Inhibitory effect of lutein and pycnogenol on lipid peroxidation in porcine retinal homogenate

Journal of Clinical Biochemistry and Nutrition

Volumn 38, Issue 3, 2006, Pages 204-210

  Nakanishi Ueda, Takako ^a   Kamegawa, Maki ^a   Ishigaki, Seiichiro ^a   Tsukahara, Masahiko ^a   Yano, Satoshi ^a   Wada, Katsuya ^b   Yasuhara, Hajime ^a  

^a SHOWA UNIVERSITY   (Japan)

^b Naturally Plus Co Ltd   (Japan)

Author keywords

Lipid peroxide; Lutein; Pycnogenol; Retina

Indexed keywords

2,2' AZOBIS(2 AMIDINOPROPANE); 2,2' AZOBIS(2,4 DIMETHYLVALERONITRILE); FERRIC CHLORIDE; FLAVONOID; LIPID HYDROPEROXIDE; PYCNOGENOL; THIOBARBITURIC ACID REACTIVE SUBSTANCE; VISUAL PIGMENT; XANTHOPHYLL;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG INHIBITION; DRUG POTENTIATION; HOMOGENATE; HYDROPHILICITY; IC 50; LIPID PEROXIDATION; LIPOPHILICITY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; RETINA MACULA LUTEA; SWINE;

SUIDAE;

EID: 33646780277     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.38.204     Document Type: Article

References (47)

