Local irradiation not only induces homing of human mesenchymal stem cells at exposed sites but promotes their widespread engraftment to multiple organs: A study of their quantitative distribution after irradiation damage

Stem Cells

Volumn 24, Issue 4, 2006, Pages 1020-1029

  François, Sabine ^a   Bensidhoum, Morad ^b   Mouiseddine, Moubarak ^a   Mazurier, Christelle ^b   Allenet, Bénédicte ^a   Semont, Alexandra ^a   Frick, Johanna ^a   Saché, Amandine ^a   Bouchet, Sandrine ^b   Thierry, Dominique ^a   Gourmelon, Patrick ^a   Gorin, Norbert Claude ^b,c   Chapel, Alain ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c HÔPITAL SAINT ANTOINE   (France)

Author keywords

Homing; Injured tissues; Irradiation; Mesenchymal stem cell; Transplantation

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL MIGRATION; CELLULAR DISTRIBUTION; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; HISTOLOGY; HUMAN; HUMAN CELL; INTESTINE; LIVER; LUNG; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; MUSCLE; NONHUMAN; QUADRICEPS FEMORIS MUSCLE; QUANTITATIVE ANALYSIS; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; SKIN; SPLEEN; TISSUE DISTRIBUTION; WHOLE BODY RADIATION; ANIMAL; ANTIBODY SPECIFICITY; CELL MOTION; CYTOLOGY; GENE EXPRESSION; GENETICS; GRAFT SURVIVAL; MESENCHYMAL STEM CELL; METABOLISM; MOUSE MUTANT; NONOBESE DIABETIC MOUSE; PATHOLOGY; PHYSIOLOGY; XENOGRAFT;

ANIMALIA;

BETA 2 MICROGLOBULIN; GLOBIN;

ANIMALS; BETA 2-MICROGLOBULIN; CELL MOVEMENT; GENE EXPRESSION; GLOBINS; GRAFT SURVIVAL; HUMANS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED NOD; MICE, SCID; ORGAN SPECIFICITY; RADIATION INJURIES, EXPERIMENTAL; TRANSPLANTATION, HETEROLOGOUS; WHOLE-BODY IRRADIATION;

EID: 33745503500     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2005-0260     Document Type: Article

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