Hyperpolarization Induces Differentiation in Human Cardiomyocyte Progenitor Cells

Stem Cell Reviews and Reports

Volumn 6, Issue 2, 2010, Pages 178-185

  van Vliet, Patrick ^a,b,c   de Boer, Teun P ^a   van der Heyden, Marcel A G ^a   Tamer, Mazen K El ^a   Sluijter, Joost P G ^a,b   Doevendans, Pieter A ^a,b   Goumans, Marie José ^a,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Biophysical signaling; Calcineurin; Cardiomyocyte; Differentiation; Electrophysiology; Membrane potential; Progenitor cell

Indexed keywords

CALCINEURIN; CALCIUM; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL MEMBRANE POTENTIAL; CYTOLOGY; ELECTROPHYSIOLOGY; GENETICS; HEART MUSCLE CELL; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; WESTERN BLOTTING; MEMBRANE POTENTIAL;

BLOTTING, WESTERN; CALCINEURIN; CALCIUM; CELL DIFFERENTIATION; CELLS, CULTURED; ELECTROPHYSIOLOGY; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIALS; MYOCYTES, CARDIAC; POTASSIUM CHANNELS, INWARDLY RECTIFYING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELLS;

EID: 77953915790     PISSN: 15508943     EISSN: 15586804     Source Type: Journal    
DOI: 10.1007/s12015-010-9142-5     Document Type: Article

References (35)

