Stimulatory effects of basic fibroblast growth factor and bone morphogenetic protein-2 on osteogenic differentiation of rat bone marrow- derived mesenchymal stem cells

Journal of Bone and Mineral Research

Volumn 12, Issue 10, 1997, Pages 1606-1614

  Hanada, Keigo ^a,b   Dennis, James E ^a   Caplan, Arnold I ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KAKEN PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BONE MORPHOGENETIC PROTEIN; CALCIUM PHOSPHATE; DEXAMETHASONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; BONE MINERALIZATION; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CONTROLLED STUDY; HISTOPATHOLOGY; MALE; NONHUMAN; PROTEIN ANALYSIS; RAT; SCORING SYSTEM;

ANIMALS; BONE MORPHOGENETIC PROTEINS; CALCIUM; CALCIUM PHOSPHATES; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; CERAMICS; DRUG SYNERGISM; FIBROBLAST GROWTH FACTOR 2; HEMATOPOIETIC STEM CELLS; MALE; MESODERM; MITOGENS; OSTEOGENESIS; RATS; RATS, INBRED F344; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030804095     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1997.12.10.1606     Document Type: Article

References (34)

1. Owen M 1988 Marrow stromal stem cells. J Cell Sci (Suppl) 10:63-76.
2. Caplan AI 1991 Mesenchymal stem cells. J Orthop Res 9:641-650.
3. Caplan AI 1993 The mesengenic process. Clin Plastic Surg 21:429-435.
4. Ashton BA, Allen TD, Howlett CR, Eaglesom CC, Hattori A, Owen M 1980 Formation of bone and cartilage by marrow stromal cells in diffusion chambers in vivo. Clin Orthop 151:294-307.
5. Friedenstein AJ, Chailakhyan RK, Gerasimov U 1987 Bone marrow osteogenic cells: In vitro cultivation and transplantation in diffusion chambers. Cell Tissue Kinet 20:263-272.
6. Goshima J, Goldberg VM, Caplan AI 1991 The osteogenic potential of culture-expanded rat marrow mesenchymal cells assayed in vivo in calcium phosphate ceramic blocks. Clin Orthop 262:298-311.
7. Dennis JE, Haynesworth SE, Young RG, Caplan AI 1992 Osteogenesis in marrow-derived mesenchymal cell porous ceramic composites transplanted subcutaneously: Effect of fibronectin and laminin on cell retention and rate of osteogenic expression. Cell Transplant 1:23-32.
8. Haynesworth SE, Goshima J, Goldberg VM, Caplan AI 1992 Characterization of cells with osteogenic potential from human marrow. Bone 13:81-88.
9. Maniatopoulos C, Sodek J, Melcher AH 1988 Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats. Cell Tissue Res 254:317-330.
10. Herbertson A, Aubin JE 1995 Dexamethasone alters the subpopulation make-up of rat bone marrow stromal cell cultures. J Bone Miner Res 10:285-294.
11. Globus RK, Patterson-Buckendahl P, Gospodarowicz D 1988 Regulation of bovine bone cell proliferation by fibroblast growth factor and transforming growth factor β. Endocrinology 123:98-105.
12. Rodan SB, Wesolowski G, Thomas KA, Yoon K, Rodan GA 1989 Effects of acidic and basic fibroblast growth factors on osteoblastic cells. Conn Tissue Res 20:283-288.
13. Cannalis E, Centrella M, MacCarthy TL 1988 Effects of basic fibroblast growth factor on bone formation in vitro. J Clin Invest 81:1572-1577.
14. Katagiri T, Yamaguchi A, Ikeda T, Yoshiki S, Wozney JM, Rosen V, Wang EA, Tanaka H, Omura S, Suda T 1990 The nonosteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2. Biochem Biophys Res Commun 172:295-299.
15. Yamaguchi A, Katagiri T, Ikeda T, Wozney JM, Rosen V, Wang EA, Kahn AJ, Suda T, Yoshiki S 1991 Recombinant human bone morphogenetic protein-2 stimulates osteoblast maturation and inhibits myogenic differentiation in vitro. J Cell Biol 113:681-687.
16. Kawaguchi H, Kurokawa T, Hanada K, Hiyama Y, Tamura M, Ogata E, Matsumoto T 1994 Stimulation of fracture repair by recombinant human basic fibroblast growth factor in normal and streptozotocin-diabetic rats. Endocrinology 135:774-781.
