메뉴 건너뛰기




Volumn 8, Issue 1, 2013, Pages

Autophagy is involved in oligodendroglial precursor-mediated clearance of amyloid peptide

Author keywords

amyloid degradation; Alzheimer's disease; Autophagy; Endocytosis; NG2 cells

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; BAFILOMYCIN A1; BECLIN 1; WORTMANNIN;

EID: 84881152101     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/1750-1326-8-27     Document Type: Article
Times cited : (51)

References (74)
  • 1
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • Alzheimer's disease: genes, proteins, and therapy. Selkoe DJ, Physiol Rev 2001 81 741 766 11274343 (Pubitemid 32267077)
    • (2001) Physiological Reviews , vol.81 , Issue.2 , pp. 741-766
    • Selkoe, D.J.1
  • 2
    • 75449102536 scopus 로고    scopus 로고
    • Alzheimer's disease
    • 10.1056/NEJMra0909142 20107219
    • Alzheimer's disease. Querfurth HW, LaFerla FM, N Engl J Med 2010 362 329 344 10.1056/NEJMra0909142 20107219
    • (2010) N Engl J Med , vol.362 , pp. 329-344
    • Querfurth, H.W.1    Laferla, F.M.2
  • 3
    • 13944276825 scopus 로고    scopus 로고
    • Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
    • DOI 10.1016/j.cell.2005.02.008
    • Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Tanzi RE, Bertram L, Cell 2005 120 545 555 10.1016/j.cell.2005.02. 008 15734686 (Pubitemid 40269768)
    • (2005) Cell , vol.120 , Issue.4 , pp. 545-555
    • Tanzi, R.E.1    Bertram, L.2
  • 4
    • 34250819839 scopus 로고    scopus 로고
    • Intracellular amyloid-β in Alzheimer's disease
    • DOI 10.1038/nrn2168, PII NRN2168
    • Intracellular amyloid-beta in Alzheimer's disease. LaFerla FM, Green KN, Oddo S, Nat Rev Neurosci 2007 8 499 509 10.1038/nrn2168 17551515 (Pubitemid 46985362)
    • (2007) Nature Reviews Neuroscience , vol.8 , Issue.7 , pp. 499-509
    • LaFerla, F.M.1    Green, K.N.2    Oddo, S.3
  • 5
    • 77954116814 scopus 로고    scopus 로고
    • Autophagy gone awry in neurodegenerative diseases
    • 10.1038/nn.2575 20581817
    • Autophagy gone awry in neurodegenerative diseases. Wong E, Cuervo AM, Nat Neurosci 2010 13 805 811 10.1038/nn.2575 20581817
    • (2010) Nat Neurosci , vol.13 , pp. 805-811
    • Wong, E.1    Cuervo, A.M.2
  • 8
    • 0023404196 scopus 로고
    • Light and electron microscopic localization of a cell surface antigen (NG2) in the rat cerebellum: Association with smooth protoplasmic astrocytes
    • 3305798
    • Light and electron microscopic localization of a cell surface antigen (NG2) in the rat cerebellum: association with smooth protoplasmic astrocytes. Levine JM, Card JP, J Neurosci 1987 7 2711 2720 3305798
    • (1987) J Neurosci , vol.7 , pp. 2711-2720
    • Levine, J.M.1    Card, J.P.2
  • 9
    • 0035060665 scopus 로고    scopus 로고
    • The oligodendrocyte precursor cell in health and disease
    • DOI 10.1016/S0166-2236(00)01691-X, PII S016622360001691X
    • The oligodendrocyte precursor cell in health and disease. Levine JM, Reynolds R, Fawcett JW, Trends Neurosci 2001 24 39 47 11163886 (Pubitemid 32332895)
    • (2001) Trends in Neurosciences , vol.24 , Issue.1 , pp. 39-47
    • Levine, J.M.1    Reynolds, R.2    Fawcett, J.W.3
  • 10
    • 33845985597 scopus 로고    scopus 로고
    • Polydendrocytes: NG2 cells with many roles in development and repair of the CNS
    • DOI 10.1177/1073858406295586
    • Polydendrocytes: NG2 cells with many roles in development and repair of the CNS. Nishiyama A, Neuroscientist 2007 13 62 76 10.1177/1073858406295586 17229976 (Pubitemid 46052754)
    • (2007) Neuroscientist , vol.13 , Issue.1 , pp. 62-76
    • Nishiyama, A.1
  • 11
    • 0034284392 scopus 로고    scopus 로고
    • NG2-expressing cells in the central nervous system: Are they oligodendroglial progenitors?
