-
1
-
-
24644441655
-
The role of radiotherapy in cancer treatment: Estimating optimal utilization from a review of evidence-based clinical guidelines
-
Delaney, G.; Jacob, S.; Featherstone, C.; Barton, M. The role of radiotherapy in cancer treatment: Estimating optimal utilization from a review of evidence-based clinical guidelines. Cancer 2005, 104, 1129-1137.
-
(2005)
Cancer
, vol.104
, pp. 1129-1137
-
-
Delaney, G.1
Jacob, S.2
Featherstone, C.3
Barton, M.4
-
3
-
-
34248149008
-
Palliative radiotherapy trials for bone metastases: A systematic review
-
Chow, E.; Harris, K.; Fan, G.; Tsao, M.; Sze, W.M. Palliative radiotherapy trials for bone metastases: A systematic review. J. Clin. Oncol. 2007, 25, 1423-1436.
-
(2007)
J. Clin. Oncol
, vol.25
, pp. 1423-1436
-
-
Chow, E.1
Harris, K.2
Fan, G.3
Tsao, M.4
Sze, W.M.5
-
4
-
-
33847640529
-
Exploitable mechanisms for combining drugs with radiation: Concepts, achievements and future directions
-
Bentzen, S.M.; Harari, P.M.; Bernier, J. Exploitable mechanisms for combining drugs with radiation: Concepts, achievements and future directions. Nat. Clin. Pract. Oncol. 2007, 4, 172-180.
-
(2007)
Nat. Clin. Pract. Oncol
, vol.4
, pp. 172-180
-
-
Bentzen, S.M.1
Harari, P.M.2
Bernier, J.3
-
6
-
-
84872003539
-
NCI-RTOG translational program strategic guidelines for the early-stage development of radiosensitizers
-
Lawrence, Y.R.; Vikram, B.; Dignam, J.J.; Chakravarti, A.; Machtay, M.; Freidlin, B.; Takebe, N.; Curran, W.J.; Bentzen, S.M.; Okunieff, P., et al. NCI-RTOG translational program strategic guidelines for the early-stage development of radiosensitizers. J. Natl. Cancer Inst. 2013, 105, 11-24.
-
(2013)
J. Natl. Cancer Inst
, vol.105
, pp. 11-24
-
-
Lawrence, Y.R.1
Vikram, B.2
Dignam, J.J.3
Chakravarti, A.4
Machtay, M.5
Freidlin, B.6
Takebe, N.7
Curran, W.J.8
Bentzen, S.M.9
Okunieff, P.10
-
7
-
-
34548145838
-
Molecular biology for the radiation oncologist: The 5Rs of radiobiology meet the hallmarks of cancer
-
Harrington, K.; Jankowska, P.; Hingorani, M. Molecular biology for the radiation oncologist: The 5Rs of radiobiology meet the hallmarks of cancer. Clin. Oncol. 2007, 19, 561-571.
-
(2007)
Clin. Oncol
, vol.19
, pp. 561-571
-
-
Harrington, K.1
Jankowska, P.2
Hingorani, M.3
-
8
-
-
0031909654
-
A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85
-
Overgaard, J.; Hansen, H.S.; Overgaard, M.; Bastholt, L.; Berthelsen, A.; Specht, L.; Lindeløv, B.; Jørgensen, K. A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85. Radiother. Oncol. 1998, 46, 135-146.
-
(1998)
Radiother. Oncol
, vol.46
, pp. 135-146
-
-
Overgaard, J.1
Hansen, H.S.2
Overgaard, M.3
Bastholt, L.4
Berthelsen, A.5
Specht, L.6
Lindeløv, B.7
Jørgensen, K.8
-
9
-
-
34748860952
-
Hypoxic radiosensitization: Adored and ignored
-
Overgaard, J. Hypoxic radiosensitization: Adored and ignored. J. Clin. Oncol. 2007, 25, 4066-4074.
-
(2007)
J. Clin. Oncol
, vol.25
, pp. 4066-4074
-
-
Overgaard, J.1
-
10
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Bonner, J.A.; Harari, P.M.; Giralt, J.; Azarnia, N.; Shin, D.M.; Cohen, R.B.; Jones, C.U.; Sur, R.; Raben, D.; Jassem, J., et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N. Engl. J. Med. 2006, 354, 567-578.
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
Azarnia, N.4
Shin, D.M.5
Cohen, R.B.6
Jones, C.U.7
Sur, R.8
Raben, D.9
Jassem, J.10
-
11
-
-
80052023514
-
Guidelines for preclinical and early phase clinical assessment of novel radiosensitisers
-
Harrington, K.J.; Billingham, L.J.; Brunner, T.B.; Burnet, N.G.; Chan, C.S.; Hoskin, P.; Mackay, R.I.; Maughan, T.S.; Macdougall, J.; McKenna, W.G., et al. Guidelines for preclinical and early phase clinical assessment of novel radiosensitisers. Br. J. Cancer 2011, 105, 628-639.
-
(2011)
Br. J. Cancer
, vol.105
, pp. 628-639
-
-
Harrington, K.J.1
Billingham, L.J.2
Brunner, T.B.3
Burnet, N.G.4
Chan, C.S.5
Hoskin, P.6
Mackay, R.I.7
Maughan, T.S.8
Macdougall, J.9
McKenna, W.G.10
-
12
-
-
84880709879
-
Toxicity of Phase I Radiation Oncology Trials: Worldwide Experience
-
Journal, B.; Glass, C. Toxicity of Phase I Radiation Oncology Trials: Worldwide Experience. Bodine J. 2010, 3, 1-2.
-
(2010)
Bodine J
, vol.3
, pp. 1-2
-
-
Journal, B.1
Glass, C.2
-
13
-
-
84872044020
-
The clinical development of molecularly targeted agents in combination with radiation therapy: A pharmaceutical perspective
-
Ataman, O.U.; Sambrook, S.J.; Wilks, C.; Lloyd, A.; Taylor, A.E.; Wedge, S.R. The clinical development of molecularly targeted agents in combination with radiation therapy: A pharmaceutical perspective. Int. J. Radiat. Oncol. Biol. Phys. 2012, 84, e447-454.
-
(2012)
Int. J. Radiat. Oncol. Biol. Phys
, vol.84
-
-
Ataman, O.U.1
Sambrook, S.J.2
Wilks, C.3
Lloyd, A.4
Taylor, A.E.5
Wedge, S.R.6
-
14
-
-
84877992706
-
Opportunities and challenges in the era of molecularly targeted agents and radiation therapy
-
Lin, S.H.; George, T.J.; Ben-Josef, E.; Bradley, J.; Choe, K.S.; Edelman, M.J.; Guha, C.; Krishnan, S.; Lawrence, T.S.; Le, Q.-T., et al. Opportunities and challenges in the era of molecularly targeted agents and radiation therapy. J. Natl. Cancer Inst. 2013, 105, 686-693.
-
(2013)
J. Natl. Cancer Inst
, vol.105
, pp. 686-693
-
-
Lin, S.H.1
George, T.J.2
Ben-Josef, E.3
Bradley, J.4
Choe, K.S.5
Edelman, M.J.6
Guha, C.7
Krishnan, S.8
Lawrence, T.S.9
Le, Q.-T.10
-
15
-
-
0038363472
-
Development of investigational radiation modifiers
-
Colevas, A.D.; Brown, J.M.; Hahn, S.; Mitchell, J.; Camphausen, K.; Coleman, C.N. Development of investigational radiation modifiers. J. Natl. Cancer Inst. 2003, 95, 646-651.
-
(2003)
J. Natl. Cancer Inst
, vol.95
, pp. 646-651
-
-
Colevas, A.D.1
Brown, J.M.2
Hahn, S.3
Mitchell, J.4
Camphausen, K.5
Coleman, C.N.6
-
16
-
-
0019986528
-
The enhanced sensitivity of mammalian cells to killing by X rays after prolonged exposure to several nitroimidazoles
-
Hall, E.J.; Astor, M.; Biaglow, J.; Parham, J.C. The enhanced sensitivity of mammalian cells to killing by X rays after prolonged exposure to several nitroimidazoles. Int. J. Radiat. Oncol. Biol. Phys. 1982, 8, 447-451.
-
(1982)
Int. J. Radiat. Oncol. Biol. Phys
, vol.8
, pp. 447-451
-
-
Hall, E.J.1
Astor, M.2
Biaglow, J.3
Parham, J.C.4
-
17
-
-
34548713013
-
Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical library
-
Lally, B.E.; Geiger, G.A.; Kridel, S.; Arcury-Quandt, A.E.; Robbins, M.E.; Kock, N.D.; Wheeler, K.; Peddi, P.; Georgakilas, A.; Kao, G.D., et al. Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical library. Cancer Res. 2007, 67, 8791-8799.
-
(2007)
Cancer Res
, vol.67
, pp. 8791-8799
-
-
Lally, B.E.1
Geiger, G.A.2
Kridel, S.3
Arcury-Quandt, A.E.4
Robbins, M.E.5
Kock, N.D.6
Wheeler, K.7
Peddi, P.8
Georgakilas, A.9
Kao, G.D.10
-
18
-
-
34548313955
-
Clonogenic assay of cells in vitro
-
Franken, N.A.P.; Rodermond, H.M.; Stap, J.; Haveman, J.; Van Bree, C. Clonogenic assay of cells in vitro. Nat. Protoc. 2006, 1, 2315-2319.
-
(2006)
Nat. Protoc
, vol.1
, pp. 2315-2319
-
-
Franken, N.A.P.1
Rodermond, H.M.2
Stap, J.3
Haveman, J.4
van Bree, C.5
-
19
-
-
76549129820
-
Drug combination studies and their synergy quantification using the Chou-Talalay method
-
Chou, T.-C. Drug combination studies and their synergy quantification using the Chou-Talalay method. Cancer Res. 2010, 70, 440-446.
-
(2010)
Cancer Res
, vol.70
, pp. 440-446
-
-
Chou, T.-C.1
-
20
-
-
0021118703
-
Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
-
Chou, T.C.; Talalay, P. Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regul. 1984, 22, 27-55.
-
(1984)
Adv. Enzyme Regul
, vol.22
, pp. 27-55
-
-
Chou, T.C.1
Talalay, P.2
-
21
-
-
38949175427
-
Enhanced in vitro and in vivo cytotoxicity of combined reovirus and radiotherapy
-
Twigger, K.; Vidal, L.; White, C.L.; de Bono, J.S.; Bhide, S.; Coffey, M.; Thompson, B.; Vile, R.G.; Heinemann, L.; Pandha, H.S., et al. Enhanced in vitro and in vivo cytotoxicity of combined reovirus and radiotherapy. Clin. Cancer Res. 2008, 14, 912-923.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 912-923
-
-
Twigger, K.1
Vidal, L.2
White, C.L.3
de Bono, J.S.4
Bhide, S.5
Coffey, M.6
Thompson, B.7
Vile, R.G.8
Heinemann, L.9
Pandha, H.S.10
-
22
-
-
84863651484
-
Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis
-
doi:10.1371/journal.pgen.1002650
-
Tran, P.T.; Shroff, E.H.; Burns, T.F.; Thiyagarajan, S.; Das, S.T.; Zabuawala, T.; Chen, J.; Cho, Y.-J.; Luong, R.; Tamayo, P., et al. Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis. PLoS Genet. 2012, 8, doi:10.1371/journal.pgen.1002650.
-
(2012)
PLoS Genet
, vol.8
-
-
Tran, P.T.1
Shroff, E.H.2
Burns, T.F.3
Thiyagarajan, S.4
Das, S.T.5
Zabuawala, T.6
Chen, J.7
Cho, Y.-J.8
Luong, R.9
Tamayo, P.10
-
23
-
-
84877785851
-
Animal models of human prostate cancer: The consensus report of the New York meeting of the mouse models of human cancers consortium prostate pathology committee
-
Ittmann, M.; Huang, J.; Radaelli, E.; Martin, P.; Signoretti, S.; Sullivan, R.; Simons, B.W.; Ward, J.M.; Robinson, B.D.; Chu, G.C., et al. Animal models of human prostate cancer: The consensus report of the New York meeting of the mouse models of human cancers consortium prostate pathology committee. Cancer Res. 2013, 73, 2718-2736.
-
(2013)
Cancer Res
, vol.73
, pp. 2718-2736
-
-
Ittmann, M.1
Huang, J.2
Radaelli, E.3
Martin, P.4
Signoretti, S.5
Sullivan, R.6
Simons, B.W.7
Ward, J.M.8
Robinson, B.D.9
Chu, G.C.10
-
24
-
-
47149101666
-
High-resolution, small animal radiation research platform with X-ray tomographic guidance capabilities
-
Wong, J.; Armour, E.; Kazanzides, P.; Iordachita, I.; Tryggestad, E.; Deng, H.; Matinfar, M.; Kennedy, C.; Liu, Z.; Chan, T., et al. High-resolution, small animal radiation research platform with X-ray tomographic guidance capabilities. Int. J. Radiat. Oncol. Biol. Phys. 2008, 71, 1591-1599.
-
(2008)
Int. J. Radiat. Oncol. Biol. Phys
, vol.71
, pp. 1591-1599
-
-
Wong, J.1
Armour, E.2
Kazanzides, P.3
Iordachita, I.4
Tryggestad, E.5
Deng, H.6
Matinfar, M.7
Kennedy, C.8
Liu, Z.9
Chan, T.10
-
25
-
-
36649037794
-
MicroRT-small animal conformal irradiator
-
Stojadinovic, S.; Low, D.A.; Hope, A.J.; Vicic, M.; Deasy, J.O.; Cui, J.; Khullar, D.; Parikh, P.J.; Malinowski, K.T.; Izaguirre, E.W., et al. MicroRT-small animal conformal irradiator. Med. Phys. 2007, 34, 4706-4716.
