-
1
-
-
34548851944
-
Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome
-
Pine SR, Guo Q, Yin C, Jayabose S, Druschel CM, Sandoval C. Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome. Blood. 2007;110(6): 2128-2131.
-
(2007)
Blood
, vol.110
, Issue.6
, pp. 2128-2131
-
-
Pine, S.R.1
Guo, Q.2
Yin, C.3
Jayabose, S.4
Druschel, C.M.5
Sandoval, C.6
-
2
-
-
33745076542
-
A prospective study of the natural history of transient leukemia (TL) in neonates with Down syndrome (DS): Children's Oncology Group (COG) study POG-9481
-
Massey GV, Zipursky A, Chang MN, et al; Children's Oncology Group (COG). A prospective study of the natural history of transient leukemia (TL) in neonates with Down syndrome (DS): Children's Oncology Group (COG) study POG-9481. Blood. 2006;107(12):4606-4613.
-
(2006)
Blood
, vol.107
, Issue.12
, pp. 4606-4613
-
-
Massey, G.V.1
Zipursky, A.2
Chang, M.N.3
-
4
-
-
35648968664
-
Acute megakaryoblastic leukemia in Down syndrome
-
Hitzler JK. Acute megakaryoblastic leukemia in Down syndrome. Pediatr Blood Cancer. 2007; 49(7 Suppl):1066-1069.
-
(2007)
Pediatr Blood Cancer.
, vol.49
, Issue.7
, pp. 1066-1069
-
-
Hitzler, J.K.1
-
5
-
-
0038142350
-
GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome
-
Hitzler JK, Cheung J, Li Y, Scherer SW, Zipursky A. GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome. Blood. 2003;101(11):4301-4304.
-
(2003)
Blood
, vol.101
, Issue.11
, pp. 4301-4304
-
-
Hitzler, J.K.1
Cheung, J.2
Li, Y.3
Scherer, S.W.4
Zipursky, A.5
-
6
-
-
0036727413
-
Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome
-
Wechsler J, Greene M, McDevitt MA, Anastasi J, Karp JE, Le Beau MM, Crispino JD. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nat Genet. 2002; 32(1):148-152.
-
(2002)
Nat Genet.
, vol.32
, Issue.1
, pp. 148-152
-
-
Wechsler, J.1
Greene, M.2
McDevitt, M.A.3
Anastasi, J.4
Karp, J.E.5
Le Beau, M.M.6
Crispino, J.D.7
-
7
-
-
0037906527
-
Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder
-
Groet J, McElwaine S, Spinelli M, et al. Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder. Lancet. 2003;361(9369):1617-1620.
-
(2003)
Lancet.
, vol.361
, Issue.9369
, pp. 1617-1620
-
-
Groet, J.1
McElwaine, S.2
Spinelli, M.3
-
8
-
-
0141889275
-
Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome
-
Xu G, Nagano M, Kanezaki R, et al. Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome. Blood. 2003;102(8):2960-2968.
-
(2003)
Blood
, vol.102
, Issue.8
, pp. 2960-2968
-
-
Xu, G.1
Nagano, M.2
Kanezaki, R.3
-
9
-
-
0028800317
-
Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis
-
Weiss MJ, Orkin SH. Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis. Proc Natl Acad Sci USA. 1995;92(21):9623-9627.
-
(1995)
Proc Natl Acad Sci USA.
, vol.92
, Issue.21
, pp. 9623-9627
-
-
Weiss, M.J.1
Orkin, S.H.2
-
10
-
-
13444270650
-
GATA1 function, a paradigm for transcription factors in hematopoiesis
-
Ferreira R, Ohneda K, Yamamoto M, Philipsen S. GATA1 function, a paradigm for transcription factors in hematopoiesis. Mol Cell Biol. 2005; 25(4):1215-1227.
-
(2005)
Mol Cell Biol.
, vol.25
, Issue.4
, pp. 1215-1227
-
-
Ferreira, R.1
Ohneda, K.2
Yamamoto, M.3
Philipsen, S.4
-
11
-
-
0023682893
-
Cytogenetic findings and clinical features in acute leukemia and transient myeloproliferative disorder in Down's syndrome
-
Hayashi Y, Eguchi M, Sugita K, et al. Cytogenetic findings and clinical features in acute leukemia and transient myeloproliferative disorder in Down's syndrome. Blood. 1988;72(1):15-23.
-
(1988)
Blood
, vol.72
, Issue.1
, pp. 15-23
-
-
Hayashi, Y.1
Eguchi, M.2
Sugita, K.3
-
12
-
-
38949098169
-
Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: An iBFM-SG study
-
Forestier E, Izraeli S, Beverloo B, et al. Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: an iBFM-SG study. Blood. 2008; 111(3):1575-1583.
