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Volumn 24, Issue 4, 2013, Pages 803-809

Predicting phenotypic variation from genotypes, phenotypes and a combination of the two

Author keywords

[No Author keywords available]

Indexed keywords

ACCURATE PREDICTION; FUNDAMENTAL LIMITATIONS; GENETIC PREDICTION; MOLECULAR MEASUREMENTS; MOLECULAR PHENOTYPES; PHENOTYPIC TRAITS; PHENOTYPIC VARIATIONS; TREATMENT OUTCOMES;

EID: 84880956874     PISSN: 09581669     EISSN: 18790429     Source Type: Journal    
DOI: 10.1016/j.copbio.2013.03.004     Document Type: Review
Times cited : (19)

References (63)
  • 1
    • 0000508160 scopus 로고
    • Cause and effect in biology
    • Mayr E. Cause and effect in biology. Science 1961, 134:1501-1506.
    • (1961) Science , vol.134 , pp. 1501-1506
    • Mayr, E.1
  • 2
    • 0037165942 scopus 로고    scopus 로고
    • Combinatorial synthesis of genetic networks
    • Guet C.C., Elowitz M.B., Hsing W., Leibler S. Combinatorial synthesis of genetic networks. Science 2002, 296:1466-1470.
    • (2002) Science , vol.296 , pp. 1466-1470
    • Guet, C.C.1    Elowitz, M.B.2    Hsing, W.3    Leibler, S.4
  • 6
    • 0030797355 scopus 로고    scopus 로고
    • Robustness in simple biochemical networks
    • Barkai N., Leibler S. Robustness in simple biochemical networks. Nature 1997, 387:913-917.
    • (1997) Nature , vol.387 , pp. 913-917
    • Barkai, N.1    Leibler, S.2
  • 7
    • 77949386270 scopus 로고    scopus 로고
    • Genes confer similar robustness to environmental, stochastic, and genetic perturbations in yeast
    • Lehner B. Genes confer similar robustness to environmental, stochastic, and genetic perturbations in yeast. PLoS One 2010, 5:e9035.
    • (2010) PLoS One , vol.5
    • Lehner, B.1
  • 8
    • 84867272347 scopus 로고    scopus 로고
    • Boolean modeling in systems biology: an overview of methodology and applications
    • Wang R.S., Saadatpour A., Albert R. Boolean modeling in systems biology: an overview of methodology and applications. Phys Biol 2012, 9:055001.
    • (2012) Phys Biol , vol.9 , pp. 055001
    • Wang, R.S.1    Saadatpour, A.2    Albert, R.3
  • 9
    • 84867349994 scopus 로고    scopus 로고
    • Predictive computation of genomic logic processing functions in embryonic development
    • Peter I.S., Faure E., Davidson E.H. Predictive computation of genomic logic processing functions in embryonic development. Proc Natl Acad Sci U S A 2012, 109:16434-16442.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 16434-16442
    • Peter, I.S.1    Faure, E.2    Davidson, E.H.3
  • 12
    • 51249106485 scopus 로고    scopus 로고
    • The loci of evolution: how predictable is genetic evolution?
    • Stern D.L., Orgogozo V. The loci of evolution: how predictable is genetic evolution?. Evolution 2008, 62:2155-2177.
    • (2008) Evolution , vol.62 , pp. 2155-2177
    • Stern, D.L.1    Orgogozo, V.2
  • 13
    • 0031824633 scopus 로고    scopus 로고
    • Prediction of mutant expression patterns using gene circuits
    • Sharp D.H., Reinitz J. Prediction of mutant expression patterns using gene circuits. Biosystems 1998, 47:79-90.
    • (1998) Biosystems , vol.47 , pp. 79-90
    • Sharp, D.H.1    Reinitz, J.2
  • 16
    • 82255186724 scopus 로고    scopus 로고
    • Predicting phenotypic variation in yeast from individual genome sequences
    • Jelier R., Semple J.I., Garcia-Verdugo R., Lehner B. Predicting phenotypic variation in yeast from individual genome sequences. Nat Genet 2011, 43:1270-1274.
    • (2011) Nat Genet , vol.43 , pp. 1270-1274
    • Jelier, R.1    Semple, J.I.2    Garcia-Verdugo, R.3    Lehner, B.4
  • 17
    • 62649126517 scopus 로고    scopus 로고
    • Comprehensive polymorphism survey elucidates population structure of Saccharomyces cerevisiae
    • Schacherer J., Shapiro J.A., Ruderfer D.M., Kruglyak L. Comprehensive polymorphism survey elucidates population structure of Saccharomyces cerevisiae. Nature 2009, 458:342-345.
    • (2009) Nature , vol.458 , pp. 342-345
    • Schacherer, J.1    Shapiro, J.A.2    Ruderfer, D.M.3    Kruglyak, L.4
  • 26
    • 84867098571 scopus 로고    scopus 로고
    • Beyond genotype to phenotype: why the phenotype of an individual cannot always be predicted from their genome sequence and the environment that they experience
