Mechanical membrane injury induces axonal beading through localized activation of calpain

Experimental Neurology

Volumn 219, Issue 2, 2009, Pages 553-561

  Kilinc, Devrim ^a   Gallo, Gianluca ^b   Barbee, Kenneth A ^a  

^a DREXEL UNIVERSITY   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Axonal bead formation; Calcium; Calpain; Diffuse axonal injury; Mechanoporation; Mitochondria; Poloxamer 188

Indexed keywords

CALCIUM; CALPAIN; POLOXAMER;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DIFFUSE AXONAL INJURY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; MEMBRANE DAMAGE; MEMBRANE PERMEABILITY; MITOCHONDRION; NERVE FIBER MEMBRANE; NONHUMAN; NUCLEAR PORE; PRIORITY JOURNAL; PROTEIN TARGETING; SHEAR STRESS;

ANALYSIS OF VARIANCE; ANIMALS; AXONAL TRANSPORT; AXONS; CALCIUM; CALPAIN; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; CHELATING AGENTS; CHICK EMBRYO; MICROSPHERES; MITOCHONDRIA; NEURONS; PROSENCEPHALON; STRESS, MECHANICAL; TIME FACTORS;

EID: 69749087083     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2009.07.014     Document Type: Article

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