Newt myotubes reenter the cell cycle by phosphorylation of the retinoblastoma protein

Journal of Cell Biology

Volumn 136, Issue 1, 1997, Pages 155-165

  Tanaka, Elly M ^a   Gann, Alexander A F ^a,b   Gates, Phillip B ^a   Brockes, Jeremy P ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b LANCASTER UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BROXURIDINE; CYCLIN DEPENDENT KINASE; DNA; EPIDERMAL GROWTH FACTOR; FIBRONECTIN; GROWTH FACTOR; LAMININ; PLATELET DERIVED GROWTH FACTOR; RETINOBLASTOMA PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VITRONECTIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; CONTACT INHIBITION; CONTROLLED STUDY; MONONUCLEAR CELL; MYOTUBE; NEWT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SERUM;

AMINO ACID SEQUENCE; ANIMALS; BLOOD; CARRIER PROTEINS; CELL COUNT; CELL CYCLE; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASES; DNA REPLICATION; ENZYME INHIBITORS; GROWTH SUBSTANCES; MOLECULAR SEQUENCE DATA; MUSCLE FIBERS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RETINOBLASTOMA PROTEIN; S PHASE; SALAMANDRIDAE;

EID: 0031032050     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.136.1.155     Document Type: Article

References (54)

1. Barres, B.A., M.A. Lazar, and M.C. Raff. 1994. A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development. Development (Camb.). 120:1097-1108.
2. Bernards, R., G.M. Schackleford, M.R. Gerber, J.M. Horowitz, S. H. Friend, M. Schartl, E. Bogenmann, J. Rapaport, T. Mcgee, T. Dryja, et al. 1989. Structure and expression of the murine retinoblastoma gene and characterization of its encoded protein. Proc. Natl. AcatL Sci. USA. 86:6474-6478.
3. Brockes, J.P. 1994. New approaches to amphibian limb regeneration. Trends Genet, 10:169-173.
4. Brown, R., and J.P. Brockes. 1991. Identification and expression of a regeneration-specific homeobox gene in the newt limb blastema. Development (Camb.). 111:489-496.
5. Casimir, CM., P.B. Gates, R.K. Patient, and J.P. Brockes. 1988. Evidence for dedifferentiation and metaplasia in amphibian limb regeneration from inheritance of DNA methytation. Development (Camb.). 104:657-668.
6. Crescenzi, M., S. Soddu, and F. Tato. 1995. Mitotic cycle reactivation in terminally differentiated cells by adenovirus infection. J. Cell. Physiot. 162:26-35.
7. Destree, O.H.J., K.T. Lam, L.J. Peterson-Maduro, K. Eizema, L. Diller, M.A, Gryka, T. Frebourg, E. Shibuya, and S.H. Friend. 1992. Structure and expression of the Xenopus retinoblastoma gene. Dev. Biol. 153:141-149.
8. Eguchi, G., S.-E. Abe, and K. Watanabe. 1974. Differentiation of lens-like structures from newt iris epithelial cells in vitro. Proc. Natl. Acad. Sci. USA. 71:5052-5056.
9. Endo, T., and B. Nadal-Ginard. 1986. Transcriptional and post-transcriptiooal control of c-myc during myogenesis: its mRNA remains inducible in differentiated cells and does not suppress the differentiated phenotype. Mol. Cell. Biol. 6:1412-1421.
10. Endo, T., and B. Nadal-Ginard. 1989. SV40 large T-antigen induces reentry of terminally differentiated myotubes into the cell cycle. In The Cellular and Molecular Biology of Muscle Development. L.H. Kedes and F.E. Stockdale, editors. Alan R. Liss. New York. 95-104.
11. Ferretti, P., and J.P. Brockes. 1988. Culture of newt cells from different tissues and their expression of a regeneration-associated antigen. J. Exp. Zool. 247: 77-91.
12. Frangioni, J.V., and B.C. Neel. 1993. Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins Anal. Biochem. 210(1):179-187.
13. Gu, W., J.W. Schneider, G. Condorelli, S. Kaushal, V. Mahdavi, and B. NadalGinard. 1993. Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell. 72:309-324.
14. ink4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes & Dev. 8:2939-2952.
15. Guo, K., J. Wang, V. Andres, R.C. Smith, and K. Walsh. 1995. MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation. Mol. Cell. Biol. 15(7):3823-3829.
16. Halevy, O., B.G. Novitch, D.O. Spicer, S.X. Skapek, J. Rhee, G.J. Hannon, D. Beach, and A.B. Lassar. 1995. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science. (Wash. DC). 267: 1018-1021.
17. Hamel, P.A., R.M. Gell, R.A. Phillips, and B.L. Gallie. 1992. Transcriptional repression of the E2-containing promoters EIIaI, c-myc, and RB1 by the product of the RB1 gene. Mol. Cell. Biol. 12(8);3431-3438.
18. ink4 is a potential effector of TGFb induced cell cycle arrest. Nature (Land.). 371:257-260.
19. Barlow, E., and D. Lane. 1988. Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. 726 pp.
20. Hay, E.D. 1959. Electron microscopic observations of muscle dedifferentiation in regenerating Amblystoma limbs. Dev. Biol. 1:555-585.
