705 10.1006/taap.1999.8721 (Pubitemid 29382938)
    • (1999) Toxicology and Applied Pharmacology , vol.158 , Issue.3 , pp. 207-210
    • Mukhtar, H.1    Ahmad, N.2
  • 3
    • 0037248328 scopus 로고    scopus 로고
    • Cancer prevention - The potential for diet to modulate molecular signalling
    • DOI 10.1016/S1471-4914(02)00002-3, PII S1471491402000023
    • Manson M. M., Cancer prevention-the potential for diet to modulate molecular signalling. Trends in Molecular Medicine 2003 9 1 11 18 2-s2.0-0037248328 10.1016/S1471-4914(02)00002-3 (Pubitemid 36139250)
    • (2003) Trends in Molecular Medicine , vol.9 , Issue.1 , pp. 11-18
    • Manson, M.M.1
  • 5
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh Y.-J., Cancer chemoprevention with dietary phytochemicals. Nature Reviews Cancer 2003 3 10 768 780 2-s2.0-0142166328 (Pubitemid 37328815)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.10 , pp. 768-780
    • Surh, Y.-J.1
  • 6
    • 0030774098 scopus 로고    scopus 로고
    • Cancer prevention through sensible nutrition (Commentary)
    • Challa A., Ahmad N., Mukhtar H., Cancer prevention through sensible nutrition (commentary). International Journal of Oncology 1997 11 6 1387 1392 2-s2.0-0030774098 (Pubitemid 27502099)
    • (1997) International Journal of Oncology , vol.11 , Issue.6 , pp. 1387-1392
    • Challa, A.1    Ahmad, N.2    Mukhtar, H.3
  • 7
    • 27644477094 scopus 로고    scopus 로고
    • Cancer chemoprevention: Scientific promise, clinical uncertainty
    • DOI 10.1038/ncponc0319, PII N0319
    • Sporn M. B., Liby K. T., Cancer chemoprevention: scientific promise, clinical uncertainty. Nature Clinical Practice Oncology 2005 2 10 518 525 2-s2.0-27644477094 10.1038/ncponc0319 (Pubitemid 41553936)
    • (2005) Nature Clinical Practice Oncology , vol.2 , Issue.10 , pp. 518-525
    • Sporn, M.B.1    Liby, K.T.2
  • 8
    • 84865629086 scopus 로고    scopus 로고
    • Lycopene synthesis via tri-cistronic expression of LeGGPS2, LePSY1 and crtI in Escherichia coli
    • Chen J., Pu Z., Xiao Y., Lycopene synthesis via tri-cistronic expression of LeGGPS2, LePSY1 and crtI in Escherichia coli. Sheng Wu Gong Cheng Xue Bao 2012 28 7 823 833
    • (2012) Sheng Wu Gong Cheng Xue Bao , vol.28 , Issue.7 , pp. 823-833
    • Chen, J.1    Pu, Z.2    Xiao, Y.3
  • 9
    • 0029186920 scopus 로고
    • Introduction: The colorful, fascinating world of the carotenoids: Important physiologic modulators
    • 2-s2.0-0029186920
    • Olson J. A., Krinsky N. I., Introduction: the colorful, fascinating world of the carotenoids: important physiologic modulators. The Journal of the Federation of American Societies for Experimental Biology 1995 9 15 1547 1550 2-s2.0-0029186920
    • (1995) The Journal of the Federation of American Societies for Experimental Biology , vol.9 , Issue.15 , pp. 1547-1550
    • Olson, J.A.1    Krinsky, N.I.2
  • 10
    • 0031889382 scopus 로고    scopus 로고
    • Lycopene: Chemistry, biology, and implications for human health and disease
    • Clinton S. K., Lycopene: chemistry, biology, and implications for human health and disease. Nutrition Reviews 1998 56 2, part 1 35 51 2-s2.0-0031889382 (Pubitemid 28132684)
    • (1998) Nutrition Reviews , vol.56 , Issue.2 , pp. 35-51
    • Clinton, S.K.1
  • 12
    • 0027523227 scopus 로고
    • Carotenoid content of fruits and vegetables: An evaluation of analytic data
    • DOI 10.1016/0002-8223(93)91553-3
    • Mangels A. R., Holden J. M., Beecher G. R., Forman M. R., Lanza E., Carotenoid content of fruits and vegetables: an evaluation of analytic data. Journal of the American Dietetic Association 1993 93 3 284 296 2-s2.0-0027523227 10.1016/0002-8223(93)91553-3 (Pubitemid 23070877)
    • (1993) Journal of the American Dietetic Association , vol.93 , Issue.3 , pp. 284-296
    • Mangels, A.R.1    Holden, J.M.2    Beecher, G.R.3    Forman, M.R.4    Lanza, E.5
  • 13
    • 0033577044 scopus 로고    scopus 로고
    • Tomatoes, tomato-based products, lycopene, and cancer: Review of the epidemiologic literature
    • Giovannucci E., Tomatoes, tomato-based products, lycopene, and cancer: review of the epidemiologic literature. Journal of the National Cancer Institute 1999 91 4 317 331 2-s2.0-0033577044 (Pubitemid 29102331)
    • (1999) Journal of the National Cancer Institute , vol.91 , Issue.4 , pp. 317-331
    • Giovannucci, E.1
  • 14
    • 0031964487 scopus 로고    scopus 로고
    • Relationships of serum carotenoids, retinol, α-tocopherol, and selenium with breast cancer risk: Results from a prospective study in Columbia, Missouri (United States)
    • DOI 10.1023/A:1008857521992
    • Dorgan J. F., Sowell A., Swanson C. A., Potischman N., Miller R., Schussler N., Stephenson H. E. Jr., Relationships of serum carotenoids, retinol, α -tocopherol, and selenium with breast cancer risk: results from a prospective study in Columbia, Missouri (United States). Cancer Causes and Control 1998 9 1 89 97 2-s2.0-0031964487 10.1023/A:1008857521992 (Pubitemid 28048664)
    • (1998) Cancer Causes and Control , vol.9 , Issue.1 , pp. 89-97
    • Dorgan, J.F.1    Sowell, A.2    Swanson, C.A.3    Potischman, N.4    Miller, R.5    Schussler, N.6    Stephenson Jr., H.E.7
  • 16
    • 0031797256 scopus 로고    scopus 로고
    • Nitrosative stress
    • DOI 10.1016/S0076-6879(99)00143-3
    • Hausladen A., Stamler J. S., Nitrosative stress. Methods in Enzymology 1999 300 389 395 2-s2.0-0031797256 10.1016/S0076-6879(99)00143-3 (Pubitemid 28500613)
    • (1998) Methods in Enzymology , vol.300 , pp. 389-395
    • Hausladen, A.1    Stamler, J.S.2
  • 17
    • 0025972738 scopus 로고
    • DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems
    • 2-s2.0-0025972738 10.1016/0014-5793(91)80347-6
    • Halliwell B., Aruoma O. I., DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems. Federation of European Biochemical Societies Letter 1991 281 1-2 9 19 2-s2.0-0025972738 10.1016/0014-5793(91)80347-6
    • (1991) Federation of European Biochemical Societies Letter , vol.281 , Issue.1-2 , pp. 9-19
    • Halliwell, B.1    Aruoma, O.I.2
  • 18
    • 0020508747 scopus 로고
    • Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases
    • 2-s2.0-0020508747
    • Ames B. N., Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. Science 1983 221 4617 1256 1264 2-s2.0-0020508747
    • (1983) Science , vol.221 , Issue.4617 , pp. 1256-1264
    • Ames, B.N.1
  • 20
    • 0024464691 scopus 로고
    • Lycopene as the most efficient biological carotenoid singlet oxygen quencher
    • DOI 10.1016/0003-9861(89)90467-0
    • di Mascio P., Kaiser S., Sies H., Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Archives of Biochemistry and Biophysics 1989 274 2 532 538 2-s2.0-0024464691 (Pubitemid 19261144)
    • (1989) Archives of Biochemistry and Biophysics , vol.274 , Issue.2 , pp. 532-538
    • Di Mascio, P.1    Kaiser, S.2    Sies, H.3
  • 21
    • 0032442246 scopus 로고    scopus 로고
    • The antioxidant and biological properties of the carotenoids
    • DOI 10.1111/j.1749-6632.1998.tb09923.x
    • Krinsky N. I., The antioxidant and biological properties of the carotenoids. Annals of the New York Academy of Sciences 1998 854 443 447 2-s2.0-0032442246 10.1111/j.1749-6632.1998.tb09923.x (Pubitemid 29022823)
    • (1998) Annals of the New York Academy of Sciences , vol.854 , pp. 443-447
    • Krinsky, N.I.1
  • 23
    • 0034326266 scopus 로고    scopus 로고
    • Protective effect of lycopene on lipid peroxidation and oxidative DNA damage in cell culture
    • 2-s2.0-0034326266 10.1006/abbi.2000.2035