-
(2007)
Med. Phys
, vol.34
, pp. 4706-4716
-
-
Stojadinovic, S.1
Low, D.A.2
Hope, A.J.3
Vicic, M.4
Deasy, J.O.5
Cui, J.6
Khullar, D.7
Parikh, P.J.8
Malinowski, K.T.9
Izaguirre, E.W.10
-
26
-
-
0014723302
-
Microcolony survival assay for cells of mouse intestinal mucosa exposed to radiation
-
Withers, H.R.; Elkind, M.M. Microcolony survival assay for cells of mouse intestinal mucosa exposed to radiation. Int. J. Radiat. Biol. 1970, 17, 261-267.
-
(1970)
Int. J. Radiat. Biol
, vol.17
, pp. 261-267
-
-
Withers, H.R.1
Elkind, M.M.2
-
27
-
-
0025848358
-
Proliferation kinetics of mouse tongue epithelium under normal conditions and following single dose irradiation
-
Dörr, W.; Kummermehr, J. Proliferation kinetics of mouse tongue epithelium under normal conditions and following single dose irradiation. Virchows Arch. B 1991, 60, 287-294.
-
(1991)
Virchows Arch. B
, vol.60
, pp. 287-294
-
-
Dörr, W.1
Kummermehr, J.2
-
28
-
-
34249320540
-
Effects of prolongation of overall treatment time due to unplanned interruptions during radiotherapy of different tumor sites and practical methods for compensation
-
Bese, N.S.; Hendry, J.; Jeremic, B. Effects of prolongation of overall treatment time due to unplanned interruptions during radiotherapy of different tumor sites and practical methods for compensation. Int. J. Radiat. Oncol. Biol. Phys. 2007, 68, 654-661.
-
(2007)
Int. J. Radiat. Oncol. Biol. Phys
, vol.68
, pp. 654-661
-
-
Bese, N.S.1
Hendry, J.2
Jeremic, B.3
-
29
-
-
84862525933
-
Tissue biomarkers for prostate cancer radiation therapy
-
Tran, P.T.; Hales, R.K.; Zeng, J.; Aziz, K.; Salih, T.; Gajula, R.P.; Chettiar, S.; Gandhi, N.; Wild, A.T.; Kumar, R., et al. Tissue biomarkers for prostate cancer radiation therapy. Curr. Mol. Med. 2012, 12, 772-787.
-
(2012)
Curr. Mol. Med
, vol.12
, pp. 772-787
-
-
Tran, P.T.1
Hales, R.K.2
Zeng, J.3
Aziz, K.4
Salih, T.5
Gajula, R.P.6
Chettiar, S.7
Gandhi, N.8
Wild, A.T.9
Kumar, R.10
-
30
-
-
0032188742
-
Prostate-specific membrane antigen expression is greatest in prostate adenocarcinoma and lymph node metastases
-
Sweat, S.D.; Pacelli, A.; Murphy, G.P.; Bostwick, D.G. Prostate-specific membrane antigen expression is greatest in prostate adenocarcinoma and lymph node metastases. Urology 1998, 52, 637-640.
-
(1998)
Urology
, vol.52
, pp. 637-640
-
-
Sweat, S.D.1
Pacelli, A.2
Murphy, G.P.3
Bostwick, D.G.4
-
31
-
-
0030219893
-
Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy
-
Wright, G.L.; Grob, B.M.; Haley, C.; Grossman, K.; Newhall, K.; Petrylak, D.; Troyer, J.; Konchuba, A.; Schellhammer, P.F.; Moriarty, R. Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy. Urology 1996, 48, 326-334.
-
(1996)
Urology
, vol.48
, pp. 326-334
-
-
Wright, G.L.1
Grob, B.M.2
Haley, C.3
Grossman, K.4
Newhall, K.5
Petrylak, D.6
Troyer, J.7
Konchuba, A.8
Schellhammer, P.F.9
Moriarty, R.10
-
32
-
-
0346333234
-
Correlation of primary tumor prostate-specific membrane antigen expression with disease recurrence in prostate cancer
-
Ross, J.S.; Sheehan, C.E.; Fisher, H.A.G.; Kaufman, R.P.; Kaur, P.; Gray, K.; Webb, I.; Gray, G.S.; Mosher, R.; Kallakury, B.V.S. Correlation of primary tumor prostate-specific membrane antigen expression with disease recurrence in prostate cancer. Clin. Cancer Res. 2003, 9, 6357-6362.
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 6357-6362
-
-
Ross, J.S.1
Sheehan, C.E.2
Fisher, H.A.G.3
Kaufman, R.P.4
Kaur, P.5
Gray, K.6
Webb, I.7
Gray, G.S.8
Mosher, R.9
Kallakury, B.V.S.10
-
33
-
-
79959328548
-
Noninvasive measurement of androgen receptor signaling with a positron-emitting radiopharmaceutical that targets prostate-specific membrane antigen
-
Evans, M.J.; Smith-Jones, P.M.; Wongvipat, J.; Navarro, V.; Kim, S.; Bander, N.H.; Larson, S.M.; Sawyers, C.L. Noninvasive measurement of androgen receptor signaling with a positron-emitting radiopharmaceutical that targets prostate-specific membrane antigen. Proc. Natl. Acad. Sci. USA 2011, 108, 9578-9582.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 9578-9582
-
-
Evans, M.J.1
Smith-Jones, P.M.2
Wongvipat, J.3
Navarro, V.4
Kim, S.5
Bander, N.H.6
Larson, S.M.7
Sawyers, C.L.8
-
34
-
-
28144449723
-
The progress and promise of molecular imaging probes in oncologic drug development
-
Kelloff, G.J.; Krohn, K.A.; Larson, S.M.; Weissleder, R.; Mankoff, D.A.; Hoffman, J.M.; Link, J.M.; Guyton, K.Z.; Eckelman, W.C.; Scher, H.I., et al. The progress and promise of molecular imaging probes in oncologic drug development. Clin. Cancer Res. 2005, 11, 7967-7985.
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 7967-7985
-
-
Kelloff, G.J.1
Krohn, K.A.2
Larson, S.M.3
Weissleder, R.4
Mankoff, D.A.5
Hoffman, J.M.6
Link, J.M.7
Guyton, K.Z.8
Eckelman, W.C.9
Scher, H.I.10
-
35
-
-
33746036112
-
Consensus recommendations for the use of 18F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute Trials
-
Shankar, L.K.; Hoffman, J.M.; Bacharach, S.; Graham, M.M.; Karp, J.; Lammertsma, A.A.; Larson, S.; Mankoff, D.A.; Siegel, B.A.; van den Abbeele, A., et al. Consensus recommendations for the use of 18F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute Trials. J. Nucl. Med. 2006, 47, 1059-1066.
-
(2006)
J. Nucl. Med
, vol.47
, pp. 1059-1066
-
-
Shankar, L.K.1
Hoffman, J.M.2
Bacharach, S.3
Graham, M.M.4
Karp, J.5
Lammertsma, A.A.6
Larson, S.7
Mankoff, D.A.8
Siegel, B.A.9
van den, A.A.10
-
36
-
-
0035722652
-
Local detection of prostate cancer by positron emission tomography with 2-fluorodeoxyglucose: Comparison of filtered back projection and iterative reconstruction with segmented attenuation correction
-
Turlakow, A.; Larson, S.M.; Coakley, F.; Akhurst, T.; Gonen, M.; Macapinlac, H.A.; Kelly, W.; Leibel, S.; Humm, J.; Scardino, P., et al. Local detection of prostate cancer by positron emission tomography with 2-fluorodeoxyglucose: Comparison of filtered back projection and iterative reconstruction with segmented attenuation correction. Q. J. Nucl. Med. 2001, 45, 235-244.
-
(2001)
Q. J. Nucl. Med
, vol.45
, pp. 235-244
-
-
Turlakow, A.1
Larson, S.M.2
Coakley, F.3
Akhurst, T.4
Gonen, M.5
Macapinlac, H.A.6
Kelly, W.7
Leibel, S.8
Humm, J.9
Scardino, P.10
-
37
-
-
0032993484
-
Fluorine-18-fluorodeoxyglucose positron emission tomography is useless for the detection of local recurrence after radical prostatectomy
-
Hofer, C.; Laubenbacher, C.; Block, T.; Breul, J.; Hartung, R.; Schwaiger, M. Fluorine-18-fluorodeoxyglucose positron emission tomography is useless for the detection of local recurrence after radical prostatectomy. Eur. Urol. 1999, 36, 31-35.
-
(1999)
Eur. Urol
, vol.36
, pp. 31-35
-
-
Hofer, C.1
Laubenbacher, C.2
Block, T.3
Breul, J.4
Hartung, R.5
Schwaiger, M.6
-
38
-
-
0036007407
-
Combined 18F-FDG and 11C-methionine PET scans in patients with newly progressive metastatic prostate cancer
-
Nuñez, R.; Macapinlac, H.A.; Yeung, H.W.D.; Akhurst, T.; Cai, S.; Osman, I.; Gonen, M.; Riedel, E.; Scher, H.I.; Larson, S.M. Combined 18F-FDG and 11C-methionine PET scans in patients with newly progressive metastatic prostate cancer. J. Nucl. Med. 2002, 43, 46-55.
-
(2002)
J. Nucl. Med
, vol.43
, pp. 46-55
-
-
Nuñez, R.1
Macapinlac, H.A.2
Yeung, H.W.D.3
Akhurst, T.4
Cai, S.5
Osman, I.6
Gonen, M.7
Riedel, E.8
Scher, H.I.9
Larson, S.M.10
-
39
-
-
0029888387
-
Metastatic prostate cancer: Initial findings of PET with 2-deoxy-2-[F-18]fluoro-D-glucose
-
Shreve, P.D.; Grossman, H.B.; Gross, M.D.; Wahl, R.L. Metastatic prostate cancer: Initial findings of PET with 2-deoxy-2-[F-18]fluoro-D-glucose. Radiology 1996, 199, 751-756.
-
(1996)
Radiology
, vol.199
, pp. 751-756
-
-
Shreve, P.D.1
Grossman, H.B.2
Gross, M.D.3
Wahl, R.L.4
-
40
-
-
34147215441
-
Imaging prostate cancer: A multidisciplinary perspective
-
Hricak, H.; Choyke, P.L.; Eberhardt, S.C.; Leibel, S.A.; Scardino, P.T. Imaging prostate cancer: A multidisciplinary perspective. Radiology 2007, 243, 28-53.
-
(2007)
Radiology
, vol.243
, pp. 28-53
-
-
Hricak, H.1
Choyke, P.L.2
Eberhardt, S.C.3
Leibel, S.A.4
Scardino, P.T.5
-
41
-
-
33645731918
-
Positron emission tomography and molecular imaging of the prostate: An update
-
Lawrentschuk, N.; Davis, I.D.; Bolton, D.M.; Scott, A.M. Positron emission tomography and molecular imaging of the prostate: An update. BJU Int. 2006, 97, 923-931.
-
(2006)
BJU Int
, vol.97
, pp. 923-931
-
-
Lawrentschuk, N.1
Davis, I.D.2
Bolton, D.M.3
Scott, A.M.4
-
42
-
-
34250741978
-
Detection of lymph-node metastases with integrated [11C]choline PET/CT in patients with PSA failure after radical retropubic prostatectomy: Results confirmed by open pelvic-retroperitoneal lymphadenectomy
-
Scattoni, V.; Picchio, M.; Suardi, N.; Messa, C.; Freschi, M.; Roscigno, M.; da Pozzo, L.; Bocciardi, A.; Rigatti, P.; Fazio, F. Detection of lymph-node metastases with integrated [11C]choline PET/CT in patients with PSA failure after radical retropubic prostatectomy: Results confirmed by open pelvic-retroperitoneal lymphadenectomy. Eur. Urol. 2007, 52, 423-429.
-
(2007)
Eur. Urol
, vol.52
, pp. 423-429
-
-
Scattoni, V.1
Picchio, M.2
Suardi, N.3
Messa, C.4
Freschi, M.5
Roscigno, M.6
da Pozzo, L.7
Bocciardi, A.8
Rigatti, P.9
Fazio, F.10
-
43
-
-
0037363313
-
Preoperative staging of pelvic lymph nodes in prostate cancer by 11C-choline PET
-
De Jong, I.J.; Pruim, J.; Elsinga, P.H.; Vaalburg, W.; Mensink, H.J. Preoperative staging of pelvic lymph nodes in prostate cancer by 11C-choline PET. J. Nucl. Med. 2003, 44, 331-335.
-
(2003)
J. Nucl. Med
, vol.44
, pp. 331-335
-
-
de Jong, I.J.1
Pruim, J.2
Elsinga, P.H.3
Vaalburg, W.4
Mensink, H.J.5
-
44
-
-
0037374728
-
Value of [11C]choline-positron emission tomography for re-staging prostate cancer: A comparison with [18F]fluorodeoxyglucose-positron emission tomography
-
Picchio, M.; Messa, C.; Landoni, C.; Gianolli, L.; Sironi, S.; Brioschi, M.; Matarrese, M.; Matei, D.V.; de Cobelli, F.; del Maschio, A., et al. Value of [11C]choline-positron emission tomography for re-staging prostate cancer: A comparison with [18F]fluorodeoxyglucose-positron emission tomography. J. Urol. 2003, 169, 1337-1340.
-
(2003)
J. Urol
, vol.169
, pp. 1337-1340
-
-
Picchio, M.1
Messa, C.2
Landoni, C.3
Gianolli, L.4
Sironi, S.5
Brioschi, M.6
Matarrese, M.7
Matei, D.V.8
de Cobelli, F.9
del, M.A.10
-
46
-
-
33746187320
-
The detection of bone metastases in patients with high-risk prostate cancer: 99mTc-MDP Planar bone scintigraphy, single- and multi-field-of-view SPECT, 18F-fluoride PET, and 18F-fluoride PET/CT
-
Even-Sapir, E.; Metser, U.; Mishani, E.; Lievshitz, G.; Lerman, H.; Leibovitch, I. The detection of bone metastases in patients with high-risk prostate cancer: 99mTc-MDP Planar bone scintigraphy, single- and multi-field-of-view SPECT, 18F-fluoride PET, and 18F-fluoride PET/CT. J. Nucl. Med. 2006, 47, 287-297.
