메뉴 건너뛰기




Volumn 23, Issue 8, 2013, Pages 403-414

Pharmacogenetics in American Indian populations: Analysis of CYP2D6, CYP3A4, CYP3A5, and CYP2C9 in the confederated salish and kootenai tribes

Author keywords

Alaska Native; American Indian; CYP2C9; CYP2D6; CYP3A4; CYP3A5; cytochrome P450; indigenous populations; pharmacogenetics; pharmacogenomics

Indexed keywords

CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5;

EID: 84880916736     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e3283629ce9     Document Type: Article
Times cited : (53)

References (86)
  • 2
    • 84863726266 scopus 로고    scopus 로고
    • American Indian/Alaska Native cancer policy: Systemic approaches to reducing cancer disparities
    • Warne D, Kaur J, Perdue D. American Indian/Alaska Native cancer policy: systemic approaches to reducing cancer disparities. J Cancer Educ 2012; 27 (Suppl 1):S18-S23
    • (2012) J Cancer Educ , vol.27 , Issue.SUPPL. 1
    • Warne, D.1    Kaur, J.2    Perdue, D.3
  • 3
    • 17844397805 scopus 로고    scopus 로고
    • Indian Health Disparities. Accessed 5 October 2012
    • Indian Health Service fact sheets. Indian health disparities. Available at: http://www.ihs.gov/FactSheets/documents/Disparities.pdf [Accessed 5 October 2012]
    • Indian Health Service Fact Sheets
  • 4
    • 79951782374 scopus 로고    scopus 로고
    • Ethical issues in developing pharmacogenetic research partnerships with American indigenous communities
    • Boyer BB, Dillard D, Woodahl EL, Whitener R, Thummel KE, Burke W. Ethical issues in developing pharmacogenetic research partnerships with American indigenous communities. Clin Pharmacol Ther 2011; 89: 343-345
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 343-345
    • Boyer, B.B.1    Dillard, D.2    Woodahl, E.L.3    Whitener, R.4    Thummel, K.E.5    Burke, W.6
  • 5
    • 33745347897 scopus 로고    scopus 로고
    • Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: Implication for optimization of breast cancer treatment
    • Borges S, Desta Z, Li L, Skaar TC, Ward BA, Nguyen A, et al. Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: implication for optimization of breast cancer treatment. Clin Pharmacol Ther 2006; 80:61-74
    • (2006) Clin Pharmacol Ther , vol.80 , pp. 61-74
    • Borges, S.1    Desta, Z.2    Li, L.3    Skaar, T.C.4    Ward, B.A.5    Nguyen, A.6
  • 6
    • 37549006389 scopus 로고    scopus 로고
    • Tamoxifen pharmacogenomics: The role of CYP2D6 as a predictor of drug response
    • Goetz MP, Kamal A, Ames MM. Tamoxifen pharmacogenomics: the role of CYP2D6 as a predictor of drug response. Clin Pharmacol Ther 2008; 83:160-166
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 160-166
    • Goetz, M.P.1    Kamal, A.2    Ames, M.M.3
  • 7
    • 44049098957 scopus 로고    scopus 로고
    • A model citizen? Is tamoxifen more effective than aromatase inhibitors if we pick the right patients?
