메뉴 건너뛰기




Volumn 18, Issue 4, 2009, Pages 545-558

A Comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells

(28)  Kang, Quan a,b   Song, Wen Xin a,b   Luo, Qing a,b   Tang, Ni a   Luo, Jinyong a,b   Luo, Xiaoji a,b   Chen, Jin a,b   Bi, Yang a,b   He, Bai Cheng a,b   Park, Jong Kyung a,c   Jiang, Wei b   Tang, Yi d   Huang, Jiayi a,b   Su, Yuxi a,b   Zhu, Gao Hui a,b   He, Yun a,b   Yin, Hong b   Hu, Zhenming a   Wang, Yi a,b   Chen, Liang a   more..


Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 6; BONE MORPHOGENETIC PROTEIN 9; MYOD PROTEIN; OSTEOGENIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9;

EID: 67649271549     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2008.0130     Document Type: Article
Times cited : (347)

References (73)
  • 1
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for non- hematopoietic tissues
    • Prockop DJ. (1997). Marrow stromal cells as stem cells for non- hematopoietic tissues. Science 276:71-74.
    • (1997) Science , vol.276 , pp. 71-74
    • Prockop, D.J.1
  • 2
    • 0032416022 scopus 로고    scopus 로고
    • Bone stem cells
    • Aubin JE. (1998). Bone stem cells. J Cell Biochem Suppl 31:73-82.
    • (1998) J Cell Biochem , Issue.SUPPL. 31 , pp. 73-82
    • Aubin, J.E.1
  • 4
    • 0034285013 scopus 로고    scopus 로고
    • The osteoblast: A sophisticated fibroblast under central surveillance
    • Ducy P, T Schinke and G Karsenty. (2000). The osteoblast: a sophisticated fibroblast under central surveillance. Science 289:1501-1504.
    • (2000) Science , vol.289 , pp. 1501-1504
    • Ducy, P.1    Schinke, T.2    Karsenty, G.3
  • 7
    • 20444429578 scopus 로고    scopus 로고
    • Adult mesenchymal stem cells: Characterization, differentiation, and application in cell and gene therapy
    • Baksh D, L Song and RS Tuan. (2004). Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy. J Cell Mol Med 8:301-316.
    • (2004) J Cell Mol Med , vol.8 , pp. 301-316
    • Baksh, D.1    Song, L.2    Tuan, R.S.3
  • 8
    • 1542286220 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Clinical applications and biological characterization
    • Barry FP and JM Murphy. (2004). Mesenchymal stem cells: clinical applications and biological characterization. Int J Biochem Cell Biol 36:568-584.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 568-584
    • Barry, F.P.1    Murphy, J.M.2
  • 10
    • 17144384449 scopus 로고    scopus 로고
    • Tumorigenic heterogeneity in cancer stem cells evolved from long-term cultures of telomerase- immortalized human mesenchymal stem cells
    • Burns JS, BM Abdallah, P Guldberg, J Rygaard, HD Schroder and M Kassem. (2005). Tumorigenic heterogeneity in cancer stem cells evolved from long-term cultures of telomerase- immortalized human mesenchymal stem cells. Cancer Res 65:3126-3135.
    • (2005) Cancer Res , vol.65 , pp. 3126-3135
    • Burns, J.S.1    Abdallah, B.M.2    Guldberg, P.3    Rygaard, J.4    Schroder, H.D.5    Kassem, M.6
  • 12
    • 5444243641 scopus 로고    scopus 로고
    • The canonical Wnt pathway in early mammalian embryogenesis and stem cell maintenance/differentiation
    • Wang J and A Wynshaw-Boris. (2004). The canonical Wnt pathway in early mammalian embryogenesis and stem cell maintenance/differentiation. Curr Opin Genet Dev 14:533-539.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 533-539
    • Wang, J.1    Wynshaw-Boris, A.2
  • 13
    • 7744241519 scopus 로고    scopus 로고
    • Wnt signaling and the regulation of stem cell function
    • Kleber M and L Sommer. (2004). Wnt signaling and the regulation of stem cell function. Curr Opin Cell Biol 16:681-687
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 681-687
    • Kleber, M.1    Sommer, L.2
  • 14
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • Reya T and H Clevers. (2005). Wnt signalling in stem cells and cancer. Nature 434:843-850.
