Functional proteomic screens reveal an essential extracellular role for hsp90α in cancer cell invasiveness

Nature Cell Biology

Volumn 6, Issue 6, 2004, Pages 507-514

  Eustace, Brenda K ^a   Sakurai, Takashi ^a,b   Stewart, Jean K ^a   Yimlamai, Dean ^a   Unger, Christine ^c   Zehetmeier, Carol ^c   Lain, Blanca ^c   Torella, Claudia ^c   Henning, Stefan W ^c   Beste, Gerald ^c   Scroggins, Bradley T ^d   Neckers, Len ^d   Ilag, Leodevico L ^c   Jay, Daniel G ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^c Xerion Pharmaceutical AG   (Germany)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; GELATINASE A; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90ALPHA; HEAT SHOCK PROTEIN 90BETA; UNCLASSIFIED DRUG;

ARTICLE; CANCER INVASION; CELL INVASION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROSARCOMA; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MASS SPECTROMETRY; METASTASIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SCREENING;

BASEMENT MEMBRANE; BINDING SITES; CELL LINE, TUMOR; CELL MEMBRANE; ENZYME INHIBITORS; EXTRACELLULAR MATRIX; FIBROSARCOMA; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MATRIX METALLOPROTEINASE 2; NEOPLASM INVASIVENESS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; PROTEOMICS;

EID: 2942716692     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1131     Document Type: Article

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