    • 10.1002/1097-4547(20000901)61:5<471: AID-JNR1>3.0.CO;2-N 10956416
    • NG2-expressing cells in the central nervous system: are they oligodendroglial progenitors? Dawson MR, Levine JM, Reynolds R, J Neurosci Res 2000 61 471 479 10.1002/1097-4547(20000901)61:5<471::AID-JNR1>3.0.CO;2-N 10956416
    • (2000) J Neurosci Res , vol.61 , pp. 471-479
    • Dawson, M.R.1    Levine, J.M.2    Reynolds, R.3
  • 12
    • 0033103253 scopus 로고    scopus 로고
    • Cells expressing the NG2 antigen contact nodes of ranvier in adult CNS white matter
    • DOI 10.1002/(SICI)1098-1136(199903)26:1<84::AID-GLIA9>3.0.CO;2-L
    • Cells expressing the NG2 antigen contact nodes of Ranvier in adult CNS white matter. Butt AM, Duncan A, Hornby MF, Kirvell SL, Hunter A, Levine JM, Berry M, Glia 1999 26 84 91 10.1002/(SICI)1098-1136(199903)26:1<84::AID- GLIA9>3.0.CO;2-L 10088675 (Pubitemid 29103171)
    • (1999) GLIA , vol.26 , Issue.1 , pp. 84-91
    • Butt, A.M.1    Duncan, A.2    Hornby, M.F.3    Kirvell, S.L.4    Hunter, A.5    Levine, J.M.6    Berry, M.7
  • 13
    • 0034636493 scopus 로고    scopus 로고
    • Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus
    • DOI 10.1038/35012083
    • Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus. Bergles DE, Roberts JD, Somogyi P, Jahr CE, Nature 2000 405 187 191 10.1038/35012083 10821275 (Pubitemid 30313537)
    • (2000) Nature , vol.405 , Issue.6783 , pp. 187-191
    • Bergles, D.E.1    Roberts, J.D.B.2    Somogyl, P.3    Jahr, C.E.4
  • 14
    • 33744980237 scopus 로고    scopus 로고
    • 2+-permeable AMPA receptors
    • DOI 10.1126/science.1124669
    • Long-term potentiation of neuron-glia synapses mediated by Ca2 + -permeable AMPA receptors. Ge WP, Yang XJ, Zhang Z, Wang HK, Shen W, Deng QD, Duan S, Science 2006 312 1533 1537 10.1126/science.1124669 16763153 (Pubitemid 43865894)
    • (2006) Science , vol.312 , Issue.5779 , pp. 1533-1537
    • Ge, W.-P.1    Yang, X.-J.2    Zhang, Z.3    Wang, H.-K.4    Shen, W.5    Deng, Q.-D.6    Duan, S.7
  • 15
    • 0037437148 scopus 로고    scopus 로고
    • Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons
    • DOI 10.1083/jcb.200210110
    • Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons. Belachew S, Chittajallu R, Aguirre AA, Yuan X, Kirby M, Anderson S, Gallo V, J Cell Biol 2003 161 169 186 10.1083/jcb.200210110 12682089 (Pubitemid 36459089)
    • (2003) Journal of Cell Biology , vol.161 , Issue.1 , pp. 169-186
    • Belachew, S.1    Chittajallu, R.2    Aguirre, A.A.3    Yuan, X.4    Kirby, M.5    Anderson, S.6    Gallo, V.7
  • 16
    • 56749156453 scopus 로고    scopus 로고
    • PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice
    • 10.1038/nn.2220 18849983
    • PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice. Rivers LE, Young KM, Rizzi M, Jamen F, Psachoulia K, Wade A, Kessaris N, Richardson WD, Nat Neurosci 2008 11 1392 1401 10.1038/nn.2220 18849983
    • (2008) Nat Neurosci , vol.11 , pp. 1392-1401
    • Rivers, L.E.1    Young, K.M.2    Rizzi, M.3    Jamen, F.4    Psachoulia, K.5    Wade, A.6    Kessaris, N.7    Richardson, W.D.8
  • 17
    • 0036550340 scopus 로고    scopus 로고
    • NG2 Is a Major Chondroitin Sulfate Proteoglycan Produced after Spinal Cord Injury and Is Expressed by Macrophages and Oligodendrocyte Progenitors
    • NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors. Jones LL, Yamaguchi Y, Stallcup WB, Tuszynski MH, J Neurosci 2002 22 2792 2803 11923444 (Pubitemid 37465828)
    • (2002) Journal of Neuroscience , vol.22 , Issue.7 , pp. 2792-2803
    • Jones, L.L.1    Yamaguchi, Y.2    Stallcup, W.B.3    Tuszynski, M.H.4
  • 18
    • 0033038038 scopus 로고    scopus 로고
    • A light and electron microscopic study of NG2 chondroitin sulfate proteoglycan-positive oligodendrocyte precursor cells in the normal and kainate-lesioned rat hippocampus
