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Volumn 8, Issue 7, 2013, Pages

STAT3 Signaling Induces the Differentiation of Human ICOS+ CD4 T Cells Helping B lymphocytes

Author keywords

[No Author keywords available]

Indexed keywords

INDUCIBLE T CELL COSTIMULATOR; INTERLEUKIN 21; INTERLEUKIN 27; INTERLEUKIN 6; STAT3 PROTEIN;

EID: 84880801512     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071029     Document Type: Article
Times cited : (16)

References (44)
  • 2
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas AK, Murphy KM, Sher A, (1996) Functional diversity of helper T lymphocytes. Nature 383: 787-793.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 3
    • 0032033419 scopus 로고    scopus 로고
    • Cytokines induce the development of functionally heterogeneous T helper cell subsets
    • O'Garra A, (1998) Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity 8: 275-283.
    • (1998) Immunity , vol.8 , pp. 275-283
    • O'Garra, A.1
  • 4
    • 0034606359 scopus 로고    scopus 로고
    • Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production
    • Breitfeld D, Ohl L, Kremmer E, Ellwart J, Sallusto F, et al. (2000) Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production. J Exp Med 192: 1545-1552.
    • (2000) J Exp Med , vol.192 , pp. 1545-1552
    • Breitfeld, D.1    Ohl, L.2    Kremmer, E.3    Ellwart, J.4    Sallusto, F.5
  • 5
    • 0035908122 scopus 로고    scopus 로고
    • Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells
    • Kim CH, Rott LS, Clark-Lewis I, Campbell DJ, Wu L, et al. (2001) Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells. J Exp Med 193: 1373-1381.
    • (2001) J Exp Med , vol.193 , pp. 1373-1381
    • Kim, C.H.1    Rott, L.S.2    Clark-Lewis, I.3    Campbell, D.J.4    Wu, L.5
  • 6
    • 0034606348 scopus 로고    scopus 로고
    • CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function
    • Schaerli P, Willimann K, Lang AB, Lipp M, Loetscher P, et al. (2000) CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function. J Exp Med 192: 1553-1562.
    • (2000) J Exp Med , vol.192 , pp. 1553-1562
    • Schaerli, P.1    Willimann, K.2    Lang, A.B.3    Lipp, M.4    Loetscher, P.5
  • 7
    • 0034661356 scopus 로고    scopus 로고
    • Lineage commitment in the immune system: the T helper lymphocyte grows up
    • Glimcher LH, Murphy KM, (2000) Lineage commitment in the immune system: the T helper lymphocyte grows up. Genes Dev 14: 1693-1711.
    • (2000) Genes Dev , vol.14 , pp. 1693-1711
    • Glimcher, L.H.1    Murphy, K.M.2
  • 9
    • 0034677646 scopus 로고    scopus 로고
    • A novel transcription factor, T-bet, directs Th1 lineage commitment
    • Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, et al. (2000) A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100: 655-669.
    • (2000) Cell , vol.100 , pp. 655-669
    • Szabo, S.J.1    Kim, S.T.2    Costa, G.L.3    Zhang, X.4    Fathman, C.G.5
  • 10
    • 0345358584 scopus 로고    scopus 로고
    • The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses
    • Trinchieri G, Pflanz S, Kastelein RA, (2003) The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses. Immunity 19: 641-644.
    • (2003) Immunity , vol.19 , pp. 641-644
    • Trinchieri, G.1    Pflanz, S.2    Kastelein, R.A.3
  • 11
    • 0030810155 scopus 로고    scopus 로고
    • The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
    • Zheng W, Flavell RA, (1997) The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89: 587-596.
    • (1997) Cell , vol.89 , pp. 587-596
    • Zheng, W.1    Flavell, R.A.2
  • 12
    • 60549105041 scopus 로고    scopus 로고
    • The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells
    • Dienz O, Eaton SM, Bond JP, Neveu W, Moquin D, et al. (2009) The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells. J Exp Med 206: 69-78.
    • (2009) J Exp Med , vol.206 , pp. 69-78
