-
1
-
-
1942466518
-
p27 Kip1 modulates cell migration through the regulation of RhoA activation
-
Besson A, Gurian-West M, Schmidt A, Hall A, Roberts JM. 2004. p27 Kip1 modulates cell migration through the regulation of RhoA activation. Gene Dev 18:862-876.
-
(2004)
Gene Dev
, vol.18
, pp. 862-876
-
-
Besson, A.1
Gurian-West, M.2
Schmidt, A.3
Hall, A.4
Roberts, J.M.5
-
2
-
-
21844450693
-
Involvement of microtubule and Rho pathway in TGF-β1-induced lung vascular barrier dysfunction
-
Birukova AA, Birkov K, Adyshev D, Usatyuk P, Natarajan V, Garcia JGN, Verin AD. 2005. Involvement of microtubule and Rho pathway in TGF-β1-induced lung vascular barrier dysfunction. J Cell Physiol 204:934-947.
-
(2005)
J Cell Physiol
, vol.204
, pp. 934-947
-
-
Birukova, A.A.1
Birkov, K.2
Adyshev, D.3
Usatyuk, P.4
Natarajan, V.5
Garcia, J.G.N.6
Verin, A.D.7
-
3
-
-
70349335654
-
Control of cell adhesion dynamics by Rap1 signaling
-
Boettner B, Van Aelst L. 2009. Control of cell adhesion dynamics by Rap1 signaling. Curr Opin Cell Biol 21:684-693.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 684-693
-
-
Boettner, B.1
Van Aelst, L.2
-
4
-
-
15044359236
-
Linking Rap to cell adhesion
-
Bos JL. 2005. Linking Rap to cell adhesion. Curr Opn Cell Biol 17:123-128.
-
(2005)
Curr Opn Cell Biol
, vol.17
, pp. 123-128
-
-
Bos, J.L.1
-
5
-
-
0037323858
-
The role of Rap1 in integrin-mediated cell adhesion
-
Bos JL, de Bruyn K, Enserink J, Kuiperij B, Rangarajan S, Rehmann H, Riedl J, de Rooij J, van Mansfeld F, Zwartkruis F. 2003. The role of Rap1 in integrin-mediated cell adhesion. Biochem Soc Trans 31:83-86.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 83-86
-
-
Bos, J.L.1
de Bruyn, K.2
Enserink, J.3
Kuiperij, B.4
Rangarajan, S.5
Rehmann, H.6
Riedl, J.7
de Rooij, J.8
van Mansfeld, F.9
Zwartkruis, F.10
-
6
-
-
0032480888
-
Epac is a Rap guanine-nucleotide-exchange factor directly activated by cyclic AMP
-
De Rooij J, Zwartkruis FJ, Verheijen MH, Cool RH, Nijman SM, Wittinghofer A, Bos JL. 1998. Epac is a Rap guanine-nucleotide-exchange factor directly activated by cyclic AMP. Nature 396:474-477.
-
(1998)
Nature
, vol.396
, pp. 474-477
-
-
De Rooij, J.1
Zwartkruis, F.J.2
Verheijen, M.H.3
Cool, R.H.4
Nijman, S.M.5
Wittinghofer, A.6
Bos, J.L.7
-
7
-
-
21744432683
-
GDIs: Central regulatory molecules in Rho GTPase activation
-
Der Mardirossian C, Bokoch GM. 2005. GDIs: Central regulatory molecules in Rho GTPase activation. Trends Cell Biol 15:356-363.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 356-363
-
-
Der Mardirossian, C.1
Bokoch, G.M.2
-
8
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-β family signaling
-
Derynck R, Zhang YE. 2003. Smad-dependent and Smad-independent pathways in TGF-β family signaling. Nature 425:577-584.
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
9
-
-
70350464182
-
Phosphorylation-induced conformational changes in Rap1b: Allosteric effects on switch domains and effector loop
-
Edreira M, Li S, Hochbaum D, Wong S, Gorfe AA, Ribeiro-Neto F, Woods VL, Jr., Altschuler DL. 2009. Phosphorylation-induced conformational changes in Rap1b: Allosteric effects on switch domains and effector loop. J Biol Chem 284:27480-27486.