    • DOI 10.1016/S0306-4522(98)00751-9, PII S0306452298007519
    • A light and electron microscopic study of NG2 chondroitin sulfate proteoglycan-positive oligodendrocyte precursor cells in the normal and kainate-lesioned rat hippocampus. Ong WY, Levine JM, Neuroscience 1999 92 83 95 10.1016/S0306-4522(98)00751-9 10392832 (Pubitemid 29249020)
    • (1999) Neuroscience , vol.92 , Issue.1 , pp. 83-95
    • Ong, W.Y.1    Levine, J.M.2
  • 19
    • 0032146833 scopus 로고    scopus 로고
    • Reactions of oligodendrocyte precursor cells to alpha herpesvirus infection of the central nervous system
    • DOI 10.1002/(SICI)1098-1136(199808)23:4<316::AID-GLIA4>3.0.CO;2-0
    • Reactions of oligodendrocyte precursor cells to alpha herpesvirus infection of the central nervous system. Levine JM, Enquist LW, Card JP, Glia 1998 23 316 328 10.1002/(SICI)1098-1136(199808)23:4<316::AID-GLIA4>3.0. CO;2-0 9671962 (Pubitemid 28320598)
    • (1998) GLIA , vol.23 , Issue.4 , pp. 316-328
    • Levine, J.M.1    Enquist, L.W.2    Card, J.P.3
  • 20
    • 37349108615 scopus 로고    scopus 로고
    • The ameboid phenotype of NG2 (+) cells in the region of apoptotic dentate granule neurons in trimethyltin intoxicated mice shares antigen properties with microglia/macrophages
    • DOI 10.1002/glia.20605
    • The ameboid phenotype of NG2 (+) cells in the region of apoptotic dentate granule neurons in trimethyltin intoxicated mice shares antigen properties with microglia/macrophages. Fiedorowicz A, Figiel I, Zaremba M, Dzwonek K, Oderfeld-Nowak B, Glia 2008 56 209 222 10.1002/glia.20605 18023017 (Pubitemid 350292313)
    • (2008) GLIA , vol.56 , Issue.2 , pp. 209-222
    • Fiedorowicz, A.1    Figiel, I.2    Zaremba, M.3    Dzwonek, K.4    Oderfeld-Nowak, B.5
  • 21
    • 0028095147 scopus 로고
    • Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury
    • Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury. Levine JM, J Neurosci 1994 14 4716 4730 8046446 (Pubitemid 24237894)
    • (1994) Journal of Neuroscience , vol.14 , Issue.8 , pp. 4716-4730
    • Levine, J.M.1
  • 22
    • 0034950456 scopus 로고    scopus 로고
    • Transient expression of the NG2 proteoglycan by a subpopulation of activated macrophages in an excitotoxic hippocampal lesion
    • DOI 10.1002/glia.1063
    • Transient expression of the NG2 proteoglycan by a subpopulation of activated macrophages in an excitotoxic hippocampal lesion. Bu J, Akhtar N, Nishiyama A, Glia 2001 34 296 310 10.1002/glia.1063 11360302 (Pubitemid 32579452)
    • (2001) GLIA , vol.34 , Issue.4 , pp. 296-310
    • Bu, J.1    Akhtar, N.2    Nishiyama, A.3
  • 23
    • 0035873062 scopus 로고    scopus 로고
    • Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord
    • Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord. McTigue DM, Wei P, Stokes BT, J Neurosci 2001 21 3392 3400 11331369 (Pubitemid 32422804)
    • (2001) Journal of Neuroscience , vol.21 , Issue.10 , pp. 3392-3400
    • McTigue, D.M.1    Wei, P.2    Stokes, B.T.3
  • 26
    • 32344440522 scopus 로고    scopus 로고
    • Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
    • DOI 10.1016/j.neuron.2006.01.022, PII S0896627306000754
    • Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Simard AR, Soulet D, Gowing G, Julien JP, Rivest S, Neuron 2006 49 489 502 10.1016/j.neuron.2006.01.022 16476660 (Pubitemid 43221886)
    • (2006) Neuron , vol.49 , Issue.4 , pp. 489-502
    • Simard, A.R.1    Soulet, D.2    Gowing, G.3    Julien, J.-P.4    Rivest, S.5
  • 27
    • 65249170245 scopus 로고    scopus 로고
    • Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis
    • 10.1523/JNEUROSCI.5572-08.2009 19339619
    • Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis. Mandrekar S, Jiang Q, Lee CY, Koenigsknecht-Talboo J, Holtzman DM, Landreth GE, J Neurosci 2009 29 4252 4262 10.1523/JNEUROSCI.5572-08.2009 19339619