    • Matos H. R., di Mascio P., Medeiros M. H. G., Protective effect of lycopene on lipid peroxidation and oxidative DNA damage in cell culture. Archives of Biochemistry and Biophysics 2000 383 1 56 59 2-s2.0-0034326266 10.1006/abbi.2000.2035
    • (2000) Archives of Biochemistry and Biophysics , vol.383 , Issue.1 , pp. 56-59
    • Matos, H.R.1    Di Mascio, P.2    Medeiros, M.H.G.3
  • 24
    • 78650478990 scopus 로고    scopus 로고
    • Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: A randomized controlled trial
    • 2-s2.0-78650478990 10.1111/j.1365-2133.2010.10057.x
    • Rizwan M., Rodriguez-Blanco I., Harbottle A., Birch-Machin M. A., Watson R. E. B., Rhodes L. E., Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. British Journal of Dermatology 2011 164 1 154 162 2-s2.0-78650478990 10.1111/j.1365-2133.2010. 10057.x
    • (2011) British Journal of Dermatology , vol.164 , Issue.1 , pp. 154-162
    • Rizwan, M.1    Rodriguez-Blanco, I.2    Harbottle, A.3    Birch-Machin, M.A.4    Watson, R.E.B.5    Rhodes, L.E.6
  • 25
    • 33748058810 scopus 로고    scopus 로고
    • Effect of lycopene and β-carotene on peroxynitrite-mediated cellular modifications
    • DOI 10.1016/j.taap.2006.03.006, PII S0041008X06001049
    • Muzandu K., Ishizuka M., Sakamoto K. Q., Shaban Z., El Bohi K., Kazusaka A., Fujita S., Effect of lycopene and β -carotene on peroxynitrite-mediated cellular modifications. Toxicology and Applied Pharmacology 2006 215 3 330 340 2-s2.0-33748058810 10.1016/j.taap.2006.03.006 (Pubitemid 44301346)
    • (2006) Toxicology and Applied Pharmacology , vol.215 , Issue.3 , pp. 330-340
    • Muzandu, K.1    Ishizuka, M.2    Sakamoto, K.Q.3    Shaban, Z.4    El Bohi, K.5    Kazusaka, A.6    Fujita, S.7
  • 26
    • 33845230150 scopus 로고    scopus 로고
    • Absorption and subcellular localization of lycopene in human prostate cancer cells
    • DOI 10.1158/1535-7163.MCT-06-0373
    • Liu A., Pajkovic N., Pang Y., Zhu D., Calamini B., Mesacar A. L., van Breemen R. B., Absorption and subcellular localization of lycopene in human prostate cancer cells. Molecular Cancer Therapeutics 2006 5 11 2879 2885 2-s2.0-33845230150 10.1158/1535-7163.MCT-06-0373 (Pubitemid 44849015)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.11 , pp. 2879-2885
    • Liu, A.1    Pajkovic, N.2    Pang, Y.3    Zhu, D.4    Calamini, B.5    Mesacar, A.L.6    Van Breemen, R.B.7
  • 28
    • 0036916637 scopus 로고    scopus 로고
    • Antiperoxidative effects of lycopene during N-methyl-N′-nitro-N- nitrosoguanidine-induced gastric carcinogenesis
    • DOI 10.1016/S0367-326X(02)00216-2, PII S0367326X02002162
    • Velmurugan B., Bhuvaneswari V., Nagini S., Antiperoxidative effects of lycopene during N-methyl-N′-nitro-N-nitrosoguanidine-induced gastric carcinogenesis. Fitoterapia 2002 73 7-8 604 611 2-s2.0-0036916637 10.1016/S0367-326X(02)00216-2 (Pubitemid 35477756)
    • (2002) Fitoterapia , vol.73 , Issue.7-8 , pp. 604-611
    • Velmurugan, B.1    Bhuvaneswari, V.2    Nagini, S.3
  • 29
    • 0035209696 scopus 로고    scopus 로고
    • Chemopreventive efficacy of lycopene on 7,12-dimethylbenz[a]anthracene- induced hamster buccal pouch carcinogenesis
    • DOI 10.1016/S0367-326X(01)00321-5, PII S0367326X01003215
    • Bhuvaneswari V., Velmurugan B., Balasenthil S., Ramachandran C. R., Nagini S., Chemopreventive efficacy of lycopene on 7,12-dimethylbenz[a] anthracene-induced hamster buccal pouch carcinogenesis. Fitoterapia 2001 72 8 865 874 2-s2.0-0035209696 10.1016/S0367-326X(01)00321-5 (Pubitemid 33122194)
    • (2001) Fitoterapia , vol.72 , Issue.8 , pp. 865-874
    • Bhuvaneswari, V.1    Velmurugan, B.2    Balasenthil, S.3    Ramachandran, C.R.4    Nagini, S.5
  • 30
    • 4544294365 scopus 로고    scopus 로고
    • The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: Oxidative stress sensing by a Cul3-Keap1 ligase
    • DOI 10.1128/MCB.24.19.8477-8486.2004
    • Cullinan S. B., Gordan J. D., Jin J., Harper J. W., Diehl J. A., The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase. Molecular and Cellular Biology 2004 24 19 8477 8486 2-s2.0-4544294365 10.1128/MCB.24.19.8477-8486.2004 (Pubitemid 39245070)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.19 , pp. 8477-8486
    • Cullinan, S.B.1    Gordan, J.D.2    Jin, J.3    Harper, J.W.4    Diehl, J.A.5
  • 31
    • 33847050801 scopus 로고    scopus 로고
    • Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
    • 2-s2.0-33847050801 10.1146/annurev.pharmtox.46.120604.141046
    • Kensler T. W., Wakabayashi N., Biswal S., Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annual Review of Pharmacology and Toxicology 2007 47 89 116 2-s2.0-33847050801 10.1146/annurev.pharmtox.46.120604.141046
    • (2007) Annual Review of Pharmacology and Toxicology , vol.47 , pp. 89-116
    • Kensler, T.W.1    Wakabayashi, N.2    Biswal, S.3
  • 32
    • 49749133236 scopus 로고    scopus 로고
    • Enzymatic metabolites of lycopene induce Nrf2-mediated expression of phase II detoxifying/antioxidant enzymes in human bronchial epithelial cells
    • 2-s2.0-49749133236 10.1002/ijc.23696
    • Lian F., Wang X.-D., Enzymatic metabolites of lycopene induce Nrf2-mediated expression of phase II detoxifying/antioxidant enzymes in human bronchial epithelial cells. International Journal of Cancer 2008 123 6 1262 1268 2-s2.0-49749133236 10.1002/ijc.23696
    • (2008) International Journal of Cancer , vol.123 , Issue.6 , pp. 1262-1268
    • Lian, F.1    Wang, X.-D.2
  • 33
    • 1942455887 scopus 로고    scopus 로고
    • Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles
    • DOI 10.1016/j.freeradbiomed.2004.02.075, PII S0891584904001935
    • Itoh K., Tong K. I., Yamamoto M., Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles. Free Radical Biology and Medicine 2004 36 10 1208 1213 2-s2.0-1942455887 10.1016/j.freeradbiomed.2004.02.075 (Pubitemid 38526314)
    • (2004) Free Radical Biology and Medicine , vol.36 , Issue.10 , pp. 1208-1213
    • Itoh, K.1    Tong, K.I.2    Yamamoto, M.3
  • 34
    • 41449112375 scopus 로고    scopus 로고
    • Acrolein induces heme oxygenase-1 through PKC-δ and PI3K in human bronchial epithelial cells
    • DOI 10.1165/rcmb.2007-0260OC
    • Zhang H., Forman H. J., Acrolein induces heme oxygenase-1 through PKC- δ and PI3K in human bronchial epithelial cells. American Journal of Respiratory Cell and Molecular Biology 2008 38 4 483 490 2-s2.0-41449112375 10.1165/rcmb.2007-0260OC (Pubitemid 351758695)
    • (2008) American Journal of Respiratory Cell and Molecular Biology , vol.38 , Issue.4 , pp. 483-490
    • Zhang, H.1    Forman, H.J.2
  • 35
    • 33644649422 scopus 로고    scopus 로고
    • Hyperoxia stimulates an Nrf2-ARE transcriptional response via ROS-EGFR-P13K-Akt/ERK MAP kinase signaling in pulmonary epithelial cells
    • DOI 10.1089/ars.2006.8.43
    • Papaiahgari S., Zhang Q., Kleeberger S. R., Cho H.-Y., Reddy S. P., Hyperoxia stimulates an Nrf2-ARE transcriptional response via ROS-EGFR-P13K-Akt/ERK MAP kinase signaling in pulmonary epithelial cells. Antioxidants and Redox Signaling 2006 8 1-2 43 52 2-s2.0-33644649422 10.1089/ars.2006.8.43 (Pubitemid 43324529)
    • (2006) Antioxidants and Redox Signaling , vol.8 , Issue.1-2 , pp. 43-52
    • Papaiahgari, S.1    Zhang, Q.2    Kleeberger, S.R.3    Cho, H.-Y.4    Reddy, S.P.5
  • 37
    • 0028029856 scopus 로고
    • Insulin receptor substrate-1 (IRS-1) distribution in the rat central nervous system
    • Folli F., Bonfanti L., Renard E., Kahn C. R., Merighi A., Insulin receptor substrate-1 (IRS-1) distribution in the rat central nervous system. Journal of Neuroscience 1994 14 11, part 1 6412 6422 2-s2.0-0028029856 (Pubitemid 24333063)
    • (1994) Journal of Neuroscience , vol.14 , Issue.11 , pp. 6412-6422