    • (2005) Nature , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 17
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y and J Massague. (2003). Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113:685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 18
    • 0037204990 scopus 로고    scopus 로고
    • Signal transduction by the TGF-beta superfamily
    • Attisano L and JL Wrana. (2002). Signal transduction by the TGF-beta superfamily. Science 296:1646-1647.
    • (2002) Science , vol.296 , pp. 1646-1647
    • Attisano, L.1    Wrana, J.L.2
  • 19
    • 24644507896 scopus 로고    scopus 로고
    • The disparate role of BMP in stem cell biology
    • Varga AC and JL Wrana. (2005). The disparate role of BMP in stem cell biology. Oncogene 24:5713-5721.
    • (2005) Oncogene , vol.24 , pp. 5713-5721
    • Varga, A.C.1    Wrana, J.L.2
  • 20
    • 23244432429 scopus 로고    scopus 로고
    • BMP signaling and stem cell regulation
    • Zhang J and L Li. (2005). BMP signaling and stem cell regulation. Dev Biol 284:1-11.
    • (2005) Dev Biol , vol.284 , pp. 1-11
    • Zhang, J.1    Li, L.2
  • 21
    • 0029737070 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
    • Hogan BL. (1996). Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev 10:1580-1594.
    • (1996) Genes Dev , vol.10 , pp. 1580-1594
    • Hogan, B.L.1
  • 23
    • 0037250476 scopus 로고    scopus 로고
    • Consequences of knocking out BMP signaling in the mouse
    • Zhao GQ. (2003). Consequences of knocking out BMP signaling in the mouse. Genesis 35:43-56.
    • (2003) Genesis , vol.35 , pp. 43-56
    • Zhao, G.Q.1
  • 24
    • 34250019537 scopus 로고
    • Bone: Formation by autoinduction
    • Urist MR. (1965). Bone: formation by autoinduction. Science 150:893-899.
    • (1965) Science , vol.150 , pp. 893-899
    • Urist, M.R.1
  • 25
    • 0031909665 scopus 로고    scopus 로고
    • Role of morphogenetic proteins in skeletal tissue engineering and regeneration
    • Reddi AH. (1998). Role of morphogenetic proteins in skeletal tissue engineering and regeneration. Nat Biotechnol 16:247-252.
    • (1998) Nat Biotechnol , vol.16 , pp. 247-252
    • Reddi, A.H.1
  • 26
    • 0034128748 scopus 로고    scopus 로고
    • The family of bone morphoge- netic proteins
    • Ducy P and G Karsenty. (2000). The family of bone morphoge- netic proteins. Kidney Int 57:2207-2214.
    • (2000) Kidney Int , vol.57 , pp. 2207-2214
    • Ducy, P.1    Karsenty, G.2
  • 31
    • 3543041812 scopus 로고    scopus 로고
    • Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells
    • Peng Y, Q Kang, Q Luo, W Jiang, W Si, BA Liu, HH Luu, JK Park, X Li, J Luo, AG Montag, RC Haydon and TC He. (2004). Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells. J Biol Chem 279:32941-32949.
    • (2004) J Biol Chem , vol.279 , pp. 32941-32949
    • Peng, Y.1    Kang, Q.2    Luo, Q.3    Jiang, W.4    Si, W.5    Liu, B.A.6    Luu, H.H.7    Park, J.K.8    Li, X.9    Luo, J.10    Montag, A.G.11    Haydon, R.C.12    He, T.C.13
  • 32
    • 19944427451 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF) is regulated by Wnt and bone mor- phogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells
    • Luo Q, Q Kang, W Si, W Jiang, JK Park, Y Peng, X Li, HH Luu, J Luo, AG Montag, RC Haydon and TC He. (2004). Connective tissue growth factor (CTGF) is regulated by Wnt and bone mor- phogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells. J Biol Chem 279:55958-55968.
