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Volumn 111, Issue 2, 2008, Pages 767-775

Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome

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TRANSCRIPTION FACTOR RUNX1;

EID: 38349119730     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2007-04-085670     Document Type: Article
Times cited : (91)

References (41)
  • 1
    • 0027163065 scopus 로고
    • Hematologic abnormalities in children with Down syndrome
    • Roizen NJ, Amarose AP. Hematologic abnormalities in children with Down syndrome. Am J Med Genet. 1993;46:510-512.
    • (1993) Am J Med Genet , vol.46 , pp. 510-512
    • Roizen, N.J.1    Amarose, A.P.2
  • 2
    • 0029987146 scopus 로고    scopus 로고
    • Peripheral blood cell counts in infants with Down's syndrome
    • Kivivuori SM, Rajantie J, Siimes MA. Peripheral blood cell counts in infants with Down's syndrome. Clin Genet. 1996;49:15-19.
    • (1996) Clin Genet , vol.49 , pp. 15-19
    • Kivivuori, S.M.1    Rajantie, J.2    Siimes, M.A.3
  • 3
    • 0942287758 scopus 로고    scopus 로고
    • Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome
    • Gurbuxani S, Vyas P, Crispino JD. Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome. Blood. 2004;103:399-406.
    • (2004) Blood , vol.103 , pp. 399-406
    • Gurbuxani, S.1    Vyas, P.2    Crispino, J.D.3
  • 4
    • 0037906527 scopus 로고    scopus 로고
    • Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder
    • Groet J, McElwaine S, Spinelli M, et al. Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder. Lancet. 2003;361:1617-1620.
    • (2003) Lancet , vol.361 , pp. 1617-1620
    • Groet, J.1    McElwaine, S.2    Spinelli, M.3
  • 6
    • 0042243593 scopus 로고    scopus 로고
    • Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21
    • Rainis L, Bercovich D, Strehl S, et al. Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21. Blood. 2003;102:981-986.
    • (2003) Blood , vol.102 , pp. 981-986
    • Rainis, L.1    Bercovich, D.2    Strehl, S.3
  • 7
    • 0141889275 scopus 로고    scopus 로고
    • Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome
    • Xu G, Nagano M, Kanezaki R, et al. Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome. Blood. 2003;102:2960-2968.
    • (2003) Blood , vol.102 , pp. 2960-2968
    • Xu, G.1    Nagano, M.2    Kanezaki, R.3
  • 8
    • 0036727413 scopus 로고    scopus 로고
    • Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome
    • Wechsler J, Greene M, McDevitt MA, et al. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nat Genet. 2002;32:148-152.
    • (2002) Nat Genet , vol.32 , pp. 148-152
    • Wechsler, J.1    Greene, M.2    McDevitt, M.A.3
  • 9
    • 0033780541 scopus 로고    scopus 로고
    • The management of neoplastic disorders of haematopoiesis in children with Down's syndrome
    • Lange B. The management of neoplastic disorders of haematopoiesis in children with Down's syndrome. Br J Haematol. 2000;110:512-524.
    • (2000) Br J Haematol , vol.110 , pp. 512-524
    • Lange, B.1
  • 10
    • 0029558618 scopus 로고
    • Alternative translation initiation site usage results in two functionally distinct forms of the GATA-1 transcription factor
    • Calligaris R, Bottardi S, Cogoi S, Apezteguia I, Santoro C. Alternative translation initiation site usage results in two functionally distinct forms of the GATA-1 transcription factor. Proc Natl Acad Sci U S A. 1995;92:11598-11602.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 11598-11602
    • Calligaris, R.1    Bottardi, S.2    Cogoi, S.3    Apezteguia, I.4    Santoro, C.5
  • 11
    • 33749021334 scopus 로고    scopus 로고
    • A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia
    • Majewski IJ, Metcalf D, Mielke LA, et al. A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia. Proc Natl Acad Sci U S A. 2006;103:14146-14151.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 14146-14151
    • Majewski, I.J.1    Metcalf, D.2    Mielke, L.A.3
  • 12
    • 20044381309 scopus 로고    scopus 로고
    • Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1
    • Li Z, Godinho FJ, Klusmann JH, Garriga-Canut M, Yu C, Orkin SH. Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1. Nat Genet. 2005;37:613-619.
    • (2005) Nat Genet , vol.37 , pp. 613-619
    • Li, Z.1    Godinho, F.J.2    Klusmann, J.H.3    Garriga-Canut, M.4    Yu, C.5    Orkin, S.H.6
  • 13
    • 33745579586 scopus 로고    scopus 로고
    • An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis
    • Hollanda LM, Lima CS, Cunha AF, et al. An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis. Nat Genet. 2006;38:807-812.
    • (2006) Nat Genet , vol.38 , pp. 807-812
    • Hollanda, L.M.1    Lima, C.S.2    Cunha, A.F.3
  • 14
    • 7444231620 scopus 로고    scopus 로고
    • A chromosome 21 critical region does not cause specific Down syndrome phenotypes
    • Olson LE, Richtsmeier JT, Leszl J, Reeves RH. A chromosome 21 critical region does not cause specific Down syndrome phenotypes. Science. 2004;306:687-690.