    • Folli, F.1    Bonfanti, L.2    Renard, E.3    Kahn, C.R.4    Merighi, A.5
  • 38
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: Biological actions
    • 2-s2.0-0028958031
    • Jones J. I., Clemmons D. R., Insulin-like growth factors and their binding proteins: biological actions. Endocrine Reviews 1995 16 1 3 34 2-s2.0-0028958031
    • (1995) Endocrine Reviews , vol.16 , Issue.1 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 40
    • 0032721707 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 (IGFBP-3) and risk of cancer
    • Giovannucci E., Insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 (IGFBP-3) and risk of cancer. Hormone Research 1999 51 34 41
    • (1999) Hormone Research , vol.51 , pp. 34-41
    • Giovannucci, E.1
  • 41
    • 0028863013 scopus 로고
    • Lycopene is a more potent inhibitor of human cancer cell proliferation than either α -carotene or β -carotene
    • 2-s2.0-0028863013
    • Levy J., Bosin E., Feldman B., Giat Y., Miinster A., Danilenko M., Sharoni Y., Lycopene is a more potent inhibitor of human cancer cell proliferation than either α -carotene or β -carotene. Nutrition and Cancer 1995 24 3 257 266 2-s2.0-0028863013
    • (1995) Nutrition and Cancer , vol.24 , Issue.3 , pp. 257-266
    • Levy, J.1    Bosin, E.2    Feldman, B.3    Giat, Y.4    Miinster, A.5    Danilenko, M.6    Sharoni, Y.7
  • 43
    • 0038407714 scopus 로고    scopus 로고
    • Lycopene supplementation inhibits lung squamous metaplasia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in cigarette smoke-exposed ferrets
    • Liu C., Lian F., Smith D. E., Russell R. M., Wang X.-D., Lycopene supplementation inhibits lung squamous metaplasia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in cigarette smoke-exposed ferrets. Cancer Research 2003 63 12 3138 3144 2-s2.0-0038407714 (Pubitemid 36735865)
    • (2003) Cancer Research , vol.63 , Issue.12 , pp. 3138-3144
    • Liu, C.1    Lian, F.2    Smith, D.E.3    Russell, R.M.4    Wang, X.-D.5
  • 44
    • 79951471546 scopus 로고    scopus 로고
    • Lycopene enhances docetaxel's effect in castration-resistant prostate cancer associated with insulin-like growth factor i receptor levels
    • 2-s2.0-79951471546 10.1593/neo.101092
    • Tang Y., Parmakhtiar B., Simoneau A. R., Xie J., Fruehauf J., Lilly M., Zi X., Lycopene enhances docetaxel's effect in castration-resistant prostate cancer associated with insulin-like growth factor I receptor levels. Neoplasia 2011 13 2 108 119 2-s2.0-79951471546 10.1593/neo.101092
    • (2011) Neoplasia , vol.13 , Issue.2 , pp. 108-119
    • Tang, Y.1    Parmakhtiar, B.2    Simoneau, A.R.3    Xie, J.4    Fruehauf, J.5    Lilly, M.6    Zi, X.7
  • 45
    • 0037085234 scopus 로고    scopus 로고
    • New members of the platelet-derived growth factor family of mitogens
    • DOI 10.1006/abbi.2001.2707
    • Heldin C.-H., Eriksson U., Östman A., New members of the platelet-derived growth factor family of mitogens. Archives of Biochemistry and Biophysics 2002 398 2 284 290 2-s2.0-0037085234 10.1006/abbi.2001.2707 (Pubitemid 34848597)
    • (2002) Archives of Biochemistry and Biophysics , vol.398 , Issue.2 , pp. 284-290
    • Heldin, C.-H.1    Eriksson, U.2    Ostman, A.3
  • 46
    • 0142243109 scopus 로고    scopus 로고
    • Roles of PDGF in animal development
    • DOI 10.1242/dev.00721
    • Hoch R. V., Soriano P., Roles of PDGF in animal development. Development 2003 130 20 4769 4784 2-s2.0-0142243109 10.1242/dev.00721 (Pubitemid 37321862)
    • (2003) Development , vol.130 , Issue.20 , pp. 4769-4784
    • Hoch, R.V.1    Soriano, P.2
  • 47
    • 34249110578 scopus 로고    scopus 로고
    • Lycopene binds PDGF-BB and inhibits PDGF-BB-induced intracellular signaling transduction pathway in rat smooth muscle cells
    • DOI 10.1016/j.bcp.2007.03.017, PII S0006295207001840
    • Lo H.-M., Hung C.-F., Tseng Y.-L., Chen B.-H., Jian J.-S., Wu W.-B., Lycopene binds PDGF-BB and inhibits PDGF-BB-induced intracellular signaling transduction pathway in rat smooth muscle cells. Biochemical Pharmacology 2007 74 1 54 63 2-s2.0-34249110578 10.1016/j.bcp.2007.03.017 (Pubitemid 46802489)
    • (2007) Biochemical Pharmacology , vol.74 , Issue.1 , pp. 54-63
    • Lo, H.-M.1    Hung, C.-F.2    Tseng, Y.-L.3    Chen, B.-H.4    Jian, J.-S.5    Wu, W.-B.6
  • 48
    • 0347990559 scopus 로고    scopus 로고
    • Mechanism of Human Dermal Fibroblast Migration Driven by Type I Collagen and Platelet-derived Growth Factor-BB
    • DOI 10.1091/mbc.E03-05-0352
    • Li W., Fan J., Chen M., Guan S., Sawcer D., Bokoch G. M., Woodley D. T., Mechanism of human dermal fibroblast migration driven by type I collagen and platelet-derived growth factor-BB. Molecular Biology of the Cell 2004 15 1 294 309 2-s2.0-0347990559 10.1091/mbc.E03-05-0352 (Pubitemid 38044964)
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.1 , pp. 294-309
    • Li, W.1    Fan, J.2    Chen, M.3    Guan, S.4    Sawcer, D.5    Bokoch, G.M.6    Woodley, D.T.7
  • 49
    • 77953231676 scopus 로고    scopus 로고
    • Lycopene binding compromised PDGF-AA/-AB signaling and migration in smooth muscle cells and fibroblasts: Prediction of the possible lycopene binding site within PDGF
    • 2-s2.0-77953231676 10.1007/s00210-010-0501-1
    • Chen C.-P., Hung C.-F., Lee S.-C., Lo H.-M., Wu P.-H., Wu W.-B., Lycopene binding compromised PDGF-AA/-AB signaling and migration in smooth muscle cells and fibroblasts: prediction of the possible lycopene binding site within PDGF. Naunyn-Schmiedeberg's Archives of Pharmacology 2010 381 5 401 414 2-s2.0-77953231676 10.1007/s00210-010-0501-1
    • (2010) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.381 , Issue.5 , pp. 401-414
    • Chen, C.-P.1    Hung, C.-F.2    Lee, S.-C.3    Lo, H.-M.4    Wu, P.-H.5    Wu, W.-B.6
  • 50
    • 36048994255 scopus 로고    scopus 로고
    • Lycopene inhibits PDGF-BB-induced signaling and migration in human dermal fibroblasts through interaction with PDGF-BB
    • DOI 10.1016/j.lfs.2007.09.018, PII S0024320507007175
    • Chiang H.-S., Wu W.-B., Fang J.-Y., Chen D.-F., Chen B.-H., Huang C.-C., Chen Y.-T., Hung C.-F., Lycopene inhibits PDGF-BB-induced signaling and migration in human dermal fibroblasts through interaction with PDGF-BB. Life Sciences 2007 81 21-22 1509 1517 2-s2.0-36048994255 10.1016/j.lfs.2007.09.018 (Pubitemid 350081040)
    • (2007) Life Sciences , vol.81 , Issue.21-22 , pp. 1509-1517
    • Chiang, H.-S.1    Wu, W.-B.2    Fang, J.-Y.3    Chen, D.-F.4    Chen, B.-H.5    Huang, C.-C.6    Chen, Y.-T.7    Hung, C.-F.8
  • 51
    • 0035003384 scopus 로고    scopus 로고
    • Structure and function of VEGF/VEGF-receptor system involved in angiogenesis
    • DOI 10.1247/csf.26.25
    • Shibuya M., Structure and function of VEGF/VEGF-receptor system involved in angiogenesis. Cell Structure and Function 2001 26 1 25 35 2-s2.0-0035003384 10.1247/csf.26.25 (Pubitemid 32421949)
    • (2001) Cell Structure and Function , vol.26 , Issue.1 , pp. 25-35
    • Shibuya, M.1
  • 52
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • Risau W., Mechanisms of angiogenesis. Nature 1997 386 6626 671 674 2-s2.0-0030952289 (Pubitemid 27193480)
    • (1997) Nature , vol.386 , Issue.6626 , pp. 671-674
    • Risau, W.1
  • 53
    • 84856451575 scopus 로고    scopus 로고
    • Effects of lycopene and apigenin on human umbilical vein endothelial cells in vitro under angiogenic stimulation
    • 10.1016/j.acthis.2011.03.004
    • Şahin M., Şahin E., Gümüşlü S., Effects of lycopene and apigenin on human umbilical vein endothelial cells in vitro under angiogenic stimulation. Acta Histochemica 2012 114 2 94 100 10.1016/j.acthis.2011.03.004