-
(2006)
J. Nucl. Med
, vol.47
, pp. 287-297
-
-
Even-Sapir, E.1
Metser, U.2
Mishani, E.3
Lievshitz, G.4
Lerman, H.5
Leibovitch, I.6
-
47
-
-
34848895720
-
18F-Fluoride positron emission tomography and positron emission tomography/computed tomography
-
Even-Sapir, E.; Mishani, E.; Flusser, G.; Metser, U. 18F-Fluoride positron emission tomography and positron emission tomography/computed tomography. Semin. Nucl. Med. 2007, 37, 462-469.
-
(2007)
Semin. Nucl. Med
, vol.37
, pp. 462-469
-
-
Even-Sapir, E.1
Mishani, E.2
Flusser, G.3
Metser, U.4
-
48
-
-
75749116783
-
Pharmacokinetic assessment of the uptake of 16beta-18F-fluoro-5alpha-dihydrotestosterone (FDHT) in prostate tumors as measured by PET
-
Beattie, B.J.; Smith-Jones, P.M.; Jhanwar, Y.S.; Schöder, H.; Schmidtlein, C.R.; Morris, M.J.; Zanzonico, P.; Squire, O.; Meirelles, G.S.P.; Finn, R., et al. Pharmacokinetic assessment of the uptake of 16beta-18F-fluoro-5alpha-dihydrotestosterone (FDHT) in prostate tumors as measured by PET. J. Nucl. Med. 2010, 51, 183-192.
-
(2010)
J. Nucl. Med
, vol.51
, pp. 183-192
-
-
Beattie, B.J.1
Smith-Jones, P.M.2
Jhanwar, Y.S.3
Schöder, H.4
Schmidtlein, C.R.5
Morris, M.J.6
Zanzonico, P.7
Squire, O.8
Meirelles, G.S.P.9
Finn, R.10
-
49
-
-
79956327484
-
Detection of recurrent prostate carcinoma with anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid PET/CT and 111In-capromab pendetide SPECT/CT
-
Schuster, D.M.; Savir-Baruch, B.; Nieh, P.T.; Master, V.A.; Halkar, R.K.; Rossi, P.J.; Lewis, M.M.; Nye, J.A.; Yu, W.; Bowman, F.D., et al. Detection of recurrent prostate carcinoma with anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid PET/CT and 111In-capromab pendetide SPECT/CT. Radiology 2011, 259, 852-861.
-
(2011)
Radiology
, vol.259
, pp. 852-861
-
-
Schuster, D.M.1
Savir-Baruch, B.2
Nieh, P.T.3
Master, V.A.4
Halkar, R.K.5
Rossi, P.J.6
Lewis, M.M.7
Nye, J.A.8
Yu, W.9
Bowman, F.D.10
-
50
-
-
33847291423
-
Initial experience with the radiotracer anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid with PET/CT in prostate carcinoma
-
Schuster, D.M.; Votaw, J.R.; Nieh, P.T.; Yu, W.; Nye, J.A.; Master, V.; Bowman, F.D.; Issa, M.M.; Goodman, M.M. Initial experience with the radiotracer anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid with PET/CT in prostate carcinoma. J. Nucl. Med. 2007, 48, 56-63.
-
(2007)
J. Nucl. Med
, vol.48
, pp. 56-63
-
-
Schuster, D.M.1
Votaw, J.R.2
Nieh, P.T.3
Yu, W.4
Nye, J.A.5
Master, V.6
Bowman, F.D.7
Issa, M.M.8
Goodman, M.M.9
-
51
-
-
43549119285
-
Is there a role for positron emission tomography imaging in the early evaluation of prostate cancer relapse?
-
Greco, C.; Cascini, G.L.; Tamburrini, O. Is there a role for positron emission tomography imaging in the early evaluation of prostate cancer relapse? Prostate Cancer Prostatic Dis. 2008, 11, 121-128.
-
(2008)
Prostate Cancer Prostatic Dis
, vol.11
, pp. 121-128
-
-
Greco, C.1
Cascini, G.L.2
Tamburrini, O.3
-
52
-
-
0032104284
-
Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocarcinoma: A study of 184 cases
-
Bostwick, D.G.; Pacelli, A.; Blute, M.; Roche, P.; Murphy, G.P. Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocarcinoma: A study of 184 cases. Cancer 1998, 82, 2256-2261.
-
(1998)
Cancer
, vol.82
, pp. 2256-2261
-
-
Bostwick, D.G.1
Pacelli, A.2
Blute, M.3
Roche, P.4
Murphy, G.P.5
-
53
-
-
0035008378
-
Comparison of anti-prostate-specific membrane antigen antibodies and other immunomarkers in metastatic prostate carcinoma
-
Chang, S.S.; Reuter, V.E.; Heston, W.D.; Gaudin, P.B. Comparison of anti-prostate-specific membrane antigen antibodies and other immunomarkers in metastatic prostate carcinoma. Urology 2001, 57, 1179-1183.
-
(2001)
Urology
, vol.57
, pp. 1179-1183
-
-
Chang, S.S.1
Reuter, V.E.2
Heston, W.D.3
Gaudin, P.B.4
-
54
-
-
34147131288
-
Prostate-specific membrane antigen expression as a predictor of prostate cancer progression
-
Perner, S.; Hofer, M.D.; Kim, R.; Shah, R.B.; Li, H.; Möller, P.; Hautmann, R.E.; Gschwend, J.E.; Kuefer, R.; Rubin, M.A. Prostate-specific membrane antigen expression as a predictor of prostate cancer progression. Hum. Pathol. 2007, 38, 696-701.
-
(2007)
Hum. Pathol
, vol.38
, pp. 696-701
-
-
Perner, S.1
Hofer, M.D.2
Kim, R.3
Shah, R.B.4
Li, H.5
Möller, P.6
Hautmann, R.E.7
Gschwend, J.E.8
Kuefer, R.9
Rubin, M.A.10
-
55
-
-
84857431407
-
Principles and applications of diffusion-weighted imaging in cancer detection, staging, and treatment follow-up
-
Malayeri, A.A.; El Khouli, R.H.; Zaheer, A.; Jacobs, M.A.; Corona-Villalobos, C.P.; Kamel, I.R.; Macura, K.J. Principles and applications of diffusion-weighted imaging in cancer detection, staging, and treatment follow-up. Radiographics 2011, 31, 1773-1791.
-
(2011)
Radiographics
, vol.31
, pp. 1773-1791
-
-
Malayeri, A.A.1
El, K.R.H.2
Zaheer, A.3
Jacobs, M.A.4
Corona-Villalobos, C.P.5
Kamel, I.R.6
Macura, K.J.7
-
56
-
-
0037797284
-
Indium-111-capromab pendetide radioimmunoscintigraphy and prognosis for durable biochemical response to salvage radiation therapy in men after failed prostatectomy
-
Thomas, C.T.; Bradshaw, P.T.; Pollock, B.H.; Montie, J.E.; Taylor, J.M.G.; Thames, H.D.; McLaughlin, P.W.; DeBiose, D.A.; Hussey, D.H.; Wahl, R.L. Indium-111-capromab pendetide radioimmunoscintigraphy and prognosis for durable biochemical response to salvage radiation therapy in men after failed prostatectomy. J. Clin. Oncol. 2003, 21, 1715-1721.
-
(2003)
J. Clin. Oncol
, vol.21
, pp. 1715-1721
-
-
Thomas, C.T.1
Bradshaw, P.T.2
Pollock, B.H.3
Montie, J.E.4
Taylor, J.M.G.5
Thames, H.D.6
McLaughlin, P.W.7
Debiose, D.A.8
Hussey, D.H.9
Wahl, R.L.10
-
57
-
-
3242760707
-
The role of 111indium-capromab pendetide imaging for assessing biochemical failure after radical prostatectomy
-
Wilkinson, S.; Chodak, G. The role of 111indium-capromab pendetide imaging for assessing biochemical failure after radical prostatectomy. J. Urol. 2004, 172, 133-136.
-
(2004)
J. Urol
, vol.172
, pp. 133-136
-
-
Wilkinson, S.1
Chodak, G.2
-
58
-
-
84055217846
-
2-(3-{1-Carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid, [18F]DCFPyL, a PSMA-based PET imaging agent for prostate cancer
-
Chen, Y.; Pullambhatla, M.; Foss, C.A.; Byun, Y.; Nimmagadda, S.; Senthamizhchelvan, S.; Sgouros, G.; Mease, R.C.; Pomper, M.G. 2-(3-{1-Carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid, [18F]DCFPyL, a PSMA-based PET imaging agent for prostate cancer. Clin. Cancer Res. 2011, 17, 7645-7653.
-
(2011)
Clin. Cancer Res
, vol.17
, pp. 7645-7653
-
-
Chen, Y.1
Pullambhatla, M.2
Foss, C.A.3
Byun, Y.4
Nimmagadda, S.5
Senthamizhchelvan, S.6
Sgouros, G.7
Mease, R.C.8
Pomper, M.G.9
-
59
-
-
49449089475
-
N-[N-[(S)-1,3-Dicarboxypropyl]carbamoyl]-4-[18F]fluorobenzyl-L-cysteine, [18F]DCFBC: A new imaging probe for prostate cancer
-
Mease, R.C.; Dusich, C.L.; Foss, C.A.; Ravert, H.T.; Dannals, R.F.; Seidel, J.; Prideaux, A.; Fox, J.J.; Sgouros, G.; Kozikowski, A.P., et al. N-[N-[(S)-1,3-Dicarboxypropyl]carbamoyl]-4-[18F]fluorobenzyl-L-cysteine, [18F]DCFBC: A new imaging probe for prostate cancer. Clin. Cancer Res. 2008, 14, 3036-3043.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 3036-3043
-
-
Mease, R.C.1
Dusich, C.L.2
Foss, C.A.3
Ravert, H.T.4
Dannals, R.F.5
Seidel, J.6
Prideaux, A.7
Fox, J.J.8
Sgouros, G.9
Kozikowski, A.P.10
-
60
-
-
84870340190
-
Biodistribution, tumor detection, and radiation dosimetry of 18F-DCFBC, a low-molecular-weight inhibitor of prostate-specific membrane antigen, in patients with metastatic prostate cancer
-
Cho, S.Y.; Gage, K.L.; Mease, R.C.; Senthamizhchelvan, S.; Holt, D.P.; Jeffrey-Kwanisai, A.; Endres, C.J.; Dannals, R.F.; Sgouros, G.; Lodge, M., et al. Biodistribution, tumor detection, and radiation dosimetry of 18F-DCFBC, a low-molecular-weight inhibitor of prostate-specific membrane antigen, in patients with metastatic prostate cancer. J. Nucl. Med. 2012, 53, 1883-1891.
-
(2012)
J. Nucl. Med
, vol.53
, pp. 1883-1891
-
-
Cho, S.Y.1
Gage, K.L.2
Mease, R.C.3
Senthamizhchelvan, S.4
Holt, D.P.5
Jeffrey-Kwanisai, A.6
Endres, C.J.7
Dannals, R.F.8
Sgouros, G.9
Lodge, M.10
-
61
-
-
68249134187
-
How much is life worth: Cetuximab, non-small cell lung cancer, and the $440 billion question
-
Fojo, T.; Grady, C. How much is life worth: Cetuximab, non-small cell lung cancer, and the $440 billion question. J. Natl. Cancer Inst. 2009, 101, 1044-1048.
-
(2009)
J. Natl. Cancer Inst
, vol.101
, pp. 1044-1048
-
-
Fojo, T.1
Grady, C.2
-
62
-
-
77950287975
-
Modulating tumor vasculature through signaling inhibition to improve cytotoxic therapy
-
Maity, A.; Bernhard, E.J. Modulating tumor vasculature through signaling inhibition to improve cytotoxic therapy. Cancer Res. 2010, 70, 2141-2145.
-
(2010)
Cancer Res
, vol.70
, pp. 2141-2145
-
-
Maity, A.1
Bernhard, E.J.2
-
63
-
-
0025148278
-
Continual reassessment method: A practical design for phase I clinical trials in cancer
-
O'Quigley, J.; Pepe, M.; Fisher, L. Continual reassessment method: a practical design for phase I clinical trials in cancer. Biometrics 1990, 46, 33-48.
-
(1990)
Biometrics
, vol.46
, pp. 33-48
-
-
O'Quigley, J.1
Pepe, M.2
Fisher, L.3
-
64
-
-
77949669232
-
An overview of the optimal planning, design, and conduct of phase I studies of new therapeutics
-
LoRusso, P.M.; Boerner, S.A.; Seymour, L. An overview of the optimal planning, design, and conduct of phase I studies of new therapeutics. Clin. Cancer Res. 2010, 16, 1710-1718.
-
(2010)
Clin. Cancer Res
, vol.16
, pp. 1710-1718
-
-
Lorusso, P.M.1
Boerner, S.A.2
Seymour, L.3
-
65
-
-
35648954155
-
Phase I study of oxaliplatin, full-dose gemcitabine, and concurrent radiation therapy in pancreatic cancer
-
Desai, S.P.; Ben-Josef, E.; Normolle, D.P.; Francis, I.R.; Greenson, J.K.; Simeone, D.M.; Chang, A.E.; Colletti, L.M.; Lawrence, T.S.; Zalupski, M.M. Phase I study of oxaliplatin, full-dose gemcitabine, and concurrent radiation therapy in pancreatic cancer. J. Clin. Oncol. 2007, 25, 4587-4592.
-
(2007)
J. Clin. Oncol
, vol.25
, pp. 4587-4592
-
-
Desai, S.P.1
Ben-Josef, E.2
Normolle, D.P.3
Francis, I.R.4
Greenson, J.K.5
Simeone, D.M.6
Chang, A.E.7
Colletti, L.M.8
Lawrence, T.S.9
Zalupski, M.M.10
-
66
-
-
0033637096
-
Sequential designs for phase I clinical trials with late-onset toxicities
-
Cheung, Y.K.; Chappell, R. Sequential designs for phase I clinical trials with late-onset toxicities. Biometrics 2000, 56, 1177-1182.
