Lycopene binding compromised PDGF-AA/-AB signaling and migration in smooth muscle cells and fibroblasts: Prediction of the possible lycopene binding site within PDGF

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 381, Issue 5, 2010, Pages 401-414

  Chen, Ching Pei ^a   Hung, Chi Feng ^b   Lee, Shao Chen ^b   Lo, Huey Ming ^b,c   Wu, Pi Hui ^b   Wu, Wen Bin ^b  

^a CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^b FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^c SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Binding; Lycopene; Migration; PDGF; Signaling; Tomato

Indexed keywords

BETA CAROTENE; HYDROGEN PEROXIDE; LYCOPENE; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR AB; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN KINASE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BINDING SITE; CELL COMMUNICATION; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG PROTEIN BINDING; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MOLECULAR DOCKING; NONHUMAN; PREDICTION; PROTEIN PHOSPHORYLATION; RAT; SMOOTH MUSCLE FIBER;

ANIMALS; ANTIOXIDANTS; BINDING SITES; CAROTENOIDS; CELL MOVEMENT; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; HUMANS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PLATELET-DERIVED GROWTH FACTOR; PROTEIN BINDING; RATS; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 77953231676     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-010-0501-1     Document Type: Article

References (32)

1. M Andersson A Ostman J Kreysing G Backstrom PM Van de CH Heldin 1995 Involvement of loop 2 of platelet-derived growth factor-AA and -BB in receptor binding Growth Factors 12 159 164 10.3109/08977199509028962 1:STN:280: DyaK287hsFKhsg%3D%3D 8679250
2. G Britton 1995 Structure and properties of carotenoids in relation to function FASEB J 9 1551 1558 1:CAS:528:DyaK28XhsVCksw%3D%3D 8529834
3. YT Chiu CP Chiu JT Chien GH Ho J Yang BH Chen 2007 Encapsulation of lycopene extract from tomato pulp waste with gelatin and poly (gamma-glutamic acid) as carrier J Agric Food Chem 55 5123 5130 10.1021/jf0700069 1:CAS:528:DC%2BD2sXlvFKjtLg%3D 17542604 (Pubitemid 47056067)
4. J Dong J Grunstein M Tejada F Peale G Frantz WC Liang W Bai L Yu J Kowalski X Liang G Fuh HP Gerber N Ferrara 2004 VEGF-null cells require PDGFR alpha signaling-mediated stromal fibroblast recruitment for tumorigenesis EMBO J 23 2800 2810 10.1038/sj.emboj.7600289 1:CAS:528:DC%2BD2cXlvValtrY%3D 15229650 (Pubitemid 39013552)
5. A El Agamey GM Lowe DJ McGarvey A Mortensen DM Phillip TG Truscott AJ Young 2004 Carotenoid radical chemistry and antioxidant/pro-oxidant properties Arch Biochem Biophys 430 37 48 10.1016/j.abb.2004.03.007 1:CAS:528: DC%2BD2cXmvFeltr0%3D 15325910 (Pubitemid 39119778)
6. T Fiaschi P Chiarugi F Buricchi E Giannoni ML Taddei D Talini G Cozzi S Zecchi-Orlandini G Raugei G Ramponi 2001 Low molecular weight protein-tyrosine phosphatase is involved in growth inhibition during cell differentiation J Biol Chem 276 49156 49163 10.1074/jbc.M107538200 1:CAS:528:DC%2BD38XktlemtA%3D%3D 11595742