-
(2009)
J Biol Chem
, vol.284
, pp. 27480-27486
-
-
Edreira, M.1
Li, S.2
Hochbaum, D.3
Wong, S.4
Gorfe, A.A.5
Ribeiro-Neto, F.6
Woods Jr, V.L.7
Altschuler, D.L.8
-
10
-
-
33745501378
-
p120 Catenin regulates dendritic spine and synapse development through Rho-family GTPases and cadherins
-
Ella LP, Yamato M, Zang K, Reichardt LF. 2006. p120 Catenin regulates dendritic spine and synapse development through Rho-family GTPases and cadherins. Neuron 51:43-56.
-
(2006)
Neuron
, vol.51
, pp. 43-56
-
-
Ella, L.P.1
Yamato, M.2
Zang, K.3
Reichardt, L.F.4
-
11
-
-
85006314494
-
A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK
-
Enserink JM, Christensen AE, de Rooij J, van Triest M, Schwede F, Genieser HG, Doskeland SO, Blank JL, Gos JL. 2002. A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK. Nat Cell Biol 4:901-906.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 901-906
-
-
Enserink, J.M.1
Christensen, A.E.2
de Rooij, J.3
van Triest, M.4
Schwede, F.5
Genieser, H.G.6
Doskeland, S.O.7
Blank, J.L.8
Gos, J.L.9
-
13
-
-
84860371902
-
Human immunodeficiency virus-1 tat activates NF-κB via physical interaction with IκB-α and p65
-
Fiume G, Vecchio E, de Laurentiis A, Trimboli F, Palmieri C, Pisano A, Falcone C, Pontoriero M, Rossi A, Scialdone A, Masci FF, Scala G, Quinto I. 2012. Human immunodeficiency virus-1 tat activates NF-κB via physical interaction with IκB-α and p65. Nucleic Acids Res 40:3548-3562.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 3548-3562
-
-
Fiume, G.1
Vecchio, E.2
de Laurentiis, A.3
Trimboli, F.4
Palmieri, C.5
Pisano, A.6
Falcone, C.7
Pontoriero, M.8
Rossi, A.9
Scialdone, A.10
Masci, F.F.11
Scala, G.12
Quinto, I.13
-
14
-
-
0029913467
-
Differential interaction of the Ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor
-
Herrmann C, Horn G, Spaargaren M, Wittinghofer A. 1996. Differential interaction of the Ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor. J Biol Chem 271:6794-6800.
-
(1996)
J Biol Chem
, vol.271
, pp. 6794-6800
-
-
Herrmann, C.1
Horn, G.2
Spaargaren, M.3
Wittinghofer, A.4
-
15
-
-
33748697413
-
Transforming growth factor-β1 regulates macrophage migration via RhoA
-
Kim JS, Kim JG, Moon MY, Jeon CY, Won HY, Kim HJ, Jeon YJ, Seo JY, Kim JI, Kim J, Lee JY, Kim PH, Park JB. 2006. Transforming growth factor-β1 regulates macrophage migration via RhoA. Blood 108:1821-1829.
-
(2006)
Blood
, vol.108
, pp. 1821-1829
-
-
Kim, J.S.1
Kim, J.G.2
Moon, M.Y.3
Jeon, C.Y.4
Won, H.Y.5
Kim, H.J.6
Jeon, Y.J.7
Seo, J.Y.8
Kim, J.I.9
Kim, J.10
Lee, J.Y.11
Kim, P.H.12
Park, J.B.13
-
16
-
-
0033386763
-
Transforming growth factor-β1 inhibits the growth of primary adult hepatocyte cultures by increasing cAMP levels
-
Kimura M, Ogihara M. 1999. Transforming growth factor-β1 inhibits the growth of primary adult hepatocyte cultures by increasing cAMP levels. Eur J Pharmacol 386:271-277.
-
(1999)
Eur J Pharmacol
, vol.386
, pp. 271-277
-
-
Kimura, M.1
Ogihara, M.2
-
17
-
-
18244392475
-
Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices
-
Krugmann S, Anderson KE, Ridley SH, Risso N, McGregor A, Coadwell J, Davidson K, Eguinoa A, Ellson CD, Lipp P, Manifava M, Ktistakis N, Painter G, Thuring JW, Cooper MA, Lim ZY, Holmes AB, Dove SK, Michell RH, Grewal A, Nazarian A, Erdjument-Bromage H, Tempst P, Stephens LR, Hawkins PT. 2002. Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. Mol Cell 9:95-108.
