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Volumn 19, Issue 17-18, 2013, Pages 1889-1908

Depolarization alters phenotype, maintains plasticity of predifferentiated mesenchymal stem cells

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL SIGNALING; DEPOLARIZATION; GENE EXPRESSION; MAINTENANCE; MODULATION; MOLECULAR WEIGHT; STEM CELLS; TISSUE;

EID: 84881121970     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2012.0425.rev     Document Type: Article
Times cited : (74)

References (112)
  • 1
    • 37749033958 scopus 로고    scopus 로고
    • Human mesenchymal stem cells: From basic biology to clinical applications
    • Abdallah, B.M., and Kassem, M. Human mesenchymal stem cells: From basic biology to clinical applications. Gene Ther 15, 109, 2008
    • (2008) Gene Ther , vol.15 , pp. 109
    • Abdallah, B.M.1    Kassem, M.2
  • 2
    • 1542286220 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Clinical applications and biological characterization
    • Barry, F.P., and Murphy, J.M. Mesenchymal stem cells: Clinical applications and biological characterization. Int J Biochem Cell Biol 36, 568, 2004
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 568
    • Barry, F.P.1    Murphy, J.M.2
  • 3
    • 0036945050 scopus 로고    scopus 로고
    • Stem cells for myocardial regeneration
    • Orlic, D., Hill, J.M., and Arai, A.E. Stem cells for myocardial regeneration. Circ Res 91, 1092, 2002
    • (2002) Circ Res , vol.91 , pp. 1092
    • Orlic, D.1    Hill, J.M.2    Arai, A.E.3
  • 4
    • 77950551326 scopus 로고    scopus 로고
    • Mesenchymal stromal cells: Current understanding and clinical status
    • Salem, H.K., and Thiemermann, C. Mesenchymal stromal cells: Current understanding and clinical status. Stem Cells 28, 585, 2010
    • (2010) Stem Cells , vol.28 , pp. 585
    • Salem, H.K.1    Thiemermann, C.2
  • 9
    • 33745503500 scopus 로고    scopus 로고
    • Local irradiation not only induces homing of human mesenchymal stem cells at exposed sites but promotes their widespread engraftment to multiple organs: A study of their quantitative distribution after irradiation damage
    • François, S., Bensidhoum, M., Mouiseddine, M., Mazurier, C., Allenet, B., Semont, A., Frick, J., Saché, A., Bouchet, S., Thierry, D., Gourmelon, P., Gorin, N.C., and Chapel, A. Local irradiation not only induces homing of human mesenchymal stem cells at exposed sites but promotes their widespread engraftment to multiple organs: A study of their quantitative distribution after irradiation damage. Stem Cells 24, 1020, 2006
    • (2006) Stem Cells , vol.24 , pp. 1020
    • François, S.1    Bensidhoum, M.2    Mouiseddine, M.3    Mazurier, C.4    Allenet, B.5    Semont, A.6    Frick, J.7    Saché, A.8    Bouchet, S.9    Thierry, D.10    Gourmelon, P.11    Gorin, N.C.12    Chapel, A.13
  • 10
    • 0035010796 scopus 로고    scopus 로고
    • The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion
    • Gao, J., Dennis, J.E., Muzic, R.F., Lundberg, M., and Caplan, A.I. The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion. Cells Tissues Organs 169, 12, 2001
    • (2001) Cells Tissues Organs , vol.169 , pp. 12
    • Gao, J.1    Dennis, J.E.2    Muzic, R.F.3    Lundberg, M.4    Caplan, A.I.5
  • 12
    • 78951478823 scopus 로고    scopus 로고
    • Dedifferentiation transdifferentiation and reprogramming: Three routes to regeneration
    • Jopling, C., Boue, S., and Izpisua Belmonte, J.C. Dedifferentiation, transdifferentiation and reprogramming: Three routes to regeneration. Nat Rev Mol Cell Biol 12, 79, 2011
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 79
    • Jopling, C.1    Boue, S.2    Izpisua Belmonte, J.C.3
  • 13
    • 77950200829 scopus 로고    scopus 로고
    • Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
    • Jopling, C., Sleep, E., Raya, M., Marti, M., Raya, A., and Izpisua Belmonte, J.C. Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation. Nature 464, 606, 2010
    • (2010) Nature , vol.464 , pp. 606
    • Jopling, C.1    Sleep, E.2    Raya, M.3    Marti, M.4    Raya, A.5    Izpisua Belmonte, J.C.6
  • 18
    • 0031032050 scopus 로고    scopus 로고
    • Newt myotubes reenter the cell cycle by phosphorylation of the retinoblastoma protein
    • Tanaka, E.M., Gann, A.A., Gates, P.B., and Brockes, J.P. Newt myotubes reenter the cell cycle by phosphorylation of the retinoblastoma protein. J Cell Biol 136, 155, 1997
    • (1997) J Cell Biol , vol.136 , pp. 155
    • Tanaka, E.M.1    Gann, A.A.2    Gates, P.B.3    Brockes, J.P.4
  • 19
    • 33749060495 scopus 로고    scopus 로고
    • Identification and functional analysis of candidate genes regulating mesenchymal stem cell self-renewal and multipotency