7. E Giovannucci A Ascherio EB Rimm MJ Stampfer GA Colditz WC Willett 1995 Intake of carotenoids and retino in relation to risk of prostate cancer J Natl Cancer Inst 87 1767 1776 10.1093/jnci/87.23.1767 1:CAS:528:DyaK28XktlGntA%3D%3D 7473833
8. D Heber QY Lu 2002 Overview of mechanisms of action of lycopene Exp Biol Med 227 920 923 1:CAS:528:DC%2BD38Xos1ynsro%3D
9. CH Heldin B Westermark 1999 Mechanism of action and in vivo role of platelet-derived growth factor Physiol Rev 79 1283 1316 1:CAS:528: DyaK1MXmvVymtLY%3D 10508235
10. CH Heldin A Ostman L Ronnstrand 1998 Signal transduction via platelet-derived growth factor receptors Biochimica et Biophysica Acta (BBA) - reviews on cancer 1378 F79 F113 10.1016/S0304-419X(98)00015-8 1:CAS:528:DyaK1cXkvFOnu74%3D (Pubitemid 28381127)
11. AD Hughes GF Clunn J Refson C Moliou-Mason 1996 Platelet-derived growth factor (PDGF): actions and mechanisms in vascular smooth muscle Gen Pharmacol: Vasc Sys 27 1079 1089 10.1016/S0306-3623(96)00060-2 1:CAS:528:DyaK28XntFWrtL4%3D (Pubitemid 26375419)
12. C-F Hung C-L Fang M-H Liao J-Y Fang 2007 The effect of oil components on the physicochemical properties and drug delivery of emulsions: tocol emulsion versus lipid emulsion Int J Pharm 335 193 202 10.1016/j.ijpharm.2006.11.016 1:CAS:528:DC%2BD2sXjs1Cnsbc%3D 17129692 (Pubitemid 46505069)
13. AV Jones NC Cross 2004 Oncogenic derivatives of platelet-derived growth factor receptors Cell Mol Life Sci 61 2912 2923 10.1007/s00018-004-4272-z 1:CAS:528:DC%2BD2MXot1agsA%3D%3D 15583853 (Pubitemid 40104589)
14. JH Kim YR Jin BS Park TJ Kim SY Kim Y Lim JT Hong HS Yoo YP Yun 2005 Luteolin prevents PDGF-BB-induced proliferation of vascular smooth muscle cells by inhibition of PDGF beta-receptor phosphorylation Biochem Pharmacol 69 1715 1721 10.1016/j.bcp.2005.04.002 1:CAS:528:DC%2BD2MXltVOns74%3D 15935146 (Pubitemid 40780071)
15. M Kovalenko L Ronnstrand CH Heldin M Loubtchenkov A Gazit A Levitzki FD Bohmer 1997 Phosphorylation site-specific inhibition of platelet-derived growth factor beta-receptor autophosphorylation by the receptor blocking tyrphostin AG1296 Biochemistry 36 6260 6269 10.1021/bi962553l 1:CAS:528:DyaK2sXivF2ntr8%3D 9174341 (Pubitemid 27231382)
16. J Kreysing A Ostman PM van de Canoy G Backstrom CH Heldin 1996 Identification of three amino acid residues in the B-chain of platelet-derived growth factor with different importance for binding to PDGF alpha- and beta-receptors FEBS Lett 385 181 184 10.1016/0014-5793(96)00349-3 1:CAS:528:DyaK28XivFOhsrg%3D 8647246 (Pubitemid 26167454)
17. G Li K Satyamoorthy F Meier C Berking T Bogenrieder M Herlyn 2003 Function and regulation of melanoma-stromal fibroblast interactions: when seeds meet soil Oncogene 22 3162 3171 10.1038/sj.onc.1206455 1:CAS:528: DC%2BD3sXkt12qurs%3D 12789292 (Pubitemid 36713768)
18. HM Lo CF Hung YL Tseng BH Chen JS Jian WB Wu 2007 Lycopene binds PDGF-BB and inhibits PDGF-BB-induced intracellular signaling transduction pathway in rat smooth muscle cells Biochem Pharmacol 74 54 63 10.1016/j.bcp.2007.03.017 1:CAS:528:DC%2BD2sXlvV2qtbc%3D 17449016 (Pubitemid 46802489)
19. MW Majesky MA Reidy DF Bowen-Pope CE Hart JN Wilcox SM Schwartz 1990 PDGF ligand and receptor gene expression during repair of arterial injury J Cell Biol 111 2149 2158 10.1083/jcb.111.5.2149 1:CAS:528:DyaK3cXlvV2ju7w%3D 2172262