21. Hu, J.-S., and E.N. Olson. 1990. Functional receptors for transforming growth factor β are retained in biochemically differentiated C2 myocytes in growth factor deficient medium containing EGTA but down-regulated during terminal differentiation. J. Biol. Chem. 265:7914-7919.
22. Hu, Q., C. Bautista, G.M. Edwards, D. Defeo-Jones, R.E. Jones, and E. Harlow. 1991. Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides. Mol. Cell. Biol. 11:5792-5799.
23. Hunter, T., and J. Pines. 1994. Cyclins and cancer II: cyclin D and CDK inhibitors come of age. Cell. 79:573-582.
24. Iujvidin, S., O. Fuchs, U. Nudel, and D. Yaffe. 1990. SV40 immortalizes myogenic cells: DNA synthesis and mitosis in differentiating myotubes. Differentiation. 43:192-203.
25. 2/M and cease muscle gene expression. J. Cell. Biol. 121:785-793.
26. Kintner, C.R., and J.P. Brockes. 1984. Monoclonal antibodies identify blastemal cells derived from de-differentiating muscle in newt limb regeneration. Nature (Lond.). 308:67-69.
27. Koh, J., G.H. Enders, B.D. Dynlacht, and E. Harlow. 1995. Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition. Nature (Lond.). 375:506-510.
28. Lassar, A.B., S.X. Skapek, and B. Novitch. 1994. Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal. Curr. Biol. 6:788-794.
29. LaThangue, N.B. 1994. DRTF1/E2F: an expanding family of helerodimeric transcription factors implicated in cell cycle control. Trends Biochem. Sci. 19: 108-114.
30. Lo, D.C., F. Alien, and J.P. Brockes. 1993. Reversal of muscle differentiation during urodele limb regeneration. Proc. Natl. Acad. Sci. USA. 90:7230-7234.
31. Ludlow, J.W., J.A. DeCaprio, C.-M. Huang, W.-H. Lee, E. Paucha, and D.M. Livingston. 1989. SV40 Large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family. Cell. 56:57-65.
32. Lukas, J., H. Müller, J. Bartkova, D. Spitkovsky, A.A. Kjerulff, P. Jansen-Dürr, M. Strauss, and J. Bartek. 1994. DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relievo the cell's requirement for cyclin D1 function in G1. J. Cell Biol. 125:625-638.
33. Lukas, J., D. Parry, L. Aagaard, D.J. Mann, J. Bartkova, M. Strauss, G. Peters, and J. Bartek. 1995. Retinoblastoma protein-dependent cell-cycle inhibition by the tumour suppressor p16. Nature (Land.). 375:503-506.
34. INK4 requires functional retinoblastoma protein. Proc. Natl. Acad. Sci. USA. 92:6289-6293.
35. Namenwirth, M. 1974. The inheritance of cell differentiation during limb regeneration in the Axolotl. Dev. Biol. 41:42-56.
36. Nevins, J.R. 1992. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science (Wash. DC). 258:424-429.
37. Okada, T.S. 1991. Transdifferentiation. Oxford University Press, UK. 238 pp.
38. Oison, E.N. 1992. Interplay between proliferation and differentiation within the myogenic lineage. Dev. Biol. 154:261-272.
39. Olwin, B.B., and S.D. Hauschka. 1988. Cell surface fibroblast growth factor and epidermal growth factor receptors are permanently lost during skeletal mus-cle terminal differentiation in culture. J. Cell Biol. 107:761-769.
40. cip1 in muscle and other terminally differentiating cells. Science (Wash. DC). 267:1024-1027.
41. INK4/MTS1 tumor suppressor gene product. EMBO (Eur. Mol. Biol. Organ.) J. 14(3):503-511.
42. Riley, D.J., E.Y.-H.P. Lee, and W.-H. Lee. 1995. The retinoblastoma protein: more than a tumor suppressor. Anna. Rev. Cell Biol. 10:1-29.
43. Rothblat, G.H., L.Y. Arbogast, L. Ouellette, and B.V. Howard. 1976. Preparation of delipidized serum protein for use in cell culture systems. In Vitro (Rockville). 12:554-557.
44. Schilthuis, J.G., A.A.F. Gann, and J.P. Brockes. 1993. Chimaeric retinoic acid/ thyroid hormone receptors implicate RARα1 as mediating growth inhibition by retinoic acid. EMBO (Eur. Mol. Biol. Organ.) J. 12:3459-3466.
45. -/- muscle cells. Science (Wash. DC). 264:1467-1471.
46. Serrano, M., G.J. Hannon, and D. Beach. 1993. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature (Lond.). 366:704-707.
47. Sheaff, R.J., and J.M. Roberts. 1995. Lessons in p16 from phylum Falconium. Curr. Biol. 5:28-31.
48. Sherr, C.J. 1994. G1 phase progression: cycling on cue. Cell. 79:551-555.
49. Sherr, C.J., and J.M. Roberts. 1995. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes & Dev. 9:1149-1163.
50. Steen, T.P. 1968. Stability of chondrocyte differentiation and contribution of muscle to cartilage during limb regeneration in the axolotl (Siredon mexicanum). J. Exp. Zool. 167:49-77.
51. Wallace, H. 1981. Vertebrate Limb Regeneration. John Wiley & Sons, Chichester, UK. 276 pp.
52. Wallace, H., and M. Maden. 1976. The cell cycle during amphibian limb regeneration. J. Cell Sci. 20:539-547.
53. Weinberg, R.A. 1995. The retinoblastoma protein and cell cycle control. Cell. 81:323-330.
54. Xiong, Y., H. Zhang, and D. Beach. 1993. Subunit rearrangement of the cyclindependent kinases is associated with cellular transformation. Genes & Dev. 7:1572-1583.