    • (2009) J Neurosci , vol.29 , pp. 4252-4262
    • Mandrekar, S.1    Jiang, Q.2    Lee, C.Y.3    Koenigsknecht-Talboo, J.4    Holtzman, D.M.5    Landreth, G.E.6
  • 29
    • 34249937267 scopus 로고    scopus 로고
    • β-amyloid is a substrate of autophagy in sporadic inclusion body myositis
    • DOI 10.1002/ana.21115
    • Beta-amyloid is a substrate of autophagy in sporadic inclusion body myositis. Lunemann JD, Schmidt J, Schmid D, Barthel K, Wrede A, Dalakas MC, Munz C, Ann Neurol 2007 61 476 483 10.1002/ana.21115 17469125 (Pubitemid 46878775)
    • (2007) Annals of Neurology , vol.61 , Issue.5 , pp. 476-483
    • Lunemann, J.D.1    Schmidt, J.2    Schmid, D.3    Barthel, K.4    Wrede, A.5    Dalakas, M.C.6    Munz, C.7
  • 30
    • 38349046973 scopus 로고    scopus 로고
    • Autophagy, amyloidogenesis and Alzheimer disease
    • 10.1242/jcs.019265 18032783
    • Autophagy, amyloidogenesis and Alzheimer disease. Nixon RA, J Cell Sci 2007 120 4081 4091 10.1242/jcs.019265 18032783
    • (2007) J Cell Sci , vol.120 , pp. 4081-4091
    • Nixon, R.A.1
  • 31
    • 0030915855 scopus 로고    scopus 로고
    • Oxidative stress hypothesis in Alzheimer's disease
    • DOI 10.1016/S0891-5849(96)00629-6, PII S0891584996006296
    • Oxidative stress hypothesis in Alzheimer's disease. Markesbery WR, Free Radic Biol Med 1997 23 134 147 10.1016/S0891-5849(96)00629-6 9165306 (Pubitemid 27217017)
    • (1997) Free Radical Biology and Medicine , vol.23 , Issue.1 , pp. 134-147
    • Markesbery, W.R.1
  • 32
    • 33748471099 scopus 로고    scopus 로고
    • Inflammation in Alzheimer disease: Driving force, bystander or beneficial response?
    • DOI 10.1038/nm1484, PII NM1484
    • Inflammation in Alzheimer disease: driving force, bystander or beneficial response? Wyss-Coray T, Nat Med 2006 12 1005 1015 16960575 (Pubitemid 44353380)
    • (2006) Nature Medicine , vol.12 , Issue.9 , pp. 1005-1015
    • Wyss-Coray, T.1
  • 33
    • 33745920161 scopus 로고    scopus 로고
    • Human amyloid-β synthesis and clearance rates as measured in cerebrospinal fluid in vivo
    • DOI 10.1038/nm1438, PII NM1438
    • Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo. Bateman RJ, Munsell LY, Morris JC, Swarm R, Yarasheski KE, Holtzman DM, Nat Med 2006 12 856 861 10.1038/nm1438 16799555 (Pubitemid 44050079)
    • (2006) Nature Medicine , vol.12 , Issue.7 , pp. 856-861
    • Bateman, R.J.1    Munsell, L.Y.2    Morris, J.C.3    Swarm, R.4    Yarasheski, K.E.5    Holtzman, D.M.6
  • 34
    • 0033527637 scopus 로고    scopus 로고
    • Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid β-peptide by microglial cells
    • DOI 10.1074/jbc.274.45.32301
    • Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells. Chung H, Brazil MI, Soe TT, Maxfield FR, J Biol Chem 1999 274 32301 32308 10.1074/jbc.274.45.32301 10542270 (Pubitemid 29522974)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.45 , pp. 32301-32308
    • Chung, H.1    Brazil, M.I.2    Soe, T.T.3    Maxfield, F.R.4
  • 35
    • 56349166514 scopus 로고    scopus 로고
    • Mechanisms of microglia accumulation in Alzheimer's disease: Therapeutic implications
    • 10.1016/j.tips.2008.08.004 18835047
    • Mechanisms of microglia accumulation in Alzheimer's disease: therapeutic implications. El Khoury J, Luster AD, Trends Pharmacol Sci 2008 29 626 632 10.1016/j.tips.2008.08.004 18835047
    • (2008) Trends Pharmacol Sci , vol.29 , pp. 626-632
    • El Khoury, J.1    Luster, A.D.2
  • 37
    • 65449120034 scopus 로고    scopus 로고
    • Virus entry by macropinocytosis
    • 10.1038/ncb0509-510 19404330
    • Virus entry by macropinocytosis. Mercer J, Helenius A, Nat Cell Biol 2009 11 510 520 10.1038/ncb0509-510 19404330
    • (2009) Nat Cell Biol , vol.11 , pp. 510-520
    • Mercer, J.1    Helenius, A.2
  • 38
    • 63049113263 scopus 로고    scopus 로고
    • Defining macropinocytosis