    • Hayes DF, Stearns V, Rae J, Flockhart D. A model citizen? Is tamoxifen more effective than aromatase inhibitors if we pick the right patients? J Natl Cancer Inst 2008; 100:610-613
    • (2008) J Natl Cancer Inst , vol.100 , pp. 610-613
    • Hayes, D.F.1    Stearns, V.2    Rae, J.3    Flockhart, D.4
  • 8
    • 19944434201 scopus 로고    scopus 로고
    • CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment
    • Jin Y, Desta Z, Stearns V,Ward B, Ho H, Lee KH, et al. CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment. J Natl Cancer Inst 2005; 97:30-39
    • (2005) J Natl Cancer Inst , vol.97 , pp. 30-39
    • Jin, Y.1    Desta, Z.2    Stearns, V.3    Ward, B.4    Ho, H.5    Lee, K.H.6
  • 9
    • 34548532227 scopus 로고    scopus 로고
    • Clinical implications of CYP2D6 genotypes predictive of tamoxifen pharmacokinetics in metastatic breast cancer
    • Lim HS, Ju Lee H, Seok Lee K, Sook Lee E, Jang IJ, Ro J. Clinical implications of CYP2D6 genotypes predictive of tamoxifen pharmacokinetics in metastatic breast cancer. J Clin Oncol 2007; 25: 3837-3845
    • (2007) J Clin Oncol , vol.25 , pp. 3837-3845
    • Lim, H.S.1    Ju Lee, H.2    Seok Lee, K.3    Sook Lee, E.4    Jang, I.J.5    Ro, J.6
  • 10
    • 79955480679 scopus 로고    scopus 로고
    • Activity levels of tamoxifen metabolites at the estrogen receptor and the impact of genetic polymorphisms of phase i and II enzymes on their concentration levels in plasma
    • Murdter TE, Schroth W, Bacchus-Gerybadze L, Winter S, Heinkele G, Simon W, et al. Activity levels of tamoxifen metabolites at the estrogen receptor and the impact of genetic polymorphisms of phase I and II enzymes on their concentration levels in plasma. Clin Pharmacol Ther 2011; 89: 708-717
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 708-717
    • Murdter, T.E.1    Schroth, W.2    Bacchus-Gerybadze, L.3    Winter, S.4    Heinkele, G.5    Simon, W.6
  • 11
    • 70349929431 scopus 로고    scopus 로고
    • Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen
    • Schroth W, Goetz MP, Hamann U, Fasching PA, Schmidt M,Winter S, et al. Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen. JAMA 2009; 302:1429-1436
    • (2009) JAMA , vol.302 , pp. 1429-1436
    • Schroth, W.1    Goetz, M.P.2    Hamann, U.3    Fasching, P.A.4    Schmidt, M.5    Winter, S.6
  • 12
    • 57049117843 scopus 로고    scopus 로고
    • Pharmacogenetics and breast cancer endocrine therapy: CYP2D6 as a predictive factor for tamoxifen metabolism and drug response?
    • Stearns V, Rae JM. Pharmacogenetics and breast cancer endocrine therapy: CYP2D6 as a predictive factor for tamoxifen metabolism and drug response? Expert Rev Mol Med 2008; 10:e34
    • (2008) Expert Rev Mol Med , vol.10
    • Stearns, V.1    Rae, J.M.2
  • 14
    • 73549100850 scopus 로고    scopus 로고
    • CYP2D7-2D6 hybrid tandems: Identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction
    • Gaedigk A, Fuhr U, Johnson C, Berard LA, Bradford D, Leeder JS. CYP2D7-2D6 hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction. Pharmacogenomics 2010; 11:43-53
    • (2010) Pharmacogenomics , vol.11 , pp. 43-53
    • Gaedigk, A.1    Fuhr, U.2    Johnson, C.3    Berard, L.A.4    Bradford, D.5    Leeder, J.S.6
  • 16
    • 84864916868 scopus 로고    scopus 로고
    • CYP2D6 update: Revised nomenclature for CYP2D7/2D6 hybrid genes
    • Sim SC, Daly AK, Gaedigk A. CYP2D6 update: revised nomenclature for CYP2D7/2D6 hybrid genes. Pharmacogenet Genomics 2012; 22: 692-694
    • (2012) Pharmacogenet Genomics , vol.22 , pp. 692-694
    • Sim, S.C.1    Daly, A.K.2    Gaedigk, A.3
  • 17
    • 82755166898 scopus 로고    scopus 로고
    • From pharmacogenomic knowledge acquisition to clinical applications: The PharmGKB as a clinical pharmacogenomic biomarker resource