    • (2012) Acta Histochemica , vol.114 , Issue.2 , pp. 94-100
    • Şahin, M.1    Şahin, E.2    Gümüşlü, S.3
  • 54
    • 79953309675 scopus 로고    scopus 로고
    • Growth inhibitory efficacy of lycopene and β -carotene against androgen-independent prostate tumor cells xenografted in nude mice
    • 2-s2.0-79953309675 10.1002/mnfr.201000308
    • Yang C.-M., Yen Y.-T., Huang C.-S., Hu M.-L., Growth inhibitory efficacy of lycopene and β -carotene against androgen-independent prostate tumor cells xenografted in nude mice. Molecular Nutrition & Food Research 2011 55 4 606 612 2-s2.0-79953309675 10.1002/mnfr.201000308
    • (2011) Molecular Nutrition & Food Research , vol.55 , Issue.4 , pp. 606-612
    • Yang, C.-M.1    Yen, Y.-T.2    Huang, C.-S.3    Hu, M.-L.4
  • 55
    • 84862560347 scopus 로고    scopus 로고
    • Lycopene inhibis angiogenesis both in vitro and in vivo by inhibiting MMP-2/uPA system through VEGFR2-mediated PI3K-AKT and ERK/p38 signaling pathways
    • 10.1002/mnfr.201100683
    • Chen M. L., Lin Y. H., Yang C. M., Hu M. L., Lycopene inhibis angiogenesis both in vitro and in vivo by inhibiting MMP-2/uPA system through VEGFR2-mediated PI3K-AKT and ERK/p38 signaling pathways. Molecular Nutrition & Food Research 2012 56 5 889 899 10.1002/mnfr.201100683
    • (2012) Molecular Nutrition & Food Research , vol.56 , Issue.5 , pp. 889-899
    • Chen, M.L.1    Lin, Y.H.2    Yang, C.M.3    Hu, M.L.4
  • 56
    • 0842324788 scopus 로고    scopus 로고
    • Recycling the Cell Cycle: Cyclins Revisited
    • DOI 10.1016/S0092-8674(03)01080-8
    • Murray A. W., Recycling the cell cycle: cyclins revisited. Cell 2004 116 2 221 234 2-s2.0-0842324788 10.1016/S0092-8674(03)01080-8 (Pubitemid 38167314)
    • (2004) Cell , vol.116 , Issue.2 , pp. 221-234
    • Murray, A.W.1
  • 57
    • 34247149015 scopus 로고    scopus 로고
    • The regulation of cyclin D1 degradation: Roles in cancer development and the potential for therapeutic invention
    • DOI 10.1186/1476-4598-6-24
    • Alao J. P., The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention. Molecular Cancer 2007 6, article 24 2-s2.0-34247149015 10.1186/1476-4598-6-24 (Pubitemid 46585441)
    • (2007) Molecular Cancer , vol.6 , pp. 24
    • Alao, J.P.1
  • 58
    • 0034660892 scopus 로고    scopus 로고
    • The pezcoller lecture: Cancer cell cycles revisited
    • Sherr C. J., The pezcoller lecture: cancer cell cycles revisited. Cancer Research 2000 60 14 3689 3695 2-s2.0-0034660892 (Pubitemid 32204552)
    • (2000) Cancer Research , vol.60 , Issue.14 , pp. 3689-3695
    • Sherr, C.J.1
  • 59
    • 30644470449 scopus 로고    scopus 로고
    • The effect of lycopene on cell growth and oxidative DNA damage of Hep3B human hepatoma cells
    • Park Y. O., Hwang E.-S., Moon T. W., The effect of lycopene on cell growth and oxidative DNA damage of Hep3B human hepatoma cells. BioFactors 2005 23 3 129 139 2-s2.0-30644470449 10.1002/biof.5520230302 (Pubitemid 43086340)
    • (2005) BioFactors , vol.23 , Issue.3 , pp. 129-139
    • Yun, O.P.1    Hwang, E.-S.2    Tae, W.M.3
  • 60
    • 0035821778 scopus 로고    scopus 로고
    • Kip1 in the cyclin E-cdk2 complexes
    • DOI 10.1038/sj.onc.1204452
    • Nahum A., Hirsch K., Danilenko M., Watts C. K. W., Prall O. W. J., Levy J., Sharoni Y., Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27 Kip1 in the cyclin E-cdk2 complexes. Oncogene 2001 20 26 3428 3436 2-s2.0-0035821778 10.1038/sj.onc.1204452 (Pubitemid 32588991)
    • (2001) Oncogene , vol.20 , Issue.26 , pp. 3428-3436
    • Nahum, A.1    Hirsch, K.2    Danilenko, M.3    Watts, C.K.W.4    Prall, O.W.J.5    Levy, J.6    Sharoni, Y.7
  • 61
    • 33746773068 scopus 로고    scopus 로고
    • Lycopene inhibition of IGF-induced cancer cell growth depends on the level of cyclin D1
    • DOI 10.1007/s00394-006-0595-x
    • Nahum A., Zeller L., Danilenko M., Prall O. W. J., Watts C. K. W., Sutherland R. L., Levy J., Sharoni Y., Lycopene inhibition of IGF-induced cancer cell growth depends on the level of cyclin D1. European Journal of Nutrition 2006 45 5 275 282 2-s2.0-33746773068 10.1007/s00394-006-0595-x (Pubitemid 44167661)
    • (2006) European Journal of Nutrition , vol.45 , Issue.5 , pp. 275-282
    • Nahum, A.1    Zeller, L.2    Danilenko, M.3    Prall, O.W.J.4    Watts, C.K.W.5    Sutherland, R.L.6    Levy, J.7    Sharoni, Y.8
  • 62
    • 17144452288 scopus 로고    scopus 로고
    • Lycopene interferes with cell cycle progression and insulin-like growth factor I signaling in mammary cancer cells
    • Karas M., Amir H., Fishman D., Danilenko M., Segal S., Nahum A., Koifmann A., Giat Y., Levy J., Sharoni Y., Lycopene interferes with cell cycle progression and insulin-like growth factor I signaling in mammary cancer cells. Nutrition and Cancer 2000 36 1 101 111 2-s2.0-17144452288 (Pubitemid 30317841)
    • (2000) Nutrition and Cancer , vol.36 , Issue.1 , pp. 101-111
    • Karas, M.1    Amir, H.2    Fishman, D.3    Danilenko, M.4    Segal, S.5    Nahum, A.6    Koifmann, A.7    Giat, Y.8    Levy, J.9    Sharoni, Y.10
  • 63
    • 77957757788 scopus 로고    scopus 로고
    • Lycopene induces cell growth inhibition by altering mevalonate pathway and Ras signaling in cancer cell lines
    • 2-s2.0-77957757788 10.1093/carcin/bgq157
    • Palozza P., Colangelo M., Simone R., Catalano A., Boninsegna A., Lanza P., Monego G., Ranelletti F. O., Lycopene induces cell growth inhibition by altering mevalonate pathway and Ras signaling in cancer cell lines. Carcinogenesis 2010 31 10 1813 1821 2-s2.0-77957757788 10.1093/carcin/bgq157
    • (2010) Carcinogenesis , vol.31 , Issue.10 , pp. 1813-1821
    • Palozza, P.1    Colangelo, M.2    Simone, R.3    Catalano, A.4    Boninsegna, A.5    Lanza, P.6    Monego, G.7    Ranelletti, F.O.8
  • 64
    • 79954959102 scopus 로고    scopus 로고
    • Development of natural anti-tumor drugs by microorganisms
    • 2-s2.0-79954959102 10.1016/j.jbiosc.2010.12.026
    • Chang C.-C., Chen W.-C., Ho T.-F., Wu H.-S., Wei Y.-H., Development of natural anti-tumor drugs by microorganisms. Journal of Bioscience and Bioengineering 2011 111 5 501 511 2-s2.0-79954959102 10.1016/j.jbiosc.2010.12. 026
    • (2011) Journal of Bioscience and Bioengineering , vol.111 , Issue.5 , pp. 501-511
    • Chang, C.-C.1    Chen, W.-C.2    Ho, T.-F.3    Wu, H.-S.4    Wei, Y.-H.5
  • 65
    • 84866854512 scopus 로고    scopus 로고
    • Skp2 is a promising therapeutic target in breast cancer
    • PII 18702 10.3389/fonc.2011.00057
    • Wang Z., Fukushima H., Inuzuka H., Skp2 is a promising therapeutic target in breast cancer. Frontiers in Oncology 2012 1 57, pii 18702 10.3389/fonc.2011.00057
    • (2012) Frontiers in Oncology , vol.1 , Issue.57
    • Wang, Z.1    Fukushima, H.2    Inuzuka, H.3
  • 66
    • 34547800757 scopus 로고    scopus 로고
    • Apo-10′-lycopenoic acid inhibits lung cancer cell growth in vitro, and suppresses lung tumorigenesis in the A/J mouse model in vivo
    • DOI 10.1093/carcin/bgm076
    • Lian F., Smith D. E., Ernst H., Russell R. M., Wang X.-D., Apo-10′-lycopenoic acid inhibits lung cancer cell growth in vitro, and suppresses lung tumorigenesis in the A/J mouse model in vivo. Carcinogenesis 2007 28 7 1567 1574 2-s2.0-34547800757 10.1093/carcin/bgm076 (Pubitemid 47241807)
    • (2007) Carcinogenesis , vol.28 , Issue.7 , pp. 1567-1574
    • Lian, F.1    Smith, D.E.2    Ernst, H.3    Russell, R.M.4    Wang, X.-D.5
  • 67
    • 79951864386 scopus 로고    scopus 로고
    • Lycopene and apo-12′-lycopenal reduce cell proliferation and alter cell cycle progression in human prostate cancer cells
    • 2-s2.0-79951864386 10.1080/01635581.2011.523494