    • Song, L., Webb, N.E., Song, Y., and Tuan, R.S. Identification and functional analysis of candidate genes regulating mesenchymal stem cell self-renewal and multipotency. Stem Cells 24, 1707, 2006
    • (2006) Stem Cells , vol.24 , pp. 1707
    • Song, L.1    Webb, N.E.2    Song, Y.3    Tuan, R.S.4
  • 21
    • 67649429784 scopus 로고    scopus 로고
    • Bioelectric mechanisms in regeneration: Unique aspects and future perspectives
    • Levin, M. Bioelectric mechanisms in regeneration: Unique aspects and future perspectives. Semin Cell Dev Biol 20, 543, 2009
    • (2009) Semin Cell Dev Biol , vol.20 , pp. 543
    • Levin, M.1
  • 22
    • 85101411508 scopus 로고    scopus 로고
    • Endogenous bioelectric signals as morphogenetic controls of development, regeneration, and neoplasm
    • In: Pullar, C.E., ed. Boca Raton, FL: CRC Press
    • Levin, M. Endogenous bioelectric signals as morphogenetic controls of development, regeneration, and neoplasm. In: Pullar, C.E., ed. The Physiology of Bioelectricity in Development, Tissue Regeneration, and Cancer. Boca Raton, FL: CRC Press, 2011, pp. 39-89
    • (2011) Physiology of Bioelectricity in Development, Tissue Regeneration, and Cancer , pp. 39-89
    • Levin, M.1
  • 23
    • 70449718851 scopus 로고    scopus 로고
    • Bioelectric controls of cell proliferation: Ion channels, membrane voltage and the cell cycle
    • Blackiston, D.J., McLaughlin, K.A., and Levin, M. Bioelectric controls of cell proliferation: Ion channels, membrane voltage and the cell cycle. Cell Cycle 8, 3527, 2009
    • (2009) Cell Cycle , vol.8 , pp. 3527
    • Blackiston, D.J.1    McLaughlin, K.A.2    Levin, M.3
  • 24
    • 70349623937 scopus 로고    scopus 로고
    • Role of membrane potential in the regulation of cell proliferation and differentiation
    • Sundelacruz, S., Levin, M., and Kaplan, D.L. Role of membrane potential in the regulation of cell proliferation and differentiation. Stem Cell Rev Rep 5, 231, 2009
    • (2009) Stem Cell Rev Rep , vol.5 , pp. 231
    • Sundelacruz, S.1    Levin, M.2    Kaplan, D.L.3
  • 25
    • 34249682669 scopus 로고    scopus 로고
    • Large-scale biophysics: Ion flows and regeneration
    • Levin, M. Large-scale biophysics: Ion flows and regeneration. Trends Cell Biol 17, 261, 2007
    • (2007) Trends Cell Biol , vol.17 , pp. 261
    • Levin, M.1
  • 26
    • 84857050462 scopus 로고    scopus 로고
    • Molecular bioelectricity in developmental biology: New tools and recent discoveries: Control of cell behavior and pattern formation by transmembrane potential gradients
    • Levin, M. Molecular bioelectricity in developmental biology: New tools and recent discoveries: Control of cell behavior and pattern formation by transmembrane potential gradients. Bioessays 34, 205, 2012
    • (2012) Bioessays , vol.34 , pp. 205
    • Levin, M.1
  • 27
    • 34248195467 scopus 로고    scopus 로고
    • H+ pump-dependent changes in membrane voltage are an early mechanism necessary and sufficient to induce Xenopus tail regeneration
    • Adams, D.S., Masi, A., and Levin, M. H+ pump-dependent changes in membrane voltage are an early mechanism necessary and sufficient to induce Xenopus tail regeneration. Development 134, 1323, 2007
    • (2007) Development , vol.134 , pp. 1323
    • Adams, D.S.1    Masi, A.2    Levin, M.3
  • 28
    • 0036783805 scopus 로고    scopus 로고
    • Skin flaps inhibit both the current of injury at the amputation surface and regeneration of that limb in newts
    • Altizer, A.M., Stewart, S.G., Albertson, B.K., and Borgens, R.B. Skin flaps inhibit both the current of injury at the amputation surface and regeneration of that limb in newts. J Exp Zool 293, 467, 2002
    • (2002) J Exp Zool , vol.293 , pp. 467
    • Altizer, A.M.1    Stewart, S.G.2    Albertson, B.K.3    Borgens, R.B.4
  • 29
    • 79251575597 scopus 로고    scopus 로고
    • A chemical genetics approach reveals H,K-ATPase-mediated membrane voltage is required for planarian head regeneration
    • Beane, W.S., Morokuma, J., Adams, D.S., and Levin, M. A chemical genetics approach reveals H,K-ATPase-mediated membrane voltage is required for planarian head regeneration. Chem Biol 18, 77, 2011
    • (2011) Chem Biol , vol.18 , pp. 77
    • Beane, W.S.1    Morokuma, J.2    Adams, D.S.3    Levin, M.4
  • 30
    • 0030587615 scopus 로고    scopus 로고
    • Reduction of the current of injury leaving the amputation inhibits limb regeneration in the red spotted newt
    • Jenkins, L.S., Duerstock, B.S., and Borgens, R.B. Reduction of the current of injury leaving the amputation inhibits limb regeneration in the red spotted newt. Dev Biol 178, 251, 1996
    • (1996) Dev Biol , vol.178 , pp. 251
    • Jenkins, L.S.1    Duerstock, B.S.2    Borgens, R.B.3
  • 31
