Opioid μ-receptors as new target for insulin resistance

Pharmacology and Therapeutics

Volumn 139, Issue 3, 2013, Pages 334-340

  Cheng, Kai Chun ^a   Asakawa, Akihiro ^a   Li, Ying Xiao ^a   Liu, I Min ^b   Amitani, Haruka ^a   Cheng, Juei Tang ^c   Inui, Akio ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b TAJEN UNIVERSITY   (Taiwan)

^c CHI MEI MEDICAL CENTER   (Taiwan)

Author keywords

Endorphin; Insulin resistance; Loperamide; Opioid receptor; Opioids; Signals

Indexed keywords

ENDORPHIN; GLUCOSE; INSULIN; INSULIN RECEPTOR; MU OPIATE RECEPTOR; PROTEIN KINASE C ZETA;

GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION;

CENTRAL NERVOUS SYSTEM; CNS; DAG; DIACYLGLYCEROL; DOR; GDR; GLUCOSE DISPOSAL; GLUT4; HEPATIC PHOSPHOENOLPYRUVATE CARBOXYKINASE; IL; INCLUDING INTERLEUKIN; INSULIN RECEPTOR SUBSTRATE; INSULIN RESISTANCE; IRS; JNK; JUN N-TERMINAL KINASE; KOR; LOPERAMIDE; MOR; MUSCLE GLUCOSE TRANSPORTERS SUBTYPE 4 FORM; OPIOID Μ-RECEPTOR; OPIOIDS; PDK; PEPCK; PHOSPHATIDYLINOSITOL 3; PHOSPHATIDYLINOSITOL 3,4,5 TRIPHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOINOSITIDE-DEPENDENT KINASE; PHOSPHOLIPASE C; PI3; PIP2; PIP3; PKC; PLC; PROTEIN KINASE C; SIGNALS; TNF; TUMOR NECROSIS FACTOR; Β-ENDORPHIN; Δ OPIOID RECEPTORS; Κ OPIOID RECEPTORS; Μ OPIOID RECEPTOR;

ANIMALS; DIABETES MELLITUS, TYPE 2; GLUCOSE; HUMANS; INSULIN; INSULIN RESISTANCE; LOPERAMIDE; MICE; MICE, KNOCKOUT; OPIOID PEPTIDES; RATS; RATS, ZUCKER; RECEPTORS, OPIOID, MU; SIGNAL TRANSDUCTION;

EID: 84881223391     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2013.05.002     Document Type: Review

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