Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells

Blood

Volumn 118, Issue 13, 2011, Pages 3538-3548

  Wehrens, Ellen J ^a   Mijnheer, Gerdien ^a   Duurland, Chantal L ^a   Klein, Mark ^a   Meerding, Jenny ^a   Van Loosdregt, Jorg ^a   De Jager, Wilco ^a   Sawitzki, Birgit ^b,c   Coffer, Paul J ^a   Vastert, Bas ^a   Prakken, Berent J ^a   Van Wijk, Femke ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b Institute of Medical Immunology   (Germany)

^c Berlin Brandenburg Center for Regenerative Therapies   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 5; INTERLEUKIN 6; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; ARTICLE; AUTOIMMUNE DISEASE; BLOOD; CELL CULTURE; CELL PROLIFERATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; JUVENILE RHEUMATOID ARTHRITIS; LYMPHOCYTE FUNCTION; MALE; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SCHOOL CHILD;

EID: 80053365569     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-12-328187     Document Type: Article

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