1. Ohia, S.E., Opere, C.A., and Leday, A.M.: Pharmacological consequences of oxidative stress in ocular tissues. Mutat. Res., 579, 22-36, 2005.
2. Osawa, T. and Kato, Y.: Protective role of antioxidative food factors in oxidative stress caused by hyperglycemia. Ann. N.Y. Acad. Sci., 1043, 440-451, 2005.
3. Beatty, S., Koh, H., Phil, M., Henson, D., and Boulton, M.: The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv. Ophthalmol., 45, 115-134, 2000.
4. Dani, C., Cecchi, A., and Bertini, G.: Role of oxidative stress as physiopathologic factor in the preterm infant. Minerva. Pediatr., 56, 381-394, 2004.
5. Armstrong, D., Abdella, N., Salman, A., Miller, N., Abdel-Rahman, E., and Bojancyzk, M.: Relationship of lipid peroxides to diabetic complications: comparison with conventional laboratory tests. J. Diab. Compl., 6, 116-122, 1992.
6. Alder, V.A., Su, Er-Ning., Dao-Yi, Yu., Cringle, S.J., and Paula-K, Y.: Diabetic retinopathy: Early functional changes. Clin. Exp. Pharmacol. Physiol., 24, 758-788, 1997.
7. Tanaka, Y.: Peroxidative reactions in the vitreous as related to diabetic retinopathy. J. Jpn. Ophthalmol. Soc., 102, 576-582, 1998.
8. Verdejo, C., Marco, P., Renau-Piqueras, J., and Pinazo-Duran, M.D.: Lipid peroxidation in proliferative vitreoretinopathies. Eye, 13, 183-188, 1999.
9. Spaide, R.F., Ho-Spaide, W.C., Browne, W.R., and Armstrong, D.: Characterization of peroxidized lipids in Bruch's membrane. Retina, 19, 141-147, 1999.
10. Berman, E.R.: Lipid peroxdation, free radicals, light damage, and protective mechanisms, in Biochemistry of the eye. ed. By Berman, E.R., New York and London, Plenum Press, pp. 362-370, 1991.
11. Burton, G.W. and Ingold, K.U.: Beta-Carotene: an unusual type of lipid antioxidant. Science, 224, 569-573, 1984.
12. Edge, R., McGarvey, D.J., and Truscott, T.G.: The carotenoids as anti-oxidants-a review. J. Photochem. Photobiol. B: Biol., 41, 189-200, 1997.
13. Chopra, M., Willson, R.L., and Thurnham, D.I.: Free radical scavenging of lutein in vitro. Ann. N. Y. Acad. Sci., 691, 246-249, 1993.
14. Santosa, S. and Jones, P.J.H.: Oxidative stress in ocular disease: Does lutein play a protective role? CMAJ, 173, 861-862, 2005.
15. Drehsen, G.: From ancient pine bark uses to Pycnogenol. in Antioxidant food supplements in human health, eds. By Packer, L., Hiramatsu, M., and Yoshikawa, T., Academic Press, New York, pp. 311-322, 1999.
16. Packer, L., Rimbach, G., and Virgili, F.: Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritime) bark, Pycnogenol. Free Radic. Biol. Med., 27, 704-724, 1999.
17. Virgili, F., Kim, D., and Packer, L.: Procyanidins extracted from pine bark protect alpha-tocopherol in ECV 304 endothelial cells challenged by activated RAW 264. 7 macrophages: role of nitric oxide and peroxynitrite. FEBS Lett., 431, 315-318, 1998.
18. Virgili, F., Kobuchi, H., and Packer, L.: Procyanidins extracted from Pinus maritime (Pycnogenol): scavengers of free radical species and modulators of nitrogen monoxide metabolism in activated murine RAW 264. 7 macrophages. Free Radic. Biol. Med., 24, 1120-1129, 1998.
19. Guo, Q., Zhao, B., and Packer, L.: Electron spin resonance study of free radicals formed from a procyanidin-rich pine (Pinus maritime) bark extract, Pycnogenol. Free Radic. Biol. Med., 27, 1308-1312, 1999.
20. Bates-Smith, E.C.: Phytochemistry of proanthocyanidins. Phytochemistry, 14, 1107-1113, 1975.
21. Cheynier, V., Souquet, J-M., Le Roux, E., Guyrot, S., and Rigaud, J.: Size separation of condensed tannins by normal phase high performance liquid chromatography. Methods Enzymol., 299, 178-184, 1998.
22. Ueda, T., Ueda, T., and Armstrong, D.: Preventive effect of natural and synthetic antioxidants on lipid peroxidation in the mammalian eye. Ophthalmic. Res., 28, 184-192, 1996.
23. Chida, M., Suzuki, K., Nakanishi-Ueda, T., Ueda, T., Yasuhara, H., Koide, R., and Armstrong, D.: In vitro testing of antioxidants and biochemical end-points in bovine retinal tissue. Ophthalmic Res., 31, 407-415, 1999.
24. Hiramitsu, T. and Armstrong, D.: Preventive effect of antioxidants on lipid peroxidation in the retina. Ophthlmic Res., 23, 196-203, 1991.
25. Suzuki, K., Ueda, T., Nakanishi-Ueda, T., Yamamoto, Y., Chida, M., Matsuishi, M., Kan, K., Higa, A., Armstrong, D., Yasuhara, H., and Koide, R.: Effect of antioxidants on radical-initiated peroxidation of retinal homogenate. J. Jpn. Ophthalmol. Soc., 104, 466-470, 2000.
