Identification of hepatic niche harboring human acute lymphoblastic leukemic cells via the SDF-1/CXCR4 axis

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Kato, Itaru ^a,b   Niwa, Akira ^a,b   Heike, Toshio ^b   Fujino, Hisanori ^b   Saito, Megumu K ^a,b   Umeda, Katsutsugu ^c   Hiramatsu, Hidefumi ^b   Ito, Mamoru ^d   Morita, Makiko ^b   Nishinaka, Yoko ^b   Adachi, Souichi ^b   Ishikawa, Fumihiko ^e   Nakahata, Tatsutoshi ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^d CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS   (Japan)

^e Institute of Physical and Chemical Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CYTARABINE; PLERIXAFOR; STROMAL CELL DERIVED FACTOR 1;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT; CELL INFILTRATION; CELL INVASION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CHILD; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; EPITHELIUM CELL; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACELLULAR SIGNALING; LEUKEMIA CELL; LIVER CELL; LIVER FUNCTION; LIVER METASTASIS; MALE; MOUSE; NONHUMAN; OVERALL SURVIVAL; PRESCHOOL CHILD; PROTEIN FUNCTION; PROTEIN TARGETING; SCHOOL CHILD; TUMOR XENOGRAFT;

ANIMALS; ANTI-HIV AGENTS; BLOTTING, WESTERN; BONE MARROW; CELL ADHESION; CELL CYCLE; CELL MOVEMENT; CELL PROLIFERATION; CHEMOKINE CXCL12; CHILD; CHILD, PRESCHOOL; FEMALE; FLOW CYTOMETRY; HEPATOCYTES; HETEROCYCLIC COMPOUNDS; HUMANS; INFANT; LIVER; MALE; MICE; MICE, INBRED NOD; MICE, SCID; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECEPTORS, CXCR4; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

MUS;

EID: 84858225214     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027042     Document Type: Article

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