-
(2000)
Biometrics
, vol.56
, pp. 1177-1182
-
-
Cheung, Y.K.1
Chappell, R.2
-
67
-
-
1342289781
-
Phase I trial using a time-to-event continual reassessment strategy for dose escalation of cisplatin combined with gemcitabine and radiation therapy in pancreatic cancer
-
Muler, J.H.; McGinn, C.J.; Normolle, D.; Lawrence, T.; Brown, D.; Hejna, G.; Zalupski, M.M. Phase I trial using a time-to-event continual reassessment strategy for dose escalation of cisplatin combined with gemcitabine and radiation therapy in pancreatic cancer. J. Clin. Oncol. 2004, 22, 238-243.
-
(2004)
J. Clin. Oncol
, vol.22
, pp. 238-243
-
-
Muler, J.H.1
McGinn, C.J.2
Normolle, D.3
Lawrence, T.4
Brown, D.5
Hejna, G.6
Zalupski, M.M.7
-
68
-
-
79960016350
-
Practical modifications to the time-to-event continual reassessment method for phase I cancer trials with fast patient accrual and late-onset toxicities
-
Polley, M.-Y.C. Practical modifications to the time-to-event continual reassessment method for phase I cancer trials with fast patient accrual and late-onset toxicities. Stat. Med. 2011, 30, 2130-2143.
-
(2011)
Stat. Med
, vol.30
, pp. 2130-2143
-
-
Polley, M.-Y.C.1
-
69
-
-
80052029219
-
Effects of lapatinib monotherapy: Results of a randomised phase II study in therapy-naive patients with locally advanced squamous cell carcinoma of the head and neck
-
Del Campo, J.M.; Hitt, R.; Sebastian, P.; Carracedo, C.; Lokanatha, D.; Bourhis, J.; Temam, S.; Cupissol, D.; de Raucourt, D.; Maroudias, N., et al. Effects of lapatinib monotherapy: Results of a randomised phase II study in therapy-naive patients with locally advanced squamous cell carcinoma of the head and neck. Br. J. Cancer 2011, 105, 618-627.
-
(2011)
Br. J. Cancer
, vol.105
, pp. 618-627
-
-
Del, C.J.M.1
Hitt, R.2
Sebastian, P.3
Carracedo, C.4
Lokanatha, D.5
Bourhis, J.6
Temam, S.7
Cupissol, D.8
de Raucourt, D.9
Maroudias, N.10
-
70
-
-
61349159896
-
Phase 0 clinical trials: Recommendations from the task force on methodology for the development of innovative cancer therapies
-
Kummar, S.; Doroshow, J.H.; Tomaszewski, J.E.; Calvert, A.H.; Lobbezoo, M.; Giaccone, G. Phase 0 clinical trials: Recommendations from the task force on methodology for the development of innovative cancer therapies. Eur. J. Cancer 2009, 45, 741-746.
-
(2009)
Eur. J. Cancer
, vol.45
, pp. 741-746
-
-
Kummar, S.1
Doroshow, J.H.2
Tomaszewski, J.E.3
Calvert, A.H.4
Lobbezoo, M.5
Giaccone, G.6
-
71
-
-
84875039618
-
Combining radiotherapy and cancer immunotherapy: A paradigm shift
-
Formenti, S.C.; Demaria, S. Combining radiotherapy and cancer immunotherapy: A paradigm shift. J. Natl. Cancer Inst. 2013, 105, 256-265.
-
(2013)
J. Natl. Cancer Inst
, vol.105
, pp. 256-265
-
-
Formenti, S.C.1
Demaria, S.2
-
72
-
-
61549108337
-
RTOG 0017: A phase I trial of concurrent gemcitabine/carboplatin or gemcitabine/paclitaxel and radiation therapy ("ping-pong trial") followed by adjuvant chemotherapy for patients with favorable prognosis inoperable stage IIIA/B non-small cell lung cancer
-
Choy, H.; Jain, A.K.; Moughan, J.; Curran, W.; Whipple, G.; Demas, W.F.; Ettinger, D.S. RTOG 0017: A phase I trial of concurrent gemcitabine/carboplatin or gemcitabine/paclitaxel and radiation therapy ("ping-pong trial") followed by adjuvant chemotherapy for patients with favorable prognosis inoperable stage IIIA/B non-small cell lung cancer. J. Thorac. Oncol. 2009, 4, 80-86.
-
(2009)
J. Thorac. Oncol
, vol.4
, pp. 80-86
-
-
Choy, H.1
Jain, A.K.2
Moughan, J.3
Curran, W.4
Whipple, G.5
Demas, W.F.6
Ettinger, D.S.7
-
74
-
-
77954420205
-
Randomized phase II trials: Time for a new era in clinical trial design
-
Mandrekar, S.J.; Sargent, D.J. Randomized phase II trials: Time for a new era in clinical trial design. J. Thorac. Oncol. 2010, 5, 932-934.
-
(2010)
J. Thorac. Oncol
, vol.5
, pp. 932-934
-
-
Mandrekar, S.J.1
Sargent, D.J.2
-
75
-
-
77949673913
-
The design of phase II clinical trials testing cancer therapeutics: Consensus recommendations from the clinical trial design task force of the national cancer institute investigational drug steering committee
-
Seymour, L.; Ivy, S.P.; Sargent, D.; Spriggs, D.; Baker, L.; Rubinstein, L.; Ratain, M.J.; Le Blanc, M.; Stewart, D.; Crowley, J., et al. The design of phase II clinical trials testing cancer therapeutics: Consensus recommendations from the clinical trial design task force of the national cancer institute investigational drug steering committee. Clin. Cancer Res. 2010, 16, 1764-1769.
-
(2010)
Clin. Cancer Res
, vol.16
, pp. 1764-1769
-
-
Seymour, L.1
Ivy, S.P.2
Sargent, D.3
Spriggs, D.4
Baker, L.5
Rubinstein, L.6
Ratain, M.J.7
Le, B.M.8
Stewart, D.9
Crowley, J.10
-
76
-
-
22344447501
-
Randomized phase II designs in cancer clinical trials: Current status and future directions
-
Lee, J.J.; Feng, L. Randomized phase II designs in cancer clinical trials: Current status and future directions. J. Clin. Oncol. 2005, 23, 4450-4457.
-
(2005)
J. Clin. Oncol
, vol.23
, pp. 4450-4457
-
-
Lee, J.J.1
Feng, L.2
-
77
-
-
84855792427
-
Cancer statistics, 2012
-
Siegel, R.; Naishadham, D.; Jemal, A. Cancer statistics, 2012. CA: Cancer J. Clin. 2012, 62, 10-29.
-
(2012)
CA: Cancer J. Clin
, vol.62
, pp. 10-29
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
78
-
-
79957497548
-
Expanding treatment options for metastatic prostate cancer
-
Antonarakis, E.S.; Eisenberger, M.A. Expanding treatment options for metastatic prostate cancer. N. Engl. J. Med. 2011, 364, 2055-2058.
-
(2011)
N. Engl. J. Med
, vol.364
, pp. 2055-2058
-
-
Antonarakis, E.S.1
Eisenberger, M.A.2
-
79
-
-
79960227242
-
Radiotherapy and short-term androgen deprivation for localized prostate cancer
-
Jones, C.U.; Hunt, D.; McGowan, D.G.; Amin, M.B.; Chetner, M.P.; Bruner, D.W.; Leibenhaut, M.H.; Husain, S.M.; Rotman, M.; Souhami, L., et al. Radiotherapy and short-term androgen deprivation for localized prostate cancer. N. Engl. J. Med. 2011, 365, 107-118.
-
(2011)
N. Engl. J. Med
, vol.365
, pp. 107-118
-
-
Jones, C.U.1
Hunt, D.2
McGowan, D.G.3
Amin, M.B.4
Chetner, M.P.5
Bruner, D.W.6
Leibenhaut, M.H.7
Husain, S.M.8
Rotman, M.9
Souhami, L.10
-
80
-
-
45149105820
-
Ten-year follow-up of radiation therapy oncology group protocol 92-02: A phase III trial of the duration of elective androgen deprivation in locally advanced prostate cancer
-
Horwitz, E.M.; Bae, K.; Hanks, G.E.; Porter, A.; Grignon, D.J.; Brereton, H.D.; Venkatesan, V.; Lawton, C.A.; Rosenthal, S.A.; Sandler, H.M., et al. Ten-year follow-up of radiation therapy oncology group protocol 92-02: A phase III trial of the duration of elective androgen deprivation in locally advanced prostate cancer. J. Clin. Oncol. 2008, 26, 2497-2504.
-
(2008)
J. Clin. Oncol
, vol.26
, pp. 2497-2504
-
-
Horwitz, E.M.1
Bae, K.2
Hanks, G.E.3
Porter, A.4
Grignon, D.J.5
Brereton, H.D.6
Venkatesan, V.7
Lawton, C.A.8
Rosenthal, S.A.9
Sandler, H.M.10
-
81
-
-
79961033443
-
Comparative evaluation of radiation treatments for clinically localized prostate cancer: An updated systematic review
-
Bannuru, R.R.; Dvorak, T.; Obadan, N.; Yu, W.W.; Patel, K.; Chung, M.; Ip, S. Comparative evaluation of radiation treatments for clinically localized prostate cancer: An updated systematic review. Annu. Int. Med. 2011, 155, 171-178.
-
(2011)
Annu. Int. Med
, vol.155
, pp. 171-178
-
-
Bannuru, R.R.1
Dvorak, T.2
Obadan, N.3
Yu, W.W.4
Patel, K.5
Chung, M.6
Ip, S.7
-
82
-
-
39149085396
-
Short-term neoadjuvant androgen deprivation therapy and external-beam radiotherapy for locally advanced prostate cancer: Long-term results of RTOG 8610
-
Roach, M.; Bae, K.; Speight, J.; Wolkov, H.B.; Rubin, P.; Lee, R.J.; Lawton, C.; Valicenti, R.; Grignon, D.; Pilepich, M.V. Short-term neoadjuvant androgen deprivation therapy and external-beam radiotherapy for locally advanced prostate cancer: Long-term results of RTOG 8610. J. Clin. Oncol. 2008, 26, 585-591.
-
(2008)
J. Clin. Oncol
, vol.26
, pp. 585-591
-
-
Roach, M.1
Bae, K.2
Speight, J.3
Wolkov, H.B.4
Rubin, P.5
Lee, R.J.6
Lawton, C.7
Valicenti, R.8
Grignon, D.9
Pilepich, M.V.10
-
83
-
-
38349164176
-
Androgen suppression and radiation vs radiation alone for prostate cancer: A randomized trial
-
D'Amico, A.V.; Chen, M.-H.; Renshaw, A.A.; Loffredo, M.; Kantoff, P.W. Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial. JAMA 2008, 299, 289-295.
-
(2008)
JAMA
, vol.299
, pp. 289-295
-
-
D'Amico, A.V.1
Chen, M.-H.2
Renshaw, A.A.3
Loffredo, M.4
Kantoff, P.W.5
-
84
-
-
27744507677
-
Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: Results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial
-
Denham, J.W.; Steigler, A.; Lamb, D.S.; Joseph, D.; Mameghan, H.; Turner, S.; Matthews, J.; Franklin, I.; Atkinson, C.; North, J., et al. Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: Results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial. Lancet Oncol. 2005, 6, 841-850.
-
(2005)
Lancet Oncol
, vol.6
, pp. 841-850
-
-
Denham, J.W.1
Steigler, A.2
Lamb, D.S.3
Joseph, D.4
Mameghan, H.5
Turner, S.6
Matthews, J.7
Franklin, I.8
Atkinson, C.9
North, J.10
-
85
-
-
58149348673
-
Final report of multicenter Canadian Phase III randomized trial of 3 versus 8 months of neoadjuvant androgen deprivation therapy before conventional-dose radiotherapy for clinically localized prostate cancer
-
Crook, J.; Ludgate, C.; Malone, S.; Perry, G.; Eapen, L.; Bowen, J.; Robertson, S.; Lockwood, G. Final report of multicenter Canadian Phase III randomized trial of 3 versus 8 months of neoadjuvant androgen deprivation therapy before conventional-dose radiotherapy for clinically localized prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 2009, 73, 327-333.
-
(2009)
Int. J. Radiat. Oncol. Biol. Phys
, vol.73
, pp. 327-333
-
-
Crook, J.1
Ludgate, C.2
Malone, S.3
Perry, G.4
Eapen, L.5
Bowen, J.6
Robertson, S.7
Lockwood, G.8
-
86
-
-
84880745577
-
Prostate Cancer
-
Hansen, E., Roach III, M., Eds.; Springer: New York, NY, USA
-
Jabbari, S.; Hansen, E.; Roach, M. Prostate Cancer. In Handbook of Evidence-Based Radiation Oncology; Hansen, E., Roach III, M., Eds.; Springer: New York, NY, USA, 2010; pp. 431-477.
-
(2010)
Handbook of Evidence-Based Radiation Oncology
, pp. 431-477
-
-
Jabbari, S.1
Hansen, E.2
Roach, M.3
-
87
-
-
37049023209
-
Long-term results of the M. D. Anderson randomized dose-escalation trial for prostate cancer
-
Kuban, D.A.; Tucker, S.L.; Dong, L.; Starkschall, G.; Huang, E.H.; Cheung, M.R.; Lee, A.K.; Pollack, A. Long-term results of the M. D. Anderson randomized dose-escalation trial for prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 2008, 70, 67-74.
-
(2008)
Int. J. Radiat. Oncol. Biol. Phys
, vol.70
, pp. 67-74
-
-
Kuban, D.A.1
Tucker, S.L.2
Dong, L.3
Starkschall, G.4
Huang, E.H.5
Cheung, M.R.6
Lee, A.K.7
Pollack, A.8
-
88
-
-
24644443217
-
Comparison of conventional-dose vs. high-dose conformal radiation therapy in clinically localized adenocarcinoma of the prostate: A randomized controlled trial
-
Zietman, A.L.; DeSilvio, M.L.; Slater, J.D.; Rossi, C.J.; Miller, D.W.; Adams, J.A.; Shipley, W.U. Comparison of conventional-dose vs. high-dose conformal radiation therapy in clinically localized adenocarcinoma of the prostate: A randomized controlled trial. JAMA 2005, 294, 1233-1239.