    • 77957330469 scopus 로고    scopus 로고
    • Induction of vertebrate regeneration by a transient sodium current
    • Tseng, A.S., Beane, W.S., Lemire, J.M., Masi, A., and Levin, M. Induction of vertebrate regeneration by a transient sodium current. J Neurosci 30, 13192, 2010
    • (2010) J Neurosci , vol.30 , pp. 13192
    • Tseng, A.S.1    Beane, W.S.2    Lemire, J.M.3    Masi, A.4    Levin, M.5
  • 32
    • 83755225284 scopus 로고    scopus 로고
    • Transmembrane voltage potential conrols embryonic eye patterning in Xenopus laevis
    • Pai, V.P., Aw, S., Shomrat, T., Lemire, J.M., and Levin, M. Transmembrane voltage potential conrols embryonic eye patterning in Xenopus laevis. Development 139, 313, 2012
    • (2012) Development , vol.139 , pp. 313
    • Pai, V.P.1    Aw, S.2    Shomrat, T.3    Lemire, J.M.4    Levin, M.5
  • 33
    • 79960379493 scopus 로고    scopus 로고
    • V-ATPase- dependent ectodermal voltage and pH regionalization are required for craniofacial morphogenesis
    • Vandenberg, L.N., Morrie, R.D., and Adams, D.S. V-ATPase- dependent ectodermal voltage and pH regionalization are required for craniofacial morphogenesis. Dev Dyn 240, 1889, 2011
    • (2011) Dev Dyn , vol.240 , pp. 1889
    • Vandenberg, L.N.1    Morrie, R.D.2    Adams, D.S.3
  • 34
    • 3142654858 scopus 로고    scopus 로고
    • Membrane hyperpolarization triggers myogenin and myocyte enhancer factor-2 expression during human myoblast differentiation
    • Konig, S., Hinard, V., Arnaudeau, S., Holzer, N., Potter, G., Bader, C.R., and Bernheim, L. Membrane hyperpolarization triggers myogenin and myocyte enhancer factor-2 expression during human myoblast differentiation. J Biol Chem 279, 28187, 2004
    • (2004) J Biol Chem , vol.279 , pp. 28187
    • Konig, S.1    Hinard, V.2    Arnaudeau, S.3    Holzer, N.4    Potter, G.5    Bader, C.R.6    Bernheim, L.7
  • 37
    • 42149155503 scopus 로고    scopus 로고
    • Initiation of human myoblast differentiation via dephosphorylation of Kir2.1 K+ channels at tyrosine 242
    • Hinard, V., Belin, D., Konig, S., Bader, C.R., and Bernheim, L. Initiation of human myoblast differentiation via dephosphorylation of Kir2.1 K+ channels at tyrosine 242. Development 135, 859, 2008
    • (2008) Development , vol.135 , pp. 859
    • Hinard, V.1    Belin, D.2    Konig, S.3    Bader, C.R.4    Bernheim, L.5
  • 38
    • 33748770920 scopus 로고    scopus 로고
    • The calcineurin pathway links hyperpolarization (Kir2.1)- induced Ca2 + signals to human myoblast differentiation and fusion
    • Konig, S., Béguet, A., Bader, C.R., and Bernheim, L. The calcineurin pathway links hyperpolarization (Kir2.1)- induced Ca2 + signals to human myoblast differentiation and fusion. Development 133, 3107, 2006
    • (2006) Development , vol.133 , pp. 3107
    • Konig, S.1    Béguet, A.2    Bader, C.R.3    Bernheim, L.4
  • 40
    • 0029619246 scopus 로고
    • A novel inward-rectifying K+ current with a cell-cycle dependence governs the resting potential of mammalian neuroblastoma cells
    • Arcangeli, A., Bianchi, L., Becchetti, A., Faravelli, L., Coronnello, M., Mini, E., Olivotto, M., and Wanke, E. A novel inward-rectifying K+ current with a cell-cycle dependence governs the resting potential of mammalian neuroblastoma cells. J Physiol 489, 455, 1995
    • (1995) J Physiol , vol.489 , pp. 455
    • Arcangeli, A.1    Bianchi, L.2    Becchetti, A.3    Faravelli, L.4    Coronnello, M.5    Mini, E.6    Olivotto, M.7    Wanke, E.8
  • 42
    • 0031428009 scopus 로고    scopus 로고
    • HERG- and IRK-like inward rectifier currents are sequentially expressed during neuronal development of neural crest cells and their derivatives
    • Arcangeli, A., Rosati, B., Cherubini, A., Crociani, O., Fontana, L., Ziller, C., Wanke, E., and Olivotto, M. HERG- and IRK-like inward rectifier currents are sequentially expressed during neuronal development of neural crest cells and their derivatives. Eur J Neurosci 9, 2596, 1997
    • (1997) Eur J Neurosci , vol.9 , pp. 2596
    • Arcangeli, A.1    Rosati, B.2    Cherubini, A.3    Crociani, O.4    Fontana, L.5    Ziller, C.6    Wanke, E.7    Olivotto, M.8
  • 43
    • 0032815888 scopus 로고    scopus 로고
    • Modulation of HERG current and herg gene expression during retinoic acid treatment of human neuroblastoma cells: Potentiating effects of BDNF
    • Arcangeli, A., Rosati, B., Crociani, O., Cherubini, A., Fontana, L., Passani, B., Wanke, E., and Olivotto, M. Modulation of HERG current and herg gene expression during retinoic acid treatment of human neuroblastoma cells: Potentiating effects of BDNF. J Neurobiol 40, 214, 1999
    • (1999) J Neurobiol , vol.40 , pp. 214