    • Burga A., Lehner B. Beyond genotype to phenotype: why the phenotype of an individual cannot always be predicted from their genome sequence and the environment that they experience. FEBS J 2012, 279:3765-3775.
    • (2012) FEBS J , vol.279 , pp. 3765-3775
    • Burga, A.1    Lehner, B.2
  • 27
    • 33745905942 scopus 로고    scopus 로고
    • The incidentalome: a threat to genomic medicine
    • Kohane I.S., Masys D.R., Altman R.B. The incidentalome: a threat to genomic medicine. JAMA 2006, 296:212-215.
    • (2006) JAMA , vol.296 , pp. 212-215
    • Kohane, I.S.1    Masys, D.R.2    Altman, R.B.3
  • 29
    • 68249108329 scopus 로고    scopus 로고
    • Prediction and interaction in complex disease genetics: experience in type 1 diabetes
    • Clayton D.G. Prediction and interaction in complex disease genetics: experience in type 1 diabetes. PLoS Genet 2009, 5:e1000540.
    • (2009) PLoS Genet , vol.5
    • Clayton, D.G.1
  • 30
    • 79961180449 scopus 로고    scopus 로고
    • Epidemiology, epigenetics and the 'Gloomy Prospect': embracing randomness in population health research and practice
    • Smith G.D. Epidemiology, epigenetics and the 'Gloomy Prospect': embracing randomness in population health research and practice. Int J Epidemiol 2011, 40:537-562.
    • (2011) Int J Epidemiol , vol.40 , pp. 537-562
    • Smith, G.D.1
  • 31
    • 79957665988 scopus 로고    scopus 로고
    • Microarrays, deep sequencing and the true measure of the transcriptome
    • Malone J.H., Oliver B. Microarrays, deep sequencing and the true measure of the transcriptome. BMC Biol 2011, 9:34.
    • (2011) BMC Biol , vol.9 , pp. 34
    • Malone, J.H.1    Oliver, B.2
  • 33
    • 5644251671 scopus 로고    scopus 로고
    • Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death
    • Onken M.D., Worley L.A., Ehlers J.P., Harbour J.W. Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death. Cancer Res 2004, 64:7205-7209.
    • (2004) Cancer Res , vol.64 , pp. 7205-7209
    • Onken, M.D.1    Worley, L.A.2    Ehlers, J.P.3    Harbour, J.W.4
  • 39
    • 34548667973 scopus 로고    scopus 로고
    • Telomere length, stem cells and aging
    • Blasco M.A. Telomere length, stem cells and aging. Nat Chem Biol 2007, 3:640-649.
    • (2007) Nat Chem Biol , vol.3 , pp. 640-649
    • Blasco, M.A.1
  • 45
    • 83055180178 scopus 로고    scopus 로고
    • Predicting mutation outcome from early stochastic variation in genetic interaction partners
    • Burga A., Casanueva M.O., Lehner B. Predicting mutation outcome from early stochastic variation in genetic interaction partners. Nature 2011, 480:250-253.
    • (2011) Nature , vol.480 , pp. 250-253
    • Burga, A.1    Casanueva, M.O.2    Lehner, B.3
  • 47
    • 0027331339 scopus 로고
    • Growth in utero and serum cholesterol concentrations in adult life
    • Barker D.J., Martyn C.N., Osmond C., Hales C.N., Fall C.H. Growth in utero and serum cholesterol concentrations in adult life. BMJ 1993, 307:1524-1527.
    • (1993) BMJ , vol.307 , pp. 1524-1527
    • Barker, D.J.1    Martyn, C.N.2    Osmond, C.3    Hales, C.N.4    Fall, C.H.5
  • 48
    • 0029050563 scopus 로고
    • Fetal origins of coronary heart disease
    • Barker D.J. Fetal origins of coronary heart disease. BMJ 1995, 311:171-174.
    • (1995) BMJ , vol.311 , pp. 171-174
    • Barker, D.J.1
  • 49
    • 0026772772 scopus 로고
    • Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis
    • Hales C.N., Barker D.J. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia 1992, 35:595-601.
    • (1992) Diabetologia , vol.35 , pp. 595-601
    • Hales, C.N.1    Barker, D.J.2
  • 50
    • 0019828956 scopus 로고
    • Is the similarity of monozygotic twins due to genetic factors alone?
    • Gartner K., Baunack E. Is the similarity of monozygotic twins due to genetic factors alone?. Nature 1981, 292:646-647.
    • (1981) Nature , vol.292 , pp. 646-647
    • Gartner, K.1    Baunack, E.2
  • 51
    • 26844516176 scopus 로고    scopus 로고
    • Variability in gene expression and tumor formation within genetically homogeneous animal populations in bioassays