-
(2002)
Mol Cell
, vol.9
, pp. 95-108
-
-
Krugmann, S.1
Anderson, K.E.2
Ridley, S.H.3
Risso, N.4
McGregor, A.5
Coadwell, J.6
Davidson, K.7
Eguinoa, A.8
Ellson, C.D.9
Lipp, P.10
Manifava, M.11
Ktistakis, N.12
Painter, G.13
Thuring, J.W.14
Cooper, M.A.15
Lim, Z.Y.16
Holmes, A.B.17
Dove, S.K.18
Michell, R.H.19
Grewal, A.20
Nazarian, A.21
Erdjument-Bromage, H.22
Tempst, P.23
Stephens, L.R.24
Hawkins, P.T.25
more..
-
19
-
-
0030040750
-
Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes
-
Lang P, Gesbert F, DelespineCarmagnat M, Stancou R, Pouchelet M, Bertoglio J. 1996. Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. EMBO J 15:510-519.
-
(1996)
EMBO J
, vol.15
, pp. 510-519
-
-
Lang, P.1
Gesbert, F.2
DelespineCarmagnat, M.3
Stancou, R.4
Pouchelet, M.5
Bertoglio, J.6
-
20
-
-
33646164362
-
Transforming growth factor-β regulation of immune responses
-
Li MO, Wan YY, Sanjabi S, Robertson AKL, Flavell RA. 2006. Transforming growth factor-β regulation of immune responses. Annu Rev Immunol 24:4.1-4.48.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 41-448
-
-
Li, M.O.1
Wan, Y.Y.2
Sanjabi, S.3
Robertson, A.K.L.4
Flavell, R.A.5
-
21
-
-
33845463670
-
Eapc1-Rap1 signaling regulates monocyte adhesion and chemotaxis
-
Lorenowicz MJ, van Gils J, de Boer M, Hordijk PL, Fernandez-Boria M. 2006. Eapc1-Rap1 signaling regulates monocyte adhesion and chemotaxis. J Leukoc Biol 80:1542-1552.
-
(2006)
J Leukoc Biol
, vol.80
, pp. 1542-1552
-
-
Lorenowicz, M.J.1
van Gils, J.2
de Boer, M.3
Hordijk, P.L.4
Fernandez-Boria, M.5
-
22
-
-
33846859568
-
MCP-1 mediates TGF-β-induced angiogenesis by simulating vascular smooth muscle cell migration
-
Ma J, Wang Q, Fei T, Han JDJ, Chen YG. 2007. MCP-1 mediates TGF-β-induced angiogenesis by simulating vascular smooth muscle cell migration. Blood 109:987-994.
-
(2007)
Blood
, vol.109
, pp. 987-994
-
-
Ma, J.1
Wang, Q.2
Fei, T.3
Han, J.D.J.4
Chen, Y.G.5
-
23
-
-
62549153648
-
Phosphorylation of RapGAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology
-
McAvoy T, Zhou MM, Greengard P, Nairn AC. 2009. Phosphorylation of RapGAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology. Proc Natl Acad Sci USA 106:3531-3536.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3531-3536
-
-
McAvoy, T.1
Zhou, M.M.2
Greengard, P.3
Nairn, A.C.4
-
24
-
-
14844364701
-
Regulation of the polarity protein Par6 by TGF-β receptors controls epithelial cell plasticity
-
Ozdamar B, Bose R, Barrios-Rodiles M, Wang HR, Zhang Y, Wrana JL. 2005. Regulation of the polarity protein Par6 by TGF-β receptors controls epithelial cell plasticity. Science 307:1603-1609.
-
(2005)
Science
, vol.307
, pp. 1603-1609
-
-
Ozdamar, B.1
Bose, R.2
Barrios-Rodiles, M.3
Wang, H.R.4
Zhang, Y.5
Wrana, J.L.6
-
25
-
-
0035797521
-
Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP
-
Pak DTS, Yang S, Rudolph-Correia S, Kim E, Sheng M. 2001. Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP. Neuron 31:289-303.
-
(2001)
Neuron
, vol.31
, pp. 289-303
-
-
Pak, D.T.S.1
Yang, S.2
Rudolph-Correia, S.3
Kim, E.4
Sheng, M.5
-
26
-
-
32044453541
-
p120-catenin mediates inflammatory response in the skin
-
Perez-Moreno M, Davis MA, Wong E, Pasolli HA, Reynolds AB. 2006. p120-catenin mediates inflammatory response in the skin. Cell 124:631-644.