20. C Oefner A D'Arcy FK Winkler B Eggimann M Hosang 1992 Crystal structure of human platelet-derived growth factor BB EMBO J 11 3921 3926 1:CAS:528:DyaK38Xmt1Knurc%3D 1396586
21. AR Osornio-Vargas PM Lindroos PG Coin A Badgett NA Hernandez-Rodriguez JC Bonner 1996 Maximal PDGF-induced lung fibroblast chemotaxis requires PDGF receptor-alpha Am J Physiol Lung Cell Mol Physiol 271 L93 L99 1:CAS:528:DyaK28XkslynsLo%3D
22. K Pietras T Sjoblom K Rubin CH Heldin A Ostman 2003 PDGF receptors as cancer drug targets Cancer Cell 3 439 443 10.1016/S1535-6108(03)00089-8 1:CAS:528:DC%2BD3sXktlyiurY%3D 12781361 (Pubitemid 38340290)
23. EW Raines 2004 PDGF and cardiovascular disease Cytokine Growth Factor Rev 15 237 254 10.1016/j.cytogfr.2004.03.004 1:CAS:528:DC%2BD2cXltVKhtL4%3D 15207815 (Pubitemid 38781049)
24. LJ Reigstad JE Varhaug JR Lillehaug 2005 Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family FEBS J 272 5723 5741 10.1111/j.1742-4658.2005.04989.x 1:CAS:528:DC%2BD2MXht1Kgu73O 16279938 (Pubitemid 41689346)
25. T Rissanen S Voutilainen K Nyyssonen R Salonen JT Salonen 2000 Low plasma lycopene concentration is associated with increased intima-media thickness of the carotid artery wall Arterioscler Thromb Vasc Biol 20 2677 2681 1:CAS:528:DC%2BD3MXitlWhuw%3D%3D 11116071
26. TH Rissanen S Voutilainen K Nyyssonen R Salonen GA Kaplan JT Salonen 2003 Serum lycopene concentrations and carotid atherosclerosis: the Kuopio Ischaemic Heart Disease Risk Factor Study Am J Clin Nutr 77 133 138 1:CAS:528: DC%2BD3sXhtFyntw%3D%3D 12499332
27. M Sjolund U Hedin T Sejersen CH Heldin J Thyberg 1988 Arterial smooth muscle cells express platelet-derived growth factor (PDGF) A chain mRNA, secrete a PDGF-like mitogen, and bind exogenous PDGF in a phenotype- and growth state-dependent manner J Cell Biol 106 403 413 10.1083/jcb.106.2.403 1:STN:280:DyaL1c7hsFGqsg%3D%3D 2828383
28. M Sundaresan ZX Yu VJ Ferrans K Irani T Finkel 1995 Requirement for generation of H2O2 for platelet-derived growth factor signal transduction Science 270 296 299 10.1126/science.270.5234.296 1:CAS:528:DyaK2MXoslehs7c%3D 7569979
29. M Tallquist A Kazlauskas 2004 PDGF signaling in cells and mice Cytokine Growth Factor Rev 15 205 213 10.1016/j.cytogfr.2004.03.003 1:CAS:528: DC%2BD2cXltVKht7k%3D 15207812 (Pubitemid 38781046)
30. B Venkatesan N Ghosh-Choudhury F Das L Mahimainathan A Kamat BS Kasinath HE Abboud GG Choudhury 2008 Resveratrol inhibits PDGF receptor mitogenic signaling in mesangial cells: role of PTP1B FASEB J 22 3469 3482 10.1096/fj.08-109488 1:CAS:528:DC%2BD1cXht1SqsrnJ 18567737
31. AA Weber T Neuhaus RA Skach J Hescheler HY Ahn K Schror Y Ko A Sachinidis 2003 Mechanisms of the inhibitory effects of epigallocatechin-3 gallate on platelet-derived growth factor-BB-induced cell signaling and mitogenesis FASEB J 18 128 130 14630705
32. JC Yu MA Heidaran JH Pierce JS Gutkind D Lombardi M Ruggiero SA Aaronson 1991 Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction Mol Cell Biol 11 3780 3785 1:CAS:528:DyaK3MXks1Kjs7o%3D 1646396