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Volumn 56, Issue 15, 2013, Pages 6054-6068

Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

3 [1 (2,6 DIFLUOROPHENYLAMINO) 4 METHYL 1 OXOPENTAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [1 (6 FLUOROBENZO[D]THIAZOL 2 YLAMINO) 3 (1H IMIDAZOL 4 YL) 1 OXOPROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [1 [4 (4 ETHYNLPHENYL)THIAZOL 2 YLAMINO] 1 OXO 3 (THIAZOL 4 YL)PROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [1 [4 (4 FLUOROPHENYL)THIAZOL 2 YLAMINO] 1 OXO 3 (THIAZOL 4 YL)PROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [1 [4 (4 FLUOROPHENYL)THIAZOL 2 YLAMINO] 3 (1 METHYL 1H IMIDAZOL 4 YL) 1 OXOPROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [1 [4 (4 FLUOROPHENYL)THIAZOL 2 YLAMINO] 3 (1H IMIDAZOL 4 YL) 1 OXOPENTAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [1 [4 (4 FLUOROPHENYL)THIAZOL 2 YLAMINO] 3 (1H IMIDAZOL 4 YL) 1 OXOPROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [1 [4 (4 FLUOROPHENYL)THIAZOL 2 YLAMINO] 3 (METHYL 1H IMIDAZOL 5 YL) 1 OXOPROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [1 [4 (4 FLUOROPHENYL)THIAZOL 2 YLAMINO] 4 METHYL 1 OXOPENTAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [1 [4 (4 FLUOROPHENYLSULFONAMIDO)BUTYLAMINO] 4 METHYL 1 OXOPENTAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [1 [4 (6 FLUOROBENZO[D])THIAZOL 2 YLAMINO] 3 (1H IMIDAZOL 4 YL) 1 OXOPROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [1 [4 [5 (1,2 DITHIOLAN 3 YL)PENTANAMIDO]BUTYLAMINO] 4 METHYL 1 OXOPENTAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [1 OXO 1 (PHENYLAMINO) 3 (THIAZOL 4-YL)PROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [1 OXO 1 (PROP 2 YNYLAMINO) 3 (THIAZOL 4YL)PROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLATE; 3 [1 OXO 1 [(1 PHENYL 1H 1,2,3 TRIAZOL 4 YL)METHYLAMINO] 3 (THIAZOL 4 YL)PROPAN 2YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [3 (1H IMIDAZOL 4 YL) 1 OXO 1 (PHENYLAMINO)PROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [3 (1H IMIDAZOL 5 YL) 1 (MESITYLAMINO) 1 OXOPROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [4 METHYL 1 OXO 1 (PHENYLAMINO)PENTAN 2YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [4 METHYL 1 OXO 1 [4 [5 [(3AS, 4S, 6AR) 2 OXOHEXAHYDRO 1H THIENO[3,4 D]IMIDAZOL 4 YL]PENTANAMIDO]BUTYLAMINO]PENTAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID; 3 [[1 OXO 1 (1 PHENYL 1H 1,2,3 TRIAZOL 4 YL)METHYLAMINO] 3 (THIAZOL 4 YL)PROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLATE; CALPASTATIN; EPOXIDE; ETHYL 3 [1 [1 (4 NITROPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHYLAMINO] 1 OXO 3 (THIAZOL 4 YL)PROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLATE; ETHYL 3 [1 [1 (BENZO[D][1,3]DIOXOL 5 YL) 1H 1,2,3 TRIAZOL 4 YL]METHYLAMINO] 1 OXO 3 (THIAZOL 4 YL)PROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLATE; ETHYL 3 [1 [1 (BROMOPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHYLAMINO] 1 OXO 3 (THIAZOL 4 YL)PROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLATE; ETHYL 3 [1 OXO 1[[1 (4 SULFAMOYLPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHYLAMINO] 3 (THIAZOL 4 YL) PROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLATE; ETHYL 3 [1 OXO 1[[1 [4 (PIPERIDIN 1 YLSULFONYL)PHENYL] 1H 1,2,3 TRIAZOL 4 YL]METHYLAMINO] 3 (THIAZOL 4 YL) PROPAN 2 YLCARBAMOYL]OXIRANE 2 CARBOXYLATE; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; PEPTIDOMIMETIC AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84881466563     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm4006719     Document Type: Article
Times cited : (29)

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