Lipid substitution on low molecular weight (0.6-2.0 kDa) polyethylenimine leads to a higher zeta potential of plasmid DNA and enhances transgene expression

Acta Biomaterialia

Volumn 7, Issue 5, 2011, Pages 2209-2217

  Remant Bahadur, K C ^a   Landry, Breanne ^a   Aliabadi, Hamidreza Montazeri ^a   Lavasanifar, Afsaneh ^a   Uludaǧ, Hasan ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Cationic polymers; Hydrophobic modification; Non viral gene delivery; Polyethylenimine; Transfection

Indexed keywords

DNA; EFFICIENCY; GENE EXPRESSION; GENE TRANSFER; MAMMALS; MOLECULAR WEIGHT; PALMITIC ACID; ZETA POTENTIAL;

CATIONIC POLYMERS; HYDROPHOBIC MODIFICATION; IN-VITRO; LOW MOLECULAR WEIGHT; LOW-MOLECULAR-WEIGHT POLYMERS; NON-VIRAL GENE DELIVERY; PLASMID DNA; POLY(ETHYLENIMINE); POLYMER MOLECULAR WEIGHT; TRANSFECTION;

BIOMOLECULES;

CHLOROQUINE; LIPID; PALMITIC ACID; PLASMID DNA; POLYETHYLENEIMINE;

ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO GENE TRANSFER; IN VITRO STUDY; MOLECULAR WEIGHT; PRIORITY JOURNAL; SUBSTITUTION REACTION; TOXICITY; TRANSGENE; ZETA POTENTIAL;

MAMMALIA;

EID: 79953854385     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2011.01.027     Document Type: Article

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