    • Dienz, O.1    Eaton, S.M.2    Bond, J.P.3    Neveu, W.4    Moquin, D.5
  • 13
    • 63849275584 scopus 로고    scopus 로고
    • Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities
    • Eddahri F, Denanglaire S, Bureau F, Spolski R, Leonard WJ, et al. (2009) Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities. Blood 113: 2426-2433.
    • (2009) Blood , vol.113 , pp. 2426-2433
    • Eddahri, F.1    Denanglaire, S.2    Bureau, F.3    Spolski, R.4    Leonard, W.J.5
  • 14
    • 79952637807 scopus 로고    scopus 로고
    • IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation
    • Eto D, Lao C, DiToro D, Barnett B, Escobar TC, et al. (2011) IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation. PLoS One 6: e17739.
    • (2011) PLoS One , vol.6
    • Eto, D.1    Lao, C.2    DiToro, D.3    Barnett, B.4    Escobar, T.C.5
  • 15
    • 46749151286 scopus 로고    scopus 로고
    • Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
    • Nurieva RI, Chung Y, Hwang D, Yang XO, Kang HS, et al. (2008) Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity 29: 138-149.
    • (2008) Immunity , vol.29 , pp. 138-149
    • Nurieva, R.I.1    Chung, Y.2    Hwang, D.3    Yang, X.O.4    Kang, H.S.5
  • 16
    • 70450265288 scopus 로고    scopus 로고
    • Early commitment of naive human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12
    • Ma CS, Suryani S, Avery DT, Chan A, Nanan R, et al. (2009) Early commitment of naive human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12. Immunol Cell Biol 87: 590-600.
    • (2009) Immunol Cell Biol , vol.87 , pp. 590-600
    • Ma, C.S.1    Suryani, S.2    Avery, D.T.3    Chan, A.4    Nanan, R.5
  • 17
    • 68249158536 scopus 로고    scopus 로고
    • Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12
    • Schmitt N, Morita R, Bourdery L, Bentebibel SE, Zurawski SM, et al. (2009) Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12. Immunity 31: 158-169.
    • (2009) Immunity , vol.31 , pp. 158-169
    • Schmitt, N.1    Morita, R.2    Bourdery, L.3    Bentebibel, S.E.4    Zurawski, S.M.5
  • 18
    • 84859711557 scopus 로고    scopus 로고
    • Functional STAT3 deficiency compromises the generation of human T follicular helper cells
    • Ma CS, Avery DT, Chan A, Batten M, Bustamante J, et al. (2012) Functional STAT3 deficiency compromises the generation of human T follicular helper cells. Blood 119: 3997-4008.
    • (2012) Blood , vol.119 , pp. 3997-4008
    • Ma, C.S.1    Avery, D.T.2    Chan, A.3    Batten, M.4    Bustamante, J.5
  • 19
    • 70350492504 scopus 로고    scopus 로고
    • New insights into the differentiation and function of T follicular helper cells
    • King C, (2009) New insights into the differentiation and function of T follicular helper cells. Nat Rev Immunol 9: 757-766.
    • (2009) Nat Rev Immunol , vol.9 , pp. 757-766
    • King, C.1
  • 20
    • 49649120932 scopus 로고    scopus 로고
    • IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4
    • Avery DT, Bryant VL, Ma CS, de Waal Malefyt R, Tangye SG, (2008) IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4. J Immunol 181: 1767-1779.
    • (2008) J Immunol , vol.181 , pp. 1767-1779
    • Avery, D.T.1    Bryant, V.L.2    Ma, C.S.3    de Waal Malefyt, R.4    Tangye, S.G.5
  • 21
    • 38049101408 scopus 로고    scopus 로고
    • Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells
    • Bryant VL, Ma CS, Avery DT, Li Y, Good KL, et al. (2007) Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells. J Immunol 179: 8180-8190.
    • (2007) J Immunol , vol.179 , pp. 8180-8190
    • Bryant, V.L.1    Ma, C.S.2    Avery, D.T.3    Li, Y.4    Good, K.L.5
  • 22
    • 33847342813 scopus 로고    scopus 로고
    • IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells
    • Ettinger R, Sims GP, Robbins R, Withers D, Fischer RT, et al. (2007) IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells. J Immunol 178: 2872-2882.
    • (2007) J Immunol , vol.178 , pp. 2872-2882