    • (2004) J Biol Chem , vol.279 , pp. 55958-55968
    • Luo, Q.1    Kang, Q.2    Si, W.3    Jiang, W.4    Park, J.K.5    Peng, Y.6    Li, X.7    Luu, H.H.8    Luo, J.9    Montag, A.G.10    Haydon, R.C.11    He, T.C.12
  • 34
    • 0034957648 scopus 로고    scopus 로고
    • Human BMP-7/ OP-1 induces the growth and differentiation of adipocytes and osteoblasts in bone marrow stromal cell cultures
    • Chen TL, WJ Shen and FB Kraemer. (2001). Human BMP-7/ OP-1 induces the growth and differentiation of adipocytes and osteoblasts in bone marrow stromal cell cultures. J Cell Biochem 82:187-199.
    • (2001) J Cell Biochem , vol.82 , pp. 187-199
    • Chen, T.L.1    Shen, W.J.2    Kraemer, F.B.3
  • 35
    • 0029128268 scopus 로고
    • Bone morphogenetic proteins inhibit adi- pocyte differentiation by bone marrow stromal cells
    • Gimble JM, C Morgan, K Kelly, X Wu, V Dandapani, CS Wang and V Rosen. (1995). Bone morphogenetic proteins inhibit adi- pocyte differentiation by bone marrow stromal cells. J Cell Biochem 58:393-402.
    • (1995) J Cell Biochem , vol.58 , pp. 393-402
    • Gimble, J.M.1    Morgan, C.2    Kelly, K.3    Wu, X.4    Dandapani, V.5    Wang, C.S.6    Rosen, V.7
  • 36
    • 0034011315 scopus 로고    scopus 로고
    • Patterns of gene expression associated with BMP-2-induced osteoblast and adipocyte differentiation of mesenchymal progenitor cell 3T3-F442A
    • In Process Citation
    • Ji X, D Chen, C Xu, SE Harris, GR Mundy and T Yoneda. (2000). Patterns of gene expression associated with BMP-2-induced osteoblast and adipocyte differentiation of mesenchymal progenitor cell 3T3-F442A [In Process Citation]. J Bone Miner Metab 18:132-139.
    • (2000) J Bone Miner Metab , vol.18 , pp. 132-139
    • Ji, X.1    Chen, D.2    Xu, C.3    Harris, S.E.4    Mundy, G.R.5    Yoneda, T.6
  • 37
    • 0034705835 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 stimulates adipogenic differentiation of mesenchymal precursor cells in synergy with BL 49653 (rosiglitazone)
    • Sottile V and K Seuwen. (2000). Bone morphogenetic protein-2 stimulates adipogenic differentiation of mesenchymal precursor cells in synergy with BL 49653 (rosiglitazone). FEBS Lett 475:201-204.
    • (2000) FEBS Lett , vol.475 , pp. 201-204
    • Sottile, V.1    Seuwen, K.2
  • 38
    • 0034141943 scopus 로고    scopus 로고
    • Bmp-4 requires the presence of the digits to initiate programmed cell death in limb interdigital tissues
    • Tang MK, AK Leung, WH Kwong, PH Chow, JY Chan, V Ngo- Muller, M Li and KK Lee. (2000). Bmp-4 requires the presence of the digits to initiate programmed cell death in limb interdigital tissues. Dev Biol 218:89-98.
