CYP3A4*1G genetic polymorphism influences CYP3A activity and response to fentanyl in Chinese gynecologic patients

European Journal of Clinical Pharmacology

Volumn 66, Issue 1, 2010, Pages 61-66

  Zhang, Wei ^a   Chang, Yan Zi ^a   Kan, Quan Cheng ^a   Zhang, Li Rong ^b   Li, Zhi Song ^a   Lu, Hui ^a   Wang, Zhong Yu ^a   Chu, Qin Jun ^a   Zhang, Jie ^a  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^b ZHENGZHOU UNIVERSITY   (China)

Author keywords

Analgesia; CYP3A; Fentanyl; Phenotype; Polymorphisms

Indexed keywords

ALPHA HYDROXYMIDAZOLAM; CYTOCHROME P450 3A; FENTANYL; MIDAZOLAM; 1-HYDROXYMETHYLMIDAZOLAM; CYP3A4 PROTEIN, HUMAN; DRUG DERIVATIVE; NARCOTIC ANALGESIC AGENT;

ABDOMINAL HYSTERECTOMY; ADULT; ALLELE; ARTICLE; CHINESE; CORRELATION ANALYSIS; CYP3A4 GENE; DRUG RESPONSE; DRUG USE; ENZYME ACTIVITY; FEMALE; GENE; GENE FREQUENCY; GENERAL ANESTHESIA; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MYOMECTOMY; PATIENT CONTROLLED ANALGESIA; PHARMACOGENETICS; PHENOTYPE; POLYMERASE CHAIN REACTION; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; VISUAL ANALOG SCALE; ASIAN; BLOOD; CHINA; ENZYMOLOGY; GENETICS; GYNECOLOGIC SURGERY; INTRAVENOUS DRUG ADMINISTRATION; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS, OPIOID; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; CYTOCHROME P-450 CYP3A; FEMALE; FENTANYL; GENE FREQUENCY; GENOTYPE; GYNECOLOGIC SURGICAL PROCEDURES; HUMANS; INFUSIONS, INTRAVENOUS; MIDAZOLAM; PAIN, POSTOPERATIVE; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 76949108596     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-009-0726-4     Document Type: Article

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