    • Ettinger, R.1    Sims, G.P.2    Robbins, R.3    Withers, D.4    Fischer, R.T.5
  • 23
    • 33749531054 scopus 로고    scopus 로고
    • Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21
    • Good KL, Bryant VL, Tangye SG, (2006) Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21. J Immunol 177: 5236-5247.
    • (2006) J Immunol , vol.177 , pp. 5236-5247
    • Good, K.L.1    Bryant, V.L.2    Tangye, S.G.3
  • 24
    • 10944228245 scopus 로고    scopus 로고
    • B cells alter the phenotype and function of follicular-homing CXCR5+ T cells
    • Ebert LM, Horn MP, Lang AB, Moser B, (2004) B cells alter the phenotype and function of follicular-homing CXCR5+ T cells. Eur J Immunol 34: 3562-3571.
    • (2004) Eur J Immunol , vol.34 , pp. 3562-3571
    • Ebert, L.M.1    Horn, M.P.2    Lang, A.B.3    Moser, B.4
  • 25
    • 15244363080 scopus 로고    scopus 로고
    • Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses
    • Lim HW, Hillsamer P, Kim CH, (2004) Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses. J Clin Invest 114: 1640-1649.
    • (2004) J Clin Invest , vol.114 , pp. 1640-1649
    • Lim, H.W.1    Hillsamer, P.2    Kim, C.H.3
  • 26
    • 23444434705 scopus 로고    scopus 로고
    • The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo
    • Akiba H, Takeda K, Kojima Y, Usui Y, Harada N, et al. (2005) The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo. J Immunol 175: 2340-2348.
    • (2005) J Immunol , vol.175 , pp. 2340-2348
    • Akiba, H.1    Takeda, K.2    Kojima, Y.3    Usui, Y.4    Harada, N.5
  • 27
    • 33749151018 scopus 로고    scopus 로고
    • ICOS deficiency is associated with a severe reduction of CXCR5+CD4 germinal center Th cells
    • Bossaller L, Burger J, Draeger R, Grimbacher B, Knoth R, et al. (2006) ICOS deficiency is associated with a severe reduction of CXCR5+CD4 germinal center Th cells. J Immunol 177: 4927-4932.
    • (2006) J Immunol , vol.177 , pp. 4927-4932
    • Bossaller, L.1    Burger, J.2    Draeger, R.3    Grimbacher, B.4    Knoth, R.5
  • 28
    • 79959328032 scopus 로고    scopus 로고
    • ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6
    • Choi YS, Kageyama R, Eto D, Escobar TC, Johnston RJ, et al. (2011) ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6. Immunity 34: 932-946.
    • (2011) Immunity , vol.34 , pp. 932-946
    • Choi, Y.S.1    Kageyama, R.2    Eto, D.3    Escobar, T.C.4    Johnston, R.J.5
  • 29
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4 T cells (TFH)
    • Crotty S, (2011) Follicular helper CD4 T cells (TFH). Annu Rev Immunol 29: 621-663.
    • (2011) Annu Rev Immunol , vol.29 , pp. 621-663
    • Crotty, S.1
  • 30
    • 69249109601 scopus 로고    scopus 로고
    • Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
    • Johnston RJ, Poholek AC, DiToro D, Yusuf I, Eto D, et al. (2009) Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science 325: 1006-1010.
    • (2009) Science , vol.325 , pp. 1006-1010
    • Johnston, R.J.1    Poholek, A.C.2    DiToro, D.3    Yusuf, I.4    Eto, D.5
  • 31
    • 69249101229 scopus 로고    scopus 로고
    • Bcl6 mediates the development of T follicular helper cells
    • Nurieva RI, Chung Y, Martinez GJ, Yang XO, Tanaka S, et al. (2009) Bcl6 mediates the development of T follicular helper cells. Science 325: 1001-1005.
    • (2009) Science , vol.325 , pp. 1001-1005
    • Nurieva, R.I.1    Chung, Y.2    Martinez, G.J.3    Yang, X.O.4    Tanaka, S.5
  • 32
    • 70049101558 scopus 로고    scopus 로고
    • The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment
    • Yu D, Rao S, Tsai LM, Lee SK, He Y, et al. (2009) The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity 31: 457-468.
    • (2009) Immunity , vol.31 , pp. 457-468
    • Yu, D.1    Rao, S.2    Tsai, L.M.3    Lee, S.K.4    He, Y.5
  • 33
    • 3242741987 scopus 로고    scopus 로고