    • 10.1111/j.1600-0854.2009.00878.x 19192253
    • Defining macropinocytosis. Kerr MC, Teasdale RD, Traffic 2009 10 364 371 10.1111/j.1600-0854.2009.00878.x 19192253
    • (2009) Traffic , vol.10 , pp. 364-371
    • Kerr, M.C.1    Teasdale, R.D.2
  • 39
    • 0024517745 scopus 로고
    • Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro
    • DOI 10.1083/jcb.108.4.1301
    • Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro. Gruenberg J, Griffiths G, Howell KE, J Cell Biol 1989 108 1301 1316 10.1083/jcb.108.4.1301 2538480 (Pubitemid 19097039)
    • (1989) Journal of Cell Biology , vol.108 , Issue.4 , pp. 1301-1316
    • Gruenberg, J.1    Griffiths, G.2    Howell, K.E.3
  • 40
    • 0029100974 scopus 로고
    • Membrane transport in the endocytic pathway
    • 10.1016/0955-0674(95)80013-1 7495576
    • Membrane transport in the endocytic pathway. Gruenberg J, Maxfield FR, Curr Opin Cell Biol 1995 7 552 563 10.1016/0955-0674(95)80013-1 7495576
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 552-563
    • Gruenberg, J.1    Maxfield, F.R.2
  • 41
    • 0023576902 scopus 로고
    • Translocation and clustering of endosomes and lysosomes depends on microtubules
    • Translocation and clustering of endosomes and lysosomes depends on microtubules. Matteoni R, Kreis TE, J Cell Biol 1987 105 1253 1265 10.1083/jcb.105.3.1253 3308906 (Pubitemid 18029849)
    • (1987) Journal of Cell Biology , vol.105 , Issue.3 , pp. 1253-1265
    • Matteoni, R.1    Kreis, T.E.2
  • 43
    • 0035158645 scopus 로고    scopus 로고
    • 42) is internalized via the G-protein-coupled receptor FPRL1 and forms fibrillar aggregates in macrophages
    • DOI 10.1096/fj.01-0251com
    • Beta amyloid peptide (Abeta42) is internalized via the G-protein-coupled receptor FPRL1 and forms fibrillar aggregates in macrophages. Yazawa H, Yu ZX, Takeda Le Y, Gong W, Ferrans VJ, Oppenheim JJ, Li CC, Wang JM, FASEB J 2001 15 2454 2462 10.1096/fj.01-0251com 11689470 (Pubitemid 33063173)
    • (2001) FASEB Journal , vol.15 , Issue.13 , pp. 2454-2462
    • Yazawa, H.1    Yu, Z.-X.2    Takeda, K.3    Le, Y.4    Gong, W.5    Ferrans, V.J.6    Oppenheim, J.J.7    Li, C.C.H.8    Wang, J.M.9
  • 45
    • 33750576993 scopus 로고    scopus 로고
    • Role of toll-like receptor signalling in Aβ uptake and clearance
    • DOI 10.1093/brain/awl249
    • Role of toll-like receptor signalling in Abeta uptake and clearance. Tahara K, Kim HD, Jin JJ, Maxwell JA, Li L, Fukuchi K, Brain 2006 129 3006 3019 10.1093/brain/awl249 16984903 (Pubitemid 44684521)
    • (2006) Brain , vol.129 , Issue.11 , pp. 3006-3019
    • Tahara, K.1    Kim, H.-D.2    Jin, J.-J.3    Maxwell, J.A.4    Li, L.5    Fukuchi, K.-I.6
  • 46
    • 63849213473 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor signalling: Roles in Alzheimer's disease and amyloid neuroprotection
    • 10.1124/pr.108.000562 19293145
    • Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection. Buckingham SD, Jones AK, Brown LA, Sattelle DB, Pharmacol Rev 2009 61 39 61 10.1124/pr.108.000562 19293145
    • (2009) Pharmacol Rev , vol.61 , pp. 39-61
    • Buckingham, S.D.1    Jones, A.K.2    Brown, L.A.3    Sattelle, D.B.4
  • 47
    • 67349270965 scopus 로고    scopus 로고
    • Apolipoprotein e and its receptors in Alzheimer's disease: Pathways, pathogenesis and therapy
    • 10.1038/nrn2620 19339974
    • Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy. Bu G, Nat Rev Neurosci 2009 10 333 344 10.1038/nrn2620 19339974
    • (2009) Nat Rev Neurosci , vol.10 , pp. 333-344
    • Bu, G.1
  • 48
    • 34250811784 scopus 로고    scopus 로고
    • LRP in amyloid-β production and metabolism
    • DOI 10.1196/annals.1377.005, Integrated Molecular Medicine for Neuronal and Neoplastic Disorders
    • LRP in amyloid-beta production and metabolism. Bu G, Cam J, Zerbinatti C, Ann N Y Acad Sci 2006 1086 35 53 10.1196/annals.1377.005 17185504 (Pubitemid 47084373)