-
(2005)
JAMA
, vol.294
, pp. 1233-1239
-
-
Zietman, A.L.1
Desilvio, M.L.2
Slater, J.D.3
Rossi, C.J.4
Miller, D.W.5
Adams, J.A.6
Shipley, W.U.7
-
89
-
-
54049148613
-
Update of Dutch multicenter dose-escalation trial of radiotherapy for localized prostate cancer
-
Al-Mamgani, A.; van Putten, W.L.J.; Heemsbergen, W.D.; van Leenders, G.J.L.H.; Slot, A.; Dielwart, M.F.H.; Incrocci, L.; Lebesque, J.V. Update of Dutch multicenter dose-escalation trial of radiotherapy for localized prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 2008, 72, 980-988.
-
(2008)
Int. J. Radiat. Oncol. Biol. Phys
, vol.72
, pp. 980-988
-
-
Al-Mamgani, A.1
van Putten, W.L.J.2
Heemsbergen, W.D.3
van Leenders, G.J.L.H.4
Slot, A.5
Dielwart, M.F.H.6
Incrocci, L.7
Lebesque, J.V.8
-
90
-
-
78049527402
-
External irradiation with or without long-term androgen suppression for prostate cancer with high metastatic risk: 10-year results of an EORTC randomised study
-
Bolla, M.; van Tienhoven, G.; Warde, P.; Dubois, J.B.; Mirimanoff, R.-O.; Storme, G.; Bernier, J.; Kuten, A.; Sternberg, C.; Billiet, I, et al. External irradiation with or without long-term androgen suppression for prostate cancer with high metastatic risk: 10-year results of an EORTC randomised study. Lancet Oncol. 2010, 11, 1066-1073.
-
(2010)
Lancet Oncol
, vol.11
, pp. 1066-1073
-
-
Bolla, M.1
van Tienhoven, G.2
Warde, P.3
Dubois, J.B.4
Mirimanoff, R.-O.5
Storme, G.6
Bernier, J.7
Kuten, A.8
Sternberg, C.9
Billiet, I.10
-
91
-
-
34648828214
-
Androgen deprivation therapy increases cardiovascular morbidity in men with prostate cancer
-
Saigal, C.S.; Gore, J.L.; Krupski, T.L.; Hanley, J.; Schonlau, M.; Litwin, M.S. Androgen deprivation therapy increases cardiovascular morbidity in men with prostate cancer. Cancer 2007, 110, 1493-1500.
-
(2007)
Cancer
, vol.110
, pp. 1493-1500
-
-
Saigal, C.S.1
Gore, J.L.2
Krupski, T.L.3
Hanley, J.4
Schonlau, M.5
Litwin, M.S.6
-
92
-
-
79957920185
-
Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts
-
Ni, X.; Zhang, Y.; Ribas, J.; Chowdhury, W.H.; Castanares, M.; Zhang, Z.; Laiho, M.; deWeese, T.L.; Lupold, S.E. Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts. J. Clin. Invest. 2011, 121, 2383-2390.
-
(2011)
J. Clin. Invest
, vol.121
, pp. 2383-2390
-
-
Ni, X.1
Zhang, Y.2
Ribas, J.3
Chowdhury, W.H.4
Castanares, M.5
Zhang, Z.6
Laiho, M.7
Deweese, T.L.8
Lupold, S.E.9
-
93
-
-
84875856412
-
Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells
-
Gandhi, N.; Wild, A.T.; Chettiar, S.T.; Aziz, K.; Kato, Y.; Gajula, R.P.; Williams, R.D.; Cades, J.A.; Annadanam, A.; Song, D., et al. Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells. Cancer Biol. Ther. 2013, 14, 347-356.
-
(2013)
Cancer Biol. Ther
, vol.14
, pp. 347-356
-
-
Gandhi, N.1
Wild, A.T.2
Chettiar, S.T.3
Aziz, K.4
Kato, Y.5
Gajula, R.P.6
Williams, R.D.7
Cades, J.A.8
Annadanam, A.9
Song, D.10
-
94
-
-
61449182121
-
Principles of cancer therapy: Oncogene and non-oncogene addiction
-
Luo, J.; Solimini, N.L.; Elledge, S.J. Principles of cancer therapy: Oncogene and non-oncogene addiction. Cell 2009, 136, 823-837.
-
(2009)
Cell
, vol.136
, pp. 823-837
-
-
Luo, J.1
Solimini, N.L.2
Elledge, S.J.3
-
95
-
-
84876084273
-
Targeting heat shock proteins in cancer
-
Jego, G.; Hazoumé, A.; Seigneuric, R.; Garrido, C. Targeting heat shock proteins in cancer. Cancer Lett. 2013, 332, 275-285.
-
(2013)
Cancer Lett
, vol.332
, pp. 275-285
-
-
Jego, G.1
Hazoumé, A.2
Seigneuric, R.3
Garrido, C.4
-
97
-
-
0142125911
-
Hsp90 as a therapeutic target in prostate cancer
-
Solit, D.B.; Scher, H.I.; Rosen, N. Hsp90 as a therapeutic target in prostate cancer. Semin. Oncol. 2003, 30, 709-716.
-
(2003)
Semin. Oncol
, vol.30
, pp. 709-716
-
-
Solit, D.B.1
Scher, H.I.2
Rosen, N.3
-
98
-
-
44349097402
-
Structural studies on the co-chaperone Hop and its complexes with Hsp90
-
Onuoha, S.C.; Coulstock, E.T.; Grossmann, J.G.; Jackson, S.E. Structural studies on the co-chaperone Hop and its complexes with Hsp90. J. Mol. Biol. 2008, 379, 732-744.
-
(2008)
J. Mol. Biol
, vol.379
, pp. 732-744
-
-
Onuoha, S.C.1
Coulstock, E.T.2
Grossmann, J.G.3
Jackson, S.E.4
-
99
-
-
0026731880
-
Evidence for reversible, non-microtubule and non-microfilament-dependent nuclear translocation of hsp90 after heat shock in human fibroblasts
-
Akner, G.; Mossberg, K.; Sundqvist, K.G.; Gustafsson, J.A.; Wikström, A.C. Evidence for reversible, non-microtubule and non-microfilament-dependent nuclear translocation of hsp90 after heat shock in human fibroblasts. Eur. J. Cell Biol. 1992, 58, 356-364.
-
(1992)
Eur. J. Cell Biol
, vol.58
, pp. 356-364
-
-
Akner, G.1
Mossberg, K.2
Sundqvist, K.G.3
Gustafsson, J.A.4
Wikström, A.C.5
-
100
-
-
0027135268
-
Localization and characterization of the 86- and 84-kDa heat shock proteins in Hepa 1c1c7 cells
-
Perdew, G.H.; Hord, N.; Hollenback, C.E.; Welsh, M.J. Localization and characterization of the 86- and 84-kDa heat shock proteins in Hepa 1c1c7 cells. Exp. Cell Res. 1993, 209, 350-356.
-
(1993)
Exp. Cell Res
, vol.209
, pp. 350-356
-
-
Perdew, G.H.1
Hord, N.2
Hollenback, C.E.3
Welsh, M.J.4
-
101
-
-
2942716692
-
Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness
-
Eustace, B.K.; Sakurai, T.; Stewart, J.K.; Yimlamai, D.; Unger, C.; Zehetmeier, C.; Lain, B.; Torella, C.; Henning, S.W.; Beste, G., et al. Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness. Nat. Cell Biol. 2004, 6, 507-514.
-
(2004)
Nat. Cell Biol
, vol.6
, pp. 507-514
-
-
Eustace, B.K.1
Sakurai, T.2
Stewart, J.K.3
Yimlamai, D.4
Unger, C.5
Zehetmeier, C.6
Lain, B.7
Torella, C.8
Henning, S.W.9
Beste, G.10
-
102
-
-
1642268986
-
Hsp90 isoforms: Functions, expression and clinical importance
-
Sreedhar, A.S.; Kalmár, E.; Csermely, P.; Shen, Y.-F. Hsp90 isoforms: Functions, expression and clinical importance. FEBS Lett. 2004, 562, 11-15.
-
(2004)
FEBS Lett
, vol.562
, pp. 11-15
-
-
Sreedhar, A.S.1
Kalmár, E.2
Csermely, P.3
Shen, Y.-F.4
-
103
-
-
79955975429
-
Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer
-
Carver, B.S.; Chapinski, C.; Wongvipat, J.; Hieronymus, H.; Chen, Y.; Chandarlapaty, S.; Arora, V.K.; Le, C.; Koutcher, J.; Scher, H., et al. Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer Cell 2011, 19, 575-586.
-
(2011)
Cancer Cell
, vol.19
, pp. 575-586
-
-
Carver, B.S.1
Chapinski, C.2
Wongvipat, J.3
Hieronymus, H.4
Chen, Y.5
Chandarlapaty, S.6
Arora, V.K.7
Le, C.8
Koutcher, J.9
Scher, H.10
-
104
-
-
79960028514
-
MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks
-
Fraser, M.; Harding, S.M.; Zhao, H.; Coackley, C.; Durocher, D.; Bristow, R.G. MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks. Cell Cycle 2011, 10, 2218-2232.
-
(2011)
Cell Cycle
, vol.10
, pp. 2218-2232
-
-
Fraser, M.1
Harding, S.M.2
Zhao, H.3
Coackley, C.4
Durocher, D.5
Bristow, R.G.6
-
105
-
-
0031895351
-
The hsp90-based chaperone system: Involvement in signal transduction from a variety of hormone and growth factor receptors
-
Pratt, W.B. The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors. Proc. Soc. Exp. Biol. Med. Soc. 1998, 217, 420-434.
-
(1998)
Proc. Soc. Exp. Biol. Med. Soc
, vol.217
, pp. 420-434
-
-
Pratt, W.B.1
-
106
-
-
0036786205
-
Mechanism of antiandrogen action: Key role of hsp90 in conformational change and transcriptional activity of the androgen receptor
-
Georget, V.; Térouanne, B.; Nicolas, J.-C.; Sultan, C. Mechanism of antiandrogen action: Key role of hsp90 in conformational change and transcriptional activity of the androgen receptor. Biochemistry 2002, 41, 11824-11831.
-
(2002)
Biochemistry
, vol.41
, pp. 11824-11831
-
-
Georget, V.1
Térouanne, B.2
Nicolas, J.-C.3
Sultan, C.4
-
107
-
-
42949165854
-
PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival
-
Bozulic, L.; Surucu, B.; Hynx, D.; Hemmings, B.A. PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival. Mol. Cell 2008, 30, 203-213.
-
(2008)
Mol. Cell
, vol.30
, pp. 203-213
-
-
Bozulic, L.1
Surucu, B.2
Hynx, D.3
Hemmings, B.A.4
-
108
-
-
57649219414
-
In vivo analysis of protein kinase B (PKB)/Akt regulation in DNA-PKcs-null mice reveals a role for PKB/Akt in DNA damage response and tumorigenesis
-
Surucu, B.; Bozulic, L.; Hynx, D.; Parcellier, A.; Hemmings, B.A. In vivo analysis of protein kinase B (PKB)/Akt regulation in DNA-PKcs-null mice reveals a role for PKB/Akt in DNA damage response and tumorigenesis. J. Biol. Chem. 2008, 283, 30025-30033.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 30025-30033
-
-
Surucu, B.1
Bozulic, L.2
Hynx, D.3
Parcellier, A.4
Hemmings, B.A.5
-
109
-
-
0028786332
-
Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association
-
Schulte, T.W.; Blagosklonny, M.V.; Ingui, C.; Neckers, L. Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association. J. Biol. Chem. 1995, 270, 24585-24588.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 24585-24588
-
-
Schulte, T.W.1
Blagosklonny, M.V.2
Ingui, C.3
Neckers, L.4
-
110
-
-
9744236616
-
Enhanced tumor cell radiosensitivity and abrogation of G2 and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin
-
Bull, E.E.A.; Dote, H.; Brady, K.J.; Burgan, W.E.; Carter, D.J.; Cerra, M.A.; Oswald, K.A.; Hollingshead, M.G.; Camphausen, K.; Tofilon, P.J. Enhanced tumor cell radiosensitivity and abrogation of G2 and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin. Clin. Cancer Res. 2004, 10, 8077-8084.
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 8077-8084
-
-
Bull, E.E.A.1
Dote, H.2
Brady, K.J.3
Burgan, W.E.4
Carter, D.J.5
Cerra, M.A.6
Oswald, K.A.7
Hollingshead, M.G.8
Camphausen, K.9
Tofilon, P.J.10
-
111
-
-
34547689351
-
Inhibition of Hsp90: A multitarget approach to radiosensitization
-
Camphausen, K.; Tofilon, P.J. Inhibition of Hsp90: A multitarget approach to radiosensitization. Clin. Cancer Res. 2007, 13, 4326-4330.
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 4326-4330
-
-
Camphausen, K.1
Tofilon, P.J.2
-
112
-
-
84880645173
-
Sunitinib plus androgen deprivation and radiation therapy for patients with localized high-risk prostate cancer: Results from a multi-institutional phase I study
-
Corn, P.G.; Song, D.Y.; Heath, E.; Maier, J.; Meyn, R.; Kuban, D.; Depetrillo, T.A.; Mathew, P. Sunitinib plus androgen deprivation and radiation therapy for patients with localized high-risk prostate cancer: Results from a multi-institutional phase I study. Int. J. Radiat. Oncol. Biol. Phys. 2013, 86, 540-545.
-
(2013)
Int. J. Radiat. Oncol. Biol. Phys
, vol.86
, pp. 540-545
-
-
Corn, P.G.1
Song, D.Y.2
Heath, E.3
Maier, J.4
Meyn, R.5
Kuban, D.6
Depetrillo, T.A.7
Mathew, P.8
-
113
-
-
84857914151
-
Phase II study of long-term androgen suppression with bevacizumab and intensity-modulated radiation therapy (IMRT) in high-risk prostate cancer
-
Vuky, J.; Pham, H.T.; Warren, S.; Douglass, E.; Badiozamani, K.; Madsen, B.; Hsi, A.; Song, G. Phase II study of long-term androgen suppression with bevacizumab and intensity-modulated radiation therapy (IMRT) in high-risk prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 2012, 82, e609-e615.