    • McDonagh EM, Whirl-Carrillo M, Garten Y, Altman RB, Klein TE. From pharmacogenomic knowledge acquisition to clinical applications: the PharmGKB as a clinical pharmacogenomic biomarker resource. Biomark Med 2011; 5:795-806
    • (2011) Biomark Med , vol.5 , pp. 795-806
    • McDonagh, E.M.1    Whirl-Carrillo, M.2    Garten, Y.3    Altman, R.B.4    Klein, T.E.5
  • 18
  • 19
    • 0035071598 scopus 로고    scopus 로고
    • Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
    • Kuehl P, Zhang J, Lin Y, Lamba J, Assem M, Schuetz J, et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat Genet 2001; 27:383-391
    • (2001) Nat Genet , vol.27 , pp. 383-391
    • Kuehl, P.1    Zhang, J.2    Lin, Y.3    Lamba, J.4    Assem, M.5    Schuetz, J.6
  • 21
    • 34247371529 scopus 로고    scopus 로고
    • Effect of CYP3A5 expression on vincristine metabolism with human liver microsomes
    • Dennison JB, Jones DR, Renbarger JL, Hall SD. Effect of CYP3A5 expression on vincristine metabolism with human liver microsomes. J Pharmacol Exp Ther 2007; 321:553-563
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 553-563
    • Dennison, J.B.1    Jones, D.R.2    Renbarger, J.L.3    Hall, S.D.4
  • 23
    • 0036089341 scopus 로고    scopus 로고
    • Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism
    • Lin YS, Dowling AL, Quigley SD, Farin FM, Zhang J, Lamba J, et al. Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism. Mol Pharmacol 2002; 62:162-172
    • (2002) Mol Pharmacol , vol.62 , pp. 162-172
    • Lin, Y.S.1    Dowling, A.L.2    Quigley, S.D.3    Farin, F.M.4    Zhang, J.5    Lamba, J.6
  • 25
    • 0041831261 scopus 로고    scopus 로고
    • Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus
    • Hesselink DA, van Schaik RH, van der Heiden IP, van der Werf M, Gregoor PJ, Lindemans J, et al. Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus. Clin Pharmacol Ther 2003; 74:245-254
    • (2003) Clin Pharmacol Ther , vol.74 , pp. 245-254
    • Hesselink, D.A.1    Van Schaik, R.H.2    Van Der Heiden, I.P.3    Van Der Werf, M.4    Gregoor, P.J.5    Lindemans, J.6
  • 27
    • 0033861614 scopus 로고    scopus 로고
    • CYP3A activity in African American and European American men: Population differences and functional effect of the CYP3A4*1B50-promoter region polymorphism
    • Wandel C, Witte JS, Hall JM, Stein CM, Wood AJ, Wilkinson GR. CYP3A activity in African American and European American men: population differences and functional effect of the CYP3A4*1B50-promoter region polymorphism. Clin Pharmacol Ther 2000; 68:82-91
    • (2000) Clin Pharmacol Ther , vol.68 , pp. 82-91
    • Wandel, C.1    Witte, J.S.2    Hall, J.M.3    Stein, C.M.4    Wood, A.J.5    Wilkinson, G.R.6
  • 29
    • 27544486754 scopus 로고    scopus 로고
    • Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles
    • Rodriguez-Antona C, Sayi JG, Gustafsson LL, Bertilsson L, Ingelman- Sundberg M. Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles. Biochem Biophys Res Commun 2005; 338:299-305
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 299-305
    • Rodriguez-Antona, C.1    Sayi, J.G.2    Gustafsson, L.L.3    Bertilsson, L.4    Ingelman- Sundberg, M.5
  • 30
    • 80054090832 scopus 로고    scopus 로고
    • Effect of CYP3A4*1G on the fentanyl consumption for intravenous patient-controlled analgesia after total abdominal hysterectomy in Chinese Han population
    • Dong ZL, Li H, Chen QX, Hu Y,Wu SJ, Tang LY, et al. Effect of CYP3A4*1G on the fentanyl consumption for intravenous patient-controlled analgesia after total abdominal hysterectomy in Chinese Han population. J Clin Pharm Ther 2012; 37:153-156
    • (2012) J Clin Pharm Ther , vol.37 , pp. 153-156