    • (2006) Annals of the New York Academy of Sciences , vol.1086 , pp. 35-53
    • Bu, G.1    Cam, J.2    Zerbinatti, C.3
  • 50
    • 35948958216 scopus 로고    scopus 로고
    • Erratum: HDAC6 at the intersection of autophagy, the ubiquitin-proteasome system and neurodegeneration (Autophagy)
    • HDAC6 at the intersection of autophagy, the ubiquitin-proteasome system and neurodegeneration. Pandey UB, Batlevi Y, Baehrecke EH, Taylor JP, Autophagy 2007 3 643 645 17912024 (Pubitemid 350064219)
    • (2007) Autophagy , vol.3 , Issue.6 , pp. 643-645
    • Pandey, U.B.1    Batlevi, Y.2    Baehrecke, E.H.3    Taylor, J.P.4
  • 52
    • 0028947294 scopus 로고
    • Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: Evidence for early up-regulation of the endosomal-lysosomal system
    • 10.1016/0896-6273(95)90324-0 7695914
    • Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system. Cataldo AM, Barnett JL, Berman SA, Li J, Quarless S, Bursztajn S, Lippa C, Nixon RA, Neuron 1995 14 671 680 10.1016/0896-6273(95)90324-0 7695914
    • (1995) Neuron , vol.14 , pp. 671-680
    • Cataldo, A.M.1    Barnett, J.L.2    Berman, S.A.3    Li, J.4    Quarless, S.5    Bursztajn, S.6    Lippa, C.7    Nixon, R.A.8
  • 53
    • 0030836345 scopus 로고    scopus 로고
    • Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: Neuropathologic evidence for a mechanism of increased β-amyloidogenesis
    • Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: neuropathologic evidence for a mechanism of increased beta-amyloidogenesis. Cataldo AM, Barnett JL, Pieroni C, Nixon RA, J Neurosci 1997 17 6142 6151 9236226 (Pubitemid 27329890)
    • (1997) Journal of Neuroscience , vol.17 , Issue.16 , pp. 6142-6151
    • Cataldo, A.M.1    Barnett, J.L.2    Pieroni, C.3    Nixon, R.A.4
  • 55
    • 33748524564 scopus 로고    scopus 로고
    • Antiamyloidogenic and neuroprotective functions of cathepsin B: Implications for alzheimer's disease
    • DOI 10.1016/j.neuron.2006.07.027, PII S0896627306005976
    • Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease. Mueller-Steiner S, Zhou Y, Arai H, Roberson ED, Sun B, Chen J, Wang X, Yu G, Esposito L, Mucke L, Gan L, Neuron 2006 51 703 714 10.1016/j.neuron.2006.07.027 16982417 (Pubitemid 44374903)
    • (2006) Neuron , vol.51 , Issue.6 , pp. 703-714
    • Mueller-Steiner, S.1    Zhou, Y.2    Arai, H.3    Roberson, E.D.4    Sun, B.5    Chen, J.6    Wang, X.7    Yu, G.8    Esposito, L.9    Mucke, L.10    Gan, L.11
  • 57
    • 0000906170 scopus 로고    scopus 로고
    • Induction of autophagy and inhibition of tumorigenesis by beclin 1
    • Induction of autophagy and inhibition of tumorigenesis by beclin 1. Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, Levine B, Nature 1999 402 672 676 10.1038/45257 10604474 (Pubitemid 129516338)
    • (1999) Nature , vol.402 , Issue.6762 , pp. 672-676
    • Liang, X.H.1    Jackson, S.2    Seaman, M.3    Brown, K.4    Kempkes, B.5    Hibshoosh, H.6    Levine, B.7
  • 59
    • 32244442749 scopus 로고    scopus 로고
    • Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking
    • DOI 10.1242/jcs.02735
    • Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking. Zeng X, Overmeyer JH, Maltese WA, J Cell Sci 2006 119 259 270 10.1242/jcs.02735 16390869 (Pubitemid 43210695)
    • (2006) Journal of Cell Science , vol.119 , Issue.2 , pp. 259-270
    • Zeng, X.1    Overmeyer, J.H.2    Maltese, W.A.3
  • 60
    • 0035049961 scopus 로고    scopus 로고
    • Co-expression of multiple transgenes in mouse CNS: A comparison of strategies
    • DOI 10.1016/S1389-0344(01)00067-3, PII S1389034401000673
    • Co-expression of multiple transgenes in mouse CNS: a comparison of strategies. Jankowsky JL, Slunt HH, Ratovitski T, Jenkins NA, Copeland NG, Borchelt DR, Biomol Eng 2001 17 157 165 10.1016/S1389-0344(01)00067-3 11337275 (Pubitemid 32409891)
