High-Resolution, Small Animal Radiation Research Platform With X-Ray Tomographic Guidance Capabilities

International Journal of Radiation Oncology Biology Physics

Volumn 71, Issue 5, 2008, Pages 1591-1599

  Wong, John ^a   Armour, Elwood ^a   Kazanzides, Peter ^b   Iordachita, Iulian ^b   Tryggestad, Erik ^a   Deng, Hua ^a   Matinfar, Mohammad ^b   Kennedy, Christopher ^a   Liu, Zejian ^a   Chan, Timothy ^a   Gray, Owen ^b   Verhaegen, Frank ^c   McNutt, Todd ^a   Ford, Eric ^a   DeWeese, Theodore L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Johns Hopkins University   (United States)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Focal laboratory irradiation; Radiation research; Small animal

Indexed keywords

ANIMAL CELL CULTURE; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC RADIOGRAPHY; ELECTRON SOURCES; IRRADIATION; MEDICAL IMAGING; ROTATION; THERMOGRAPHY (TEMPERATURE MEASUREMENT); TOMOGRAPHY; X RAY APPARATUS;

COMPUTED TOMOGRAPHY (CT); CONE-BEAM COMPUTED TOMOGRAPHY (CBCT); CONSTANT VOLTAGE (CV); FLAT-PANEL DETECTORS; FOCAL SPOTS; HIGH RESOLUTIONS; ISOCENTER; RADIATION BEAMS; RESEARCH PLATFORMS; SMALL ANIMALS; TOMOGRAPHIC; TREATMENT PLANNING; X-RAY SOURCES;

IMAGING TECHNIQUES;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLOGICAL MODEL; COMPUTER ASSISTED RADIOTHERAPY; COMPUTER ASSISTED TOMOGRAPHY; CONE BEAM COMPUTED TOMOGRAPHY; CONTROLLED STUDY; MEDICAL RESEARCH; MONTE CARLO METHOD; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; ROBOTICS; TREATMENT PLANNING; X RAY ANALYSIS;

ANIMALS; CONE-BEAM COMPUTED TOMOGRAPHY; EQUIPMENT DESIGN; MICE; MONTE CARLO METHOD; RABBITS; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, CONFORMAL; RATS; ROBOTICS; ROTATION; TECHNOLOGY, RADIOLOGIC;

EID: 47149101666     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2008.04.025     Document Type: Article

References (18)

1. Wong J., Armour E., Oldham M., et al. An image guided small animal radiation research platform. Proceedings of the European Society for Therapeutic Radiology and Oncology (ESTRO 21) Meeting, Praha. Radiat Oncol 64 Suppl. 1 (2002) S61
2. DesRosiers C., Mendonca M., Tyree C., et al. Use of the Leksell Gamma Knife for localized small field lens irradiation in rodents. Tech Cancer Res Treat 2 (2003) 449-454
3. Stojadinovic S., Low D.A., Vicic M., et al. Progress toward a microradiation therapy small animal conformal irradiator. Med Phys 33 (2006) 3834-3845
4. Jaffray D., Moseley D., Chow J., et al. An image-guided irradiator for pre-clinical radiation therapy studies. [Abstract]. Med Phys 33 (2006) 2241
5. Deng H., Kennedy C.W., Armour E., et al. The small-animal radiation research platform (SARRP): Dosimetry of a focused lens system. Phys Med Biol 52 (2007) 2729-2740
6. Graves E.E., Zhou H., Chatterjee R., et al. Design and evaluation of a variable aperture collimator for conformal radiotherapy of small animals using a microCT scanner. Med Phys 34 (2007) 4359-4367
7. Stojadinovic S., Low D.A., Hope A.J., et al. MicroRT-Small animal conformal irradiator. Med Phys 34 (2007) 4706-4716
8. Feldkamp L.A., Davis L.C., and Kress J.W. Practical cone-beam algorithm. J Opt Soc Am A 1 (1984) 612-619
9. Chow J.C., and Leung M.K. Treatment planning for a small animal using Monte Carlo simulation. Med Phys 34 (2007) 4810-4817
10. Devic S., Seuntjens J., Sham E., et al. Precise radiochromic film dosimetry using a flat-bed document scanner. Med Phys 32 (2005) 2245-2253
11. Chiu-Tsao S.T., Ho Y., Shankar R., et al. Energy dependence of response of new high sensitivity radiochromic films for megavoltage and kilovoltage radiation energies. Med Phys 32 (2005) 3350-3354
12. Nowak E., Etienne O., Millet P., et al. Radiation-induced H2AX phosphorylation and neural precursor apoptosis in the developing brain of mice. Radiat Res 165 (2006) 155-164
13. Matinfar M, Gray O, Iordachita I, et al. Small animal radiation research platform: Imaging, mechanics, control and calibration. In: Ayache N, Ourselin S, Maeder AJ, editors. Medical image computing and computer-assisted intervention-MICCAI 2007, Proceedings, Part II. Lecture Notes in Computer Science, Vol. 4792. Berlin/Heidelberg: Springer; 2007. p. 926-934.
14. Quiñones-Hinojosa A., and Chaichana K. The human subventricular zone: A source of new cells and a potential source of brain tumors. Experimental Neurology 205 (2007) 313-324
15. Collis S.J., Neutzel S., Thompson T.L., et al. Hematopoietic progenitor stem cell homing in mice lethally irradiated with differing dose rates of ionizing radiation. Radiat Res 162 (2004) 48-55
16. Liu Z., Armour E., Ford E., et al. Noninvasive evaluation of early radiation-induced pulmonary inflammation via [11C]-PK11195 based PET imaging. [Abstract]. Med Phys 34 (2007) 2623
17. Karikari C., Roy I., Tryggestad E., et al. Targeting the apoptotic machinery in pancreatic cancers using small molecule antagonists of the X-linked inhibitor of apoptosis (XIAP) protein. Mol Cancer Ther 6 (2007) 957-966
18. Collis S.J., and DeWeese T.L. Enhanced radiation response through directed molecular targeting approaches. Cancer Metastasis Rev 23 (2004) 277-292