Bid-induced mitochondrial membrane permeabilization waves propagated by local reactive oxygen species (ROS) signaling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 12, 2012, Pages 4497-4502

  Garcia Perez, Cecilia ^a   Roy, Soumya Sinha ^a,b   Naghdi, Shamim ^a   Lin, Xuena ^a   Davies, Erika ^a   Hajnóczky, György ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

Author keywords

Calcium; Cell death; Intermitochondrial signaling; Outer mitochondrial membrane; Wave propagation

Indexed keywords

CASPASE; CYTOCHROME C; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PROTEIN BAX; PROTEIN BID; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL ORGANELLE; CELL STRAIN HEPG2; CONTROLLED STUDY; ENZYME ACTIVATION; FLOW CYTOMETRY; GENETIC TRANSFECTION; HEART MUSCLE CELL; HUMAN; HUMAN CELL; INHIBITION KINETICS; MEMBRANE DEPOLARIZATION; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ADENYLATE KINASE; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CALCIUM; CELL DEATH; CYTOCHROMES C; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; PERMEABILITY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUPEROXIDES; TIME FACTORS;

EID: 84858678834     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1118244109     Document Type: Article

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