26. Ohkawa, H., Ohishi, N., and Yagi, K.: Assay for lipid peroxide in animal tissues by thiobarbituric acid reaction. Anal. Biochem., 95, 351-358, 1979.
27. Lowry, O., Rosebrough, N.J., Farr, A.L., and Randall, R.J.: Protein measurement with the folin phenol reagent. J. Bio. Chem., 193, 265-275, 1951.
28. Niki, E.: Free radical initiators as source of water- or lipid-soluble peroxyl radicals, in Methods in Enzymology, eds. By Packer, L. and Glazer, A.N., Academic Press, New York, vol. 186, pp. 100-108, 1990.
29. Blazso, G., Gabor, M., Sibbel, R., and Rohdewald, P.: Antiinflamatry and superoxide radical scavenging activities of procyanidins containing extract from the bark of Pinus pinaster Sol. and its fractions. Pharm. Pharmacol., 3, 217-220, 1994.
30. Noda, Y., Anzai, K., Mori, A., Kohno, M., Shinmei, M., and Packer L.: Hydroxyl and superoxide anion radical scavenging activities of natural source antioxidants using the computerized JES-FR30 ESR spectrometer system. Biochm. Mol. Biol. Int., 42, 35-44, 1997.
31. Gale, C.R., Hall, N.F, Phillips, D.W., and Martyn, C.N.: Lutein and zeaxanthin status and risk of age-related macular degeneration. Invest. Ophthalmol. Vis. Sci., 44, 2461-2465, 2003.
32. Bone, R.A., Landrum, J.T., Guerra, L.H., and Ruiz, C.A.: Lutein and zeaxanthin dietary density and serum concentrations of these carotenoids in humans. J. Nutr., 133, 992-998, 2003.
33. Rapp, L.M., Maple, S.S., and Choi, J.H.: Lutein and zeaxanthin concetrations in rod outer segments membranes from perifoveal and peripheral human retina. Invest. Ophthalmol. Vis. Sci., 41, 1200-1209, 2004.
34. Virgili, F., Pagana, G., Bourne, L., Rimbach, G., Natella, F., Rice-Evans, C., and Packer, L.: Ferulic acid excretion as a marker of consumption of a French maritime pine (Pinus Maritima) bark extract. Free Radical. Biol. Med., 28, 1249-1256, 2000.
35. Saliou, C., Rimbach, G., Moini, H., McLaughlin, L., Hosseini, S., Lee, J., Watson, R.R., and Packer, L.: Solar ultraviolet-induced erythema in human skin and nuclear factor-kappa-B-dependent gene expression in kerationcytes are modulated by a French maritime pine bark extract. Free Radical. Biol. Med., 30, 154-160, 2001.
36. Devaraj, S., Vega-Lopez, S., Kaul, N., Schonlau, F., Rphdewld, P., and Jialal, I.: Supplementation with a pine bark extract rich in polyphenols increses plasma antioxidant capacity and alters the plasma lipoprotein profile. Lipids, 37, 931-934, 2002.
37. Mozaffarieh, M., Sacu, S., and Wedrich, A.: The role of the carotenoids, lutein and zeaxanthin, in protecting against age-related macula degeneration: A review based on controversial evidence. Nutr. J., 2, 20-28, 2003.
38. Richer, S., Stiles, W., Statkute, L., Pulido, J., Frankowski, J., Rudy, D., Pei, K., Tsipursky, M., and Nyland, J.: Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Suplementation Trial). Optometry, 75, 216-230, 2004.
39. Ribaya-Mercado, J.D. and Blumberg, J.B.: Lutein and zeaxanthin and their potential roles in disease prevention. J. Am. Coll. Nutr., 23, 567S-587S, 2004.
40. Dasch, B., Fuhs, A., Schmidt, J., Behrens, T., Meister, A., Wellmann, J., Fobker, M., Pauleikhoff, D., and Hense, H.W.: Serum levels of macular carotenoids in relation to age-related maculopathy: The Muenster Aging and Retina Study (MARS). Graefes Arch. Clin. Exp. Ophthalmol., 243, 1028-1035, 2005.
41. Schmidt-Erfurth, U.: Nutrition and retina. Dev. Ophthalmol., 38, 120-147, 2005.
42. Nielsen, J., Naash, M.I., and Anderson, R.E.: The regional distribution of vitamins E and C in mature and premature human retinas. Invest. Ophthalmol. Vis. Sci., 29, 22-26, 1987.
43. Winkler, R.S. and Giblin, F.J.: Glutathione oxidation in retina: Effects on biochemical and electrical activities. Exp. Eye Res., 36, 287-297, 1983.
44. Cossins, E., Lee, R., and Packer, L.: ESR studies of vitamin C regeneration, order of reactivity of natural source phytochemical preparerions. Biochem. Mol. Biol. Int., 45, 583-597, 1998.
45. Wei, Z.H., Peng, Q., and Lau, B.H.S.: Pycnogenol enhances endothelial cell antioxidant defenses. Redox. Rep., 3, 219-224, 1997.
46. Siler-Marsiglio, K.I., Paiva, M., Madorsky, I., Serrano, Y., Neeley, A., and Heaton, M.B.: Protectiv mechanisms of pycnogenol in ethanol-insulted cerebellar granule cells. J. Neurobiol., 61, 267-276, 2004.
47. Grimm, T., Schafer, A., and Hogger, P.: Antioxidant activity and inhibition of matrix metalloproteinases by metabolites of maritime pine bark extract (pycnogenol). Free Radical. Biol. Med., 36, 811-822, 2004.