    • (2000) Dev Biol , vol.218 , pp. 89-98
    • Tang, M.K.1    Leung, A.K.2    Kwong, W.H.3    Chow, P.H.4    Chan, J.Y.5    Ngo- Muller, V.6    Li, M.7    Lee, K.K.8
  • 39
    • 33748374453 scopus 로고    scopus 로고
    • Stable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: Role of the BMP-4 gene
    • Bowers RR, JW Kim, TC Otto and MD Lane. (2006). Stable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: Role of the BMP-4 gene. Proc Natl Acad Sci USA 103:13022-13027.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13022-13027
    • Bowers, R.R.1    Kim, J.W.2    Otto, T.C.3    Lane, M.D.4
  • 40
    • 0027185702 scopus 로고
    • Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells
    • Wang EA, DI Israel, S Kelly and DP Luxenberg. (1993). Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells. Growth Factors 9:57-71.
    • (1993) Growth Factors , vol.9 , pp. 57-71
    • Wang, E.A.1    Israel, D.I.2    Kelly, S.3    Luxenberg, D.P.4
  • 41
    • 33745727603 scopus 로고    scopus 로고
    • Effect of bone morphogenetic protein-4 (BMP-4) on adipocyte differentiation from mouse embryonic stem cells
    • Taha MF, MR Valojerdi and SJ Mowla. (2006). Effect of bone morphogenetic protein-4 (BMP-4) on adipocyte differentiation from mouse embryonic stem cells. Anat Histol Embryol 35:271-278.
    • (2006) Anat Histol Embryol , vol.35 , pp. 271-278
    • Taha, M.F.1    Valojerdi, M.R.2    Mowla, S.J.3
  • 42
    • 14644429806 scopus 로고    scopus 로고
    • Induction of chondro-, osteo- and adipogenesis in embryonic stem cells by bone morphogenetic protein-2: Effect of cofactors on differentiating lineages
    • zur Nieden NI, G Kempka, DE Rancourt and HJ Ahr. (2005). Induction of chondro-, osteo- and adipogenesis in embryonic stem cells by bone morphogenetic protein-2: effect of cofactors on differentiating lineages. BMC Dev Biol 5:1.
    • (2005) BMC Dev Biol , vol.5 , pp. 1
    • zur Nieden, N.I.1    Kempka, G.2    Rancourt, D.E.3    Ahr, H.J.4
  • 43
    • 14844334826 scopus 로고    scopus 로고
    • Dual-regulated expression of C/EBP-alpha and BMP-2 enables differential differentiation of C2C12 cells into adipocytes and osteoblasts
    • Fux C, B Mitta, BP Kramer and M Fussenegger. (2004). Dual-regulated expression of C/EBP-alpha and BMP-2 enables differential differentiation of C2C12 cells into adipocytes and osteoblasts. Nucleic Acids Res 32:e1.
    • (2004) Nucleic Acids Res , vol.32
    • Fux, C.1    Mitta, B.2    Kramer, B.P.3    Fussenegger, M.4
  • 44
    • 0033995295 scopus 로고    scopus 로고
    • Osteogenesis coordinated in C3H10T1 /2 cells by adipogenesis-dependent BMP-2 expression system
    • Mie M, H Ohgushi, Y Yanagida, T Haruyama, E Kobatake and M Aizawa. (2000). Osteogenesis coordinated in C3H10T1 /2 cells by adipogenesis-dependent BMP-2 expression system. Tissue Eng 6:9-18.
    • (2000) Tissue Eng , vol.6 , pp. 9-18
    • Mie, M.1    Ohgushi, H.2    Yanagida, Y.3    Haruyama, T.4    Kobatake, E.5    Aizawa, M.6
  • 45
    • 0030056920 scopus 로고    scopus 로고
    • Human oste- ogenic protein-1 induces chondroblastic, osteoblastic, and/or adipocytic differentiation of clonal murine target cells
    • Asahina I, TK Sampath and PV Hauschka. (1996). Human oste- ogenic protein-1 induces chondroblastic, osteoblastic, and/or adipocytic differentiation of clonal murine target cells. Exp Cell Res 222:38-47.