    • Dong, Z.L.1    Li, H.2    Chen, Q.X.3    Hu, Y.4    Wu, S.J.5    Tang, L.Y.6
  • 31
    • 50849097843 scopus 로고    scopus 로고
    • CYP3A4*1G polymorphism is associated with lipid-lowering efficacy of atorvastatin but not of simvastatin
    • Gao Y, Zhang LR, Fu Q. CYP3A4*1G polymorphism is associated with lipid-lowering efficacy of atorvastatin but not of simvastatin. Eur J Clin Pharmacol 2008; 64:877-882
    • (2008) Eur J Clin Pharmacol , vol.64 , pp. 877-882
    • Gao, Y.1    Zhang, L.R.2    Fu, Q.3
  • 32
    • 79960810087 scopus 로고    scopus 로고
    • Impact of the CYP3A4*1G polymorphism and its combination with CYP3A5 genotypes on tacrolimus pharmacokinetics in renal transplant patients
    • Miura M, Satoh S, Kagaya H, Saito M, Numakura K, Tsuchiya N, et al. Impact of the CYP3A4*1G polymorphism and its combination with CYP3A5 genotypes on tacrolimus pharmacokinetics in renal transplant patients. Pharmacogenomics 2011; 12:977-984
    • (2011) Pharmacogenomics , vol.12 , pp. 977-984
    • Miura, M.1    Satoh, S.2    Kagaya, H.3    Saito, M.4    Numakura, K.5    Tsuchiya, N.6
  • 33
    • 79951770289 scopus 로고    scopus 로고
    • Impact of CYP3A4*1G polymorphism on metabolism of fentanyl in Chinese patients undergoing lower abdominal surgery
    • Yuan R, Zhang X, Deng Q, Wu Y, Xiang G. Impact of CYP3A4*1G polymorphism on metabolism of fentanyl in Chinese patients undergoing lower abdominal surgery. Clin Chim Acta 2011; 412:755-760
    • (2011) Clin Chim Acta , vol.412 , pp. 755-760
    • Yuan, R.1    Zhang, X.2    Deng, Q.3    Wu, Y.4    Xiang, G.5
  • 34
    • 76949108596 scopus 로고    scopus 로고
    • CYP3A4*1G genetic polymorphism influences CYP3A activity and response to fentanyl in Chinese gynecologic patients
    • Zhang W, Chang YZ, Kan QC, Zhang LR, Li ZS, Lu H, et al. CYP3A4*1G genetic polymorphism influences CYP3A activity and response to fentanyl in Chinese gynecologic patients. Eur J Clin Pharmacol 2010; 66:61-66
    • (2010) Eur J Clin Pharmacol , vol.66 , pp. 61-66
    • Zhang, W.1    Chang, Y.Z.2    Kan, Q.C.3    Zhang, L.R.4    Li, Z.S.5    Lu, H.6
  • 35
    • 79953849214 scopus 로고    scopus 로고
    • Influence of CYP3A5*3 polymorphism and interaction between CYP3A5*3 and CYP3A4*1G polymorphisms on post-operative fentanyl analgesia in Chinese patients undergoing gynaecological surgery
    • Zhang W, Yuan JJ, Kan QC, Zhang LR, Chang YZ,Wang ZY, et al. Influence of CYP3A5*3 polymorphism and interaction between CYP3A5*3 and CYP3A4*1G polymorphisms on post-operative fentanyl analgesia in Chinese patients undergoing gynaecological surgery. Eur J Anaesthesiol 2011; 28:245-250
    • (2011) Eur J Anaesthesiol , vol.28 , pp. 245-250
    • Zhang, W.1    Yuan, J.J.2    Kan, Q.C.3    Zhang, L.R.4    Chang, Y.Z.5    Wang, Z.Y.6
  • 36
    • 81055140354 scopus 로고    scopus 로고
    • Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study
    • Elens L, Becker ML, Haufroid V, Hofman A, Visser LE, Uitterlinden AG, et al. Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study. Pharmacogenet Genomics 2011; 21:861-866
    • (2011) Pharmacogenet Genomics , vol.21 , pp. 861-866
    • Elens, L.1    Becker, M.L.2    Haufroid, V.3    Hofman, A.4    Visser, L.E.5    Uitterlinden, A.G.6
  • 37
    • 80054924410 scopus 로고    scopus 로고
    • A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients
    • Elens L, Bouamar R, Hesselink DA, Haufroid V, van der Heiden IP, van Gelder T, et al. A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients. Clin Chem 2011; 57:1574-1583
    • (2011) Clin Chem , vol.57 , pp. 1574-1583
    • Elens, L.1    Bouamar, R.2    Hesselink, D.A.3    Haufroid, V.4    Van Der Heiden, I.P.5    Van Gelder, T.6
  • 38
