Lipoic acid modified low molecular weight polyethylenimine mediates nontoxic and highly potent in vitro gene transfection

Molecular Pharmaceutics

Volumn 8, Issue 6, 2011, Pages 2434-2443

  Zheng, Meng ^a   Zhong, Yinan ^a   Meng, Fenghua ^a   Peng, Rui ^b   Zhong, Zhiyuan ^a  

^a Department of Polymer Science and Engineering   (China)

^b SOOCHOW UNIVERSITY   (China)

Author keywords

gene delivery; hydrophobic modification; plasmid DNA; polyethylenimine; polyplexes; reduction sensitive

Indexed keywords

POLYETHYLENEIMINE; THIOCTIC ACID;

ARTICLE; CELL STRAIN; CHEMICAL MODIFICATION; COMPLEX FORMATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DNA VECTOR; DRUG CONJUGATION; DRUG DNA BINDING; DRUG POTENCY; ELECTRIC POTENTIAL; GEL ELECTROPHORESIS; GENE DELIVERY SYSTEM; GENE THERAPY; HELA CELL; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; LIGHT SCATTERING; LIPOYLATION; MOLECULAR SIZE; MOLECULAR WEIGHT; PRIORITY JOURNAL; SUBSTITUTION REACTION;

DNA; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE TRANSFER TECHNIQUES; HELA CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; PARTICLE SIZE; POLYETHYLENEIMINE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THIOCTIC ACID; TRANSFECTION;

EID: 82955173004     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp2003797     Document Type: Article

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