    • Arcangeli, A.1    Rosati, B.2    Crociani, O.3    Cherubini, A.4    Fontana, L.5    Passani, B.6    Wanke, E.7    Olivotto, M.8
  • 44
    • 77952526649 scopus 로고    scopus 로고
    • Role of voltage-gated potassium channels in the fate determination of embryonic stem cells
    • Ng, S.Y., Chin, C.H., Lau, Y.T., Luo, J., Wong, C.K., Bian, Z.X., and Tsang, S.Y. Role of voltage-gated potassium channels in the fate determination of embryonic stem cells. J Cell Physiol 224, 165, 2010
    • (2010) J Cell Physiol , vol.224 , pp. 165
    • Ng, S.Y.1    Chin, C.H.2    Lau, Y.T.3    Luo, J.4    Wong, C.K.5    Bian, Z.X.6    Tsang, S.Y.7
  • 45
    • 56649117342 scopus 로고    scopus 로고
    • Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells
    • Sundelacruz, S., Levin, M., and Kaplan, D.L. Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells. PLoS One 3, e3737, 2008
    • (2008) PLoS One , vol.3
    • Sundelacruz, S.1    Levin, M.2    Kaplan, D.L.3
  • 48
    • 46749134798 scopus 로고    scopus 로고
    • Changes in the expression of CD106, osteogenic genes, and transcription factors involved in the osteogenic differentiation of human bone marrow mesenchymal stem cells
    • Liu, F., Akiyama, Y., Tai, S., Maruyama, K., Kawaguchi, Y., Muramatsu, K., and Yamaguchi, K. Changes in the expression of CD106, osteogenic genes, and transcription factors involved in the osteogenic differentiation of human bone marrow mesenchymal stem cells. J Bone Miner Metab 26, 312, 2008
    • (2008) J Bone Miner Metab , vol.26 , pp. 312
    • Liu, F.1    Akiyama, Y.2    Tai, S.3    Maruyama, K.4    Kawaguchi, Y.5    Muramatsu, K.6    Yamaguchi, K.7
  • 49
    • 78650056585 scopus 로고    scopus 로고
    • In vitro study of the effects of ELF electric fields on gene expression in human epidermal cells
    • Collard, J.F., Mertens, B., and Hinsenkamp, M. In vitro study of the effects of ELF electric fields on gene expression in human epidermal cells. Bioelectromagnetics 32, 28, 2011
    • (2011) Bioelectromagnetics , vol.32 , pp. 28
    • Collard, J.F.1    Mertens, B.2    Hinsenkamp, M.3
  • 50
    • 80755128893 scopus 로고    scopus 로고
    • Bone Morphogenic Protein - MRNA upregulation after exposure to low frequency electric field
    • Hinsenkamp, M., and Collard, J.F. Bone Morphogenic Protein - MRNA upregulation after exposure to low frequency electric field. Int Orthop 35, 1577, 2011
    • (2011) Int Orthop , vol.35 , pp. 1577
    • Hinsenkamp, M.1    Collard, J.F.2
  • 52
    • 77954704442 scopus 로고    scopus 로고
    • Effects of pulsed electromagnetic fields on human osteoblastlike cells (MG-63): A pilot study
    • Sollazzo, V., Palmieri, A., Pezzetti, F., Massari, L., and Carinci, F. Effects of pulsed electromagnetic fields on human osteoblastlike cells (MG-63): A pilot study. Clin Orthop Relat Res 468, 2260, 2010
    • (2010) Clin Orthop Relat Res , vol.468 , pp. 2260
    • Sollazzo, V.1    Palmieri, A.2    Pezzetti, F.3    Massari, L.4    Carinci, F.5
  • 53
    • 34948823819 scopus 로고    scopus 로고
    • Engineering adipose-like tissue in vitro and in vivo utilizing human bone marrow and adipose-derived mesenchymal stem cells with silk fibroin 3D scaffolds
    • Mauney, J.R., Nguyen, T., Gillen, K., Kirker-Head, C., Gimble, J.M., and Kaplan, D.L. Engineering adipose-like tissue in vitro and in vivo utilizing human bone marrow and adipose-derived mesenchymal stem cells with silk fibroin 3D scaffolds. Biomaterials 28, 5280, 2007
    • (2007) Biomaterials , vol.28 , pp. 5280
    • Mauney, J.R.1    Nguyen, T.2    Gillen, K.3    Kirker-Head, C.4    Gimble, J.M.5    Kaplan, D.L.6
  • 55
    • 33744966656 scopus 로고    scopus 로고
    • Osteogenesis by human mesenchymal stem cells cultured on silk biomaterials: Comparison of adenovirus mediated gene transfer and protein delivery of BMP-2
    • Meinel, L., Hofmann, S., Betz, O., Fajardo, R., Merkle, H.P., Langer, R., Evans, C.H., Vunjak-Novakovic, G., and Kaplan, D.L. Osteogenesis by human mesenchymal stem cells cultured on silk biomaterials: Comparison of adenovirus mediated gene transfer and protein delivery of BMP-2. Biomaterials 27, 4993, 2006
    • (2006) Biomaterials , vol.27 , pp. 4993
    • Meinel, L.1    Hofmann, S.2    Betz, O.3    Fajardo, R.4    Merkle, H.P.5    Langer, R.6    Evans, C.H.7    Vunjak-Novakovic, G.8    Kaplan, D.L.9
  • 56
    • 46249088370 scopus 로고    scopus 로고
    • Lumi: A pipeline for processing Illumina microarray
    • Du, P., Kibbe, W.A., and Lin, S.M. lumi: A pipeline for processing Illumina microarray. Bioinformatics 24, 1547, 2008
    • (2008) Bioinformatics , vol.24 , pp. 1547
    • Du, P.1    Kibbe, W.A.2    Lin, S.M.3
  • 57
    • 39149111937 scopus 로고    scopus 로고
    • Model-based variance-stabilizing transformation for Illumina microarray data