-
(2008)
Blood
, vol.111
, Issue.3
, pp. 1575-1583
-
-
Forestier, E.1
Izraeli, S.2
Beverloo, B.3
-
13
-
-
33749577270
-
Development of acute megakaryoblastic leukemia from a minor clone in a Down syndrome patient with clinically overt transient myeloproliferative disorder
-
Xu G, Kato K, Toki T, Takahashi Y, Terui K, Ito E. Development of acute megakaryoblastic leukemia from a minor clone in a Down syndrome patient with clinically overt transient myeloproliferative disorder. J Pediatr Hematol Oncol. 2006;28(10): 696-698.
-
(2006)
J Pediatr Hematol Oncol.
, vol.28
, Issue.10
, pp. 696-698
-
-
Xu, G.1
Kato, K.2
Toki, T.3
Takahashi, Y.4
Terui, K.5
Ito, E.6
-
14
-
-
33846268788
-
Molecular insights into Down syndrome-associated leukemia
-
Vyas P, Crispino JD. Molecular insights into Down syndrome-associated leukemia. Curr Opin Pediatr. 2007;19(1):9-14.
-
(2007)
Curr Opin Pediatr.
, vol.19
, Issue.1
, pp. 9-14
-
-
Vyas, P.1
Crispino, J.D.2
-
15
-
-
38349119730
-
Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome
-
Kirsammer G, Jilani S, Liu H, Davis E, Gurbuxani S, Le Beau MM, Crispino JD. Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome. Blood. 2008;111(2): 767-775.
-
(2008)
Blood
, vol.111
, Issue.2
, pp. 767-775
-
-
Kirsammer, G.1
Jilani, S.2
Liu, H.3
Davis, E.4
Gurbuxani, S.5
Le Beau, M.M.6
Crispino, J.D.7
-
16
-
-
61849124643
-
Hematopoietic defects in the Ts1Cje mouse model of Down syndrome
-
Carmichael CL, Majewski IJ, Alexander WS, Metcalf D, Hilton DJ, Hewitt CA, Scott HS. Hematopoietic defects in the Ts1Cje mouse model of Down syndrome. Blood. 2009;113(9): 1929-1937.
-
(2009)
Blood
, vol.113
, Issue.9
, pp. 1929-1937
-
-
Carmichael, C.L.1
Majewski, I.J.2
Alexander, W.S.3
Metcalf, D.4
Hilton, D.J.5
Hewitt, C.A.6
Scott, H.S.7
-
17
-
-
77951074754
-
Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome
-
Alford KA, Slender A, Vanes L, et al. Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome. Blood. 2010;115(14):2928-2937.
-
(2010)
Blood
, vol.115
, Issue.14
, pp. 2928-2937
-
-
Alford, K.A.1
Slender, A.2
Vanes, L.3
-
18
-
-
84857814609
-
Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome
-
Malinge S, Bliss-Moreau M, Kirsammer G, Diebold L, Chlon T, Gurbuxani S, Crispino JD. Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome. J Clin Invest. 2012;122(3):948-962.
-
(2012)
J Clin Invest.
, vol.122
, Issue.3
, pp. 948-962
-
-
Malinge, S.1
Bliss-Moreau, M.2
Kirsammer, G.3
Diebold, L.4
Chlon, T.5
Gurbuxani, S.6
Crispino, J.D.7
-
19
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med. 1997;3(7):730-737.
-
(1997)
Nat Med.
, vol.3
, Issue.7
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
20
-
-
79955711142
-
Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse
-
Clappier E, Gerby B, Sigaux F, et al. Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse. J Exp Med. 2011;208(4): 653-661.
-
(2011)
J Exp Med.
, vol.208
, Issue.4
, pp. 653-661
-
-
Clappier, E.1
Gerby, B.2
Sigaux, F.3
-
21
-
-
78751661556
-
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells
-
Notta F, Mullighan CG, Wang JCY, et al. Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells. Nature. 2011; 469(7330):362-367.
-
(2011)
Nature
, vol.469
, Issue.7330
, pp. 362-367
-
-
Notta, F.1
Mullighan, C.G.2
Wang, J.C.Y.3
-
22
-
-
78751644099
-
Genetic variegation of clonal architecture and propagating cells in leukaemia
-
Anderson K, Lutz C, van Delft FW, et al. Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature. 2011;469(7330):356-361.
