Radiosensitizing effect of the novel Hsp90 inhibitor NVP-AUY922 in human tumour cell lines silenced for Hsp90α

Strahlentherapie und Onkologie

Volumn 188, Issue 6, 2012, Pages 507-517

  Stingl, L ^a   Niewidok, N ^a   Muller N ^a   Selle, M ^a   Djuzenova, C S ^a   Flentje, M ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Colony survival; Hsp90 inhibition; Ionizing radiation; siRNA; Tumor cells, cultured

Indexed keywords

5 (2,4 DIHYDROXY 5 ISOPROPYLPHENYL) 4 (4 MORPHOLINOMETHYLPHENYL) 3 ISOXAZOLECARBOXYLIC ACID ETHYLAMIDE; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90ALPHA; MESSENGER RNA; PROTEIN KINASE B; RAF PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; RADIATION RESPONSE; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; DNA DAMAGE; DNA REPAIR; GENE SILENCING; HSP90 HEAT-SHOCK PROTEINS; HUMANS; ISOXAZOLES; RADIATION-SENSITIZING AGENTS; RESORCINOLS; RNA, SMALL INTERFERING; TUMOR STEM CELL ASSAY; UP-REGULATION;

EID: 84862689468     PISSN: 01797158     EISSN: 1439099X     Source Type: Journal    
DOI: 10.1007/s00066-012-0080-9     Document Type: Article

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