1. Harvey, R. P. (2002). Patterning the vertebrate heart. Nature Reviews Genetics, 3, 544-556.
2. Bergmann, O., Bhardwaj, R. D., Bernard, S., et al. (2009). Evidence for cardiomyocyte renewal in humans. Science, 324, 98-102.
3. Messina, E., De Angelis, L., Frati, G., et al. (2004). Isolation and expansion of adult cardiac stem cells from human and murine heart. Circulation Research, 95, 911-921.
4. Smith, R. R., Barile, L., Cho, H. C., et al. (2007). Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation, 115, 896-908.
5. Goumans, M. J., de Boer, T. P., Smits, A. M., et al. (2007). TGF-beta1 induces efficient differentiation of human cardiomyocyte progenitor cells into functional cardiomyocytes in vitro. Stem Cell Research, 1, 138-149.
6. Bearzi, C., Rota, M., Hosoda, T., et al. (2007). Human cardiac stem cells. Proceedings of the National Academy of Sciences of the United States of America, 104, 14068-14073.
7. Bu, L., Jiang, X., Martin-Puig, S., et al. (2009). Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages. Nature, 460, 113-117.
8. van Vliet, P., Sluijter, J. P., Doevendans, P. A., & Goumans, M. J. (2007). Isolation and expansion of resident cardiac progenitor cells. Expert Review of Cardiovascular Therapy, 5, 33-43.
9. Roccio, M., Goumans, M. J., Sluijter, J. P., & Doevendans, P. A. (2008). Stem cell sources for cardiac regeneration. Panminerva Medica, 50, 19-30.
10. Heng, B. C., Haider, H. K., Sim, E. K., Cao, T., & Ng, S. C. (2004). Strategies for directing the differentiation of stem cells into the cardiomyogenic lineage in vitro. Cardiovascular Research, 62, 34-42.
11. van Vliet, P., Roccio, M., Smits, A. M., et al. (2008). Progenitor cells isolated from the human heart: a potential cell source for regenerative therapy. Netherlands Heart Journal, 16, 163-169.
12. Adams, D. S. (2008). A new tool for tissue engineers: ions as regulators of morphogenesis during development and regeneration. Tissue Engineering Part A, 14, 1461-1468.
13. Sundelacruz, S., Levin, M., & Kaplan, D. L. (2009). Role of membrane potential in the regulation of cell proliferation and differentiation. Stem Cell Reviews and Reports, 5, 231-246.
14. Smits, A. M., van Vliet, P., Metz, C. H., et al. (2009). Human cardiomyocyte progenitor cells differentiate into functional mature cardiomyocytes: an in vitro model for studying human cardiac physiology and pathophysiology. Nature Protocols, 4, 232-243.
15. de Boer, T. P., van Veen, T. A., Houtman, M. J., et al. (2006). Inhibition of cardiomyocyte automaticity by electrotonic application of inward rectifier current from Kir2. 1 expressing cells. Medical & Biological Engineering & Computing, 44, 537-542.
16. Dennler, S., Itoh, S., Vivien, D., ten Dijke, P., Huet, S., & Gauthier, J. M. (1998). Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO Journal, 17, 3091-3100.
17. de Boer, T. P., van Veen, T. A., Jonsson, M. K., et al. (2010). Human cardiomyocyte progenitor cell-derived cardiomyocytes display a maturated electrical phenotype. Journal of Molecular and Cellular Cardiology, 48, 254-260.
18. Konig, S., Beguet, A., Bader, C. R., & Bernheim, L. (2006). The calcineurin pathway links hyperpolarization (Kir2. 1)-induced Ca2+ signals to human myoblast differentiation and fusion. Development, 133, 3107-3114.
19. Lagostena, L., Avitabile, D., De Falco, E., et al. (2005). Electrophysiological properties of mouse bone marrow c-kit+ cells co-cultured onto neonatal cardiac myocytes. Cardiovascular Research, 66, 482-492.
20. Yasuda, T., Bartlett, P. F., & Adams, D. J. (2008). K(ir) and K(v) channels regulate electrical properties and proliferation of adult neural precursor cells. Molecular and Cellular Neuroscience, 37, 284-297.
21. Chilton, L., Ohya, S., Freed, D., et al. (2005). K+ currents regulate the resting membrane potential, proliferation, and contractile responses in ventricular fibroblasts and myofibroblasts. American Journal of Physiology - Heart and Circulatory Physiology, 288, H2931-H2939.
22. Erdogan, A., Schaefer, C. A., Schaefer, M., et al. (2005). Margatoxin inhibits VEGF-induced hyperpolarization, proliferation and nitric oxide production of human endothelial cells. Journal of Vascular Research, 42, 368-376.
23. Bernheim, L., & Bader, C. R. (2002). Human myoblast differentiation: Ca(2+) channels are activated by K(+) channels. News in Physiological Sciences, 17, 22-26.
24. Sundelacruz, S., Levin, M., & Kaplan, D. L. (2008). Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells. PLoS One, 3, e3737.
25. Berridge, M. J., Lipp, P., & Bootman, M. D. (2000). The versatility and universality of calcium signalling. Nature Reviews Molecular Cell Biology, 1, 11-21.
26. Schulz, R. A., & Yutzey, K. E. (2004). Calcineurin signaling and NFAT activation in cardiovascular and skeletal muscle development. Developmental Biology, 266, 1-16.
27. Sato, M., Suzuki, K., Yamazaki, H., & Nakanishi, S. (2005). A pivotal role of calcineurin signaling in development and maturation of postnatal cerebellar granule cells. Proceedings of the National Academy of Sciences of the United States of America, 102, 5874-5879.
28. Chen, Y., & Cao, X. (2009). NFAT directly regulates Nkx2-5 transcription during cardiac cell differentiation. Biology of the Cell, 101, 335-349.
29. Bijlenga, P., Liu, J. H., Espinos, E., et al. (2000). T-type alpha 1H Ca2+ channels are involved in Ca2+ signaling during terminal differentiation (fusion) of human myoblasts. Proceedings of the National Academy of Sciences of the United States of America, 97, 7627-7632.
30. Berridge, M. J., Bootman, M. D., & Roderick, H. L. (2003). Calcium signalling: dynamics, homeostasis and remodelling. Nature Reviews Molecular Cell Biology, 4, 517-529.
31. Ferreira-Martins, J., Rondon-Clavo, C., Tugal, D., et al. (2009). Spontaneous calcium oscillations regulate human cardiac progenitor cell growth. Circulation Research, 105, 764-774.
32. Kawano, S., Shoji, S., Ichinose, S., Yamagata, K., Tagami, M., & Hiraoka, M. (2002). Characterization of Ca(2+) signaling pathways in human mesenchymal stem cells. Cell Calcium, 32, 165-174.
33. Sun, S., Liu, Y., Lipsky, S., & Cho, M. (2007). Physical manipulation of calcium oscillations facilitates osteodifferentiation of human mesenchymal stem cells. FASEB Journal, 21, 1472-1480.
34. Klagsbrun, M., & D'Amore, P. A. (1991). Regulators of angiogenesis. Annual Review of Physiology, 53, 217-239.
35. Scharbrodt, W., Kuhlmann, C. R., Wu, Y., et al. (2004). Basic fibroblast growth factor-induced endothelial proliferation and NO synthesis involves inward rectifier K+ current. Arteriosclerosis, Thrombosis, and Vascular Biology, 24, 1229-1233.