-
(2012)
Int. J. Radiat. Oncol. Biol. Phys
, vol.82
-
-
Vuky, J.1
Pham, H.T.2
Warren, S.3
Douglass, E.4
Badiozamani, K.5
Madsen, B.6
Hsi, A.7
Song, G.8
-
114
-
-
84872815960
-
Radiosensitization in prostate cancer: Mechanisms and targets
-
doi:10.1186/1471-2490-13-4
-
Palacios, D.A.; Miyake, M.; Rosser, C.J. Radiosensitization in prostate cancer: Mechanisms and targets. BMC Urol. 2013, 13, doi:10.1186/1471-2490-13-4.
-
(2013)
BMC Urol
, vol.13
-
-
Palacios, D.A.1
Miyake, M.2
Rosser, C.J.3
-
115
-
-
2542421792
-
A randomized Phase II trial of the antiangiogenic agent SU5416 in hormone-refractory prostate cancer
-
Stadler, W.M.; Cao, D.; Vogelzang, N.J.; Ryan, C.W.; Hoving, K.; Wright, R.; Karrison, T.; Vokes, E.E. A randomized Phase II trial of the antiangiogenic agent SU5416 in hormone-refractory prostate cancer. Clin. Cancer Res. 2004, 10, 3365-3370.
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 3365-3370
-
-
Stadler, W.M.1
Cao, D.2
Vogelzang, N.J.3
Ryan, C.W.4
Hoving, K.5
Wright, R.6
Karrison, T.7
Vokes, E.E.8
-
116
-
-
33750711384
-
A phase I trial of twice-weekly 17-allylamino-demethoxy-geldanamycin in patients with advanced cancer
-
Nowakowski, G.S.; McCollum, A.K.; Ames, M.M.; Mandrekar, S.J.; Reid, J.M.; Adjei, A.A.; Toft, D.O.; Safgren, S.L.; Erlichman, C. A phase I trial of twice-weekly 17-allylamino-demethoxy-geldanamycin in patients with advanced cancer. Clin. Cancer Res. 2006, 12, 6087-6093.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 6087-6093
-
-
Nowakowski, G.S.1
McCollum, A.K.2
Ames, M.M.3
Mandrekar, S.J.4
Reid, J.M.5
Adjei, A.A.6
Toft, D.O.7
Safgren, S.L.8
Erlichman, C.9
-
117
-
-
34250197902
-
Phase I trial of 17-allylamino-17-demethoxygeldanamycin in patients with advanced cancer
-
Solit, D.B.; Ivy, S.P.; Kopil, C.; Sikorski, R.; Morris, M.J.; Slovin, S.F.; Kelly, W.K.; DeLaCruz, A.; Curley, T.; Heller, G., et al. Phase I trial of 17-allylamino-17-demethoxygeldanamycin in patients with advanced cancer. Clin. Cancer Res. 2007, 13, 1775-1782.
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 1775-1782
-
-
Solit, D.B.1
Ivy, S.P.2
Kopil, C.3
Sikorski, R.4
Morris, M.J.5
Slovin, S.F.6
Kelly, W.K.7
Delacruz, A.8
Curley, T.9
Heller, G.10
-
118
-
-
33747691089
-
A phase II trial of 17-(Allylamino)-17-demethoxygeldanamycin in patients with papillary and clear cell renal cell carcinoma
-
Ronnen, E.A.; Kondagunta, G.V.; Ishill, N.; Sweeney, S.M.; Deluca, J.K.; Schwartz, L.; Bacik, J.; Motzer, R.J. A phase II trial of 17-(Allylamino)-17-demethoxygeldanamycin in patients with papillary and clear cell renal cell carcinoma. Invest. New Drugs 2006, 24, 543-546.
-
(2006)
Invest. New Drugs
, vol.24
, pp. 543-546
-
-
Ronnen, E.A.1
Kondagunta, G.V.2
Ishill, N.3
Sweeney, S.M.4
Deluca, J.K.5
Schwartz, L.6
Bacik, J.7
Motzer, R.J.8
-
119
-
-
58149340657
-
Phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with metastatic melanoma
-
Solit, D.B.; Osman, I.; Polsky, D.; Panageas, K.S.; Daud, A.; Goydos, J.S.; Teitcher, J.; Wolchok, J.D.; Germino, F.J.; Krown, S.E., et al. Phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with metastatic melanoma. Clin. Cancer Res. 2008, 14, 8302-8307.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 8302-8307
-
-
Solit, D.B.1
Osman, I.2
Polsky, D.3
Panageas, K.S.4
Daud, A.5
Goydos, J.S.6
Teitcher, J.7
Wolchok, J.D.8
Germino, F.J.9
Krown, S.E.10
-
120
-
-
42349084306
-
NVP-AUY922: A novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis
-
Eccles, S.A.; Massey, A.; Raynaud, F.I.; Sharp, S.Y.; Box, G.; Valenti, M.; Patterson, L.; de Haven Brandon, A.; Gowan, S.; Boxall, F., et al. NVP-AUY922: A novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis. Cancer Res. 2008, 68, 2850-2860.
-
(2008)
Cancer Res
, vol.68
, pp. 2850-2860
-
-
Eccles, S.A.1
Massey, A.2
Raynaud, F.I.3
Sharp, S.Y.4
Box, G.5
Valenti, M.6
Patterson, L.7
de Haven Brandon, A.8
Gowan, S.9
Boxall, F.10
-
121
-
-
0141568014
-
Enhanced cell killing induced by the combination of radiation and the heat shock protein 90 inhibitor 17-allylamino-17- demethoxygeldanamycin: A multitarget approach to radiosensitization
-
Russell, J.S.; Burgan, W.; Oswald, K.A.; Camphausen, K.; Tofilon, P.J. Enhanced cell killing induced by the combination of radiation and the heat shock protein 90 inhibitor 17-allylamino-17- demethoxygeldanamycin: A multitarget approach to radiosensitization. Clin. Cancer Res. 2003, 9, 3749-3755.
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 3749-3755
-
-
Russell, J.S.1
Burgan, W.2
Oswald, K.A.3
Camphausen, K.4
Tofilon, P.J.5
-
122
-
-
23044480581
-
ErbB3 expression predicts tumor cell radiosensitization induced by Hsp90 inhibition
-
Dote, H.; Cerna, D.; Burgan, W.E.; Camphausen, K.; Tofilon, P.J. ErbB3 expression predicts tumor cell radiosensitization induced by Hsp90 inhibition. Cancer Res. 2005, 65, 6967-6975.
-
(2005)
Cancer Res
, vol.65
, pp. 6967-6975
-
-
Dote, H.1
Cerna, D.2
Burgan, W.E.3
Camphausen, K.4
Tofilon, P.J.5
-
123
-
-
74049091229
-
BIIB021, a novel Hsp90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy
-
Yin, X.; Zhang, H.; Lundgren, K.; Wilson, L.; Burrows, F.; Shores, C.G. BIIB021, a novel Hsp90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy. Int. J. Cancer 2010, 126, 1216-1225.
-
(2010)
Int. J. Cancer
, vol.126
, pp. 1216-1225
-
-
Yin, X.1
Zhang, H.2
Lundgren, K.3
Wilson, L.4
Burrows, F.5
Shores, C.G.6
-
124
-
-
30344435264
-
Heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin potentiates the radiation response of tumor cells grown as monolayer cultures and spheroids by inducing apoptosis
-
Machida, H.; Nakajima, S.; Shikano, N.; Nishio, J.; Okada, S.; Asayama, M.; Shirai, M.; Kubota, N. Heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin potentiates the radiation response of tumor cells grown as monolayer cultures and spheroids by inducing apoptosis. Cancer Sci. 2005, 96, 911-917.
-
(2005)
Cancer Sci
, vol.96
, pp. 911-917
-
-
Machida, H.1
Nakajima, S.2
Shikano, N.3
Nishio, J.4
Okada, S.5
Asayama, M.6
Shirai, M.7
Kubota, N.8
-
125
-
-
23244451884
-
Preferential sensitization of tumor cells to radiation by heat shock protein 90 inhibitor geldanamycin
-
Matsumoto, Y.; Machida, H.; Kubota, N. Preferential sensitization of tumor cells to radiation by heat shock protein 90 inhibitor geldanamycin. J. Radiat. Res. 2005, 46, 215-221.
-
(2005)
J. Radiat. Res
, vol.46
, pp. 215-221
-
-
Matsumoto, Y.1
Machida, H.2
Kubota, N.3
-
126
-
-
52149120751
-
Geldanamycin promotes premature mitotic entry and micronucleation in irradiated p53/p21 deficient colon carcinoma cells
-
Moran, D.M.; Gawlak, G.; Jayaprakash, M.S.; Mayar, S.; Maki, C.G. Geldanamycin promotes premature mitotic entry and micronucleation in irradiated p53/p21 deficient colon carcinoma cells. Oncogene 2008, 27, 5567-5577.
-
(2008)
Oncogene
, vol.27
, pp. 5567-5577
-
-
Moran, D.M.1
Gawlak, G.2
Jayaprakash, M.S.3
Mayar, S.4
Maki, C.G.5
-
127
-
-
0033579175
-
DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90
-
Kelland, L.R.; Sharp, S.Y.; Rogers, P.M.; Myers, T.G.; Workman, P. DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90. J. Natl. Cancer Inst. 1999, 91, 1940-1949.
-
(1999)
J. Natl. Cancer Inst
, vol.91
, pp. 1940-1949
-
-
Kelland, L.R.1
Sharp, S.Y.2
Rogers, P.M.3
Myers, T.G.4
Workman, P.5
-
128
-
-
48949119477
-
NVP-AUY922: A small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models
-
doi:10.1186/bcr1996
-
Jensen, M.R.; Schoepfer, J.; Radimerski, T.; Massey, A.; Guy, C.T.; Brueggen, J.; Quadt, C.; Buckler, A.; Cozens, R.; Drysdale, M.J., et al. NVP-AUY922: A small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models. Breast Cancer Res. 2008, 10, doi:10.1186/bcr1996.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Jensen, M.R.1
Schoepfer, J.2
Radimerski, T.3
Massey, A.4
Guy, C.T.5
Brueggen, J.6
Quadt, C.7
Buckler, A.8
Cozens, R.9
Drysdale, M.J.10
-
129
-
-
84865695718
-
Targeting HSP90 by the novel inhibitor NVP-AUY922 reduces growth and angiogenesis of pancreatic cancer
-
Moser, C.; Lang, S.A.; Hackl, C.; Wagner, C.; Scheiffert, E.; Schlitt, H.J.; Geissler, E.K.; Stoeltzing, O. Targeting HSP90 by the novel inhibitor NVP-AUY922 reduces growth and angiogenesis of pancreatic cancer. Anticancer Res. 2012, 32, 2551-2561.
-
(2012)
Anticancer Res
, vol.32
, pp. 2551-2561
-
-
Moser, C.1
Lang, S.A.2
Hackl, C.3
Wagner, C.4
Scheiffert, E.5
Schlitt, H.J.6
Geissler, E.K.7
Stoeltzing, O.8
-
130
-
-
84879589788
-
The PI3K/Akt signalling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma
-
doi:10.3324/haematol.2012.066175
-
Chatterjee, M.; Andrulis, M.; Stühmer, T.; Müller, E.; Hofmann, C.; Steinbrunn, T.; Heimberger, T.; Schraud, H.; Kressmann, S.; Einsele, H.; et al. The PI3K/Akt signalling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma. Haematologica 2012, 97, doi:10.3324/haematol.2012.066175.
-
(2012)
Haematologica
, vol.97
-
-
Chatterjee, M.1
Andrulis, M.2
Stühmer, T.3
Müller, E.4
Hofmann, C.5
Steinbrunn, T.6
Heimberger, T.7
Schraud, H.8
Kressmann, S.9
Einsele, H.10
-
131
-
-
84858009160
-
Strong anti-tumor effect of NVP-AUY922, a novel Hsp90 inhibitor, on non-small cell lung cancer
-
Ueno, T.; Tsukuda, K.; Toyooka, S.; Ando, M.; Takaoka, M.; Soh, J.; Asano, H.; Maki, Y.; Muraoka, T.; Tanaka, N., et al. Strong anti-tumor effect of NVP-AUY922, a novel Hsp90 inhibitor, on non-small cell lung cancer. Lung Cancer 2012, 76, 26-31.
-
(2012)
Lung Cancer
, vol.76
, pp. 26-31
-
-
Ueno, T.1
Tsukuda, K.2
Toyooka, S.3
Ando, M.4
Takaoka, M.5
Soh, J.6
Asano, H.7
Maki, Y.8
Muraoka, T.9
Tanaka, N.10
-
132
-
-
84856832510
-
Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy
-
Ying, W.; Du, Z.; Sun, L.; Foley, K.P.; Proia, D.A.; Blackman, R.K.; Zhou, D.; Inoue, T.; Tatsuta, N.; Sang, J., et al. Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy. Mol. Cancer Ther. 2012, 11, 475-484.
-
(2012)
Mol. Cancer Ther
, vol.11
, pp. 475-484
-
-
Ying, W.1
Du, Z.2
Sun, L.3
Foley, K.P.4
Proia, D.A.5
Blackman, R.K.6
Zhou, D.7
Inoue, T.8
Tatsuta, N.9
Sang, J.10
-
133
-
-
84859857989
-
The HSP90 inhibitor NVP-AUY922 radiosensitizes by abrogation of homologous recombination resulting in mitotic entry with unresolved DNA damage
-
doi:10.1371/journal.pone.0035436
-
Zaidi, S.; McLaughlin, M.; Bhide, S.A.; Eccles, S.A.; Workman, P.; Nutting, C.M.; Huddart, R.A.; Harrington, K.J. The HSP90 inhibitor NVP-AUY922 radiosensitizes by abrogation of homologous recombination resulting in mitotic entry with unresolved DNA damage. PloS One 2012, 7, doi:10.1371/journal.pone.0035436.