    • 84859900517 scopus 로고    scopus 로고
    • The new CYP3A4 intron 6 C> T polymorphism (CYP3A4*22) is associated with an increased risk of delayed graft function and worse renal function in cyclosporine-treated kidney transplant patients
    • Elens L, Bouamar R, Hesselink DA, Haufroid V, van Gelder T, van Schaik RH. The new CYP3A4 intron 6 C> T polymorphism (CYP3A4*22) is associated with an increased risk of delayed graft function and worse renal function in cyclosporine-treated kidney transplant patients. Pharmacogenet Genomics 2012; 22:373-380
    • (2012) Pharmacogenet Genomics , vol.22 , pp. 373-380
    • Elens, L.1    Bouamar, R.2    Hesselink, D.A.3    Haufroid, V.4    Van Gelder, T.5    Van Schaik, R.H.6
  • 39
    • 79960633918 scopus 로고    scopus 로고
    • Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs
    • Wang D, Guo Y,Wrighton SA, Cooke GE, Sadee W. Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs. Pharmacogenomics J 2011; 11:274-286
    • (2011) Pharmacogenomics J , vol.11 , pp. 274-286
    • Wang, D.1    Guo, Y.2    Wrighton, S.A.3    Cooke, G.E.4    Sadee, W.5
  • 40
    • 0033065223 scopus 로고    scopus 로고
    • A common genetic basis for idiosyncratic toxicity of warfarin and phenytoin
    • Rettie AE, Haining RL, Bajpai M, Levy RH. A common genetic basis for idiosyncratic toxicity of warfarin and phenytoin. Epilepsy Res 1999; 35: 253-255
    • (1999) Epilepsy Res , vol.35 , pp. 253-255
    • Rettie, A.E.1    Haining, R.L.2    Bajpai, M.3    Levy, R.H.4
  • 41
    • 41549109042 scopus 로고    scopus 로고
    • Cytochrome p450 enzyme polymorphism frequency in indigenous and Native American populations: A systematic review
    • Jaja C, Burke W, Thummel K, Edwards K, Veenstra DL. Cytochrome p450 enzyme polymorphism frequency in indigenous and Native American populations: a systematic review. Community Genet 2008; 11:141-149
    • (2008) Community Genet , vol.11 , pp. 141-149
    • Jaja, C.1    Burke, W.2    Thummel, K.3    Edwards, K.4    Veenstra, D.L.5
  • 42
    • 84880918696 scopus 로고    scopus 로고
    • Pharmacogenomics Knowledge Base (PharmGKB) [Accessed 5 October 2012]
    • Pharmacogenomics Knowledge Base (PharmGKB). CYP2D6 allele frequency table. Available at: http://www.pharmgkb.org/ download.action?filename =CYP2D6-allele-frequency-table.xlsx [Accessed 5 October 2012]
    • CYP2D6 Allele Frequency Table
  • 43
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Consortium The International HapMap Project
    • The International HapMap Consortium. The International HapMap Project. Nature 2003; 426:789-796
    • (2003) Nature , vol.426 , pp. 789-796
  • 44
    • 0032810509 scopus 로고    scopus 로고
    • Comparative evolutionary pharmacogenetics of CYP2D6 in Ngawbe and Embera Amerindians of Panama and Colombia: Role of selection versus drift in world populations
    • Jorge LF, Eichelbaum M, Griese EU, Inaba T, Arias TD. Comparative evolutionary pharmacogenetics of CYP2D6 in Ngawbe and Embera Amerindians of Panama and Colombia: role of selection versus drift in world populations. Pharmacogenetics 1999; 9:217-228
    • (1999) Pharmacogenetics , vol.9 , pp. 217-228
    • Jorge, L.F.1    Eichelbaum, M.2    Griese, E.U.3    Inaba, T.4    Arias, T.D.5
  • 45
    • 34547665041 scopus 로고    scopus 로고
    • CYP3A5*3 and CYP3A4*1B allele distribution and genotype combinations: Differences between Spaniards and Central Americans
    • Sinues B, Vicente J, Fanlo A, Vasquez P, Medina JC, Mayayo E, et al. CYP3A5*3 and CYP3A4*1B allele distribution and genotype combinations: differences between Spaniards and Central Americans. Ther Drug Monit 2007; 29:412-416
    • (2007) Ther Drug Monit , vol.29 , pp. 412-416