    • Ford N. A., Elsen A. C., Zuniga K., Lindshield B. L., Erdman J. W. Jr., Lycopene and apo-12′-lycopenal reduce cell proliferation and alter cell cycle progression in human prostate cancer cells. Nutrition and Cancer 2011 63 2 256 263 2-s2.0-79951864386 10.1080/01635581.2011.523494
    • (2011) Nutrition and Cancer , vol.63 , Issue.2 , pp. 256-263
    • Ford, N.A.1    Elsen, A.C.2    Zuniga, K.3    Lindshield, B.L.4    Erdman Jr., J.W.5
  • 68
    • 3442886811 scopus 로고    scopus 로고
    • The pathophysiology of mitochondrial cell death
    • DOI 10.1126/science.1099320
    • Green D. R., Kroemer G., The pathophysiology of mitochondrial cell death. Science 2004 305 5684 626 629 2-s2.0-3442886811 10.1126/science.1099320 (Pubitemid 39006738)
    • (2004) Science , vol.305 , Issue.5684 , pp. 626-629
    • Green, D.R.1    Kroemer, G.2
  • 69
    • 24744454606 scopus 로고    scopus 로고
    • A mechanism for death receptor discrimination by death adaptors
    • DOI 10.1074/jbc.M506938200
    • Sandu C., Gavathiotis E., Huang T., Wegorzewska I., Werner M. H., A mechanism for death receptor discrimination by death adaptors. The Journal of Biological Chemistry 2005 280 36 31974 31980 2-s2.0-24744454606 10.1074/jbc.M506938200 (Pubitemid 41291948)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.36 , pp. 31974-31980
    • Sandu, C.1    Gavathiotis, E.2    Huang, T.3    Wegorzewska, I.4    Werner, M.H.5
  • 70
    • 25844490942 scopus 로고    scopus 로고
    • The Fas-associated death domain protein/caspase-8/c-FLIP signaling pathway is involved in TNF-induced activation of ERK
    • DOI 10.1016/j.yexcr.2005.07.022, PII S0014482705003241
    • Lüschen S., Falk M., Scherer G., Ussat S., Paulsen M., Adam-Klages S., The Fas-associated death domain protein/caspase-8/c-FLIP signaling pathway is involved in TNF-induced activation of ERK. Experimental Cell Research 2005 310 1 33 42 2-s2.0-25844490942 10.1016/j.yexcr.2005.07.022 (Pubitemid 41393685)
    • (2005) Experimental Cell Research , vol.310 , Issue.1 , pp. 33-42
    • Luschen, S.1    Falk, M.2    Scherer, G.3    Ussat, S.4    Paulsen, M.5    Adam-Klages, S.6
  • 71
    • 4444324090 scopus 로고    scopus 로고
    • Apoptosis and disease: A life or death decision. Conference and workshop on apoptosis and disease
    • DOI 10.1038/sj.embor.7400191
    • MacFarlane M., Williams A. C., Apoptosis and disease: a life or death decision. European Molecular Biology Organitation Reports 2004 5 7 674 678 2-s2.0-4444324090 10.1038/sj.embor.7400191 (Pubitemid 39173000)
    • (2004) EMBO Reports , vol.5 , Issue.7 , pp. 674-678
    • MacFarlane, M.1    Williams, A.C.2
  • 72
    • 0036204018 scopus 로고    scopus 로고
    • Cell death regulation by the mammalian IAP antagonist Diablo/Smac
    • DOI 10.1023/A:1014318615955
    • Verhagen A. M., Vaux D. L., Cell death regulation by the mammalian IAP antagonist Diablo/Smac. Apoptosis 2002 7 2 163 166 2-s2.0-0036204018 10.1023/A:1014318615955 (Pubitemid 34273131)
    • (2002) Apoptosis , vol.7 , Issue.2 , pp. 163-166
    • Verhagen, A.M.1    Vaux, D.L.2
  • 73
    • 0242319666 scopus 로고    scopus 로고
    • Apoptosis - The p53 network
    • DOI 10.1242/jcs.00739
    • Haupt S., Berger M., Goldberg Z., Haupt Y., Apoptosis-the p53 network. Journal of Cell Science 2003 116, part 20 4077 4085 2-s2.0-0242319666 10.1242/jcs.00739 (Pubitemid 37337082)
    • (2003) Journal of Cell Science , vol.116 , Issue.20 , pp. 4077-4085
    • Haupt, S.1    Berger, M.2    Goldberg, Z.3    Haupt, Y.4
  • 74
    • 67349125876 scopus 로고    scopus 로고
    • Concomitant supplementation of lycopene and eicosapentaenoic acid inhibits the proliferation of human colon cancer cells
    • 2-s2.0-67349125876 10.1016/j.jnutbio.2008.05.001
    • Tang F.-Y., Cho H.-J., Pai M.-H., Chen Y.-H., Concomitant supplementation of lycopene and eicosapentaenoic acid inhibits the proliferation of human colon cancer cells. The Journal of Nutritional Biochemistry 2009 20 6 426 434 2-s2.0-67349125876 10.1016/j.jnutbio.2008.05.001
    • (2009) The Journal of Nutritional Biochemistry , vol.20 , Issue.6 , pp. 426-434
    • Tang, F.-Y.1    Cho, H.-J.2    Pai, M.-H.3    Chen, Y.-H.4
  • 75
    • 23344447085 scopus 로고    scopus 로고
    • Combination of S-allylcysteine and lycopene induces apoptosis by modulating Bcl-2, Bax, Bim and caspases during experimental gastric carcinogenesis
    • DOI 10.1097/00008469-200508000-00012
    • Velmurugan B., Mani A., Nagini S., Combination of S-allylcysteine and lycopene induces apoptosis by modulating Bcl-2, Bax, Bim and caspases during experimental gastric carcinogenesis. European Journal of Cancer Prevention 2005 14 4 387 393 2-s2.0-23344447085 10.1097/00008469-200508000-00012 (Pubitemid 41104948)
    • (2005) European Journal of Cancer Prevention , vol.14 , Issue.4 , pp. 387-393
    • Velmurugan, B.1    Mani, A.2    Nagini, S.3
  • 76
    • 0346366738 scopus 로고    scopus 로고
    • A novel cleavage product formed by autoxidation of lycopene induces apoptosis in HL-60 cells
    • DOI 10.1016/j.freeradbiomed.2003.09.019
    • Zhang H., Kotake-Nara E., Ono H., Nagao A., A novel cleavage product formed by autoxidation of lycopene induces apoptosis in HL-60 cells. Free Radical Biology and Medicine 2003 35 12 1653 1663 2-s2.0-0346366738 10.1016/j.freeradbiomed.2003.09.019 (Pubitemid 37532916)
    • (2003) Free Radical Biology and Medicine , vol.35 , Issue.12 , pp. 1653-1663
    • Zhang, H.1    Kotake-Nara, E.2    Ono, H.3    Nagao, A.4
  • 77
    • 78149379720 scopus 로고    scopus 로고
    • Effects of lycopene on proliferation and death of canine osteosarcoma cells
    • 2-s2.0-78149379720 10.2460/ajvr.71.11.1362
    • Wakshlag J. J., Balkman C. E., Effects of lycopene on proliferation and death of canine osteosarcoma cells. American Journal of Veterinary Research 2010 71 11 1362 1370 2-s2.0-78149379720 10.2460/ajvr.71.11.1362
    • (2010) American Journal of Veterinary Research , vol.71 , Issue.11 , pp. 1362-1370
    • Wakshlag, J.J.1    Balkman, C.E.2
  • 78
    • 14344259481 scopus 로고    scopus 로고
    • Physiologically attainable concentrations of lycopene induce mitochondrial apoptosis in LNCaP human prostate cancer cells
    • Hantz H. L., Young L. F., Martin K. R., Physiologically attainable concentrations of lycopene induce mitochondrial apoptosis in LNCaP human prostate cancer cells. Experimental Biology and Medicine 2005 230 3 171 179 2-s2.0-14344259481 (Pubitemid 40293690)
    • (2005) Experimental Biology and Medicine , vol.230 , Issue.3 , pp. 171-179
    • Hantz, H.L.1    Young, L.F.2    Martin, K.R.3
  • 79
    • 84857134219 scopus 로고    scopus 로고
    • Inhibitory effects of combination of lycopene and genistein on 7,12- Dimethyl benz(a)anthracene-induced breast cancer in rats
    • 2-s2.0-84857134219 10.1080/01635581.2011.606955
    • Sahin K., Tuzcu M., Sahin N., Akdemir F., Ozercan I., Bayraktar S., Kucuk O., Inhibitory effects of combination of lycopene and genistein on 7,12- Dimethyl benz(a)anthracene-induced breast cancer in rats. Nutrition and Cancer 2011 63 8 1279 1286 2-s2.0-84857134219 10.1080/01635581.2011.606955
    • (2011) Nutrition and Cancer , vol.63 , Issue.8 , pp. 1279-1286
    • Sahin, K.1    Tuzcu, M.2    Sahin, N.3    Akdemir, F.4    Ozercan, I.5    Bayraktar, S.6    Kucuk, O.7
  • 80
    • 76449118095 scopus 로고    scopus 로고
    • Effect of lycopene on proliferation and cell cycle of hormone refractory prostate cancer PC-3 cell line
    • 2-s2.0-76449118095
    • Wang A., Zhang L., Effect of lycopene on proliferation and cell cycle of hormone refractory prostate cancer PC-3 cell line. Wei Sheng Yan Jiu 2007 36 5 575 578 2-s2.0-76449118095