-
(2006)
Cell
, vol.124
, pp. 631-644
-
-
Perez-Moreno, M.1
Davis, M.A.2
Wong, E.3
Pasolli, H.A.4
Reynolds, A.B.5
-
27
-
-
0031034469
-
Activation of the nuclear factor-κB by Rho, Cdc42, and Rac-1 proteins
-
Perona R, Montaner S, Saniger L, Sanchez-Perez I, Bravo R, Lacal JC. 1997. Activation of the nuclear factor-κB by Rho, Cdc42, and Rac-1 proteins. Genes Dev 11:463-475.
-
(1997)
Genes Dev
, vol.11
, pp. 463-475
-
-
Perona, R.1
Montaner, S.2
Saniger, L.3
Sanchez-Perez, I.4
Bravo, R.5
Lacal, J.C.6
-
28
-
-
0034689050
-
The small GTPase, Rap1, mediates CD31-induced integrin adhesion
-
Reedquist KA, Ross E, Koop EA, Wolthuis RM, Zwartkruis FJ, van Kooyk Y, Salmon M, Buckley CD, Bos JL. 2000. The small GTPase, Rap1, mediates CD31-induced integrin adhesion. J Cell Biol 148:1151-1158.
-
(2000)
J Cell Biol
, vol.148
, pp. 1151-1158
-
-
Reedquist, K.A.1
Ross, E.2
Koop, E.A.3
Wolthuis, R.M.4
Zwartkruis, F.J.5
van Kooyk, Y.6
Salmon, M.7
Buckley, C.D.8
Bos, J.L.9
-
29
-
-
0033777071
-
Determination of GTP loading on Rho
-
Ren XD, Schwartz MA. 2000. Determination of GTP loading on Rho. Med Enzymol 325:264-272.
-
(2000)
Med Enzymol
, vol.325
, pp. 264-272
-
-
Ren, X.D.1
Schwartz, M.A.2
-
30
-
-
80955176384
-
Reversal of TGF-β1 stimulation of α-smooth muscle actin and extracellular matrix components by cyclic AMP in Dupuytren's-derived fibroblasts
-
Satish L, Gallo PH, Baratz ME, Johnson S, Kathju S. 2011. Reversal of TGF-β1 stimulation of α-smooth muscle actin and extracellular matrix components by cyclic AMP in Dupuytren's-derived fibroblasts. BMC Musculoskelet Disord 12:113.
-
(2011)
BMC Musculoskelet Disord
, vol.12
, pp. 113
-
-
Satish, L.1
Gallo, P.H.2
Baratz, M.E.3
Johnson, S.4
Kathju, S.5
-
31
-
-
0036161707
-
PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1
-
Schmitt JM, Stork PJS. 2002. PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1. Mol Cell 9:85-94.
-
(2002)
Mol Cell
, vol.9
, pp. 85-94
-
-
Schmitt, J.M.1
Stork, P.J.S.2
-
32
-
-
33847641512
-
Involvement of nuclear factor-κB activation through RhoA/Rho-kinase pathway in LPS-induced IL-8 production in human cervical stromal cells
-
Shimizu S, Tahara M, Ogata S, Hashimoto K, Morishige K, Tasaka K, Murata Y. 2007. Involvement of nuclear factor-κB activation through RhoA/Rho-kinase pathway in LPS-induced IL-8 production in human cervical stromal cells. Mol Hum Reprod 13:181-187.
-
(2007)
Mol Hum Reprod
, vol.13
, pp. 181-187
-
-
Shimizu, S.1
Tahara, M.2
Ogata, S.3
Hashimoto, K.4
Morishige, K.5
Tasaka, K.6
Murata, Y.7
-
33
-
-
12344338685
-
ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner
-
Stacey I, Nie Z, Stewart A, Najdovska M, Hall NE, He H, Randazzo PA, Lock P. 2004. ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner. J Cell Sci 117:6071-6084.
-
(2004)
J Cell Sci
, vol.117
, pp. 6071-6084
-
-
Stacey, I.1
Nie, Z.2
Stewart, A.3
Najdovska, M.4
Hall, N.E.5
He, H.6
Randazzo, P.A.7
Lock, P.8
-
34
-
-
0038741814
-
Does Rap1 deserve a bad Rap
-
Stork PJS. 2003. Does Rap1 deserve a bad Rap? Trends Biochem Sci 28:267-275.