-
(2011)
Nature
, vol.469
, Issue.7330
, pp. 356-361
-
-
Anderson, K.1
Lutz, C.2
Van Delft, F.W.3
-
23
-
-
0042243661
-
Complete reconstitution of human lymphocytes from cord blood CD341 cells using the NOD/SCID/gammacnull mice model
-
Hiramatsu H, Nishikomori R, Heike T, Ito M, Kobayashi K, Katamura K, Nakahata T. Complete reconstitution of human lymphocytes from cord blood CD341 cells using the NOD/SCID/gammacnull mice model. Blood. 2003;102(3):873-880.
-
(2003)
Blood
, vol.102
, Issue.3
, pp. 873-880
-
-
Hiramatsu, H.1
Nishikomori, R.2
Heike, T.3
Ito, M.4
Kobayashi, K.5
Katamura, K.6
Nakahata, T.7
-
24
-
-
35948953564
-
Human cord blood CD341 cells develop into hepatocytes in the livers of NOD/SCID/gamma(c)null mice through cell fusion
-
Fujino H, Hiramatsu H, Tsuchiya A, et al. Human cord blood CD341 cells develop into hepatocytes in the livers of NOD/SCID/gamma(c)null mice through cell fusion. FASEB J. 2007;21(13):3499-3510.
-
(2007)
FASEB J.
, vol.21
, Issue.13
, pp. 3499-3510
-
-
Fujino, H.1
Hiramatsu, H.2
Tsuchiya, A.3
-
25
-
-
66649112854
-
Frequent inactivation of A20 in B-cell lymphomas
-
Kato M, Sanada M, Kato I, et al. Frequent inactivation of A20 in B-cell lymphomas. Nature. 2009;459(7247):712-716.
-
(2009)
Nature
, vol.459
, Issue.7247
, pp. 712-716
-
-
Kato, M.1
Sanada, M.2
Kato, I.3
-
26
-
-
84858225214
-
Identification of hepatic niche harboring human acute lymphoblastic leukemic cells via the SDF-1/CXCR4 axis
-
Kato I, Niwa A, Heike T, et al. Identification of hepatic niche harboring human acute lymphoblastic leukemic cells via the SDF-1/CXCR4 axis. PLoS ONE. 2011;6(11):e27042.
-
(2011)
PLoS ONE.
, vol.6
, Issue.11
, pp. e27042
-
-
Kato, I.1
Niwa, A.2
Heike, T.3
-
27
-
-
77952422299
-
Functional differences between myeloid leukemia-initiating and transient leukemia cells in Down's syndrome
-
Chen J, Li Y, Doedens M, Wang P, Shago M, Dick JE, Hitzler JK. Functional differences between myeloid leukemia-initiating and transient leukemia cells in Down's syndrome. Leukemia. 2010;24(5):1012-1017.
-
(2010)
Leukemia.
, vol.24
, Issue.5
, pp. 1012-1017
-
-
Chen, J.1
Li, Y.2
Doedens, M.3
Wang, P.4
Shago, M.5
Dick, J.E.6
Hitzler, J.K.7
-
28
-
-
18344410760
-
NOD/SCID/gamma(c)(null) mouse: An excellent recipient mouse model for engraftment of human cells
-
Ito M, Hiramatsu H, Kobayashi K, et al. NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells. Blood. 2002;100(9):3175-3182.
-
(2002)
Blood
, vol.100
, Issue.9
, pp. 3175-3182
-
-
Ito, M.1
Hiramatsu, H.2
Kobayashi, K.3
-
29
-
-
0030715023
-
Flow cytometry CD45 gating for immunophenotyping of acute myeloid leukemia
-
Lacombe F, Durrieu F, Briais A, et al. Flow cytometry CD45 gating for immunophenotyping of acute myeloid leukemia. Leukemia. 1997;11(11): 1878-1886.
-
(1997)
Leukemia.
, vol.11
, Issue.11
, pp. 1878-1886
-
-
Lacombe, F.1
Durrieu, F.2
Briais, A.3
-
30
-
-
0023114585
-
Differentiation of blast cells from a Down's syndrome patient with transient myeloproliferative disorder
-
Suda J, Eguchi M, Akiyama Y, et al. Differentiation of blast cells from a Down's syndrome patient with transient myeloproliferative disorder. Blood. 1987;69(2):508-512.
-
(1987)
Blood
, vol.69
, Issue.2
, pp. 508-512
-
-
Suda, J.1
Eguchi, M.2
Akiyama, Y.3
-
31
-
-
63449115797
-
Unbalanced chromosome 1 abnormalities leading to partial trisomy 1q in four infants with Down syndrome and acute megakaryocytic leukemia
-
Silva ML, do Socorro Pombo-de-Oliveira M, Raimondi SC, et al. Unbalanced chromosome 1 abnormalities leading to partial trisomy 1q in four infants with Down syndrome and acute megakaryocytic leukemia. Mol Cytogenet. 2009;2:7.