    • (2007) Wei Sheng Yan Jiu , vol.36 , Issue.5 , pp. 575-578
    • Wang, A.1    Zhang, L.2
  • 81
    • 34748891785 scopus 로고    scopus 로고
    • The growth-inhibitory effects of tomatoes digested in vitro in colon adenocarcinoma cells occur through down regulation of cyclin D1, Bcl-2 and Bcl-xL
    • DOI 10.1017/S0007114507746883, PII S0007114507746883
    • Palozza P., Serini S., Boninsegna A., Bellovino D., Lucarini M., Monastra G., Gaetani S., The growth-inhibitory effects of tomatoes digested in vitro in colon adenocarcinoma cells occur through down regulation of cyclin D1, Bcl-2 and Bcl-xL. British Journal of Nutrition 2007 98 4 789 795 2-s2.0-34748891785 10.1017/S0007114507746883 (Pubitemid 47487946)
    • (2007) British Journal of Nutrition , vol.98 , Issue.4 , pp. 789-795
    • Palozza, P.1    Serini, S.2    Boninsegna, A.3    Bellovino, D.4    Lucarini, M.5    Monastra, G.6    Gaetani, S.7
  • 82
    • 30944458833 scopus 로고    scopus 로고
    • Lycopene induces apoptosis in immortalized fibroblasts exposed to tobacco smoke condensate through arresting cell cycle and down-regulating cyclin D1, pAKT and pBad
    • DOI 10.1007/s10495-005-1393-2
    • Palozza P., Sheriff A., Serini S., Boninsegna A., Maggiano N., Ranelletti F. O., Calviello G., Cittadini A., Lycopene induces apoptosis in immortalized fibroblasts exposed to tobacco smoke condensate through arresting cell cycle and down-regulating cyclin D1, pAKT and pBad. Apoptosis 2005 10 6 1445 1456 2-s2.0-30944458833 10.1007/s10495-005-1393-2 (Pubitemid 43117688)
    • (2005) Apoptosis , vol.10 , Issue.6 , pp. 1445-1456
    • Palozza, P.1    Sheriff, A.2    Serini, S.3    Boninsegna, A.4    Maggiano, N.5    Ranelletti, F.O.6    Calviello, G.7    Cittadini, A.8
  • 83
    • 79951471546 scopus 로고    scopus 로고
    • Lycopene enhances docetaxel's effect in castration-resistant prostate cancer associated with insulin-like growth factor i receptor levels
    • 2-s2.0-79951471546 10.1593/neo.101092
    • Tang Y., Parmakhtiar B., Simoneau A. R., Xie J., Fruehauf J., Lilly M., Zi X., Lycopene enhances docetaxel's effect in castration-resistant prostate cancer associated with insulin-like growth factor I receptor levels. Neoplasia 2011 13 2 108 119 2-s2.0-79951471546 10.1593/neo.101092
    • (2011) Neoplasia , vol.13 , Issue.2 , pp. 108-119
    • Tang, Y.1    Parmakhtiar, B.2    Simoneau, A.R.3    Xie, J.4    Fruehauf, J.5    Lilly, M.6    Zi, X.7
  • 84
    • 58249092965 scopus 로고    scopus 로고
    • Mechanisms of metastasis
    • 2-s2.0-58249092965 10.1186/bcr1988
    • Hunter K. W., Crawford N. P. S., Alsarraj J., Mechanisms of metastasis. Breast Cancer Research 2008 10, supplement 1, article S2 2-s2.0-58249092965 10.1186/bcr1988
    • (2008) Breast Cancer Research , vol.1012
    • Hunter, K.W.1    Crawford, N.P.S.2    Alsarraj, J.3
  • 87
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, β-Catenin, and Cadherin pathways
    • DOI 10.1126/science.1094291
    • Nelson W. J., Nusse R., Convergence of Wnt, β -catenin, and cadherin pathways. Science 2004 303 5663 1483 1487 2-s2.0-1542347695 10.1126/science.1094291 (Pubitemid 38314410)
    • (2004) Science , vol.303 , Issue.5663 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 89
    • 0033119801 scopus 로고    scopus 로고
    • β-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • DOI 10.1038/18884
    • Tetsu O., McCormick F., β -catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999 398 6726 422 426 2-s2.0-0033119801 10.1038/18884 (Pubitemid 29180374)
    • (1999) Nature , vol.398 , Issue.6726 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 90
    • 0344171934 scopus 로고    scopus 로고
    • The Wnt/Wg signal transducer β-catenin controls fibronectin expression
    • Gradl D., Kühl M., Wedlich D., The Wnt/Wg signal transducer β -catenin controls fibronectin expression. Molecular and Cellular Biology 1999 19 8 5576 5587 2-s2.0-0344171934 (Pubitemid 29339915)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.8 , pp. 5576-5587
    • Gradl, D.1    Kuhl, M.2    Wedlich, D.3
  • 91
    • 79956282901 scopus 로고    scopus 로고
    • Lycopene inhibits NF-KB-Mediated IL-8 expression and changes redox and PPAR γ signalling in cigarette smoke-stimulated macrophages
    • ARTICLE E19652 2-s2.0-79956282901 10.1371/journal.pone.0019652
    • Simone R. E., Russo M., Catalano A., Monego G., Froehlich K., Boehm V., Palozza P., Lycopene inhibits NF-KB-Mediated IL-8 expression and changes redox and PPAR γ signalling in cigarette smoke-stimulated macrophages. PLoS ONE 2011 6 5, article e19652 2-s2.0-79956282901 10.1371/journal.pone.0019652
    • (2011) PLoS ONE , vol.6 , Issue.5
    • Simone, R.E.1    Russo, M.2    Catalano, A.3    Monego, G.4    Froehlich, K.5    Boehm, V.6    Palozza, P.7
  • 92
    • 77949270779 scopus 로고    scopus 로고
    • Lycopene suppresses LPS-induced NO and IL-6 production by inhibiting the activation of ERK, p38MAPK, and NF- B in macrophages
    • 2-s2.0-77949270779 10.1007/s00011-009-0077-8
    • Feng D., Ling W.-H., Duan R.-D., Lycopene suppresses LPS-induced NO and IL-6 production by inhibiting the activation of ERK, p38MAPK, and NF- B in macrophages. Inflammation Research 2010 59 2 115 121 2-s2.0-77949270779 10.1007/s00011-009-0077-8
    • (2010) Inflammation Research , vol.59 , Issue.2 , pp. 115-121
    • Feng, D.1    Ling, W.-H.2    Duan, R.-D.3
  • 93
    • 33846968424 scopus 로고    scopus 로고
    • Lycopene inhibits LPS-induced proinflammatory mediator inducible nitric oxide synthase in mouse macrophage cells
    • 2-s2.0-38349085887 10.1111/j.1750-3841.2006.00219.x
    • Rafi M. M., Yadav P. N., Reyes M., Lycopene inhibits LPS-induced proinflammatory mediator inducible nitric oxide synthase in mouse macrophage cells. Journal of Food Science 2007 72 1 S069 S074 2-s2.0-38349085887 10.1111/j.1750-3841.2006.00219.x
    • (2007) Journal of Food Science , vol.72 , Issue.1
    • Rafi, M.M.1    Yadav, P.N.2    Reyes, M.3
  • 94
    • 80051743214 scopus 로고    scopus 로고
    • Consumption of lycopene inhibits the growth and progression of colon cancer in a mouse xenograft model
    • 2-s2.0-80051743214 10.1021/jf2017644
    • Tang F.-Y., Pai M.-H., Wang X.-D., Consumption of lycopene inhibits the growth and progression of colon cancer in a mouse xenograft model. Journal of Agricultural and Food Chemistry 2011 59 16 9011 9021 2-s2.0-80051743214 10.1021/jf2017644
    • (2011) Journal of Agricultural and Food Chemistry , vol.59 , Issue.16 , pp. 9011-9021
    • Tang, F.-Y.1    Pai, M.-H.2    Wang, X.-D.3
  • 95
    • 80054995016 scopus 로고    scopus 로고
    • Cancer chemopreventive effects of lycopene: Suppression of MMP-7 expression and cell invasion in human colon cancer cells
    • 2-s2.0-80054995016 10.1021/jf202433f
    • Lin M.-C., Wang F.-Y., Kuo Y.-H., Tang F.-Y., Cancer chemopreventive effects of lycopene: suppression of MMP-7 expression and cell invasion in human colon cancer cells. Journal of Agricultural and Food Chemistry 2011 59 20 11304 11318 2-s2.0-80054995016 10.1021/jf202433f
    • (2011) Journal of Agricultural and Food Chemistry , vol.59 , Issue.20 , pp. 11304-11318
    • Lin, M.-C.1    Wang, F.-Y.2    Kuo, Y.-H.3    Tang, F.-Y.4
  • 96
    • 49649112171 scopus 로고    scopus 로고
    • Lycopene inhibits growth of human colon cancer cells via suppression of the Akt signaling pathway
    • 2-s2.0-49649112171 10.1002/mnfr.200700272
    • Tang F.-Y., Shih C.-J., Cheng L.-H., Ho H.-J., Chen H.-J., Lycopene inhibits growth of human colon cancer cells via suppression of the Akt signaling pathway. Molecular Nutrition & Food Research 2008 52 6 646 654 2-s2.0-49649112171 10.1002/mnfr.200700272