-
(2003)
Trends Biochem Sci
, vol.28
, pp. 267-275
-
-
Stork, P.J.S.1
-
35
-
-
27644475483
-
Multiple roles of Rap1 in hematopoietic cells: Complementary versus antagonistic functions
-
Stork PJS, Dillon TJ. 2005. Multiple roles of Rap1 in hematopoietic cells: Complementary versus antagonistic functions. Blood 106:2952-2961.
-
(2005)
Blood
, vol.106
, pp. 2952-2961
-
-
Stork, P.J.S.1
Dillon, T.J.2
-
36
-
-
0025125049
-
Macrophage production of TGF-β and regulation by TGF-β
-
Wahl SM, McCartney-Francis N, Allen JB, Dougherty EB, Dougherty SF. 1990. Macrophage production of TGF-β and regulation by TGF-β. Ann NY Acad Sci 593:188-196.
-
(1990)
Ann NY Acad Sci
, vol.593
, pp. 188-196
-
-
Wahl, S.M.1
McCartney-Francis, N.2
Allen, J.B.3
Dougherty, E.B.4
Dougherty, S.F.5
-
37
-
-
0344758986
-
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
-
Wang HR, Zhang Y, Ozdamar B, Ogunjimi AA, Alexandrova E, Thomsen GH, Wrana JL. 2003. Regulation of cell polarity and protrusion formation by targeting RhoA for degradation. Science 302:1775-1779.
-
(2003)
Science
, vol.302
, pp. 1775-1779
-
-
Wang, H.R.1
Zhang, Y.2
Ozdamar, B.3
Ogunjimi, A.A.4
Alexandrova, E.5
Thomsen, G.H.6
Wrana, J.L.7
-
38
-
-
13244292533
-
Trading spaces: Rap1, Rac, and Rho as architects of transendothelial migration
-
Wittchen ES, van Buul JD, Burridge K, Worthylake RA. 2005. Trading spaces: Rap1, Rac, and Rho as architects of transendothelial migration. Curr Opin Hematol 12:14-21.
-
(2005)
Curr Opin Hematol
, vol.12
, pp. 14-21
-
-
Wittchen, E.S.1
van Buul, J.D.2
Burridge, K.3
Worthylake, R.A.4
-
39
-
-
59449094893
-
Effect of cAMP on TGF-β1-induced corneal keratinocyte-myofibroblast transformation
-
Xing D, Bonanno JA. 2009. Effect of cAMP on TGF-β1-induced corneal keratinocyte-myofibroblast transformation. Invest Ophtalmol Vis Sci 50:626-633.
-
(2009)
Invest Ophtalmol Vis Sci
, vol.50
, pp. 626-633
-
-
Xing, D.1
Bonanno, J.A.2
-
40
-
-
33646563695
-
Pro- and antiinflammatory cytokine signaling: Reciprocal antagonism regulates interferon-gamma production by human natural killer cells
-
Yu J, Wei M, Becknell B, Trotta R, Liu S, Boyd Z, Jaung MS, Blaser BW, Sun J, Benson DM, Jr., Mao H, Yokohama A, Bhatt D, Shen L, Davuluri R, Weinstein M, Marcucci G, Caligiuri MA. 2006. Pro- and antiinflammatory cytokine signaling: Reciprocal antagonism regulates interferon-gamma production by human natural killer cells. Immunity 24:575-590.
-
(2006)
Immunity
, vol.24
, pp. 575-590
-
-
Yu, J.1
Wei, M.2
Becknell, B.3
Trotta, R.4
Liu, S.5
Boyd, Z.6
Jaung, M.S.7
Blaser, B.W.8
Sun, J.9
Benson Jr, D.M.10
Mao, H.11
Yokohama, A.12
Bhatt, D.13
Shen, L.14
Davuluri, R.15
Weinstein, M.16
Marcucci, G.17
Caligiuri, M.A.18
-
41
-
-
58149213801
-
Non-Smad pathways in TGF-β signaling
-
Zhang YE. 2009. Non-Smad pathways in TGF-β signaling. Cell Res 10:128-139.
-
(2009)
Cell Res
, vol.10
, pp. 128-139
-
-
Zhang, Y.E.1
|