Activation of peripheral opioid μ-receptors in blood vessel may lower blood pressure in spontaneously hypertensive rats

Pharmacology

Volumn 87, Issue 5-6, 2011, Pages 257-264

  Chen, Zhih Cherng ^a   Shieh, Ja Ping ^a,c   Chung, Hsien Hui ^b   Hung, Ching Hsia ^b   Lin, Hung Jung ^a   Cheng, Juei Tang ^a,b  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c Chia Nan University of Pharmacy and Sciences   (Taiwan)

Author keywords

ATP sensitive K+ channels; Forskolin; Loperamide; Opioid receptor; Spontaneously hypertensive rats; Vasodilatation

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYPRODIME; GLIBENCLAMIDE; LOPERAMIDE; MU OPIATE RECEPTOR; NALOXONAZINE; PHENYLEPHRINE; PHOSPHODIESTERASE INHIBITOR; VASOPRESSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DOSE RESPONSE; HEART OUTPUT; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; MOLECULAR MECHANICS; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR RING; VASODILATATION;

ANIMALS; ARTERIES; BLOOD PRESSURE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENDOTHELIUM; GLYBURIDE; HEMODYNAMICS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KATP CHANNELS; LOPERAMIDE; MALE; MORPHINANS; NALOXONE; PHENYLEPHRINE; PHOSPHODIESTERASE INHIBITORS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTORS, OPIOID, MU; VASODILATION;

EID: 79953861171     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000326084     Document Type: Article

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