17. Nakamura T, Hanada K, Tamura M, Shibanushi T, Nigi H, Tagawa M, Fukumoto S, Matsumoto T 1995 Stimulation of endosteal bone formation by systemic injection of recombinant basic fibroblast growth factor in rats. Endocrinology 136:1276-1284.
18. Pitaru S, Kotev-Emeth S, Noff D, Kaffuler S, Savion N 1993 Effect of basic fibroblast growth factor on the growth and differentiation of adult stromal bone marrow cells: Enhanced development of mineralized bone-like tissue in culture. J Bone Miner Res 8:919-929.
19. Savion N, Pri-Chen S, Pitaru S 1996 bFGF enhances the growth and the expression of osteogenic phenotype of dexamethasone treated human bone marrow derived bone-like cells in culture. J Bone Miner Res 11:S347 (abstract).
20. Majors AE, Muschler GF 1996 Basic FGF enhances proliferation and reversively inhibits differentiation of osteoblastic progenitors. Trans Orth Res Soc 21:113 (abstract).
21. Rickard DJ, Sullivan TA, Shenker BJ, Leboy PS, Kazhdan I 1994 Induction of rapid osteoblast differentiation in rat bone marrow stromal cell cultures by dexamethasone and BMP-2. Dev Biol 161:218-228.
22. Mundy GR, Boyce B. Hughes D. Wright K, Bonewald L, Dallas S, Harris S, Ghosh-Choudhury N, Chen D, Dunstan C, Izbicka E, Yoneda T 1995 The effects of cytokines and growth factors on osteoblastic cells. Bone 17:71S-75S.
23. Wang EA, Israel DI, Kelly S, Luxenberg DP 1993 Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells. Growth Factors 9:57-51.
24. Lennon DP, Haynesworth SE, Bruder SP, Jaiswal N, Caplan AI 1996 Human and animal mesenchymal progenitor cells from bone marrow: Identification of serum for optimal selection and proliferation. In Vitro Cell Dev Biol (in press).
25. Lennon DP, Haynesworth SE, Young RG, Dennis JE, Caplan AI 1995 A chemically defined medium supports in vitro proliferation and maintains the osteochondral potential of rat marrow-derived mesenchymal stem cells. Exp Cell Res 219:211-222.
26. Cassiede P, Dennis JE, Ma F, Caplan AI 1996 Osteochodrogenic potential of marrow mesenchymal progenitor cells exposed to TGF-β1 or PDGF-BB as assayed in vivo and in vitro. J Bone Miner Res 11:1264-1273.
27. Gillery P, Bonnet A, Borel J-P 1993 A fluorometric deoxyribonucleic acid assay for tridimentional lattice cultures of fibroblasts. Anal Biochem 210:374-377.
28. Araki N, Robinson FD, Nishimoto SK 1993 Rapid and sensitive method for quantitation of bone gla protein mRNA using competitive polymerase chain reaction. J Bone Miner Res 8:313-322.
29. Iwasaki M, Nakahara H, Nakase T, Kimura T, Takaoka K, Caplan AI, Ono K 1994 Bone morphogenetic protein 2 stimulates osteogenesis but does not affect chondrogenesis in osteochondrogenic differentiation of periosteum-derived cells. J Bone Miner Res 9:1195-1204.
30. Boden SD, McCuaig K, Hair G, Rachine M, Titus L, Wozney JM, Hanes MS 1996 Differential effects and glucocorticoid potentiation of bone morphogenetic protein action during rat osteoblast differentiation in vitro. Endocrinology 137:3401-3407.
31. Boden SD, Hair G, Rachine M, McCuaig K, Wozney JM, Hanes MS 1996 Glucocorticoid-induced differentiation of fetal rat calvarial osteoblasts is mediated by BMP-6. J Bone Miner Res 11:S117.
32. Thies RS, Bauduy M, Ashton BA, Kurtzberg L, Wozney JM, Rosen V 1992 Recombinant human bone morphogenetic protein-2 induces osteoblastic differentiation in W-20-17 stromal cells. Endocrinology 130:1318-1324.
33. Hughes FJ, Collyer J, Stanfield M, Goodman SA 1995 The effects of bone morphogenetic protein-2, -4, and -6 on differentiation of rat osteoblast cells in vitro. Endocrinology 136:2671-2677.
34. Linkhart TA, Mohan S, Baylink DJ 1996 Growth factors for bone growth and repair: IGF, TGFβ and BMP. Bone 19:1S-12S.