-
(2012)
PloS One
, vol.7
-
-
Zaidi, S.1
McLaughlin, M.2
Bhide, S.A.3
Eccles, S.A.4
Workman, P.5
Nutting, C.M.6
Huddart, R.A.7
Harrington, K.J.8
-
134
-
-
79960134213
-
Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage
-
Ha, K.; Fiskus, W.; Rao, R.; Balusu, R.; Venkannagari, S.; Nalabothula, N.R.; Bhalla, K.N. Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage. Mol. Cancer Ther. 2011, 10, 1194-1206.
-
(2011)
Mol. Cancer Ther
, vol.10
, pp. 1194-1206
-
-
Ha, K.1
Fiskus, W.2
Rao, R.3
Balusu, R.4
Venkannagari, S.5
Nalabothula, N.R.6
Bhalla, K.N.7
-
135
-
-
84868116065
-
Chk1 knockdown confers radiosensitization in prostate cancer stem cells
-
Wang, X.; Ma, Z.; Xiao, Z.; Liu, H.; Dou, Z.; Feng, X.; Shi, H. Chk1 knockdown confers radiosensitization in prostate cancer stem cells. Oncol. Rep. 2012, 28, 2247-2254.
-
(2012)
Oncol. Rep
, vol.28
, pp. 2247-2254
-
-
Wang, X.1
Ma, Z.2
Xiao, Z.3
Liu, H.4
Dou, Z.5
Feng, X.6
Shi, H.7
-
136
-
-
84862689468
-
Radiosensitizing effect of the novel Hsp90 inhibitor NVP-AUY922 in human tumour cell lines silenced for Hsp90α
-
Stingl, L.; Niewidok, N.; Müller, N.; Selle, M.; Djuzenova, C.S.; Flentje, M. Radiosensitizing effect of the novel Hsp90 inhibitor NVP-AUY922 in human tumour cell lines silenced for Hsp90α. Strahlentherapie Onkol. 2012, 188, 507-515.
-
(2012)
Strahlentherapie Onkol
, vol.188
, pp. 507-515
-
-
Stingl, L.1
Niewidok, N.2
Müller, N.3
Selle, M.4
Djuzenova, C.S.5
Flentje, M.6
-
137
-
-
84867487415
-
Hsp90 inhibitors NVP-AUY922 and NVP-BEP800 may exert a significant radiosensitization on tumor cells along with a cell type-specific cytotoxicity
-
Niewidok, N.; Wack, L.-J.; Schiessl, S.; Stingl, L.; Katzer, A.; Polat, B.; Sukhorukov, V.L.; Flentje, M.; Djuzenova, C.S. Hsp90 inhibitors NVP-AUY922 and NVP-BEP800 may exert a significant radiosensitization on tumor cells along with a cell type-specific cytotoxicity. Transl. Oncol. 2012, 5, 356-369.
-
(2012)
Transl. Oncol
, vol.5
, pp. 356-369
-
-
Niewidok, N.1
Wack, L.-J.2
Schiessl, S.3
Stingl, L.4
Katzer, A.5
Polat, B.6
Sukhorukov, V.L.7
Flentje, M.8
Djuzenova, C.S.9
-
138
-
-
2442669093
-
Preclinical evaluation of the tyrosine kinase inhibitor SU11248 as a single agent and in combination with "standard of care" therapeutic agents for the treatment of breast cancer
-
Abrams, T.J.; Murray, L.J.; Pesenti, E.; Holway, V.W.; Colombo, T.; Lee, L.B.; Cherrington, J.M.; Pryer, N.K. Preclinical evaluation of the tyrosine kinase inhibitor SU11248 as a single agent and in combination with "standard of care" therapeutic agents for the treatment of breast cancer. Mol. Cancer Ther. 2003, 2, 1011-1021.
-
(2003)
Mol. Cancer Ther
, vol.2
, pp. 1011-1021
-
-
Abrams, T.J.1
Murray, L.J.2
Pesenti, E.3
Holway, V.W.4
Colombo, T.5
Lee, L.B.6
Cherrington, J.M.7
Pryer, N.K.8
-
139
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
-
Mendel, D.B.; Laird, A.D.; Xin, X.; Louie, S.G.; Christensen, J.G.; Li, G.; Schreck, R.E.; Abrams, T.J.; Ngai, T.J.; Lee, L.B., et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship. Clin. Cancer Res. 2003, 9, 327-337.
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
Louie, S.G.4
Christensen, J.G.5
Li, G.6
Schreck, R.E.7
Abrams, T.J.8
Ngai, T.J.9
Lee, L.B.10
-
140
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
O'Farrell, A.-M.; Abrams, T.J.; Yuen, H.A.; Ngai, T.J.; Louie, S.G.; Yee, K.W.H.; Wong, L.M.; Hong, W.; Lee, L.B.; Town, A., et al. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood 2003, 101, 3597-3605.
-
(2003)
Blood
, vol.101
, pp. 3597-3605
-
-
O'Farrell, A.-M.1
Abrams, T.J.2
Yuen, H.A.3
Ngai, T.J.4
Louie, S.G.5
Yee, K.W.H.6
Wong, L.M.7
Hong, W.8
Lee, L.B.9
Town, A.10
-
141
-
-
44349119079
-
SU11248 (sunitinib) sensitizes pancreatic cancer to the cytotoxic effects of ionizing radiation
-
Cuneo, K.C.; Geng, L.; Fu, A.; Orton, D.; Hallahan, D.E.; Chakravarthy, A.B. SU11248 (sunitinib) sensitizes pancreatic cancer to the cytotoxic effects of ionizing radiation. Int. J. Radiat. Oncol. Biol. Phys. 2008, 71, 873-879.
-
(2008)
Int. J. Radiat. Oncol. Biol. Phys
, vol.71
, pp. 873-879
-
-
Cuneo, K.C.1
Geng, L.2
Fu, A.3
Orton, D.4
Hallahan, D.E.5
Chakravarthy, A.B.6
-
142
-
-
0041672482
-
SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models
-
Schueneman, A.J.; Himmelfarb, E.; Geng, L.; Tan, J.; Donnelly, E.; Mendel, D.; McMahon, G.; Hallahan, D.E. SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models. Cancer Res. 2003, 63, 4009-4016.
-
(2003)
Cancer Res
, vol.63
, pp. 4009-4016
-
-
Schueneman, A.J.1
Himmelfarb, E.2
Geng, L.3
Tan, J.4
Donnelly, E.5
Mendel, D.6
McMahon, G.7
Hallahan, D.E.8
-
143
-
-
84865968567
-
Preclinical evaluation of sunitinib, a multi-tyrosine kinase inhibitor, as a radiosensitizer for human prostate cancer
-
doi:10.1186/1748-717X-7-154
-
Brooks, C.; Sheu, T.; Bridges, K.; Mason, K.; Kuban, D.; Mathew, P.; Meyn, R. Preclinical evaluation of sunitinib, a multi-tyrosine kinase inhibitor, as a radiosensitizer for human prostate cancer. Radiat. Oncol. 2012, 7, doi:10.1186/1748-717X-7-154.
-
(2012)
Radiat. Oncol
, vol.7
-
-
Brooks, C.1
Sheu, T.2
Bridges, K.3
Mason, K.4
Kuban, D.5
Mathew, P.6
Meyn, R.7
-
144
-
-
11144223542
-
ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy: Schedule-dependent enhancement of antitumor activity
-
Williams, K.J.; Telfer, B.A.; Brave, S.; Kendrew, J.; Whittaker, L.; Stratford, I.J.; Wedge, S.R. ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy: Schedule-dependent enhancement of antitumor activity. Clin. Cancer Res. 2004, 10, 8587-8593.
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 8587-8593
-
-
Williams, K.J.1
Telfer, B.A.2
Brave, S.3
Kendrew, J.4
Whittaker, L.5
Stratford, I.J.6
Wedge, S.R.7
-
145
-
-
0030971274
-
An antiangiogenic agent (TNP-470) inhibited reoxygenation during fractionated radiotherapy of murine mammary carcinoma
-
Murata, R.; Nishimura, Y.; Hiraoka, M. An antiangiogenic agent (TNP-470) inhibited reoxygenation during fractionated radiotherapy of murine mammary carcinoma. Int. J. Radiat. Oncol. Biol. Phys. 1997, 37, 1107-1113.
-
(1997)
Int. J. Radiat. Oncol. Biol. Phys
, vol.37
, pp. 1107-1113
-
-
Murata, R.1
Nishimura, Y.2
Hiraoka, M.3
-
146
-
-
0028923874
-
Increased efficacy of chemo- and radio-therapy by a hemoglobin solution in the 9L gliosarcoma
-
Teicher, B.A.; Dupuis, N.P.; Emi, Y.; Ikebe, M.; Kakeji, Y.; Menon, K. Increased efficacy of chemo- and radio-therapy by a hemoglobin solution in the 9L gliosarcoma. In Vivo 1995, 9, 11-18.
-
(1995)
In Vivo
, vol.9
, pp. 11-18
-
-
Teicher, B.A.1
Dupuis, N.P.2
Emi, Y.3
Ikebe, M.4
Kakeji, Y.5
Menon, K.6
-
147
-
-
68349128259
-
Hypoxia and radiation therapy: Past history, ongoing research, and future promise
-
Rockwell, S.; Dobrucki, I.T.; Kim, E.Y.; Marrison, S.T.; Vu, V.T. Hypoxia and radiation therapy: Past history, ongoing research, and future promise. Curr. Mol. Med. 2009, 9, 442-458.
-
(2009)
Curr. Mol. Med
, vol.9
, pp. 442-458
-
-
Rockwell, S.1
Dobrucki, I.T.2
Kim, E.Y.3
Marrison, S.T.4
Vu, V.T.5
-
149
-
-
35848934106
-
Supra-additive antitumor effect of sunitinib malate (SU11248, Sutent) combined with docetaxel. A new therapeutic perspective in hormone refractory prostate cancer
-
Guérin, O.; Formento, P.; Lo Nigro, C.; Hofman, P.; Fischel, J.L.; Etienne-Grimaldi, M.C.; Merlano, M.; Ferrero, J.M.; Milano, G. Supra-additive antitumor effect of sunitinib malate (SU11248, Sutent) combined with docetaxel. A new therapeutic perspective in hormone refractory prostate cancer. J. Cancer Res. Clin. Oncol. 2008, 134, 51-57.
-
(2008)
J. Cancer Res. Clin. Oncol
, vol.134
, pp. 51-57
-
-
Guérin, O.1
Formento, P.2
Lo, N.C.3
Hofman, P.4
Fischel, J.L.5
Etienne-Grimaldi, M.C.6
Merlano, M.7
Ferrero, J.M.8
Milano, G.9
-
151
-
-
77955904732
-
Sorafenib and radiation: A promising combination in colorectal cancer
-
Suen, A.W.; Galoforo, S.; Marples, B.; McGonagle, M.; Downing, L.; Martinez, A.A.; Robertson, J.M.; Wilson, G.D. Sorafenib and radiation: a promising combination in colorectal cancer. Int. J. Radiat. Oncol. Biol. Phys. 2010, 78, 213-220.
-
(2010)
Int. J. Radiat. Oncol. Biol. Phys
, vol.78
, pp. 213-220
-
-
Suen, A.W.1
Galoforo, S.2
Marples, B.3
McGonagle, M.4
Downing, L.5
Martinez, A.A.6
Robertson, J.M.7
Wilson, G.D.8
-
152
-
-
34249878526
-
Radiation therapy and sorafenib: Clinical data and rationale for the combination in metastatic renal cell carcinoma
-
Kasibhatla, M.; Steinberg, P.; Meyer, J.; Ernstoff, M.S.; George, D.J. Radiation therapy and sorafenib: Clinical data and rationale for the combination in metastatic renal cell carcinoma. Clin. Genitourin. Cancer 2007, 5, 291-294.
-
(2007)
Clin. Genitourin. Cancer
, vol.5
, pp. 291-294
-
-
Kasibhatla, M.1
Steinberg, P.2
Meyer, J.3
Ernstoff, M.S.4
George, D.J.5
-
154
-
-
27144547509
-
Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells
-
Nam, S.; Kim, D.; Cheng, J.Q.; Zhang, S.; Lee, J.-H.; Buettner, R.; Mirosevich, J.; Lee, F.Y.; Jove, R. Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells. Cancer Res. 2005, 65, 9185-9189.
-
(2005)
Cancer Res
, vol.65
, pp. 9185-9189
-
-
Nam, S.1
Kim, D.2
Cheng, J.Q.3
Zhang, S.4
Lee, J.-H.5
Buettner, R.6
Mirosevich, J.7
Lee, F.Y.8
Jove, R.9
-
155
-
-
0035826165
-
Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells
-
Slack, J.K.; Adams, R.B.; Rovin, J.D.; Bissonette, E.A.; Stoker, C.E.; Parsons, J.T. Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells. Oncogene 2001, 20, 1152-1163.
-
(2001)
Oncogene
, vol.20
, pp. 1152-1163
-
-
Slack, J.K.1
Adams, R.B.2
Rovin, J.D.3
Bissonette, E.A.4
Stoker, C.E.5
Parsons, J.T.6
-
156
-
-
0142058167
-
Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro
-
Recchia, I.; Rucci, N.; Festuccia, C.; Bologna, M.; MacKay, A.R.; Migliaccio, S.; Longo, M.; Susa, M.; Fabbro, D.; Teti, A. Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro. Eur. J. Cancer 2003, 39, 1927-1935.
