Hydrophobic modification of low molecular weight polyethylenimine for improved gene transfection

Biomaterials

Volumn 34, Issue 32, 2013, Pages 7971-7979

  Teo, Pei Yun ^a,c   Yang, Chuan ^a   Hedrick, James L ^b   Engler, Amanda C ^b   Coady, Daniel J ^b   Ghaem Maghami, Sadaf ^c   George, Andrew J T ^c   Yang, Yi Yan ^a  

^a INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

^b IBM ALMADEN RESEARCH CENTER   (United States)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Cyclic carbonate; Gene transfection; Hydrophobic modification; Low molecular weight polyethylenimine; Nucleophilic addition; Structure function relationship

Indexed keywords

CYCLIC CARBONATES; GENE TRANSFECTION; HYDROPHOBIC MODIFICATION; NUCLEOPHILIC ADDITIONS; POLYETHYLENIMINES; STRUCTURE-FUNCTION RELATIONSHIP;

ADDITION REACTIONS; CELL CULTURE; CYTOTOXICITY; EFFICIENCY; FUNCTIONAL GROUPS; GENES; HYDROGEN BONDS; HYDROPHOBICITY; METABOLISM; MOLECULAR WEIGHT; PARTICLE SIZE; POLYMERS; UREA; ZETA POTENTIAL;

MOLECULAR BIOLOGY;

LOW MOLECULAR WEIGHT POLYETHYLENIMINE; POLYETHYLENEIMINE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CYTOTOXICITY; DNA BINDING; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO GENE TRANSFER; LIVER CELL CARCINOMA; OVARY CANCER; PARTICLE SIZE; PRIORITY JOURNAL; ZETA POTENTIAL;

EID: 84881026547     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.07.005     Document Type: Article

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