Pycnogenol® and Antioxidant Activity in Health Promotion

Bioactive Food as Interventions for Arthritis and Related Inflammatory Diseases

Volumn , Issue , 2013, Pages 405-411

  Chowdhury, Z T ^a   Watson, R R ^a,b  

^a UNIVERSITY OF ARIZONA   (United States)

^b Southwest Scientific Editing and Consulting   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84881276279     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-397156-2.00029-6     Document Type: Chapter

References (30)

1. Bayeta E., Lau B.H.S. Pycnogenol inhibits generation of inflammatory mediators in macrophages. Nutrition Research 2000, 20:249-259.
2. Berryman A.M., Maritim A.C., Sanders R.A., Watkins J.B. Influence of treatment of diabetic rats with combinations of Pycnogenol, β-carotene, and α-lipoic acid on parameters of oxidative stress. Journal of Biochemical and Molecular Toxicology 2004, 18:345-352.
3. Chappey O., Dosquet C., Wautier M.-P., Wautier J.-L. Advanced glycation end-products, oxidant stress and vascular lesions. European Journal of Clinical Investigation 1997, 27:97-108.
4. Chida M., Suzuki K., Nakanishi-Ueda T., et al. In vitro testing of antioxidants and biochemical end-points in bovine retinal tissue. Ophthalmic Research 1999, 31:407-415.
5. Choo K.J., Yun C.H., Yoon D.O., et al. Effect of bioflavonoids extracted from the bark of Pinus maritima on proinflammatory cytokine interleukin-1 production in lipopolysaccharide-stimulated raw 264.7. Toxicology and Applied Pharmacology 2000, 168:64-71.
6. Chovanova Z., Muchova J., Sivonova M., et al. Effect of polyphenolic extract, Pycnogenol®, on the level of 8-oxoguanine in children suffering from attention deficit/hyperactivity disorder. Free Radical Research 2006, 40:1003-1010.
7. Cossins E., Lee R., Packer L. ESR studies of vitamin C regeneration, order of reactivity of natural source phytochemical preparations. Biochemistry and Molecular Biology International 1998, 45:583-598.
8. Crawford T.N., Alfaro D.V., Kerrison J.B., Jablon E.P. Diabetic retinopathy and angiogenesis. Current Diabetes Reviews 2009, 5:8-13.
9. Dene B.A., Maritim A.C., Sanders R.A., Watkins J.B. Effects of antioxidant treatments on normal and diabetic rat retinal enzyme activities. Journal of Ocular Pharmacology and Therapeutics 2005, 21:28-35.
10. Devaraj S., Vega-Lopez S., Kaul N., et al. Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profile. Lipids 2002, 37:931-934.
11. Dvorakova M., Sivonova M., Trebaticka J., et al. The effect of polyphenolic extract from pine bark, Pycnogenol®, on the level of glutathione in children suffering from attention deficit hyperactivity disorder (ADHD). Redox Report 2006, 11:163-172.
12. Gulati O. The nutraceutical Pycnogenol: its role in cardiovascular health and blood glucose control. Biomedical Reviews 2005, 16:49-57.
13. Kim J., Chehade J., Pinnas J., Mooradian A.D. Effect of select antioxidants on malondialdehyde modification of proteins. Nutrition 2000, 16:1079-1081.
14. Krumhout D. Epidemiology of cardiovascular diseases in Europe. Public Health Nutrition 2001, 4:441-457.
15. Maritim A., Dene B.A., Sanders R.A., Watkins J.B. Effects of Pycnogenol treatment on oxidative stress in streptozotocin-induced diabetic rats. Journal of Biochemical and Molecular Toxicology 2003, 17:193-199.
16. Nakanishi-Ueda T., Kamegawa M., Ishigaki S., et al. Inhibitory effect of lutein and Pycnogenol on lipid peroxidation in porcine retinal homogenate. Journal of Clinical Biochemistry and Nutrition 2006, 38:204-210.
17. Nishioka K., Hidaka T., Nakamura S., et al. Pycnogenol®, french maritime pine bark extract, augments endothelium-dependent vasodilation in humans. Hypertension Research 2007, 30:775-780.
18. Packer L. Free radical scavengers and antioxidants in prophylaxy and treatment of brain diseases. Free Radicals in the Brain 1992, Springer-Verlag, New York. L. Packer, L. Prilipko, Y. Christen (Eds.).
19. Packer L., Rimbach G., Virgili F. Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritima) bark, Pycnogenol®. Free Radical Biology & Medicine 1999, 27:704-724.
20. Ramos F.M.M., Schonlau F., Novaes P.D., et al. Pycnogenol® protects against ionizing radiation as shown in the intestinal mucosa of rats exposed to x-rays. Phytotherapy Research 2006, 20:676-679.
21. Rice-Evans C.A., Miller N.J., Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radical Biology & Medicine 1996, 20:933-956.
22. Rohdewald P. Pycnogenol®, French maritime pine bark extract. Encyclopedia of Dietary Supplements 2005, 545-553. Marcel Dekker, New York.
23. Ryan J., Croft K., Mori T., et al. An examination of the effects of the antioxidant Pycnogenol® on cognitive performance, serum lipid profile, endocrinological and oxidative stress biomarkers in an elderly population. Journal of Psychopharmacology 2008, 22:553-562.
24. Sharma S.C., Sharma S., Gulati O.P. Pycnogenol inhibits the release of histamine from mast cells. Phytotherapy Research 2003, 1:66-69.
25. Sharma S.C., Sharma S., Gulati O.P. Pycnogenol prevent haemolytic injury in G6PD deficient human erythrocytes. Phytotherapy Research 2003, 17:671-674.
26. Shuguang L., Xinwen Z., Sihong X., Gulati O.P. Role of Pycnogenol® in aging by increasing the Drosophila's life-span. European Bulletin of Drug Research 2003, 11:39-45.
27. Sivonova M., Waczulikova I., Kilanczyk E., et al. The effect of Pycnogenol® on the erythrocyte membrane fluidity. General Physiology and Biophysics 2004, 23:39-51.
28. Spadea L., Balestrazzi E. Treatment of vascular retinopathies with Pycnogenol®. Phytotherapy Research 2001, 15:219-233.
29. Veurink G., Liu D., Taddei K., et al. Reduction of inclusion body pathology in ApoE-deficient mice fed a combination of antioxidants. Free Radical Biology & Medicine 2003, 34:1070-1077.
30. Voss P., Horakova L., Jakstadt M., Kiekebusch D., Grune T. Ferritin oxidation and proteasomal degradation: protection by antioxidants. Free Radical Research 2006, 40:673-683.