    • (1996) Exp Cell Res , vol.222 , pp. 38-47
    • Asahina, I.1    Sampath, T.K.2    Hauschka, P.V.3
  • 46
    • 0027721063 scopus 로고
    • Expression of human bone morphogenetic proteins-2 or -4 in murine mesenchymal progenitor C3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineages
    • Ahrens M, T Ankenbauer, D Schroder, A Hollnagel, H Mayer and G Gross. (1993). Expression of human bone morphogenetic proteins-2 or -4 in murine mesenchymal progenitor C3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineages. DNA Cell Biol 12:871-880.
    • (1993) DNA Cell Biol , vol.12 , pp. 871-880
    • Ahrens, M.1    Ankenbauer, T.2    Schroder, D.3    Hollnagel, A.4    Mayer, H.5    Gross, G.6
  • 47
    • 0015752438 scopus 로고
    • Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division
    • Reznikoff CA, DW Brankow and C Heidelberger. (1973). Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division. Cancer Res 33:3231-3238.
    • (1973) Cancer Res , vol.33 , pp. 3231-3238
    • Reznikoff, C.A.1    Brankow, D.W.2    Heidelberger, C.3
  • 50
    • 34250378403 scopus 로고    scopus 로고
    • A protocol for rapid generation of recombinant adenoviruses using the AdEasy system. Nat Protoc 2:1236-1247
    • A protocol for rapid generation of recombinant adenoviruses using the AdEasy system. Nat Protoc 2:1236-1247
  • 52
    • 0033615352 scopus 로고    scopus 로고
    • PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
    • He TC, TA Chan, B Vogelstein and KW Kinzler. (1999). PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell 99:335-345.
    • (1999) Cell , vol.99 , pp. 335-345
    • He, T.C.1    Chan, T.A.2    Vogelstein, B.3    Kinzler, K.W.4
  • 55
    • 0141516375 scopus 로고    scopus 로고
    • Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat
    • Li JZ, H Li, T Sasaki, D Holman, B Beres, RJ Dumont, DD Pittman, GR Hankins and GA Helm. (2003). Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat. Gene Ther 10:1735-1743.
    • (2003) Gene Ther , vol.10 , pp. 1735-1743
    • Li, J.Z.1    Li, H.2    Sasaki, T.3    Holman, D.4    Beres, B.5    Dumont, R.J.6    Pittman, D.D.7    Hankins, G.R.8    Helm, G.A.9
  • 56
    • 0015137446 scopus 로고
    • Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies
    • Meunier P, J Aaron, C Edouard and G Vignon. (1971). Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies. Clin Orthop Relat Res 80:147-154.
    • (1971) Clin Orthop Relat Res , vol.80 , pp. 147-154
    • Meunier, P.1    Aaron, J.2    Edouard, C.3    Vignon, G.4
  • 57
    • 0023276009 scopus 로고
    • Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: A comparative histomorphometric study
    • Burkhardt R, G Kettner, W Bohm, M Schmidmeier, R Schlag, B Frisch, B Mallmann, W Eisenmenger and T Gilg. (1987). Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: a comparative histomorphometric study. Bone 8:157-164.
    • (1987) Bone , vol.8 , pp. 157-164
    • Burkhardt, R.1    Kettner, G.2    Bohm, W.3    Schmidmeier, M.4    Schlag, R.5    Frisch, B.6    Mallmann, B.7    Eisenmenger, W.8    Gilg, T.9
  • 58
    • 0024989037 scopus 로고
    • Variations of fat tissue fraction in abnormal human bone marrow depend both on size and number of adi- pocytes: A stereologic study
    • Rozman C, JC Reverter, E Feliu, L Berga, M Rozman and C Climent. (1990). Variations of fat tissue fraction in abnormal human bone marrow depend both on size and number of adi- pocytes: a stereologic study. Blood 76:892-895.
    • (1990) Blood , vol.76 , pp. 892-895
    • Rozman, C.1    Reverter, J.C.2    Feliu, E.3    Berga, L.4    Rozman, M.5    Climent, C.6
  • 60
    • 0036724870 scopus 로고    scopus 로고
    • Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis
    • Verma S, JH Rajaratnam, J Denton, JA Hoyland and RJ Byers. (2002). Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis. J Clin Pathol 55:693-698.