-
(2009)
Mol Cytogenet.
, vol.2
, pp. 7
-
-
Silva, M.L.1
Do Socorro Pombo-De-Oliveira, M.2
Raimondi, S.C.3
-
32
-
-
84864255882
-
The origin and evolution of mutations in acute myeloid leukemia
-
Welch JS, Ley TJ, Link DC, et al. The origin and evolution of mutations in acute myeloid leukemia. Cell. 2012;150(2):264-278.
-
(2012)
Cell.
, vol.150
, Issue.2
, pp. 264-278
-
-
Welch, J.S.1
Ley, T.J.2
Link, D.C.3
-
33
-
-
12144287045
-
Natural history of GATA1 mutations in Down syndrome
-
Ahmed M, Sternberg A, Hall G, et al. Natural history of GATA1 mutations in Down syndrome. Blood. 2004;103(7):2480-2489.
-
(2004)
Blood
, vol.103
, Issue.7
, pp. 2480-2489
-
-
Ahmed, M.1
Sternberg, A.2
Hall, G.3
-
34
-
-
84856013431
-
Clonal evolution in cancer
-
Greaves M, Maley CC. Clonal evolution in cancer. Nature. 2012;481(7381):306-313.
-
(2012)
Nature
, vol.481
, Issue.7381
, pp. 306-313
-
-
Greaves, M.1
Maley, C.C.2
-
35
-
-
0346966816
-
Fetal origin of the GATA1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome
-
Shimada A, Xu G, Toki T, Kimura H, Hayashi Y, Ito E. Fetal origin of the GATA1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome. Blood. 2004; 103(1):366.
-
(2004)
Blood
, vol.103
, Issue.1
, pp. 366
-
-
Shimada, A.1
Xu, G.2
Toki, T.3
Kimura, H.4
Hayashi, Y.5
Ito, E.6
-
36
-
-
11144242549
-
Origins of leukaemia in children with Down syndrome
-
Hitzler JK, Zipursky A. Origins of leukaemia in children with Down syndrome. Nat Rev Cancer. 2005;5(1):11-20.
-
(2005)
Nat Rev Cancer.
, vol.5
, Issue.1
, pp. 11-20
-
-
Hitzler, J.K.1
Zipursky, A.2
-
38
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell PC. The clonal evolution of tumor cell populations. Science. 1976;194(4260):23-28.
-
(1976)
Science.
, vol.194
, Issue.4260
, pp. 23-28
-
-
Nowell, P.C.1
-
39
-
-
84865537739
-
High frequency of copy number alterations in myeloid leukaemia of Down syndrome
-
Blink M, van den Heuvel-Eibrink MM, Aalbers AM, et al. High frequency of copy number alterations in myeloid leukaemia of Down syndrome. Br J Haematol. 2012;158(6):800-803.
-
(2012)
Br J Haematol.
, vol.158
, Issue.6
, pp. 800-803
-
-
Blink, M.1
Van Den Heuvel-Eibrink, M.M.2
Aalbers, A.M.3
-
40
-
-
0033991491
-
The role of p53 in megakaryocyte differentiation and the megakaryocytic leukemias of Down syndrome
-
Malkin D, Brown EJ, Zipursky A. The role of p53 in megakaryocyte differentiation and the megakaryocytic leukemias of Down syndrome. Cancer Genet Cytogenet. 2000;116(1):1-5.
-
(2000)
Cancer Genet Cytogenet.
, vol.116
, Issue.1
, pp. 1-5
-
-
Malkin, D.1
Brown, E.J.2
Zipursky, A.3
-
41
-
-
34547946210
-
Analysis of JAK3, JAK2, and C-MPL mutations in transient myeloproliferative disorder and myeloid leukemia of Down syndrome blasts in children with Down syndrome
-
Norton A, Fisher C, Liu H, et al. Analysis of JAK3, JAK2, and C-MPL mutations in transient myeloproliferative disorder and myeloid leukemia of Down syndrome blasts in children with Down syndrome. Blood. 2007;110(3):1077-1079.
-
(2007)
Blood
, vol.110
, Issue.3
, pp. 1077-1079
-
-
Norton, A.1
Fisher, C.2
Liu, H.3
-
42
-
-
54049107944
-
Activating mutations in human acute megakaryoblastic leukemia
-
Malinge S, Ragu C, Della-Valle V, et al. Activating mutations in human acute megakaryoblastic leukemia. Blood. 2008;112(10):4220-4226.
-
(2008)
Blood
, vol.112
, Issue.10
, pp. 4220-4226
-
-
Malinge, S.1
Ragu, C.2
Della-Valle, V.3
|