    • Wolff G.L. Variability in gene expression and tumor formation within genetically homogeneous animal populations in bioassays. Fundam Appl Toxicol 1996, 29:176-184.
    • (1996) Fundam Appl Toxicol , vol.29 , pp. 176-184
    • Wolff, G.L.1
  • 52
    • 0027374296 scopus 로고
    • Adult phenotype in the mouse can be affected by epigenetic events in the early embryo
    • Reik W., Romer I., Barton S.C., Surani M.A., Howlett S.K., Klose J. Adult phenotype in the mouse can be affected by epigenetic events in the early embryo. Development 1993, 119:933-942.
    • (1993) Development , vol.119 , pp. 933-942
    • Reik, W.1    Romer, I.2    Barton, S.C.3    Surani, M.A.4    Howlett, S.K.5    Klose, J.6
  • 55
    • 1942453302 scopus 로고    scopus 로고
    • Predicting gene expression from sequence
    • Beer M.A., Tavazoie S. Predicting gene expression from sequence. Cell 2004, 117:185-198.
    • (2004) Cell , vol.117 , pp. 185-198
    • Beer, M.A.1    Tavazoie, S.2
  • 56
    • 0033707946 scopus 로고    scopus 로고
    • Using Bayesian networks to analyze expression data
    • Friedman N., Linial M., Nachman I., Pe'er D. Using Bayesian networks to analyze expression data. J Comput Biol 2000, 7:601-620.
    • (2000) J Comput Biol , vol.7 , pp. 601-620
    • Friedman, N.1    Linial, M.2    Nachman, I.3    Pe'er, D.4
  • 57
    • 36949030484 scopus 로고    scopus 로고
    • Predicting gene expression from sequence: a reexamination
    • Yuan Y., Guo L., Shen L., Liu J.S. Predicting gene expression from sequence: a reexamination. PLoS Comput Biol 2007, 3:e243.
    • (2007) PLoS Comput Biol , vol.3
    • Yuan, Y.1    Guo, L.2    Shen, L.3    Liu, J.S.4
  • 58
    • 0022429106 scopus 로고
    • The OR control system of bacteriophage lambda. A physical-chemical model for gene regulation
    • Shea M.A., Ackers G.K. The OR control system of bacteriophage lambda. A physical-chemical model for gene regulation. J Mol Biol 1985, 181:211-230.
    • (1985) J Mol Biol , vol.181 , pp. 211-230
    • Shea, M.A.1    Ackers, G.K.2
  • 59
    • 33749137281 scopus 로고    scopus 로고
    • Quantitative and predictive model of transcriptional control of the Drosophila melanogaster even skipped gene
    • Janssens H., Hou S., Jaeger J., Kim A.R., Myasnikova E., Sharp D., Reinitz J. Quantitative and predictive model of transcriptional control of the Drosophila melanogaster even skipped gene. Nat Genet 2006, 38:1159-1165.
    • (2006) Nat Genet , vol.38 , pp. 1159-1165
    • Janssens, H.1    Hou, S.2    Jaeger, J.3    Kim, A.R.4    Myasnikova, E.5    Sharp, D.6    Reinitz, J.7
  • 60
    • 38749127589 scopus 로고    scopus 로고
    • Predicting expression patterns from regulatory sequence in Drosophila segmentation
    • Segal E., Raveh-Sadka T., Schroeder M., Unnerstall U., Gaul U. Predicting expression patterns from regulatory sequence in Drosophila segmentation. Nature 2008, 451:535-540.
    • (2008) Nature , vol.451 , pp. 535-540
    • Segal, E.1    Raveh-Sadka, T.2    Schroeder, M.3    Unnerstall, U.4    Gaul, U.5
  • 61
    • 58149354385 scopus 로고    scopus 로고
    • Analysis of combinatorial cis-regulation in synthetic and genomic promoters
    • Gertz J., Siggia E.D., Cohen B.A. Analysis of combinatorial cis-regulation in synthetic and genomic promoters. Nature 2009, 457:215-218.
    • (2009) Nature , vol.457 , pp. 215-218
    • Gertz, J.1    Siggia, E.D.2    Cohen, B.A.3
  • 62
    • 79957983166 scopus 로고    scopus 로고
    • Integrated genome-scale prediction of detrimental mutations in transcription networks
    • Francesconi M., Jelier R., Lehner B. Integrated genome-scale prediction of detrimental mutations in transcription networks. PLoS Genet 2011, 7:e1002077.
    • (2011) PLoS Genet , vol.7
    • Francesconi, M.1    Jelier, R.2    Lehner, B.3
  • 63
    • 78649317608 scopus 로고    scopus 로고
    • Predicting genetic predisposition in humans: the promise of whole-genome markers
    • de los Campos G., Gianola D., Allison D.B. Predicting genetic predisposition in humans: the promise of whole-genome markers. Nat Rev Genet 2010, 11:880-886.
    • (2010) Nat Rev Genet , vol.11 , pp. 880-886
    • de los Campos, G.1    Gianola, D.2    Allison, D.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.