    • ICOS expression by activated human Th cells is enhanced by IL-12 and IL-23: increased ICOS expression enhances the effector function of both Th1 and Th2 cells
    • Wassink L, Vieira PL, Smits HH, Kingsbury GA, Coyle AJ, et al. (2004) ICOS expression by activated human Th cells is enhanced by IL-12 and IL-23: increased ICOS expression enhances the effector function of both Th1 and Th2 cells. J Immunol 173: 1779-1786.
    • (2004) J Immunol , vol.173 , pp. 1779-1786
    • Wassink, L.1    Vieira, P.L.2    Smits, H.H.3    Kingsbury, G.A.4    Coyle, A.J.5
  • 34
    • 33845954438 scopus 로고    scopus 로고
    • Elevated activity of STAT3C due to higher DNA binding affinity of phosphotyrosine dimer rather than covalent dimer formation
    • Li L, Shaw PE, (2006) Elevated activity of STAT3C due to higher DNA binding affinity of phosphotyrosine dimer rather than covalent dimer formation. J Biol Chem 281: 33172-33181.
    • (2006) J Biol Chem , vol.281 , pp. 33172-33181
    • Li, L.1    Shaw, P.E.2
  • 37
    • 0025877075 scopus 로고
    • Antibody responses to protein, polysaccharide, and phi X174 antigens in the hyperimmunoglobulinemia E (hyper-IgE) syndrome
    • Sheerin KA, Buckley RH, (1991) Antibody responses to protein, polysaccharide, and phi X174 antigens in the hyperimmunoglobulinemia E (hyper-IgE) syndrome. J Allergy Clin Immunol 87: 803-811.
    • (1991) J Allergy Clin Immunol , vol.87 , pp. 803-811
    • Sheerin, K.A.1    Buckley, R.H.2
  • 38
    • 76149139419 scopus 로고    scopus 로고
    • B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans
    • Avery DT, Deenick EK, Ma CS, Suryani S, Simpson N, et al. (2010) B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans. J Exp Med 207: 155-171.
    • (2010) J Exp Med , vol.207 , pp. 155-171
    • Avery, D.T.1    Deenick, E.K.2    Ma, C.S.3    Suryani, S.4    Simpson, N.5
  • 40
    • 77954959530 scopus 로고    scopus 로고
    • Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression
    • Glasmacher E, Hoefig KP, Vogel KU, Rath N, Du L, et al. (2010) Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression. Nat Immunol 11: 725-733.
    • (2010) Nat Immunol , vol.11 , pp. 725-733
    • Glasmacher, E.1    Hoefig, K.P.2    Vogel, K.U.3    Rath, N.4    Du, L.5
  • 41
    • 21144438325 scopus 로고    scopus 로고
    • A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity
    • Vinuesa CG, Cook MC, Angelucci C, Athanasopoulos V, Rui L, et al. (2005) A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity. Nature 435: 452-458.
    • (2005) Nature , vol.435 , pp. 452-458
    • Vinuesa, C.G.1    Cook, M.C.2    Angelucci, C.3    Athanasopoulos, V.4    Rui, L.5
  • 42
    • 36048946330 scopus 로고    scopus 로고
    • Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA
    • Yu D, Tan AH, Hu X, Athanasopoulos V, Simpson N, et al. (2007) Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA. Nature 450: 299-303.
    • (2007) Nature , vol.450 , pp. 299-303
    • Yu, D.1    Tan, A.H.2    Hu, X.3    Athanasopoulos, V.4    Simpson, N.5
  • 43
    • 33749382321 scopus 로고    scopus 로고
    • Regulation of mouse inducible costimulator (ICOS) expression by Fyn-NFATc2 and ERK signaling in T cells
    • Tan AH, Wong SC, Lam KP, (2006) Regulation of mouse inducible costimulator (ICOS) expression by Fyn-NFATc2 and ERK signaling in T cells. J Biol Chem 281: 28666-28678.
    • (2006) J Biol Chem , vol.281 , pp. 28666-28678
    • Tan, A.H.1    Wong, S.C.2    Lam, K.P.3
  • 44
    • 80052945186 scopus 로고    scopus 로고
    • Oncogenic tyrosine kinase NPM-ALK induces expression of the growth-promoting receptor ICOS
    • Zhang Q, Wang H, Kantekure K, Paterson JC, Liu X, et al. (2011) Oncogenic tyrosine kinase NPM-ALK induces expression of the growth-promoting receptor ICOS. Blood 118: 3062-3071.
    • (2011) Blood , vol.118 , pp. 3062-3071
    • Zhang, Q.1    Wang, H.2    Kantekure, K.3    Paterson, J.C.4    Liu, X.5


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