Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

Nature Genetics

Volumn 32, Issue 1, 2002, Pages 148-152

  Wechsler, Joshua ^a   Greene, Marianne ^a   McDevitt, Michael A ^b   Anastasi, John ^a   Karp, Judith E ^c   Le Beau, Michelle M ^a   Crispino, John D ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; TRANSCRIPTION FACTOR GATA 1;

ACUTE LEUKEMIA; ACUTE MEGAKARYOCYTIC LEUKEMIA; ARTICLE; CANCER RISK; CONTROLLED STUDY; DNA SEQUENCE; DOWN SYNDROME; GENE MUTATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKEMOGENESIS; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM;

CARRIER PROTEINS; CHILD, PRESCHOOL; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DNA; DNA-BINDING PROTEINS; DOWN SYNDROME; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; FEMALE; GATA1 TRANSCRIPTION FACTOR; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFANT; LEUKEMIA, MEGAKARYOCYTIC, ACUTE; MALE; MUTATION; NUCLEAR PROTEINS; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0036727413     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng955     Document Type: Article

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