    • Lin, S.M., Du, P., Huber, W., and Kibbe, W.A. Model-based variance-stabilizing transformation for Illumina microarray data. Nucleic Acids Res 36, e11, 2008
    • (2008) Nucleic Acids Res , vol.36
    • Lin, S.M.1    Du, P.2    Huber, W.3    Kibbe, W.A.4
  • 58
    • 4544341015 scopus 로고    scopus 로고
    • Linear Models Empirical Bayes Methods For Assessing Differential Expression In Microarray Experiments
    • Article 3
    • Smyth, G.K. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3, Article 3, 2004
    • (2004) Stat Appl Genet Mol Biol , vol.3
    • Smyth, G.K.1
  • 60
    • 79960610118 scopus 로고    scopus 로고
    • Revigo summarizes and visualizes long lists of gene ontology terms
    • Supek, F., Bosnjak, M., Skunca, N., and Smuc, T. Revigo summarizes and visualizes long lists of gene ontology terms. PLoS One 6, e21800, 2011
    • (2011) PLoS One , vol.6
    • Supek, F.1    Bosnjak, M.2    Skunca, N.3    Smuc, T.4
  • 63
    • 4944257952 scopus 로고    scopus 로고
    • Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow
    • Song, L., and Tuan, R.S. Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow. FASEB J 18, 980, 2004
    • (2004) FASEB J , vol.18 , pp. 980
    • Song, L.1    Tuan, R.S.2
  • 64
    • 0033485750 scopus 로고    scopus 로고
    • Donor variation in the growth properties and osteogenic potential of human marrow stromal cells
    • Phinney, D.G., Kopen, G., Righter, W., Webster, S., Tremain, N., and Prockop, D.J. Donor variation in the growth properties and osteogenic potential of human marrow stromal cells. J Cell Biochem 75, 424, 1999
    • (1999) J Cell Biochem , vol.75 , pp. 424
    • Phinney, D.G.1    Kopen, G.2    Righter, W.3    Webster, S.4    Tremain, N.5    Prockop, D.J.6
  • 65
    • 34447283203 scopus 로고    scopus 로고
    • Donor variation and loss of multipotency during in vitro expansion of human mesenchymal stem cells for bone tissue engineering
    • Siddappa, R., Licht, R., van Blitterswijk, C., and de Boer, J. Donor variation and loss of multipotency during in vitro expansion of human mesenchymal stem cells for bone tissue engineering. J Orthop Res 25, 1029, 2007
    • (2007) J Orthop Res , vol.25 , pp. 1029
    • Siddappa, R.1    Licht, R.2    Van Blitterswijk, C.3    De Boer, J.4
  • 67
    • 0026718865 scopus 로고
    • Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures
    • Beresford, J.N., Bennett, J.H., Devlin, C., Leboy, P.S., and Owen, M.E. Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures. J Cell Sci 102, 341, 1992
    • (1992) J Cell Sci , vol.102 , pp. 341
    • Beresford, J.N.1    Bennett, J.H.2    Devlin, C.3    Leboy, P.S.4    Owen, M.E.5
  • 68
    • 0023276009 scopus 로고
    • Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: A comparative histomorphometric study
    • Burkhardt, R., Kettner, G., Böhm, W., Schmidmeier, M., Schlag, R., Frisch, B., Mallmann, B., Eisenmenger, W., and Gilg, T. Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: A comparative histomorphometric study. Bone 8, 157, 1987
    • (1987) Bone , vol.8 , pp. 157
    • Burkhardt, R.1    Kettner, G.2    Böhm, W.3    Schmidmeier, M.4    Schlag, R.5    Frisch, B.6    Mallmann, B.7    Eisenmenger, W.8    Gilg, T.9
  • 69
    • 0034737742 scopus 로고    scopus 로고
    • Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase
    • Jaiswal, R.K., Jaiswal, N., Bruder, S.P., Mbalaviele, G., Marshak, D.R., and Pittenger, M.F. Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase. J Biol Chem 275, 9645, 2000
    • (2000) J Biol Chem , vol.275 , pp. 9645
    • Jaiswal, R.K.1    Jaiswal, N.2    Bruder, S.P.3    Mbalaviele, G.4    Marshak, D.R.5    Pittenger, M.F.6
  • 71
    • 0036090467 scopus 로고    scopus 로고
    • Divergent effects of selective peroxisome proliferator-activated receptor-g2 ligands on adipocyte versus osteoblast differentiation
    • Lecka-Czernik, B., Moerman, E.J., Grant, D.F., Lehmann, J.M., Manolagas, S.C., and Jilka, R.L. Divergent effects of selective peroxisome proliferator-activated receptor-g2 ligands on adipocyte versus osteoblast differentiation. Endocrinology 143, 2376, 2002
    • (2002) Endocrinology , vol.143 , pp. 2376
    • Lecka-Czernik, B.1    Moerman, E.J.2    Grant, D.F.3    Lehmann, J.M.4    Manolagas, S.C.5    Jilka, R.L.6
  • 74
    • 33748374453 scopus 로고    scopus 로고
    • Stable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: Role of the BMP-4 gene
    • Bowers, R.R., Kim, J.W., Otto, T.C., and Lane, M.D. Stable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: Role of the BMP-4 gene. Proc Natl Acad Sci U S A 103, 13022, 2006
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 13022
    • Bowers, R.R.1    Kim, J.W.2    Otto, T.C.3    Lane, M.D.4