    • Sinues, B.1    Vicente, J.2    Fanlo, A.3    Vasquez, P.4    Medina, J.C.5    Mayayo, E.6
  • 46
    • 33846195001 scopus 로고    scopus 로고
    • Allele and genotype frequencies of metabolic genes in Native Americans from Argentina and Paraguay
    • Bailliet G, Santos MR, Alfaro EL, Dipierri JE, Demarchi DA, Carnese FR, et al. Allele and genotype frequencies of metabolic genes in Native Americans from Argentina and Paraguay. Mutat Res 2007; 627:171-177
    • (2007) Mutat Res , vol.627 , pp. 171-177
    • Bailliet, G.1    Santos, M.R.2    Alfaro, E.L.3    Dipierri, J.E.4    Demarchi, D.A.5    Carnese, F.R.6
  • 49
    • 0034469337 scopus 로고    scopus 로고
    • Isolation, sequence and genotyping of the drug metabolizer CYP2D6 gene in the Colombian population
    • Isaza CA, Henao J, Lopez AM, Cacabelos R. Isolation, sequence and genotyping of the drug metabolizer CYP2D6 gene in the Colombian population. Methods Find Exp Clin Pharmacol 2000; 22:695-705
    • (2000) Methods Find Exp Clin Pharmacol , vol.22 , pp. 695-705
    • Isaza, C.A.1    Henao, J.2    Lopez, A.M.3    Cacabelos, R.4
  • 51
    • 27944474000 scopus 로고    scopus 로고
    • CYP2D6 genotype and phenotype determination in a Mexican Mestizo population
    • Lopez M, Guerrero J, Jung-Cook H, Alonso ME. CYP2D6 genotype and phenotype determination in a Mexican Mestizo population. Eur J Clin Pharmacol 2005; 61:749-754
    • (2005) Eur J Clin Pharmacol , vol.61 , pp. 749-754
    • Lopez, M.1    Guerrero, J.2    Jung-Cook, H.3    Alonso, M.E.4
  • 53
    • 0030985006 scopus 로고    scopus 로고
    • CYP2D6 phenotype and genotype in a Canadian Native Indian population
    • Nowak MP, Tyndale RF, Sellers EM. CYP2D6 phenotype and genotype in a Canadian Native Indian population. Pharmacogenetics 1997; 7:145-148
    • (1997) Pharmacogenetics , vol.7 , pp. 145-148
    • Nowak, M.P.1    Tyndale, R.F.2    Sellers, E.M.3
  • 54
    • 77953947158 scopus 로고    scopus 로고
    • Influence of CYP2D6 deletion, multiplication, - 1584C- >g, 31G- > A and 2988G- > a gene polymorphisms on dextromethorphan metabolism among Mexican tepehuanos and mestizos
    • Sosa-Macias M, Dorado P, Alanis-Banuelos RE, Llerena A, Lares-Asseff I. Influence of CYP2D6 deletion, multiplication, - 1584C- >G, 31G- > A and 2988G- > a gene polymorphisms on dextromethorphan metabolism among Mexican tepehuanos and mestizos. Pharmacology 2010; 86:30-36
    • (2010) Pharmacology , vol.86 , pp. 30-36
    • Sosa-Macias, M.1    Dorado, P.2    Alanis-Banuelos, R.E.3    Llerena, A.4    Lares-Asseff, I.5
  • 58
    • 0032906340 scopus 로고    scopus 로고
    • Sequence variation in the human angiotensin converting enzyme
    • Rieder MJ, Taylor SL, Clark AG, Nickerson DA. Sequence variation in the human angiotensin converting enzyme. Nat Genet 1999; 22:59-62
    • (1999) Nat Genet , vol.22 , pp. 59-62
    • Rieder, M.J.1    Taylor, S.L.2    Clark, A.G.3    Nickerson, D.A.4
  • 59
    • 0030872838 scopus 로고    scopus 로고
    • PolyPhred: Automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing
    • Nickerson DA, Tobe VO, Taylor SL. PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing. Nucleic Acids Res 1997; 25:2745-2751
    • (1997) Nucleic Acids Res , vol.25 , pp. 2745-2751
    • Nickerson, D.A.1    Tobe, V.O.2    Taylor, S.L.3
  • 60
    • 33644624797 scopus 로고    scopus 로고
    • Automating sequence-based detection and genotyping of SNPs from diploid samples
    • Stephens M, Sloan JS, Robertson PD, Scheet P, Nickerson DA. Automating sequence-based detection and genotyping of SNPs from diploid samples. Nat Genet 2006; 38:375-381
    • (2006) Nat Genet , vol.38 , pp. 375-381
    • Stephens, M.1    Sloan, J.S.2    Robertson, P.D.3    Scheet, P.4    Nickerson, D.A.5
  • 61
    • 0031978181 scopus 로고    scopus 로고