-
(2003)
Eur. J. Cancer
, vol.39
, pp. 1927-1935
-
-
Recchia, I.1
Rucci, N.2
Festuccia, C.3
Bologna, M.4
Mackay, A.R.5
Migliaccio, S.6
Longo, M.7
Susa, M.8
Fabbro, D.9
Teti, A.10
-
157
-
-
53549085295
-
Activity of the Src-kinase inhibitor AZD0530 in androgen-independent prostate cancer (AIPC): Pre-clinical rationale for a phase II trial
-
Evans, C.; Lara, P.,; Kung, H.; Yang, J. Activity of the Src-kinase inhibitor AZD0530 in androgen-independent prostate cancer (AIPC): Pre-clinical rationale for a phase II trial. J. Clin. Oncol. 2006, 24, 14542.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 14542
-
-
Evans, C.1
Lara, P.2
Kung, H.3
Yang, J.4
-
158
-
-
0034675994
-
Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation
-
Migliaccio, A.; Castoria, G.; di Domenico, M.; de Falco, A.; Bilancio, A.; Lombardi, M.; Barone, M.V.; Ametrano, D.; Zannini, M.S.; Abbondanza, C., et al. Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation. EMBO J. 2000, 19, 5406-5417.
-
(2000)
EMBO J
, vol.19
, pp. 5406-5417
-
-
Migliaccio, A.1
Castoria, G.2
Di, D.M.3
De Falco, A.4
Bilancio, A.5
Lombardi, M.6
Barone, M.V.7
Ametrano, D.8
Zannini, M.S.9
Abbondanza, C.10
-
159
-
-
84857156986
-
Impact of the SRC inhibitor dasatinib on the metastatic phenotype of human prostate cancer cells
-
Rice, L.; Lepler, S.; Pampo, C.; Siemann, D.W. Impact of the SRC inhibitor dasatinib on the metastatic phenotype of human prostate cancer cells. Clin. Exp. Metast. 2012, 29, 133-142.
-
(2012)
Clin. Exp. Metast
, vol.29
, pp. 133-142
-
-
Rice, L.1
Lepler, S.2
Pampo, C.3
Siemann, D.W.4
-
160
-
-
73149115110
-
Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer
-
Yu, E.Y.; Wilding, G.; Posadas, E.; Gross, M.; Culine, S.; Massard, C.; Morris, M.J.; Hudes, G.; Calabrò, F.; Cheng, S., et al. Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer. Clin. Cancer Res. 2009, 15, 7421-7428.
-
(2009)
Clin. Cancer Res
, vol.15
, pp. 7421-7428
-
-
Yu, E.Y.1
Wilding, G.2
Posadas, E.3
Gross, M.4
Culine, S.5
Massard, C.6
Morris, M.J.7
Hudes, G.8
Calabrò, F.9
Cheng, S.10
-
161
-
-
83855162892
-
Dasatinib combined with docetaxel for castration-resistant prostate cancer: Results from a phase 1-2 study
-
Araujo, J.C.; Mathew, P.; Armstrong, A.J.; Braud, E.L.; Posadas, E.; Lonberg, M.; Gallick, G.E.; Trudel, G.C.; Paliwal, P.; Agrawal, S., et al. Dasatinib combined with docetaxel for castration-resistant prostate cancer: Results from a phase 1-2 study. Cancer 2012, 118, 63-71.
-
(2012)
Cancer
, vol.118
, pp. 63-71
-
-
Araujo, J.C.1
Mathew, P.2
Armstrong, A.J.3
Braud, E.L.4
Posadas, E.5
Lonberg, M.6
Gallick, G.E.7
Trudel, G.C.8
Paliwal, P.9
Agrawal, S.10
-
162
-
-
67649396221
-
The Src inhibitor AZD0530 blocks invasion and may act as a radiosensitizer in lung cancer cells
-
Purnell, P.R.; Mack, P.C.; Tepper, C.G.; Evans, C.P.; Green, T.P.; Gumerlock, P.H.; Lara, P.N.; Gandara, D.R.; Kung, H.-J.; Gautschi, O. The Src inhibitor AZD0530 blocks invasion and may act as a radiosensitizer in lung cancer cells. J. Thorac. Oncol. 2009, 4, 448-454.
-
(2009)
J. Thorac. Oncol
, vol.4
, pp. 448-454
-
-
Purnell, P.R.1
Mack, P.C.2
Tepper, C.G.3
Evans, C.P.4
Green, T.P.5
Gumerlock, P.H.6
Lara, P.N.7
Gandara, D.R.8
Kung, H.-J.9
Gautschi, O.10
-
163
-
-
84871300677
-
Dasatinib, a multi-kinase inhibitor increased radiation sensitivity by interfering with nuclear localization of epidermal growth factor receptor and by blocking DNA repair pathways
-
Raju, U.; Riesterer, O.; Wang, Z.-Q.; Molkentine, D.P.; Molkentine, J.M.; Johnson, F.M.; Glisson, B.; Milas, L.; Ang, K.K. Dasatinib, a multi-kinase inhibitor increased radiation sensitivity by interfering with nuclear localization of epidermal growth factor receptor and by blocking DNA repair pathways. Radiother. Oncol. 2012, 105, 241-249.
-
(2012)
Radiother. Oncol
, vol.105
, pp. 241-249
-
-
Raju, U.1
Riesterer, O.2
Wang, Z.-Q.3
Molkentine, D.P.4
Molkentine, J.M.5
Johnson, F.M.6
Glisson, B.7
Milas, L.8
Ang, K.K.9
-
164
-
-
84880711680
-
A phase I study of dasatinib with concurrent chemoradiation for stage III non-small cell lung cancer
-
doi:10.3389/fonc.2012.00056
-
Khurshid, H.; Dipetrillo, T.; Ng, T.; Mantripragada, K.; Birnbaum, A.; Berz, D.; Radie-Keane, K.; Perez, K.; Constantinou, M.; Luppe, D., et al. A phase I study of dasatinib with concurrent chemoradiation for stage III non-small cell lung cancer. Front. Oncol. 2012, 2, doi:10.3389/fonc.2012.00056.
-
(2012)
Front. Oncol
, vol.2
-
-
Khurshid, H.1
Dipetrillo, T.2
Ng, T.3
Mantripragada, K.4
Birnbaum, A.5
Berz, D.6
Radie-Keane, K.7
Perez, K.8
Constantinou, M.9
Luppe, D.10
-
166
-
-
15444349266
-
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer
-
Cairns, P.; Okami, K.; Halachmi, S.; Halachmi, N.; Esteller, M.; Herman, J.G.; Jen, J.; Isaacs, W.B.; Bova, G.S.; Sidransky, D. Frequent inactivation of PTEN/MMAC1 in primary prostate cancer. Cancer Res. 1997, 57, 4997-5000.
-
(1997)
Cancer Res
, vol.57
, pp. 4997-5000
-
-
Cairns, P.1
Okami, K.2
Halachmi, S.3
Halachmi, N.4
Esteller, M.5
Herman, J.G.6
Jen, J.7
Isaacs, W.B.8
Bova, G.S.9
Sidransky, D.10
-
167
-
-
0033200172
-
Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage
-
McMenamin, M.E.; Soung, P.; Perera, S.; Kaplan, I.; Loda, M.; Sellers, W.R. Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage. Cancer Res. 1999, 59, 4291-4296.
-
(1999)
Cancer Res
, vol.59
, pp. 4291-4296
-
-
McMenamin, M.E.1
Soung, P.2
Perera, S.3
Kaplan, I.4
Loda, M.5
Sellers, W.R.6
-
168
-
-
33750565745
-
Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells
-
Cao, C.; Subhawong, T.; Albert, J.M.; Kim, K.W.; Geng, L.; Sekhar, K.R.; Gi, Y.J.; Lu, B. Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells. Cancer Res. 2006, 66, 10040-10047.
-
(2006)
Cancer Res
, vol.66
, pp. 10040-10047
-
-
Cao, C.1
Subhawong, T.2
Albert, J.M.3
Kim, K.W.4
Geng, L.5
Sekhar, K.R.6
Gi, Y.J.7
Lu, B.8
-
169
-
-
84860343387
-
mTOR is a selective effector of the radiation therapy response in androgen receptor-positive prostate cancer
-
Schiewer, M.J.; Den, R.; Hoang, D.T.; Augello, M.A.; Lawrence, Y.R.; Dicker, A.P.; Knudsen, K.E. mTOR is a selective effector of the radiation therapy response in androgen receptor-positive prostate cancer. Endocr. Relat. Cancer 2012, 19, 1-12.
-
(2012)
Endocr. Relat. Cancer
, vol.19
, pp. 1-12
-
-
Schiewer, M.J.1
Den, R.2
Hoang, D.T.3
Augello, M.A.4
Lawrence, Y.R.5
Dicker, A.P.6
Knudsen, K.E.7
-
173
-
-
84874637446
-
Radiosensitization of prostate cancer cells by the dual PI3K/mTOR inhibitor BEZ235 under normoxic and hypoxic conditions
-
Potiron, V.A.; Abderrhamani, R.; Giang, E.; Chiavassa, S.; di Tomaso, E.; Maira, S.-M.; Paris, F.; Supiot, S. Radiosensitization of prostate cancer cells by the dual PI3K/mTOR inhibitor BEZ235 under normoxic and hypoxic conditions. Radiother. Oncol. 2013, 106, 138-146.
-
(2013)
Radiother. Oncol
, vol.106
, pp. 138-146
-
-
Potiron, V.A.1
Abderrhamani, R.2
Giang, E.3
Chiavassa, S.4
di Tomaso, E.5
Maira, S.-M.6
Paris, F.7
Supiot, S.8
-
174
-
-
0030811994
-
Androgen deprivation and radiation therapy: Sequencing studies using the Shionogi in vivo tumor system
-
Zietman, A.L.; Prince, E.A.; Nakfoor, B.M.; Park, J.J. Androgen deprivation and radiation therapy: Sequencing studies using the Shionogi in vivo tumor system. Int. J. Radiat. Oncol. Biol. Phys. 1997, 38, 1067-1070.
-
(1997)
Int. J. Radiat. Oncol. Biol. Phys
, vol.38
, pp. 1067-1070
-
-
Zietman, A.L.1
Prince, E.A.2
Nakfoor, B.M.3
Park, J.J.4
-
175
-
-
0042566204
-
Effect of sequencing of androgen deprivation and radiotherapy on prostate cancer growth
-
Kaminski, J.M.L.; Hanlon, A.L.; Joon, D.L.; Meistrich, M.; Hachem, P.; Pollack, A. Effect of sequencing of androgen deprivation and radiotherapy on prostate cancer growth. Int. J. Radiat. Oncol. Biol. Phys. 2003, 57, 24-28.
-
(2003)
Int. J. Radiat. Oncol. Biol. Phys
, vol.57
, pp. 24-28
-
-
Kaminski, J.M.L.1
Hanlon, A.L.2
Joon, D.L.3
Meistrich, M.4
Hachem, P.5
Pollack, A.6
-
176
-
-
78049384849
-
Radiotherapy combined with hormonal therapy in prostate cancer: The state of the art
-
Milecki, P.; Martenka, P.; Antczak, A.; Kwias, Z. Radiotherapy combined with hormonal therapy in prostate cancer: The state of the art. Cancer Manag. Res. 2010, 2, 243-253.
-
(2010)
Cancer Manag. Res
, vol.2
, pp. 243-253
-
-
Milecki, P.1
Martenka, P.2
Antczak, A.3
Kwias, Z.4
-
177
-
-
0035889395
-
Lack of prostate cancer radiosensitization by androgen deprivation
-
Pollack, A.; Salem, N.; Ashoori, F.; Hachem, P.; Sangha, M.; von Eschenbach, A.C.; Meistrich, M.L. Lack of prostate cancer radiosensitization by androgen deprivation. Int. J. Radiat. Oncol. Biol. Phys. 2001, 51, 1002-1007.
-
(2001)
Int. J. Radiat. Oncol. Biol. Phys
, vol.51
, pp. 1002-1007
-
-
Pollack, A.1
Salem, N.2
Ashoori, F.3
Hachem, P.4
Sangha, M.5
von Eschenbach, A.C.6
Meistrich, M.L.7
-
178
-
-
35448970659
-
No supra-additive effects of goserelin and radiotherapy on clonogenic survival of prostate carcinoma cells in vitro
-
doi:10.1186/1748-717X-2-31
-
Hermann, R.M.; Schwarten, D.; Fister, S.; Grundker, C.; Rave-Frank, M.; Nitsche, M.; Hille, A.; Thelen, P.; Schmidberger, H.; Christiansen, H. No supra-additive effects of goserelin and radiotherapy on clonogenic survival of prostate carcinoma cells in vitro. Radiat. Oncol. 2007, 2, doi:10.1186/1748-717X-2-31.
-
(2007)
Radiat. Oncol
, vol.2
-
-
Hermann, R.M.1
Schwarten, D.2
Fister, S.3
Grundker, C.4
Rave-Frank, M.5
Nitsche, M.6
Hille, A.7
Thelen, P.8
Schmidberger, H.9
Christiansen, H.10
-
179
-
-
8444230022
-
Augmentation of T cell levels and responses induced by androgen deprivation
-
Roden, A.C.; Moser, M.T.; Tri, S.D.; Mercader, M.; Kuntz, S.M.; Dong, H.; Hurwitz, A.A.; McKean, D.J.; Celis, E.; Leibovich, B.C., et al. Augmentation of T cell levels and responses induced by androgen deprivation. J. Immunol. 2004, 173, 6098-6108.
-
(2004)
J. Immunol
, vol.173
, pp. 6098-6108
-
-
Roden, A.C.1
Moser, M.T.2
Tri, S.D.3
Mercader, M.4
Kuntz, S.M.5
Dong, H.6
Hurwitz, A.A.7
McKean, D.J.8
Celis, E.9
Leibovich, B.C.10
-
180
-
-
84870905331
-
Targeting the androgen receptor signalling axis in castration-resistant prostate cancer (CRPC)
-
Tsao, C.-K.; Galsky, M.D.; Small, A.C.; Yee, T.; Oh, W.K. Targeting the androgen receptor signalling axis in castration-resistant prostate cancer (CRPC). BJU Int. 2012, 110, 1580-1588.
-
(2012)
BJU Int
, vol.110
, pp. 1580-1588
-
-
Tsao, C.-K.1
Galsky, M.D.2
Small, A.C.3
Yee, T.4
Oh, W.K.5
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