  • 75
    • 33847773447 scopus 로고    scopus 로고
    • A role for bone morphogenetic protein-4 in adipocyte development
    • Bowers, R.R., and Lane, M.D. A role for bone morphogenetic protein-4 in adipocyte development. Cell Cycle 6, 385, 2007
    • (2007) Cell Cycle , vol.6 , pp. 385
    • Bowers, R.R.1    Lane, M.D.2
  • 76
    • 0032514135 scopus 로고    scopus 로고
    • Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages
    • Chen, D., Ji, X., Harris, M.A., Feng, J.Q., Karsenty, G., Celeste, A.J., Rosen, V., Mundy, G.R., and Harris, S.E. Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages. J Cell Biol 142, 295, 1998
    • (1998) J Cell Biol , vol.142 , pp. 295
    • Chen, D.1    Ji, X.2    Harris, M.A.3    Feng, J.Q.4    Karsenty, G.5    Celeste, A.J.6    Rosen, V.7    Mundy, G.R.8    Harris, S.E.9
  • 78
    • 67649271549 scopus 로고    scopus 로고
    • A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells
    • Kang, Q., and He, T.C. A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells. Stem Cells Dev 18, 545, 2008
    • (2008) Stem Cells Dev , vol.18 , pp. 545
    • Kang, Q.1    He, T.C.2
  • 79
    • 0033341949 scopus 로고    scopus 로고
    • Extracellular matrix-associated bone morphogenetic proteins are essential for differentiation of murine osteoblastic cells in vitro
    • Suzawa, M., Takeuchi, Y., Fukumoto, S., Kato, S., Ueno, N., Miyazono, K., Matsumoto, T., and Fujita, T. Extracellular matrix-associated bone morphogenetic proteins are essential for differentiation of murine osteoblastic cells in vitro. Endocrinology 140, 2125, 1999
    • (1999) Endocrinology , vol.140 , pp. 2125
    • Suzawa, M.1    Takeuchi, Y.2    Fukumoto, S.3    Kato, S.4    Ueno, N.5    Miyazono, K.6    Matsumoto, T.7    Fujita, T.8
  • 80
    • 0030804095 scopus 로고    scopus 로고
    • Stimulatory effects of basic fibroblast growth factor and bone morphogenetic protein-2 on osteogenic differentiation of rat bone marrow- derived mesenchymal stem cells
    • Hanada, K., Dennis, J.E., and Caplan, A.I. Stimulatory effects of basic fibroblast growth factor and bone morphogenetic protein-2 on osteogenic differentiation of rat bone marrow- derived mesenchymal stem cells. J Bone Miner Res 12, 1606, 1997
    • (1997) J Bone Miner Res , vol.12 , pp. 1606
    • Hanada, K.1    Dennis, J.E.2    Caplan, A.I.3
  • 83
    • 0027227932 scopus 로고
    • Effect of basic fibroblast growth factor on the growth and differentiation of adult stromal bone marrow cells: Enhanced development of mineralized bone- like tissue in culture
    • Pitaru, S., Kotev-Emeth, S., Noff, D., Kaffuler, S., and Savion, N. Effect of basic fibroblast growth factor on the growth and differentiation of adult stromal bone marrow cells: Enhanced development of mineralized bone- like tissue in culture. J Bone Miner Res 8, 919, 1993
    • (1993) J Bone Miner Res , vol.8 , pp. 919
    • Pitaru, S.1    Kotev-Emeth, S.2    Noff, D.3    Kaffuler, S.4    Savion, N.5
  • 84
    • 32044467131 scopus 로고    scopus 로고
    • Insulin-like growth factor-I induces early osteoblast gene expression in human mesenchymal stem cells
    • Koch, H., Jadlowiec, J.A., and Campbell, P.G. Insulin-like growth factor-I induces early osteoblast gene expression in human mesenchymal stem cells. Stem Cells Dev 14, 621, 2005
    • (2005) Stem Cells Dev , vol.14 , pp. 621
    • Koch, H.1    Jadlowiec, J.A.2    Campbell, P.G.3
  • 85
    • 3242686718 scopus 로고    scopus 로고
    • Insulinlike growth factor-I stimulates both cell growth and lipogenesis during differentiation of human mesenchymal stem cells into adipocytes
    • Scavo, L.M., Karas, M., Murray, M., and Leroith, D. Insulinlike growth factor-I stimulates both cell growth and lipogenesis during differentiation of human mesenchymal stem cells into adipocytes. J Clin Endocrinol Metab 89, 3543, 2004
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3543
    • Scavo, L.M.1    Karas, M.2    Murray, M.3    Leroith, D.4
  • 86
    • 0033303803 scopus 로고    scopus 로고
    • Response of bipotential human marrow stromal cells to insulin-like growth factors: Effect on binding protein production, proliferation, and commitment to osteoblasts and adipocytes
    • Thomas, T., Gori, F., Spelsberg, T.C., Khosla, S., Riggs, B.L., and Conover, C.A. Response of bipotential human marrow stromal cells to insulin-like growth factors: Effect on binding protein production, proliferation, and commitment to osteoblasts and adipocytes. Endocrinology 140, 5036, 1999
    • (1999) Endocrinology , vol.140 , pp. 5036
    • Thomas, T.1    Gori, F.2    Spelsberg, T.C.3    Khosla, S.4    Riggs, B.L.5    Conover, C.A.6
  • 87
    • 24744462930 scopus 로고    scopus 로고