    • Base-calling of automated sequencer traces using phred. II. Error probabilities
    • Ewing B, Green P. Base-calling of automated sequencer traces using phred. II. Error probabilities. Genome Res 1998; 8:186-194
    • (1998) Genome Res , vol.8 , pp. 186-194
    • Ewing, B.1    Green, P.2
  • 63
    • 33644974019 scopus 로고    scopus 로고
    • A fast and flexible statistical model for large-scale population genotype data: Applications to inferring missing genotypes and haplotypic phase
    • Scheet P, Stephens M. A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase. Am J Hum Genet 2006; 78:629-644
    • (2006) Am J Hum Genet , vol.78 , pp. 629-644
    • Scheet, P.1    Stephens, M.2
  • 65
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21:263-265
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 67
    • 0030860004 scopus 로고    scopus 로고
    • Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: Characterization of 48 mutations and 53 alleles, their frequencies and evolution
    • Marez D, Legrand M, Sabbagh N, Lo Guidice JM, Spire C, Lafitte JJ, et al. Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution. Pharmacogenetics 1997; 7:193-202
    • (1997) Pharmacogenetics , vol.7 , pp. 193-202
    • Marez, D.1    Legrand, M.2    Sabbagh, N.3    Lo Guidice, J.M.4    Spire, C.5    Lafitte, J.J.6
  • 69
    • 84855968708 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype
    • Crews KR, Gaedigk A, Dunnenberger HM, Klein TE, Shen DD, Callaghan JT, et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype. Clin Pharmacol Ther 2012; 91:321-326
    • (2012) Clin Pharmacol Ther , vol.91 , pp. 321-326
    • Crews, K.R.1    Gaedigk, A.2    Dunnenberger, H.M.3    Klein, T.E.4    Shen, D.D.5    Callaghan, J.T.6
  • 70
    • 84876665512 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants
    • Hicks JK, Swen JJ, Thorn CF, Sangkuhl K, Kharasch ED, Ellingrod VL, et al. Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants. Clin Pharmacol Ther 2013; 93:402-408
    • (2013) Clin Pharmacol Ther , vol.93 , pp. 402-408
    • Hicks, J.K.1    Swen, J.J.2    Thorn, C.F.3    Sangkuhl, K.4    Kharasch, E.D.5    Ellingrod, V.L.6
  • 71
    • 83155192317 scopus 로고    scopus 로고
    • Novel variant of CYP2D6*6 is undetected by a commonly used genotyping procedure
    • Rasmussen HB, Werge T. Novel variant of CYP2D6*6 is undetected by a commonly used genotyping procedure. Pharmacol Rep 2011; 63: 1264-1266
    • (2011) Pharmacol Rep , vol.63 , pp. 1264-1266
    • Rasmussen, H.B.1    Werge, T.2
  • 72
    • 65249102147 scopus 로고    scopus 로고
    • Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects
    • Matimba A, Del-Favero J, Van Broeckhoven C, Masimirembwa C. Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects. Hum Genomics 2009; 3:169-190
    • (2009) Hum Genomics , vol.3 , pp. 169-190
    • Matimba, A.1    Del-Favero, J.2    Van Broeckhoven, C.3    Masimirembwa, C.4
  • 73
    • 0027136288 scopus 로고
    • Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
    • Johansson I, Lundqvist E, Bertilsson L, Dahl ML, Sjoqvist F, Ingelman- Sundberg M. Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc Natl Acad Sci USA 1993; 90:11825-11829
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11825-11829
    • Johansson, I.1    Lundqvist, E.2    Bertilsson, L.3    Dahl, M.L.4    Sjoqvist, F.5    Ingelman-Sundberg, M.6
  • 74
    • 0033790979 scopus 로고    scopus 로고
    • Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6
    • Raimundo S, Fischer J, Eichelbaum M, Griese EU, Schwab M, Zanger UM. Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6. Pharmacogenetics 2000; 10:577-581
    • (2000) Pharmacogenetics , vol.10 , pp. 577-581