    • (2002) J Clin Pathol , vol.55 , pp. 693-698
    • Verma, S.1    Rajaratnam, J.H.2    Denton, J.3    Hoyland, J.A.4    Byers, R.J.5
  • 61
    • 0034842784 scopus 로고    scopus 로고
    • Justesen J, K Stenderup, EN Ebbesen, L Mosekilde, T Steiniche and M Kassem. (2001). Adipocyte tissue in bone marrow is increased with aging and in patients with osteoporosis. Biogerontology 2:165-171.
    • Justesen J, K Stenderup, EN Ebbesen, L Mosekilde, T Steiniche and M Kassem. (2001). Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis. Biogerontology 2:165-171.
  • 62
    • 2342613539 scopus 로고    scopus 로고
    • Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications
    • Nuttall ME and JM Gimble. (2004). Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications. Curr Opin Pharmacol 4:290-294.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 290-294
    • Nuttall, M.E.1    Gimble, J.M.2
  • 63
    • 13844257282 scopus 로고    scopus 로고
    • Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: The role of PPAR-gamma2 transcription factor and TGF-beta/BMP signaling pathways
    • Moerman EJ, K Teng, DA Lipschitz and B Lecka-Czernik. (2004). Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR-gamma2 transcription factor and TGF-beta/BMP signaling pathways. Aging Cell 3:379-389.
    • (2004) Aging Cell , vol.3 , pp. 379-389
    • Moerman, E.J.1    Teng, K.2    Lipschitz, D.A.3    Lecka-Czernik, B.4
  • 65
    • 14244250617 scopus 로고    scopus 로고
    • Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation
    • Ali AA, RS Weinstein, SA Stewart, AM Parfitt, SC Manolagas and RL Jilka. (2005). Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation. Endocrinology 146:1226-1235.
    • (2005) Endocrinology , vol.146 , pp. 1226-1235
    • Ali, A.A.1    Weinstein, R.S.2    Stewart, S.A.3    Parfitt, A.M.4    Manolagas, S.C.5    Jilka, R.L.6
  • 67
    • 12344255130 scopus 로고    scopus 로고
    • by promoting osteoblast/osteocyte apoptosis. J Endocrinol 183:203-216.
    • by promoting osteoblast/osteocyte apoptosis. J Endocrinol 183:203-216.
  • 68
    • 0034331685 scopus 로고    scopus 로고
    • Progressive osseous heteropla- sia
    • Kaplan FS and EM Shore. (2000). Progressive osseous heteropla- sia. J Bone Miner Res 15:2084-2094.
    • (2000) J Bone Miner Res , vol.15 , pp. 2084-2094
    • Kaplan, F.S.1    Shore, E.M.2
  • 71
    • 0034056758 scopus 로고    scopus 로고
    • Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model
    • Muraglia A, R Cancedda and R Quarto. (2000). Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model. J Cell Sci 113 (Pt 7):1161-1166.
    • (2000) J Cell Sci , vol.113 , Issue.PART 7 , pp. 1161-1166
    • Muraglia, A.1    Cancedda, R.2    Quarto, R.3
  • 72
    • 0038657660 scopus 로고    scopus 로고
    • Multilineage differentiation of adult human bone marrow progenitor cells transduced with human papilloma virus type 16 E6/E7 genes
    • Osyczka AM, U Noth, J O'Connor, EJ Caterson, K Yoon, KG Danielson and RS Tuan. (2002). Multilineage differentiation of adult human bone marrow progenitor cells transduced with human papilloma virus type 16 E6/E7 genes. Calcif Tissue Int 71:447-458.
    • (2002) Calcif Tissue Int , vol.71 , pp. 447-458
    • Osyczka, A.M.1    Noth, U.2    O'Connor, J.3    Caterson, E.J.4    Yoon, K.5    Danielson, K.G.6    Tuan, R.S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.