    • BMP-2 and insulin-like growth factor-I mediate osterix (Osx) expression in human mesenchymal stem cells via the MAPK and protein kinase D signaling pathways
    • Celil, A.B., and Campbell, P.G. BMP-2 and insulin-like growth factor-I mediate osterix (Osx) expression in human mesenchymal stem cells via the MAPK and protein kinase D signaling pathways. J Biol Chem 280, 31353, 2005
    • (2005) J Biol Chem , vol.280 , pp. 31353
    • Celil, A.B.1    Campbell, P.G.2
  • 88
    • 0037323398 scopus 로고    scopus 로고
    • Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator- activating receptor g during bone morphogenetic protein 2-induced adipogenesis
    • Hata, K., Nishimura, R., Ikeda, F., Yamashita, K., Matsubara, T., Nokubi, T., and Yoneda, T. Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator- activating receptor g during bone morphogenetic protein 2-induced adipogenesis. Mol Biol Cell 14, 545, 2003
    • (2003) Mol Biol Cell , vol.14 , pp. 545
    • Hata, K.1    Nishimura, R.2    Ikeda, F.3    Yamashita, K.4    Matsubara, T.5    Nokubi, T.6    Yoneda, T.7
  • 89
    • 0034740591 scopus 로고    scopus 로고
    • TGFb and BMP-2 activation of the OPN promoter: Roles of Smad- and Hox-binding elements
    • Hullinger, T.G., Pan, Q., Viswanathan, H.L., and Somerman, M.J. TGFb and BMP-2 activation of the OPN promoter: Roles of Smad- and Hox-binding elements. Exp Cell Res 262, 69, 2001
    • (2001) Exp Cell Res , vol.262 , pp. 69
    • Hullinger, T.G.1    Pan, Q.2    Viswanathan, H.L.3    Somerman, M.J.4
  • 91
    • 19444377293 scopus 로고    scopus 로고
    • Roles of KATP channels as metabolic sensors in acute metabolic changes
    • Miki, T., and Seino, S. Roles of KATP channels as metabolic sensors in acute metabolic changes. J Mol Cell Cardiol 38, 917, 2005
    • (2005) J Mol Cell Cardiol , vol.38 , pp. 917
    • Miki, T.1    Seino, S.2
  • 92
    • 33645322386 scopus 로고    scopus 로고
    • KATP channels as molecular sensors of cellular metabolism
    • Nichols, C.G. KATP channels as molecular sensors of cellular metabolism. Nature 440, 470, 2006
    • (2006) Nature , vol.440 , pp. 470
    • Nichols, C.G.1
  • 93
    • 35648945750 scopus 로고    scopus 로고
    • ATP-sensitive potassium channels: Metabolic sensing and cardioprotection
    • Zingman, L.V., Alekseev, A.E., Hodgson-Zingman, D.M., and Terzic, A. ATP-sensitive potassium channels: Metabolic sensing and cardioprotection. J Appl Physiol 103, 1888, 2007
    • (2007) J Appl Physiol , vol.103 , pp. 1888
    • Zingman, L.V.1    Alekseev, A.E.2    Hodgson-Zingman, D.M.3    Terzic, A.4
  • 94
    • 80052902250 scopus 로고    scopus 로고
    • KATP channels in mesenchymal stromal stem cells: Strong up-regulation of Kir6.2 subunits upon osteogenic differentiation
    • Diehlmann, A., Bork, S., Saffrich, R., Veh, R.W., Wagner, W., and Derst, C. KATP channels in mesenchymal stromal stem cells: Strong up-regulation of Kir6.2 subunits upon osteogenic differentiation. Tissue Cell 43, 331, 2011
    • (2011) Tissue Cell , vol.43 , pp. 331
    • Diehlmann, A.1    Bork, S.2    Saffrich, R.3    Veh, R.W.4    Wagner, W.5    Derst, C.6
  • 95
    • 19644363859 scopus 로고    scopus 로고
    • A possible role for membrane depolarization in epithelial wound healing
    • Chifflet, S., Hernandez, J.A., and Grasso, S. A possible role for membrane depolarization in epithelial wound healing. Am J Physiol Cell Physiol 288, C1420, 2005
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Chifflet, S.1    Hernandez, J.A.2    Grasso, S.3
  • 96
    • 0037229620 scopus 로고    scopus 로고
    • Nonspecific depolarization of the plasma membrane potential induces cytoskeletal modifications of bovine corneal endothelial cells in culture
    • Chifflet, S., Hernandez, J.A., Grasso, S., and Cirillo, A. Nonspecific depolarization of the plasma membrane potential induces cytoskeletal modifications of bovine corneal endothelial cells in culture. Exp Cell Res 282, 1, 2003
    • (2003) Exp Cell Res , vol.282 , pp. 1
    • Chifflet, S.1    Hernandez, J.A.2    Grasso, S.3    Cirillo, A.4
  • 97
    • 73249150757 scopus 로고    scopus 로고
    • Hyperpolarization of the plasma membrane potential provokes reorganization of the actin cytoskeleton and increases the stability of adherens junctions in bovine corneal endothelial cells in culture
    • Nin, V., Hernandez, J.A., and Chifflet, S. Hyperpolarization of the plasma membrane potential provokes reorganization of the actin cytoskeleton and increases the stability of adherens junctions in bovine corneal endothelial cells in culture. Cell Motil Cytoskeleton 66, 1087, 2009
    • (2009) Cell Motil Cytoskeleton , vol.66 , pp. 1087
    • Nin, V.1    Hernandez, J.A.2    Chifflet, S.3
  • 98
