Palliative radiotherapy trials for bone metastases: A systematic review

Journal of Clinical Oncology

Volumn 25, Issue 11, 2007, Pages 1423-1436

  Chow, Edward ^a   Harris, Kristin ^a   Fan, Grace ^a   Tsao, May ^a   Sze, Wai M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; ANTIEMETIC AGENT; ANTINEOPLASTIC AGENT;

BONE METASTASIS; CANCER RADIOTHERAPY; CANCER RISK; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; FATIGUE; HUMAN; META ANALYSIS; NAUSEA AND VOMITING; NEUROPATHIC PAIN; PAIN; PALLIATIVE THERAPY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REVIEW; SPINAL CORD COMPRESSION; SYSTEMATIC REVIEW; TREATMENT RESPONSE;

BONE NEOPLASMS; CONFIDENCE INTERVALS; HUMANS; ODDS RATIO; PALLIATIVE CARE; RANDOMIZED CONTROLLED TRIALS;

EID: 34248149008     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2006.09.5281     Document Type: Review

References (51)

1. Ratabatharathorn V, Powers WE, Moss WT, et al: Bone metastases: Review and critical analysis of random allocation trials of local field treatment. Int J Radiat Oncol Biol Phys 44:1-18, 1999
2. McQuay HJ, Collins SL, Carroll D, et al: Radiotherapy for the palliation of painful bone metastases. Cochrane Database of Systematic Reviews 3, 1999, Art. No: CD001793. DOI: 10.1002/14651858.CD001793
3. Wu JSY, Wong R, Johnston M, et al: Meta-analysis of dose-fractionation radiotherapy trials for the palliation of painful bone metastases. Int J Radiat Oncol Biol Phys 55:594-605, 2003
4. Sze WM, Shelley M, Held I, et al: Palliation of metastatic bone pain: Single fraction versus multifraction radiotherapy: A systemic review of randomized trials. Clin Oncol 15:345-352, 2003
5. Sarkar SK, Sarkar S, Pahari B, et al: Multiple and single fraction palliative radiotherapy in bone secondaries: A prospective study. Ind J Radiol Imag 12:281-284, 2002
6. Altundaǧ MB, Üçer AR, Çalikoǧlu T, et al: Single (500 cGy, 800 cGy) and multifraction (300 X 10 cGy) radiotherapy schedules in the treatment of painful bone metastases. Turkish Journal of Hematology-Oncology 12:16-21, 2002
7. Badzio A, Senkus-Konefka E, Jereczek-Fossa BA, et al: 20 Gy in five fractions versus 8 Gy in one fraction in palliative radiotherapy of bone metastases. A multicentre randomized study. Journal of Oncology 53:261-264, 2003
8. Hartsell WF, Scott CB, Watkins Bruner D, et al: Randomized trial of short- versus long-course radiotherapy for palliation of painful bone metastases. J Natl Cancer Inst 97:798-804, 2005
9. Roos DE, Turner SL, O'Brien PC, et al: Randomized trial of 8 Gy in 1 versus 20 Gy in 5 fractions of radiotherapy for neuropathic pain due to bone metastases (Trans-Tasman Radiation Oncology Group, TROG 96.05). Radiother Oncol 75:54-63, 2005
10. Kaasa S, Brenne E, Lund J, et al: Prospective randomized multicentre trial on single fraction radiotherapy (8 Gy X 1) versus multiple fractions (3 Gy X 10) in the treatment of painful bone metastases: Phase III randomized trial. Radiother Oncol 79:278-284, 2006
11. Haddad P, Behrouzi H, Amouzegar-Hashemi F, et al: Single versus multiple fractions of palliative radiotherapy for bone metastases: A randomized clinical trial in Iranian patients. Radiother Oncol 80:S65, 2006 (abstr 223)
12. Steenland E, Leer JW, Van Houwelingen H, et al: The effect of a single fraction compared to multiple fractions on painful bone metastases: A global analysis of the Dutch Bone Metastasis Study. Radiother Oncol 52:101-109, 1999
13. van der Linden YM, Lok JJ, Steenland E, et al: Single fraction radiotherapy is efficacious: A further analysis of the Dutch Bone Metastasis Study controlling for the influence of retreatment. Int J Radiat Oncol Biol Phys 59:528-537, 2004
14. Gaze MN, Kelly CG, Kerr GR, et al: Pain relief and quality of life following radiotherapy for bone metastases: A randomized trial of two fractionation schedules. Radiother Oncol 45:109-116, 1997
15. Bone Pain Trial Working Party: 8 Gy single fraction radiotherapy for the treatment of metastatic skeletal pain: Randomized comparison with a multifraction schedule over 12 months of patient follow-up. Bone Pain Trial Working Party. Radiother Oncol 52:111-121, 1999
16. Foro P, Algara M, Reig A, et al: Randomized prospective trial comparing three schedules of palliative radiotherapy: Preliminary results. Oncologia 21:55-60, 1998
17. Ozsaran Z, Yalman D, Anacek Y, et al: Palliative radiotherapy in bone metastases: Results of a randomized trial comparing three fractionation schedules. Journal of BUON 6:43-48, 2001
18. Price P, Hoskin PJ, Easton D, et al: Prospective randomized trial of single and multifraction radiotherapy schedules in the treatment of painful bony metastases. Radiother Oncol 6:247-255, 1986
19. Cole DJ: A randomized trial of a single treatment versus conventional fractionation in the palliative radiotherapy of painful bone metastases. Clin Oncol 1:59-62, 1989
20. Kagei K, Suzuki K, Shirato H, et al: A randomized trial of single and multifraction radiation therapy for bone metastasis: A preliminary report. Gan No Rinsho 36:2553-2558, 1990