    • (2001) Biomolecular Engineering , vol.17 , Issue.6 , pp. 157-165
    • Jankowsky, J.L.1    Slunt, H.H.2    Ratovitski, T.3    Jenkins, N.A.4    Copeland, N.G.5    Borchelt, D.R.6
  • 61
    • 3042651851 scopus 로고    scopus 로고
    • APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1
    • DOI 10.1016/j.neurobiolaging.2003.09.008, PII S0197458003002367
    • APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1. Jankowsky JL, Slunt HH, Gonzales V, Jenkins NA, Copeland NG, Borchelt DR, Neurobiol Aging 2004 25 885 892 10.1016/j.neurobiolaging.2003.09. 008 15212842 (Pubitemid 38813168)
    • (2004) Neurobiology of Aging , vol.25 , Issue.7 , pp. 885-892
    • Jankowsky, J.L.1    Slunt, H.H.2    Gonzales, V.3    Jenkins, N.A.4    Copeland, N.G.5    Borchelt, D.R.6
  • 62
    • 0141672049 scopus 로고    scopus 로고
    • P38 MAP kinase is activated at early stages in Alzheimer's disease brain
    • DOI 10.1016/S0014-4886(03)00180-8
    • P38 MAP kinase is activated at early stages in Alzheimer's disease brain. Sun A, Liu M, Nguyen XV, Bing G, Exp Neurol 2003 183 394 405 10.1016/S0014-4886(03)00180-8 14552880 (Pubitemid 37205081)
    • (2003) Experimental Neurology , vol.183 , Issue.2 , pp. 394-405
    • Sun, A.1    Liu, M.2    Nguyen, X.V.3    Bing, G.4
  • 63
    • 84655165104 scopus 로고    scopus 로고
    • Histopathologic characterization of the BTBR mouse model of autistic-like behavior reveals selective changes in neurodevelopmental proteins and adult hippocampal neurogenesis
    • 10.1186/2040-2392-2-7 21575186
    • Histopathologic characterization of the BTBR mouse model of autistic-like behavior reveals selective changes in neurodevelopmental proteins and adult hippocampal neurogenesis. Stephenson DT, O'Neill SM, Narayan S, Tiwari A, Arnold E, Samaroo HD, Du F, Ring RH, Campbell B, Pletcher M, et al. Mol Autism 2011 2 7 10.1186/2040-2392-2-7 21575186
    • (2011) Mol Autism , vol.2 , pp. 7
    • Stephenson, D.T.1    O'Neill, S.M.2    Narayan, S.3    Tiwari, A.4    Arnold, E.5    Samaroo, H.D.6    Du, F.7    Ring, R.H.8    Campbell, B.9    Pletcher, M.10
  • 64
    • 59049086280 scopus 로고    scopus 로고
    • NG2 cells are distinct from neurogenic cells in the postnatal mouse subventricular zone
    • 10.1002/cne.21917 19058188
    • NG2 cells are distinct from neurogenic cells in the postnatal mouse subventricular zone. Komitova M, Zhu X, Serwanski DR, Nishiyama A, J Comp Neurol 2009 512 702 716 10.1002/cne.21917 19058188
    • (2009) J Comp Neurol , vol.512 , pp. 702-716
    • Komitova, M.1    Zhu, X.2    Serwanski, D.R.3    Nishiyama, A.4
  • 65
    • 34250186388 scopus 로고    scopus 로고
    • Isolation and culture of rat and mouse oligodendrocyte precursor cells
    • DOI 10.1038/nprot.2007.149, PII NPROT.2007.149
    • Isolation and culture of rat and mouse oligodendrocyte precursor cells. Chen Y, Balasubramaniyan V, Peng J, Hurlock EC, Tallquist M, Li J, Lu QR, Nat Protoc 2007 2 1044 1051 10.1038/nprot.2007.149 17546009 (Pubitemid 46901285)
    • (2007) Nature Protocols , vol.2 , Issue.5 , pp. 1044-1051
    • Chen, Y.1    Balasubramaniyan, V.2    Peng, J.3    Hurlock, E.C.4    Tallquist, M.5    Li, J.6    Lu, Q.R.7
  • 66
    • 0029075816 scopus 로고
    • Lines of murine oligodendroglial precursor cells immortalized by an activated neu tyrosine kinase show distinct degrees of interaction with axons in vitro and in vivo
    • 10.1111/j.1460-9568.1995.tb01115.x 7582098
    • Lines of murine oligodendroglial precursor cells immortalized by an activated neu tyrosine kinase show distinct degrees of interaction with axons in vitro and in vivo. Jung M, Kramer E, Grzenkowski M, Tang K, Blakemore W, Aguzzi A, Khazaie K, Chlichlia K, Von Blankenfeld G, Kettenmann H, et al. Eur J Neurosci 1995 7 1245 1265 10.1111/j.1460-9568.1995.tb01115.x 7582098