    • (2004) Science , vol.306 , pp. 687-690
    • Olson, L.E.1    Richtsmeier, J.T.2    Leszl, J.3    Reeves, R.H.4
  • 15
    • 0030061554 scopus 로고    scopus 로고
    • AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
    • Okuda T, van Deursen J, Hiebert SW, Grosveld G, Downing JR. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell. 1996;84:321-330.
    • (1996) Cell , vol.84 , pp. 321-330
    • Okuda, T.1    van Deursen, J.2    Hiebert, S.W.3    Grosveld, G.4    Downing, J.R.5
  • 16
    • 0032822953 scopus 로고    scopus 로고
    • The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: Biology and clinical significance
    • Downing JR. The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: biology and clinical significance. Br J Haematol. 1999;106:296-308.
    • (1999) Br J Haematol , vol.106 , pp. 296-308
    • Downing, J.R.1
  • 17
    • 0029019659 scopus 로고
    • AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia
    • Nucifora G, Rowley JD. AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia. Blood. 1995;86:1-14.
    • (1995) Blood , vol.86 , pp. 1-14
    • Nucifora, G.1    Rowley, J.D.2
  • 18
    • 0032830638 scopus 로고    scopus 로고
    • Haplo-insufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
    • Song WJ, Sullivan MG, Legare RD, et al. Haplo-insufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia. Nat Genet. 1999;23:166-175.
    • (1999) Nat Genet , vol.23 , pp. 166-175
    • Song, W.J.1    Sullivan, M.G.2    Legare, R.D.3
  • 19
    • 24744468832 scopus 로고    scopus 로고
    • The protooncogene ERG in megakaryoblastic leukemias
    • Rainis L, Toki T, Pimanda JE, et al. The protooncogene ERG in megakaryoblastic leukemias. Cancer Res. 2005;65:7596-7602.
    • (2005) Cancer Res , vol.65 , pp. 7596-7602
    • Rainis, L.1    Toki, T.2    Pimanda, J.E.3
  • 20
    • 0033980511 scopus 로고    scopus 로고
    • Parallels of craniofacial maldevelopment in Down syndrome and Ts65Dn mice
    • Richtsmeier JT, Baxter LL, Reeves RH. Parallels of craniofacial maldevelopment in Down syndrome and Ts65Dn mice. Dev Dyn. 2000;217:137-145.
    • (2000) Dev Dyn , vol.217 , pp. 137-145
    • Richtsmeier, J.T.1    Baxter, L.L.2    Reeves, R.H.3
  • 22
    • 0029114706 scopus 로고
    • A mouse model for Down syndrome exhibits learning and behaviour deficits
    • Reeves RH, Irving NG, Moran TH, et al. A mouse model for Down syndrome exhibits learning and behaviour deficits. Nat Genet. 1995;11:177-184.
    • (1995) Nat Genet , vol.11 , pp. 177-184
    • Reeves, R.H.1    Irving, N.G.2    Moran, T.H.3
  • 23
    • 0027719985 scopus 로고
    • Segmental trisomy as a mouse model for Down syndrome
    • Davisson MT, Schmidt C, Reeves RH, et al. Segmental trisomy as a mouse model for Down syndrome. Prog Clin Biol Res. 1993;384:117-133.
    • (1993) Prog Clin Biol Res , vol.384 , pp. 117-133
    • Davisson, M.T.1    Schmidt, C.2    Reeves, R.H.3
  • 24
    • 33749576059 scopus 로고    scopus 로고
    • Postnatal lethality and cardiac anomalies in the Ts65Dn Down syndrome mouse model
    • Moore CS. Postnatal lethality and cardiac anomalies in the Ts65Dn Down syndrome mouse model. Mamm Genome. 2006;17:1005-1012.
    • (2006) Mamm Genome , vol.17 , pp. 1005-1012
    • Moore, C.S.1
  • 25
    • 33748191708 scopus 로고    scopus 로고
    • The growth capacity of bone marrow CD34 positive cells in culture is drastically reduced in a murine model of Down syndrome
    • Jablonska B, Ford D, Trisler D, Pessac B. The growth capacity of bone marrow CD34 positive cells in culture is drastically reduced in a murine model of Down syndrome. C R Biol. 2006;329:726-732.
    • (2006) C R Biol , vol.329 , pp. 726-732
    • Jablonska, B.1    Ford, D.2    Trisler, D.3    Pessac, B.4
  • 26
    • 33845436745 scopus 로고    scopus 로고
    • The myeloproliferative disorders
    • Campbell PJ, Green AR. The myeloproliferative disorders. N Engl J Med. 2006;355:2452-2466.
    • (2006) N Engl J Med , vol.355 , pp. 2452-2466
    • Campbell, P.J.1    Green, A.R.2
  • 28
    • 0036660179 scopus 로고    scopus 로고
    • Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice
    • Kogan SC, Ward JM, Anver MR, et al. Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice. Blood. 2002;100:238-245.