21. Nielsen OS, Bentzen SM, Sandberg E, et al: Randomized trial of single dose versus fractionated palliative radiotherapy of bone metastases. Radiother Oncol 47:233-240, 1998
22. Koswig S, Budach V: Recalcification and pain relief following radiotherapy for bone metastases: A randomized trial of 2 different fractionation schedules (10 X 3 Gy vs. 1 X 8 Gy). Strahlenther Onkol 175:500-508, 1999
23. Kirkbride P, Warde P, Panzarella A, et al: A randomized trial comparing the efficacy of single fraction radiation therapy plus ondansetron with fractionated radiation therapy in the palliation of skeletal metastases. Int J Radiat Oncol Biol Phys 48:185, 2000 (suppl 3)
24. Coia LR, Hanks GE, Martz K, et al: Practice patterns of palliative care for the United States 1984-1985. Int J Radiat Oncol Biol Phys 14:1261-1269, 1988
25. Priestman TJ, Bullimore JA, Godden TP, et al: The Royal College of Radiologists' Fractionation Survey. Clin Oncol 1:39-46, 1989
26. Crellin AM, Marks A, Maher EJ: Why don't British radiotherapists give single fractions of radiotherapy for bone metastases? Clin Oncol 1:63-66, 1989
27. Lawton PA, Maher EJ: Treatment strategies for advanced and metastatic cancer in Europe. Radiother Oncol 22:1-6, 1991
28. Maher EJ, Coia L, Duncan G, et al: Treatment strategies in advanced and metastatic cancer: Differences in attitude between the USA, Canada and Europe. Int J Radiat Oncol Biol Phys 23:239-244, 1992
29. Duncan G, Duncan W, Maher EJ: Patterns of palliative radiotherapy in Canada. Clin Oncol 5:92-97, 1993
30. Stevens G, Firth I: Patterns of fractionation for palliation of bone metastases. Australas Radiol 39:31-35, 1995
31. Ben-Josef E, Shamsa F, Williams AO, et al: Radiotherapeutic management of osseous metastases: A survey of current practices of care. Int J Radiat Oncol Biol Phys 40:915-921, 1998
32. Hartsell WF, Shah AB, Graney M, et al: Palliation of bone metastases in the USA: A survey of patterns of practice. Support Care Cancer 6:175, 1998
33. Chow E, Danjoux C, Wong R, et al: Palliation of bone metastases: A survey of patterns of practice among Canadian radiation oncologists. Radiother Oncol 56:305-314, 2000
34. Lievens Y, Kesteloot K, Rijnders A, et al: Differences in palliative radiotherapy for bone metastases within Western European countries. Radiother Oncol 56:297-303, 2000
35. Roos DE: Continuing reluctance to use single fractions of radiotherapy for metastatic bone pain: An Australian and New Zealand practice survey and literature review. Radiother Oncol 56:315-322, 2000
36. Möller TR, Brorsson B, Ceberg J, et al: A prospective survey of radiotherapy practice 2001 in Sweden. Acta Oncol 42:387-410, 2003
37. Gupta T, Sarin R: Palliative radiation therapy for painful vertebral metastases - a practice survey. Cancer 101:2892-2896, 2004
38. Williams MV, James ND, Summers ET, et al: National survey of radiotherapy fractionation practice in 2003. Clin Oncol 18:3-14, 2006
39. van der Linden YM, Leer JWH: Impact of randomized trial-outcome in the treatment of painful bone metastases; patterns of practice among radiation oncologists. A matter of believers vs. non-believers? Radiother Oncol 56:279-281, 2000
40. Chandler SS, Sarin R: Single fraction radiotherapy for bone metastases: Are all questions answered? Radiother Oncol 52:191-193, 1999
41. Shakespeare TP, Thiagarajan A, Gebski V: Evaluation of the quality of radiotherapy randomized trials for painful bone metastases. Cancer 103:1976-1981, 2005
42. Khan KS, Daya S, Jadad AR: The importance of quality of primary studies in producing unbiased systematic reviews. Arch Intern Med 156:661-666, 1996
43. Glastein E. Letters to the editor: In response to Drs. Arriagada and Pignon. Int J Radiat Oncol Biol Phys 52:1141-1142, 2002
44. Tong D, Gillick L, Hendrickson FR: The palliation of symptomatic osseous metastases: Final results of the study by the Radiation Therapy Oncology Group. Cancer 50:893-899, 1982
45. Blitzer PH: Reanalysis of the RTOG study of the palliation of symptomatic osseous metastasis. Cancer 55:1468-1472, 1985
46. Chow E, Wu JSY, Hoskin P, et al: International consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases. Radiother Oncol 64:275-280, 2002
47. Chow E, Davis L, Holden L, et al: A comparison of radiotherapy outcomes of bone metastases employing international consensus endpoints and traditional endpoints. Supportive Cancer Therapy 1:173-178, 2004
48. van der Hout WB, van der Linder YM, Steenland E, et al: Single- versus multiple-fraction radiotherapy in patients with painful bone metastases: Cost-utility analysis based on a randomized trial. J Natl Cancer Inst 95:222-229, 2003
49. Kachnic L, Berk L: Palliative single-fraction radiation therapy: How much more evidence is needed? J Natl Cancer Inst 97:786-788, 2005
50. Chow E, Coia L, Wu J, et al: This house believes that multiple-fraction radiotherapy is a barrier to referral for palliative radiotherapy for bone metastases. Current Oncology 9:60-66, 2002
51. Wu JS, Wong RK, Lloyd NS, et al: Radiotherapy fractionation for the palliation of uncomplicated painful bone metastases: An evidence-based practice guideline. BMC Cancer 4:71, 2004