New peptidic cysteine protease inhibitors derived from the electrophilic α-amino acid aziridine-2,3-dicarboxylic acid

Journal of Medicinal Chemistry

Volumn 42, Issue 4, 1999, Pages 560-572

  Schirmeister, Tanja ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO ACID; AZIRIDINE 2,3 DICARBOXYLIC ACID; CYSTEINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INACTIVATION; ENZYME SPECIFICITY; PH; REACTION TIME; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION;

AZIRIDINES; CATHEPSIN B; CATHEPSINS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; ENDOPEPTIDASES; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; PAPAIN; PEPTIDES; PROTEIN CONFORMATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033602268     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm981061z     Document Type: Article

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