Shizukaol D Isolated from Chloranthus japonicas Inhibits AMPK-Dependent Lipid Content in Hepatic Cells by Inducing Mitochondrial Dysfunction

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Hu, Rongkuan ^a   Yan, Huan ^b   Hao, Xiaojiang ^b   Liu, Haiyang ^b   Wu, Jiarui ^a,c,d  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b KUNMING INSTITUTE OF BOTANY   (China)

^c INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^d SHANGHAI ADVANCED RESEARCH INSTITUTE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIPID; METFORMIN; PLANT MEDICINAL PRODUCT; SHIZUKAOL D; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ARTICLE; CHLORANTHUS JAPONICUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; ENERGY METABOLISM; ENZYME ACTIVATION; LIVER CELL; LIVER MITOCHONDRION; MEDICINAL PLANT; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; SIGNAL TRANSDUCTION;

ACETYL-COA CARBOXYLASE; ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; AMP-ACTIVATED PROTEIN KINASES; CELL RESPIRATION; ENZYME ACTIVATION; HEP G2 CELLS; HUMANS; LIPID METABOLISM; LIVER; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; PHOSPHORYLATION; PLANT EXTRACTS; SIGNAL TRANSDUCTION; TRACHEOBIONTA; TRITERPENES;

EID: 84881489744     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0073527     Document Type: Article

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