    • 33751334377 scopus 로고    scopus 로고
    • Complex functional interaction between integrin receptors and ion channels
    • Arcangeli, A., and Becchetti, A. Complex functional interaction between integrin receptors and ion channels. Trends Cell Biol 16, 631, 2006
    • (2006) Trends Cell Biol , vol.16 , pp. 631
    • Arcangeli, A.1    Becchetti, A.2
  • 99
    • 84858322269 scopus 로고    scopus 로고
    • The plasma membrane potential and the organization of the actin cytoskeleton of epithelial cells
    • Chifflet, S., and Hernandez, J.A. The plasma membrane potential and the organization of the actin cytoskeleton of epithelial cells. Int J Cell Biol 2012, 121424, 2012
    • (2012) Int J Cell Biol , vol.2012 , pp. 121424
    • Chifflet, S.1    Hernandez, J.A.2
  • 101
    • 33846994060 scopus 로고    scopus 로고
    • Exon silencing by UAGG motifs in response to neuronal excitation
    • An, P., and Grabowski, P.J. Exon silencing by UAGG motifs in response to neuronal excitation. PLoS Biol 5, e36, 2007
    • (2007) PLoS Biol , vol.5
    • An, P.1    Grabowski, P.J.2
  • 102
    • 33846989782 scopus 로고    scopus 로고
    • Depolarization and CaM kinase IV modulate NMDA receptor splicing through two essential RNA elements
    • Lee, J.A., Xing, Y., Nguyen, D., Xie, J., Lee, C.J., and Black, D.L. Depolarization and CaM kinase IV modulate NMDA receptor splicing through two essential RNA elements. PLoS Biol 5, e40, 2007
    • (2007) PLoS Biol , vol.5
    • Lee, J.A.1    Xing, Y.2    Nguyen, D.3    Xie, J.4    Lee, C.J.5    Black, D.L.6
  • 103
    • 0033005133 scopus 로고    scopus 로고
    • Depolarization regulates cyclin D1 degradation and neuronal apoptosis: A hypothesis about the role of the ubiquitin/proteasome signalling pathway
    • Boutillier, A.L. Depolarization regulates cyclin D1 degradation and neuronal apoptosis: A hypothesis about the role of the ubiquitin/proteasome signalling pathway. Eur J Neurosci 11, 441, 1999
    • (1999) Eur J Neurosci , vol.11 , pp. 441
    • Boutillier, A.L.1
  • 104
    • 33744548557 scopus 로고    scopus 로고
    • Temporally and spatially coordinated roles for Rho, Rac, Cdc42 and their effectors in growth cone guidance by a physiological electric field
    • Rajnicek, A.M., Foubister, L.E., and McCaig, C.D. Temporally and spatially coordinated roles for Rho, Rac, Cdc42 and their effectors in growth cone guidance by a physiological electric field. J Cell Sci 119, 1723, 2006
    • (2006) J Cell Sci , vol.119 , pp. 1723
    • Rajnicek, A.M.1    Foubister, L.E.2    McCaig, C.D.3
  • 105
    • 67650492029 scopus 로고    scopus 로고
    • Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2 + release in smooth muscle
    • Liu, Q.H., Zheng, Y.M., Korde, A.S., Yadav, V.R., Rathore, R., Wess, J., and Wang, Y.X. Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2 + release in smooth muscle. Proc Natl Acad Sci U S A 106, 11418, 2009
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 11418
    • Liu, Q.H.1    Zheng, Y.M.2    Korde, A.S.3    Yadav, V.R.4    Rathore, R.5    Wess, J.6    Wang, Y.X.7
  • 107
    • 0141522973 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha increases cytosolic calcium responses to AMPA and KCl in primary cultures of rat hippocampal neurons
    • De, A., Krueger, J.M., and Simasko, S.M. Tumor necrosis factor alpha increases cytosolic calcium responses to AMPA and KCl in primary cultures of rat hippocampal neurons. Brain Res 981, 133, 2003
    • (2003) Brain Res , vol.981 , pp. 133
    • Krueger, J.M.1    Simasko, S.M.2
  • 108
  • 109
    • 0030453517 scopus 로고    scopus 로고
    • Tumour necrosis factoralpha increases intracellular Ca2 + and induces a depolarization in cultured astroglial cells
    • Koller, H., Thiem, K., and Siebler, M. Tumour necrosis factoralpha increases intracellular Ca2 + and induces a depolarization in cultured astroglial cells. Brain 119, 2021, 1996
    • (1996) Brain , vol.119 , pp. 2021
    • Koller, H.1    Thiem, K.2    Siebler, M.3
  • 110
    • 77955659695 scopus 로고    scopus 로고
    • Wnt11 patterns a myocardial electrical gradient through regulation of the L-type Ca2 + channel
    • Panáková, D., Werdich, A.A., and MacRae, C.A. Wnt11 patterns a myocardial electrical gradient through regulation of the L-type Ca2 + channel. Nature 466, 874, 2010
    • (2010) Nature , vol.466 , pp. 874
    • Panáková, D.1    Werdich, A.A.2    MacRae, C.A.3
  • 112
    • 33644828002 scopus 로고    scopus 로고
    • A Wnt canon orchestrating osteoblastogenesis
    • Hartmann, C. A Wnt canon orchestrating osteoblastogenesis. Trends Cell Biol 16, 151, 2006.
    • (2006) Trends Cell Biol , vol.16 , pp. 151
    • Hartmann, C.1


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