Sesquiterpene furan compound CJ-01, a novel chitin synthase 2 inhibitor from Chloranthus japonicus Sieb.

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 5, 2008, Pages 1041-1044

  Yim, Nam Hui ^a   Hwang, Eui Il ^b   Yun, Bong Sik ^a   Park, Ki Duk ^a   Moon, Jae Sun ^a   Lee, Sang Han ^c   Sung, Nack Do ^d   Kim, Sung Uk ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b KT and G Corporation   (South Korea)

^c Kyungpook National University   (South Korea)

^d Chungnam National University   (South Korea)

Author keywords

Antifungal activity; Chitin synthase 2 inhibitor; Chloranthus japonicus; Fungal cell wall; Sesquiterpene furan compound CJ 01

Indexed keywords

3,4,8A TRIMETHYL 4A,7,8,8A TETRAHYDRO 4A NAPHTO[2,3 B]FURAN 9 ONE; ANTIFUNGAL AGENT; CHITIN SYNTHASE 2 INHIBITOR; CJ 01; NIKKOMYCIN Z; POLYOXIN D; SESQUITERPENE DERIVATIVE;

ANTIFUNGAL ACTIVITY; ARTICLE; CHLORANTHUS JAPONICUS; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG ISOLATION; DRUG MECHANISM; DRUG SCREENING; DRUG SPECIFICITY; ENZYME ACTIVITY; ENZYME INHIBITION; FUNGAL STRAIN; MEDICINAL PLANT; NONHUMAN; SACCHAROMYCES CEREVISIAE; SPECTROSCOPY; STRUCTURE ACTIVITY RELATION;

ANIMALS; CHITIN SYNTHASE; ENZYME INHIBITORS; FUNGI; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANES; MICROBIAL SENSITIVITY TESTS; MOLECULAR CONFORMATION; MYCOSES; PLANTS; SACCHAROMYCES CEREVISIAE; SESQUITERPENES;

EID: 44349084801     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.1041     Document Type: Article

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