    • (1995) Eur J Neurosci , vol.7 , pp. 1245-1265
    • Jung, M.1    Kramer, E.2    Grzenkowski, M.3    Tang, K.4    Blakemore, W.5    Aguzzi, A.6    Khazaie, K.7    Chlichlia, K.8    Von Blankenfeld, G.9    Kettenmann, H.10
  • 68
    • 34447262102 scopus 로고    scopus 로고
    • The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation
    • DOI 10.1016/j.neuron.2007.06.029, PII S0896627307004631
    • The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. He Y, Dupree J, Wang J, Sandoval J, Li J, Liu H, Shi Y, Nave KA, Casaccia-Bonnefil P, Neuron 2007 55 217 230 10.1016/j.neuron.2007. 06.029 17640524 (Pubitemid 47048909)
    • (2007) Neuron , vol.55 , Issue.2 , pp. 217-230
    • He, Y.1    Dupree, J.2    Wang, J.3    Sandoval, J.4    Li, J.5    Liu, H.6    Shi, Y.7    Nave, K.A.8    Casaccia-Bonnefil, P.9
  • 69
    • 51349125658 scopus 로고    scopus 로고
    • In cultured oligodendrocytes the A/B-type hnRNP CBF-A accompanies MBP mRNA bound to mRNA trafficking sequences
    • 10.1091/mbc.E07-10-1083 18480411
    • In cultured oligodendrocytes the A/B-type hnRNP CBF-A accompanies MBP mRNA bound to mRNA trafficking sequences. Raju CS, Goritz C, Nord Y, Hermanson O, Lopez-Iglesias C, Visa N, Castelo-Branco G, Percipalle P, Mol Biol Cell 2008 19 3008 3019 10.1091/mbc.E07-10-1083 18480411
    • (2008) Mol Biol Cell , vol.19 , pp. 3008-3019
    • Raju, C.S.1    Goritz, C.2    Nord, Y.3    Hermanson, O.4    Lopez-Iglesias, C.5    Visa, N.6    Castelo-Branco, G.7    Percipalle, P.8
  • 70
    • 49949105827 scopus 로고    scopus 로고
    • The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells
    • 10.1038/cdd.2008.81 18551133
    • The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells. Li J, Ni M, Lee B, Barron E, Hinton DR, Lee AS, Cell Death Differ 2008 15 1460 1471 10.1038/cdd.2008.81 18551133
    • (2008) Cell Death Differ , vol.15 , pp. 1460-1471
    • Li, J.1    Ni, M.2    Lee, B.3    Barron, E.4    Hinton, D.R.5    Lee, A.S.6
  • 71
    • 33845742025 scopus 로고    scopus 로고
    • Thiamine deficiency induces endoplasmic reticulum stress in neurons
    • DOI 10.1016/j.neuroscience.2006.10.008, PII S0306452206013637
    • Thiamine deficiency induces endoplasmic reticulum stress in neurons. Wang X, Wang B, Fan Z, Shi X, Ke ZJ, Luo J, Neuroscience 2007 144 1045 1056 10.1016/j.neuroscience.2006.10.008 17137721 (Pubitemid 46013979)
    • (2007) Neuroscience , vol.144 , Issue.3 , pp. 1045-1056
    • Wang, X.1    Wang, B.2    Fan, Z.3    Shi, X.4    Ke, Z.-J.5    Luo, J.6
  • 72
    • 79954615141 scopus 로고    scopus 로고
    • Neuronal MCP-1 mediates microglia recruitment and neurodegeneration induced by the mild impairment of oxidative metabolism
    • 10.1111/j.1750-3639.2010.00445.x 21029241
    • Neuronal MCP-1 mediates microglia recruitment and neurodegeneration induced by the mild impairment of oxidative metabolism. Yang G, Meng Y, Li W, Yong Y, Fan Z, Ding H, Wei Y, Luo J, Ke ZJ, Brain Pathol 2011 21 279 297 10.1111/j.1750-3639.2010.00445.x 21029241
    • (2011) Brain Pathol , vol.21 , pp. 279-297
    • Yang, G.1    Meng, Y.2    Li, W.3    Yong, Y.4    Fan, Z.5    Ding, H.6    Wei, Y.7    Luo, J.8    Ke, Z.J.9
  • 73
    • 62249157748 scopus 로고    scopus 로고
    • Autophagy is required for preconditioning by the adenosine A1 receptor-selective agonist CCPA
    • 10.1007/s00395-009-0006-6 19242639
    • Autophagy is required for preconditioning by the adenosine A1 receptor-selective agonist CCPA. Yitzhaki S, Huang C, Liu W, Lee Y, Gustafsson AB, Mentzer RM Jr, Gottlieb RA, Basic Res Cardiol 2009 104 157 167 10.1007/s00395-009-0006-6 19242639
    • (2009) Basic Res Cardiol , vol.104 , pp. 157-167
    • Yitzhaki, S.1    Huang, C.2    Liu, W.3    Lee, Y.4    Gustafsson, A.B.5    Mentzer Jr., M.R.6    Gottlieb, R.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.