    • (2008) Molecular Nutrition & Food Research , vol.52 , Issue.6 , pp. 646-654
    • Tang, F.-Y.1    Shih, C.-J.2    Cheng, L.-H.3    Ho, H.-J.4    Chen, H.-J.5
  • 97
    • 33644671562 scopus 로고    scopus 로고
    • Inhibitory effects of lycopene on the adhesion, invasion, and migration of SK-Hep1 human hepatoma cells
    • Hwang E.-S., Lee H. J., Inhibitory effects of lycopene on the adhesion, invasion, and migration of SK-Hep1 human hepatoma cells. Experimental Biology and Medicine 2006 231 3 322 327 2-s2.0-33644671562 (Pubitemid 43334319)
    • (2006) Experimental Biology and Medicine , vol.231 , Issue.3 , pp. 322-327
    • Hwang, E.-S.1    Hyong, J.L.2
  • 98
    • 24744436403 scopus 로고    scopus 로고
    • Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells
    • Huang C.-S., Shih M.-K., Chuang C.-H., Hu M.-L., Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells. Journal of Nutrition 2005 135 9 2119 2123 2-s2.0-24744436403 (Pubitemid 41298375)
    • (2005) Journal of Nutrition , vol.135 , Issue.9 , pp. 2119-2123
    • Huang, C.-S.1    Shih, M.-K.2    Chuang, C.-H.3    Hu, M.-L.4
  • 99
    • 40449110427 scopus 로고    scopus 로고
    • Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice
    • Huang C.-S., Liao J.-W., Hu M.-L., Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice. Journal of Nutrition 2008 138 3 538 543 2-s2.0-40449110427 (Pubitemid 351355254)
    • (2008) Journal of Nutrition , vol.138 , Issue.3 , pp. 538-543
    • Huang, C.-S.1    Liao, J.-W.2    Hu, M.-L.3
  • 100
    • 84862267642 scopus 로고    scopus 로고
    • Antimetastatic effects and mechanisms of apo-8′-lycopenal, an enzymatic metabolite of lycopene, against human hepatocellular carcinoma SK-Hep-1 cells
    • 10.1080/01635581.2012.643273
    • Yang C.-M., Hu T.-Y., Hu M.-L., Antimetastatic effects and mechanisms of apo-8′-lycopenal, an enzymatic metabolite of lycopene, against human hepatocellular carcinoma SK-Hep-1 cells. Nutrition and Cancer 2012 64 2 274 285 10.1080/01635581.2012.643273
    • (2012) Nutrition and Cancer , vol.64 , Issue.2 , pp. 274-285
    • Yang, C.-M.1    Hu, T.-Y.2    Hu, M.-L.3
  • 101
    • 34249913180 scopus 로고    scopus 로고
    • Lycopene inhibits matrix metalloproteinase-9 expression and down-regulates the binding activity of nuclear factor-kappa B and stimulatory protein-1
    • DOI 10.1016/j.jnutbio.2006.08.007, PII S0955286306001914
    • Huang C.-S., Fan Y.-E., Lin C.-Y., Hu M.-L., Lycopene inhibits matrix metalloproteinase-9 expression and down-regulates the binding activity of nuclear factor-kappa B and stimulatory protein-1. The Journal of Nutritional Biochemistry 2007 18 7 449 456 2-s2.0-34249913180 10.1016/j.jnutbio.2006.08.007 (Pubitemid 46874919)
    • (2007) Journal of Nutritional Biochemistry , vol.18 , Issue.7 , pp. 449-456
    • Huang, C.-S.1    Fan, Y.-E.2    Lin, C.-Y.3    Hu, M.-L.4
  • 102
    • 0033053127 scopus 로고    scopus 로고
    • Insulin-like growth factor I-triggered cell migration and invasion are mediated by matrix metalloproteinase-9
    • Mira E., Mañes S., Lacalle R. A., Márquez G., Martínez A. C., Insulin-like growth factor I-triggered cell migration and invasion are mediated by matrix metalloproteinase-9. Endocrinology 1999 140 4 1657 1664 2-s2.0-0033053127 (Pubitemid 29149234)
    • (1999) Endocrinology , vol.140 , Issue.4 , pp. 1657-1664
    • Mira, E.1    Manes, S.2    Lacalle, R.A.3    Marquez, G.4    Martinez-A, C.5
  • 103
    • 41849127826 scopus 로고    scopus 로고
    • Lycopene inhibits IGF-I signal transduction and growth in normal prostate epithelial cells by decreasing DHT-modulated IGF-I production in co-cultured reactive stromal cells
    • DOI 10.1093/carcin/bgn011
    • Liu X., Allen J. D., Arnold J. T., Blackman M. R., Lycopene inhibits IGF-I signal transduction and growth in normal prostate epithelial cells by decreasing DHT-modulated IGF-I production in co-cultured reactive stromal cells. Carcinogenesis 2008 29 4 816 823 2-s2.0-41849127826 10.1093/carcin/bgn011 (Pubitemid 351494170)
    • (2008) Carcinogenesis , vol.29 , Issue.4 , pp. 816-823
    • Liu, X.1    Allen, J.D.2    Arnold, J.T.3    Blackman, M.R.4
  • 104
    • 80052729401 scopus 로고    scopus 로고
    • The combination of serenoa repens, selenium and lycopene is more effective than serenoa repens alone to prevent hormone dependent prostatic growth
    • 2-s2.0-80052729401 10.1016/j.juro.2011.05.049
    • Altavilla D., Bitto A., Polito F., Irrera N., Marini H., Arena S., Favilla V., Squadrito F., Morgia G., Minutoli L., The combination of serenoa repens, selenium and lycopene is more effective than serenoa repens alone to prevent hormone dependent prostatic growth. Journal of Urology 2011 186 4 1524 1529 2-s2.0-80052729401 10.1016/j.juro.2011.05.049
    • (2011) Journal of Urology , vol.186 , Issue.4 , pp. 1524-1529
    • Altavilla, D.1    Bitto, A.2    Polito, F.3    Irrera, N.4    Marini, H.5    Arena, S.6    Favilla, V.7    Squadrito, F.8    Morgia, G.9    Minutoli, L.10
  • 107
    • 0030013405 scopus 로고    scopus 로고
    • 3
    • Christakos S., Raval-Pandya M., Wernyj R. P., Yang W., Genomic mechanisms involved in the pleiotropic actions of 1,25-dihydroxyvitamin D3. The Biochemical Journal 1996 316, part 2 361 371 2-s2.0-0030013405 (Pubitemid 26182127)
    • (1996) Biochemical Journal , vol.316 , Issue.2 , pp. 361-371
    • Christakos, S.1    Raval-Pandya, M.2    Wernyj, R.P.3    Yang, W.4
  • 108
    • 0033008852 scopus 로고    scopus 로고
    • 3 cooperate in the inhibition of cell cycle progression and induction of differentiation in HL-60 leukemic cells
    • Amir H., Karas M., Giat J., Danilenko M., Levy R., Yermiahu T., Levy J., Sharoni Y., Lycopene and 1,25-dihydroxyvitamin D3 cooperate in the inhibition of cell cycle progression and induction of differentiation in HL-60 leukemic cells. Nutrition and Cancer 1999 33 1 105 112 2-s2.0-0033008852 (Pubitemid 29196131)
    • (1999) Nutrition and Cancer , vol.33 , Issue.1 , pp. 105-112
    • Amir, H.1    Karas, M.2    Giat, J.3    Danilenko, M.4    Levy, R.5    Yermiahu, T.6    Levy, J.7    Sharoni, Y.8
  • 109
    • 84867047887 scopus 로고    scopus 로고
    • Concomitant consumption of lycopene and fish oil inhibits tumor growth and progression in a mouse xenograft model of colon cancer
    • 10.1002/mnfr.201200098
    • Tang F.-Y., Pai M.-H., Kuo Y.-H., Wang X.-D., Concomitant consumption of lycopene and fish oil inhibits tumor growth and progression in a mouse xenograft model of colon cancer. Molecular Nutrition & Food Research 2012 56 10 1520 1531 10.1002/mnfr.201200098
    • (2012) Molecular Nutrition & Food Research , vol.56 , Issue.10 , pp. 1520-1531
    • Tang, F.-Y.1    Pai, M.-H.2    Kuo, Y.-H.3    Wang, X.-D.4
  • 110
    • 0036122761 scopus 로고    scopus 로고
    • Prevention of N-methyl-N′-nitro-N-nitrosoguanidine and saturated sodium chloride-induced gastric carcinogenesis in Wistar rats by lycopene
    • DOI 10.1097/00008469-200202000-00004
    • Velmurugan B., Bhuvaneswari V., Burra U. K., Nagini S., Prevention of N-methyl-N′-nitro-N-nitrosoguanidine and saturated sodium chloride-induced gastric carcinogenesis in Wistar rats by lycopene. European Journal of Cancer Prevention 2002 11 1 19 26 2-s2.0-0036122761 10.1097/00008469-200202000-00004 (Pubitemid 34233073)
    • (2002) European Journal of Cancer Prevention , vol.11 , Issue.1 , pp. 19-26
    • Velmurugan, B.1    Bhuvaneswari, V.2    Burra, U.K.3    Nagini, S.4
  • 111
    • 84862243589 scopus 로고    scopus 로고
    • Synergistic effect of lycopene and tocopherol against oxidative stress and mammary tumorigenesis induced by 7,12-dimethyl[a]benzanthracene in female rats
