The membrane-active tri-block copolymer Pluronic F-68 profoundly rescues rat hippocampal neurons from oxygen-glucose deprivation-induced death through early inhibition of apoptosis

Journal of Neuroscience

Volumn 33, Issue 30, 2013, Pages 12287-12299

  Shelat, Phullara B ^a   Plant, Leigh D ^a   Wang, Janice C ^a   Lee, Elizabeth ^a   Marks, Jeremy D ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CASPASE; CYTOCHROME C; GLUCOSE; LIPOCORTIN 5; OXYGEN; PHOSPHATIDYLSERINE; POLOXAMER; PROTEIN BAX;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL FRACTIONATION; CELL SURVIVAL; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ENZYME ACTIVITY; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; NERVE EXCITABILITY; NERVE POTENTIAL; NICK END LABELING; NONHUMAN; NUTRITION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; WESTERN BLOTTING;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 1; CASPASE INHIBITORS; CELL HYPOXIA; CYTOCHROMES C; ENZYME ACTIVATION; FEMALE; FETUS; GLUCOSE; HIPPOCAMPUS; MALE; MEMBRANE POTENTIALS; MITOCHONDRIA; NEURONS; OXYGEN; PATCH-CLAMP TECHNIQUES; POLYETHYLENE GLYCOLS; PREGNANCY; PRIMARY CELL CULTURE; PROPYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84880605686     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5731-12.2013     Document Type: Article

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