Loss of Jak2 impairs endothelial function by attenuating Raf-1/MEK1/Sp-1 signaling along with altered eNOS activities

American Journal of Pathology

Volumn 183, Issue 2, 2013, Pages 617-625

  Yang, Ping ^a,b   Zhang, Yawen ^b,c   Pang, Junfeng ^a   Zhang, Shu ^a   Yu, Qilin ^a   He, Long ^a   Wagner, Kay Uwe ^d   Zhou, Zhiguang ^e   Wang, Cong Yi ^a,b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c TIANJIN MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^e CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; JANUS KINASE 2; MATRIGEL; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; RAF PROTEIN; TAMOXIFEN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY PERFUSION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EX VIVO STUDY; HINDLIMB; HOMEOSTASIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

ANIMALS; AORTA; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HINDLIMB; ISCHEMIA; JANUS KINASE 2; MALE; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NITRIC OXIDE SYNTHASE TYPE III; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-RAF; TAMOXIFEN; VASODILATOR AGENTS;

EID: 84880604454     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.04.007     Document Type: Article

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