    • Raimundo, S.1    Fischer, J.2    Eichelbaum, M.3    Griese, E.U.4    Schwab, M.5    Zanger, U.M.6
  • 76
    • 36148976077 scopus 로고    scopus 로고
    • Influence of cytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspects
    • Ingelman-Sundberg M, Sim SC, Gomez A, Rodriguez-Antona C. Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects. Pharmacol Ther 2007; 116: 496-526
    • (2007) Pharmacol Ther , vol.116 , pp. 496-526
    • Ingelman-Sundberg, M.1    Sim, S.C.2    Gomez, A.3    Rodriguez-Antona, C.4
  • 78
    • 84880921065 scopus 로고    scopus 로고
    • NIEHS Environmental Genome Project University Of Washington Seattle WA. [Accessed 5 October 2012]
    • NIEHS SNPs. NIEHS Environmental Genome Project, University of Washington, Seattle, WA. Available at: http://egp.gs.washington.edu [Accessed 5 October 2012]
    • NIEHS SNPs
  • 79
    • 54349116753 scopus 로고    scopus 로고
    • Drug interactions and pharmacogenomics in the treatment of breast cancer and depression
    • Henry NL, Stearns V, Flockhart DA, Hayes DF, Riba M. Drug interactions and pharmacogenomics in the treatment of breast cancer and depression. Am J Psychiatry 2008; 165:1251-1255
    • (2008) Am J Psychiatry , vol.165 , pp. 1251-1255
    • Henry, N.L.1    Stearns, V.2    Flockhart, D.A.3    Hayes, D.F.4    Riba, M.5
  • 81
    • 34249034315 scopus 로고    scopus 로고
    • Identification and characterization of CYP2D6*56B, an allele associated with the poor metabolizer phenotype
    • Gaedigk A, Eklund JD, Pearce RE, Leeder JS, Alander SW, Phillips MS, et al. Identification and characterization of CYP2D6*56B, an allele associated with the poor metabolizer phenotype. Clin Pharmacol Ther 2007; 81:817-820
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 817-820
    • Gaedigk, A.1    Eklund, J.D.2    Pearce, R.E.3    Leeder, J.S.4    Alander, S.W.5    Phillips, M.S.6
  • 82
    • 57849102018 scopus 로고    scopus 로고
    • Identification of a novel non-functional CYP2D6 allele, CYP2D6*69, in a Caucasian poor metabolizer individual
    • Gaedigk A, Frank D, Fuhr U. Identification of a novel non-functional CYP2D6 allele, CYP2D6*69, in a Caucasian poor metabolizer individual. Eur J Clin Pharmacol 2009; 65:97-100
    • (2009) Eur J Clin Pharmacol , vol.65 , pp. 97-100
    • Gaedigk, A.1    Frank, D.2    Fuhr, U.3
  • 83
    • 8544221912 scopus 로고    scopus 로고
    • CYP3A4, CYP3A5, and CYP3A43 genotypes and haplotypes in the etiology and severity of prostate cancer
    • Zeigler-Johnson C, Friebel T,Walker AH,Wang Y, Spangler E, Panossian S, et al. CYP3A4, CYP3A5, and CYP3A43 genotypes and haplotypes in the etiology and severity of prostate cancer. Cancer Res 2004; 64: 8461-8467
    • (2004) Cancer Res , vol.64 , pp. 8461-8467
    • Zeigler-Johnson, C.1    Friebel, T.2    Walker, A.H.3    Wang, Y.4    Spangler, E.5    Panossian, S.6
  • 84
    • 80054723852 scopus 로고    scopus 로고
    • Pharmacokinetic differences corroborate observed low tacrolimus dosage in Native American renal transplant patients
    • Grover A, Frassetto LA, Benet LZ, Chakkera HA. Pharmacokinetic differences corroborate observed low tacrolimus dosage in Native American renal transplant patients. Drug Metab Dispos 2011; 39: 2017-2019
    • (2011) Drug Metab Dispos , vol.39 , pp. 2017-2019
    • Grover, A.1    Frassetto, L.A.2    Benet, L.Z.3    Chakkera, H.A.4
  • 86
    • 2942655651 scopus 로고    scopus 로고
    • Best linear unbiased allele-frequency estimation in complex pedigrees
    • McPeek MS, Wu X, Ober C. Best linear unbiased allele-frequency estimation in complex pedigrees. Biometrics 2004; 60:359-367.
    • (2004) Biometrics , vol.60 , pp. 359-367
    • McPeek, M.S.1    Wu, X.2    Ober, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.