    • (2002) Blood , vol.100 , pp. 238-245
    • Kogan, S.C.1    Ward, J.M.2    Anver, M.R.3
  • 29
    • 33646546386 scopus 로고    scopus 로고
    • The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation
    • Jamieson CH, Gotlib J, Durocher JA, et al. The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation. Proc Natl Acad Sci U S A. 2006;103:6224-6229.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 6224-6229
    • Jamieson, C.H.1    Gotlib, J.2    Durocher, J.A.3
  • 30
    • 3943088431 scopus 로고    scopus 로고
    • Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
    • Jamieson CH, Ailles LE, Dylla SJ, et al. Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med. 2004;351:657-667.
    • (2004) N Engl J Med , vol.351 , pp. 657-667
    • Jamieson, C.H.1    Ailles, L.E.2    Dylla, S.J.3
  • 31
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter EJ, Scott LM, Campbell PJ, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet. 2005;365:1054-1061.
    • (2005) Lancet , vol.365 , pp. 1054-1061
    • Baxter, E.J.1    Scott, L.M.2    Campbell, P.J.3
  • 32
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couedic JP, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature. 2005;434:1144-1148.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3
  • 33
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, Wadleigh M, Cools J, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 2005;7:387-397.
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.L.1    Wadleigh, M.2    Cools, J.3
  • 34
    • 17644424955 scopus 로고    scopus 로고
    • A gain-of-function mutation of JAK2 in myeloproliferative disorders
    • Kralovics R, Passamonti F, Buser AS, et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med. 2005;352:1779-1790.
    • (2005) N Engl J Med , vol.352 , pp. 1779-1790
    • Kralovics, R.1    Passamonti, F.2    Buser, A.S.3
  • 35
    • 20744460045 scopus 로고    scopus 로고
    • Identification of an acquired JAK2 mutation in polycythemia vera
    • Zhao R, Xing S, Li Z, et al. Identification of an acquired JAK2 mutation in polycythemia vera. J Biol Chem. 2005;280:22788-22792.
    • (2005) J Biol Chem , vol.280 , pp. 22788-22792
    • Zhao, R.1    Xing, S.2    Li, Z.3
  • 36
    • 33745713168 scopus 로고    scopus 로고
    • Activating alleles of JAK3 in acute megakaryoblastic leukemia
    • Walters DK, Mercher T, Gu TL, et al. Activating alleles of JAK3 in acute megakaryoblastic leukemia. Cancer Cell. 2006;10:65-75.
    • (2006) Cancer Cell , vol.10 , pp. 65-75
    • Walters, D.K.1    Mercher, T.2    Gu, T.L.3
  • 37
    • 0025350375 scopus 로고
    • The Philadelphia chromosome translocation: A paradigm for understanding leukemia
    • Rowley JD. The Philadelphia chromosome translocation: a paradigm for understanding leukemia. Cancer. 1990;65:2178-2184.
    • (1990) Cancer , vol.65 , pp. 2178-2184
    • Rowley, J.D.1
  • 38
    • 33644759290 scopus 로고    scopus 로고
    • Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling
    • Bourquin JP, Subramanian A, Langebrake C, et al. Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling. Proc Natl Acad Sci U S A. 2006;103:3339-3344.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 3339-3344
    • Bourquin, J.P.1    Subramanian, A.2    Langebrake, C.3
  • 39
    • 28844486209 scopus 로고    scopus 로고
    • Intrinsic abnormalities of lymphocyte counts in children with down syndrome
    • de Hingh YC, van der Vossen PW, Gemen EF, et al. Intrinsic abnormalities of lymphocyte counts in children with down syndrome. J Pediatr. 2005;147:744-747.
    • (2005) J Pediatr , vol.147 , pp. 744-747
    • de Hingh, Y.C.1    van der Vossen, P.W.2    Gemen, E.F.3
  • 40
    • 38349185425 scopus 로고    scopus 로고
    • A genome-wide retroviral insertional mutagenesis screen for genes cooperating with truncated, oncogenic GATA1s. Blood
    • Li Z, Klusmann J-H, Godinho FJ, Lee H-W, Reinhardt D, Orkin SH. A genome-wide retroviral insertional mutagenesis screen for genes cooperating with truncated, oncogenic GATA1s. Blood. 2005;106:2990 [abstract].
    • (2005) 2990 [abstract] , vol.106
    • Li, Z.1    Klusmann, J.-H.2    Godinho, F.J.3    Lee, H.-W.4    Reinhardt, D.5    Orkin, S.H.6
  • 41
    • 4444347949 scopus 로고    scopus 로고
    • Prenatal origin of GATA1 mutations may be an initiating step in the development of megakaryocytic leukemia in Down syndrome
    • Taub JW, Mundschau G, Ge Y, et al. Prenatal origin of GATA1 mutations may be an initiating step in the development of megakaryocytic leukemia in Down syndrome. Blood. 2004;104:1588-1589.
    • (2004) Blood , vol.104 , pp. 1588-1589
    • Taub, J.W.1    Mundschau, G.2    Ge, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.