    • 10.1177/0748233711416948
    • Al-Malki A. L., Moselhy S. S., Refai M. Y., Synergistic effect of lycopene and tocopherol against oxidative stress and mammary tumorigenesis induced by 7,12-dimethyl[a]benzanthracene in female rats. Toxicology and Industrial Health 2012 28 6 542 548 10.1177/0748233711416948
    • (2012) Toxicology and Industrial Health , vol.28 , Issue.6 , pp. 542-548
    • Al-Malki, A.L.1    Moselhy, S.S.2    Refai, M.Y.3
  • 112
    • 55649119104 scopus 로고    scopus 로고
    • Chemopreventive effect of lycopene alone or with melatonin against the genesis of oxidative stress and mammary tumors induced by 7,12 dimethyl(a)benzanthracene in sprague dawely female rats
    • 2-s2.0-55649119104 10.1007/s11010-008-9890-6
    • Moselhy S. S., Al Mslmani M. A. B., Chemopreventive effect of lycopene alone or with melatonin against the genesis of oxidative stress and mammary tumors induced by 7,12 dimethyl(a)benzanthracene in sprague dawely female rats. Molecular and Cellular Biochemistry 2008 319 1-2 175 180 2-s2.0-55649119104 10.1007/s11010-008-9890-6
    • (2008) Molecular and Cellular Biochemistry , vol.319 , Issue.1-2 , pp. 175-180
    • Moselhy, S.S.1    Al Mslmani, M.A.B.2
  • 113
    • 6944226818 scopus 로고    scopus 로고
    • Lycopene and vitamin E interfere with autocrine/paracrine loops in the Dunning prostate cancer model
    • DOI 10.1096/fj.03-1116fje
    • Siler U., Barella L., Spitzer V., Schnorr J., Lein M., Goralczyk R., Wertz K., Lycopene and vitamin E interfere with autocrine/paracrine loops in the Dunning prostate cancer model. FASEB Journal 2004 18 9 1019 1021 2-s2.0-6944226818 10.1096/fj.03-1116fje (Pubitemid 39561511)
    • (2004) FASEB Journal , vol.18 , Issue.9 , pp. 1019-1021
    • Siler, U.1    Barella, L.2    Spitzer, V.3    Schnorr, J.4    Lein, M.5    Goralczyk, R.6    Wertz, K.7
  • 114
    • 79957560881 scopus 로고    scopus 로고
    • A tomato lycopene complex protects the kidney from cisplatin-induced injury via affecting oxidative stress as well as Bax, Bcl-2, and HSPs expression
    • 2-s2.0-79957560881 10.1080/01635581.2011.535958
    • Dogukan A., Tuzcu M., Agca C. A., Gencoglu H., Sahin N., Onderci M., Ozercan I. H., Ilhan N., Kucuk O., Sahin K., A tomato lycopene complex protects the kidney from cisplatin-induced injury via affecting oxidative stress as well as Bax, Bcl-2, and HSPs expression. Nutrition and Cancer 2011 63 3 427 434 2-s2.0-79957560881 10.1080/01635581.2011.535958
    • (2011) Nutrition and Cancer , vol.63 , Issue.3 , pp. 427-434
    • Dogukan, A.1    Tuzcu, M.2    Agca, C.A.3    Gencoglu, H.4    Sahin, N.5    Onderci, M.6    Ozercan, I.H.7    Ilhan, N.8    Kucuk, O.9    Sahin, K.10
  • 115
    • 84873534116 scopus 로고    scopus 로고
    • Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC
    • 10.1093/carcin/bgs351
    • Preet R., Mohapatra P., Das D., Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC. Carcinogenesis 2013 34 2 277 286 10.1093/carcin/bgs351
    • (2013) Carcinogenesis , vol.34 , Issue.2 , pp. 277-286
    • Preet, R.1    Mohapatra, P.2    Das, D.3
  • 116
    • 84865090847 scopus 로고    scopus 로고
    • Lycopene and the LXR α agonist T0901317 synergistically inhibit the proliferation of androgen-independent prostate cancer cells via the PPAR γ -LXR α -ABCA1 pathway
    • 2-s2.0-82255193387 10.1016/j.jnutbio.2011.06.009
    • Yang C.-M., Lu Y.-L., Chen H.-Y., Hu M.-L., Lycopene and the LXR α agonist T0901317 synergistically inhibit the proliferation of androgen-independent prostate cancer cells via the PPAR γ -LXR α -ABCA1 pathway. The Journal of Nutritional Biochemistry 2012 23 9 1155 1162 2-s2.0-82255193387 10.1016/j.jnutbio.2011.06.009
    • (2012) The Journal of Nutritional Biochemistry , vol.23 , Issue.9 , pp. 1155-1162
    • Yang, C.-M.1    Lu, Y.-L.2    Chen, H.-Y.3    Hu, M.-L.4
  • 118
    • 83355172499 scopus 로고    scopus 로고
    • Lycopene inhibits the proliferation of androgen-dependent human prostate tumor cells through activation of PPAR γ -LXR α -ABCA1 pathway
    • 2-s2.0-83355172499 10.1016/j.jnutbio.2010.10.006
    • Yang C.-M., Lu I.-H., Chen H.-Y., Hu M.-L., Lycopene inhibits the proliferation of androgen-dependent human prostate tumor cells through activation of PPAR γ -LXR α -ABCA1 pathway. The Journal of Nutritional Biochemistry 2012 23 1 8 17 2-s2.0-83355172499 10.1016/j.jnutbio. 2010.10.006
    • (2012) The Journal of Nutritional Biochemistry , vol.23 , Issue.1 , pp. 8-17
    • Yang, C.-M.1    Lu, I.-H.2    Chen, H.-Y.3    Hu, M.-L.4
  • 119
    • 84866922242 scopus 로고    scopus 로고
    • Anticancer activity of the cholesterol exporter ABCA1 gene
    • Smith B., Land H., Anticancer activity of the cholesterol exporter ABCA1 gene. Cell Reports 2012 2 3 580 590
    • (2012) Cell Reports , vol.2 , Issue.3 , pp. 580-590
    • Smith, B.1    Land, H.2
  • 120
    • 77952486015 scopus 로고    scopus 로고
    • Lycopene in the prevention of gastrointestinal toxicity of radiotherapy
    • 2-s2.0-77952486015 10.1080/01635580903285171
    • Andic F., Garipagaoglu M., Yurdakonar E., Tuncel N., Kucuk O., Lycopene in the prevention of gastrointestinal toxicity of radiotherapy. Nutrition and Cancer 2009 61 6 784 788 2-s2.0-77952486015 10.1080/01635580903285171
    • (2009) Nutrition and Cancer , vol.61 , Issue.6 , pp. 784-788
    • Andic, F.1    Garipagaoglu, M.2    Yurdakonar, E.3    Tuncel, N.4    Kucuk, O.5
  • 121
    • 67649338399 scopus 로고    scopus 로고
    • Lycopene: An antioxidant and radioprotector against γ -radiation-induced cellular damages in cultured human lymphocytes
    • 2-s2.0-67649338399 10.1016/j.tox.2009.05.004
    • Srinivasan M., Devipriya N., Kalpana K. B., Menon V. P., Lycopene: an antioxidant and radioprotector against γ -radiation-induced cellular damages in cultured human lymphocytes. Toxicology 2009 262 1 43 49 2-s2.0-67649338399 10.1016/j.tox.2009.05.004
    • (2009) Toxicology , vol.262 , Issue.1 , pp. 43-49
    • Srinivasan, M.1    Devipriya, N.2    Kalpana, K.B.3    Menon, V.P.4
  • 122
    • 2342507131 scopus 로고    scopus 로고
    • Protective Effects of Lycopene Against Ultraviolet B-Induced Photodamage
    • Fazekas Z., Gao D., Saladi R. N., Lu Y., Lebwohl M., Wei H., Protective effects of lycopene against ultraviolet B-induced photodamage. Nutrition and Cancer 2003 47 2 181 187 2-s2.0-2342507131 (Pubitemid 38590891)
    • (2003) Nutrition and Cancer , vol.47 , Issue.2 , pp. 181-187
    • Fazekas, Z.1    Gao, D.2    Saladi, R.N.3    Lu, Y.4    Lebwohl, M.5    Wei, H.6
  • 123
    • 84883775426 scopus 로고    scopus 로고
    • Synergic effect of curcumin or lycopene with irradiation upon oral squamous cell carcinoma cells
    • 10.1111/odi.12025
    • Camacho-Alonso F., López-Jornet P., Tudela-Mulero M., Synergic effect of curcumin or lycopene with irradiation upon oral squamous cell carcinoma cells. Oral Diseases 2013 19 5 465 472 10.1111/odi.12025
    • (2013) Oral Diseases , vol.19 , Issue.5 , pp. 465-472
    • Camacho-Alonso, F.1    López-Jornet, P.2    Tudela-Mulero, M.3
  • 124
    • 77951205496 scopus 로고    scopus 로고
    • Ingestion of selenium and other antioxidants during prostate cancer radiotherapy: A good thing?
    • 2-s2.0-77951205496 10.1016/j.ctrv.2009.12.008
    • Tabassum A., Bristow R. G., Venkateswaran V., Ingestion of selenium and other antioxidants during prostate cancer radiotherapy: a good thing? Cancer Treatment Reviews 2010 36 3 230 234 2-s2.0-77951205496 10.1016/j.ctrv.2009.12. 008
    • (2010) Cancer Treatment Reviews , vol.36 , Issue.3 , pp. 230-234
    • Tabassum, A.1    Bristow, R.G.2    Venkateswaran, V.3


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