메뉴 건너뛰기




Volumn 126, Issue 3, 2013, Pages 382-388

P2X7 receptor-induced death of motor neurons by a peroxynitrite/FAS- dependent pathway

Author keywords

adenosine; amyotrophic lateral sclerosis; CD95; motor neuron disease; nitric oxide; purinergic

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; 3' O (4 BENZOYLBENZOYL)ADENOSINE TRIPHOSPHATE; ADENOSINE; ADENOSINE RECEPTOR; ADENOSINE TRIPHOSPHATE; CASPASE; FAS ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE P38; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PEROXYNITRITE; PURINERGIC P2X7 RECEPTOR;

EID: 84880573457     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12286     Document Type: Article
Times cited : (49)

References (46)
  • 1
    • 84868019293 scopus 로고    scopus 로고
    • FasL-triggered death of Jurkat cells requires caspase 8-induced, ATP-dependent cross-talk between Fas and the purinergic receptor P2X(7)
    • Aguirre A., Shoji K. F., Saez J. C., Henriquez M., and, Quest A. F., (2013) FasL-triggered death of Jurkat cells requires caspase 8-induced, ATP-dependent cross-talk between Fas and the purinergic receptor P2X(7). J. Cell. Physiol. 228, 485-493.
    • (2013) J. Cell. Physiol. , vol.228 , pp. 485-493
    • Aguirre, A.1    Shoji, K.F.2    Saez, J.C.3    Henriquez, M.4    Quest, A.F.5
  • 2
    • 58149175921 scopus 로고    scopus 로고
    • Membrane compartments and purinergic signalling: P2X receptors in neurodegenerative and neuroinflammatory events
    • Apolloni S., Montilli C., Finocchi P., and, Amadio S., (2009) Membrane compartments and purinergic signalling: P2X receptors in neurodegenerative and neuroinflammatory events. FEBS J. 276, 354-364.
    • (2009) FEBS J. , vol.276 , pp. 354-364
    • Apolloni, S.1    Montilli, C.2    Finocchi, P.3    Amadio, S.4
  • 3
    • 46449134214 scopus 로고    scopus 로고
    • Purinergic signalling and disorders of the central nervous system
    • Burnstock G., (2008) Purinergic signalling and disorders of the central nervous system. Nat. Rev. Drug Discov. 7, 575-590.
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 575-590
    • Burnstock, G.1
  • 4
    • 37349068139 scopus 로고    scopus 로고
    • Strong P2X4 purinergic receptor-like immunoreactivity is selectively associated with degenerating neurons in transgenic rodent models of amyotrophic lateral sclerosis
    • Casanovas A., Hernandez S., Tarabal O., Rossello J., and, Esquerda J. E., (2008) Strong P2X4 purinergic receptor-like immunoreactivity is selectively associated with degenerating neurons in transgenic rodent models of amyotrophic lateral sclerosis. J. Comp. Neurol. 506, 75-92.
    • (2008) J. Comp. Neurol. , vol.506 , pp. 75-92
    • Casanovas, A.1    Hernandez, S.2    Tarabal, O.3    Rossello, J.4    Esquerda, J.E.5
  • 5
    • 27744542561 scopus 로고    scopus 로고
    • FAS deficiency reduces apoptosis, spares axons and improves function after spinal cord injury
    • Casha S., Yu W. R., and, Fehlings M. G., (2005) FAS deficiency reduces apoptosis, spares axons and improves function after spinal cord injury. Exp. Neurol. 196, 390-400.
    • (2005) Exp. Neurol. , vol.196 , pp. 390-400
    • Casha, S.1    Yu, W.R.2    Fehlings, M.G.3
  • 7
    • 11144354396 scopus 로고    scopus 로고
    • Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury
    • Demjen D., Klussmann S., Kleber S., et al,. (2004) Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury. Nat. Med. 10, 389-395.
    • (2004) Nat. Med. , vol.10 , pp. 389-395
    • Demjen, D.1    Klussmann, S.2    Kleber, S.3
  • 9
    • 70350339068 scopus 로고    scopus 로고
    • Mammalian P2X7 receptor pharmacology: Comparison of recombinant mouse, rat and human P2X7 receptors
    • Donnelly-Roberts D. L., Namovic M. T., Han P., and, Jarvis M. F., (2009) Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors. Br. J. Pharmacol. 157, 1203-1214.
    • (2009) Br. J. Pharmacol. , vol.157 , pp. 1203-1214
    • Donnelly-Roberts, D.L.1    Namovic, M.T.2    Han, P.3    Jarvis, M.F.4
  • 10
    • 0031773432 scopus 로고    scopus 로고
    • Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture
    • Estevez A. G., Spear N., Manuel S. M., Barbeito L., Radi R., and, Beckman J. S., (1998) Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture. Prog. Brain Res. 118, 269-280.
    • (1998) Prog. Brain Res. , vol.118 , pp. 269-280
    • Estevez, A.G.1    Spear, N.2    Manuel, S.M.3    Barbeito, L.4    Radi, R.5    Beckman, J.S.6
  • 13
    • 77953198913 scopus 로고    scopus 로고
    • Extracellular ATP and the P2X7 receptor in astrocyte-mediated motor neuron death: Implications for amyotrophic lateral sclerosis
    • Gandelman M., Peluffo H., Beckman J. S., Cassina P., and, Barbeito L., (2010) Extracellular ATP and the P2X7 receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis. J. Neuroinflammation 7, 33.
    • (2010) J. Neuroinflammation , vol.7 , pp. 33
    • Gandelman, M.1    Peluffo, H.2    Beckman, J.S.3    Cassina, P.4    Barbeito, L.5
  • 14
    • 77953722078 scopus 로고    scopus 로고
    • Selective adenosine A(2a) receptor agonists reduce the apoptosis in an experimental model of spinal cord trauma
    • Genovese T., Melani A., Esposito E., et al,. (2010) Selective adenosine A(2a) receptor agonists reduce the apoptosis in an experimental model of spinal cord trauma. J. Biol. Regul. Homeost. Agents 24, 73-86.
    • (2010) J. Biol. Regul. Homeost. Agents , vol.24 , pp. 73-86
    • Genovese, T.1    Melani, A.2    Esposito, E.3
  • 15
    • 0028823098 scopus 로고
    • The antinociceptive effect of 1-(2-trifluoromethylphenyl) imidazole (TRIM), a potent inhibitor of neuronal nitric oxide synthase in vitro, in the mouse
    • Handy R. L., Wallace P., Gaffen Z. A., Whitehead K. J., and, Moore P.K., (1995) The antinociceptive effect of 1-(2-trifluoromethylphenyl) imidazole (TRIM), a potent inhibitor of neuronal nitric oxide synthase in vitro, in the mouse. Br. J. Pharmacol. 116, 2349-2350.
    • (1995) Br. J. Pharmacol. , vol.116 , pp. 2349-2350
    • Handy, R.L.1    Wallace, P.2    Gaffen, Z.A.3    Whitehead, K.J.4    Moore, P.K.5
  • 17
    • 36749075156 scopus 로고    scopus 로고
    • P2X(7) receptor-mediated reactive oxygen and nitrogen species formation: From receptor to generators
    • Hewinson J., and, Mackenzie A. B., (2007) P2X(7) receptor-mediated reactive oxygen and nitrogen species formation: from receptor to generators. Biochem. Soc. Trans. 35, 1168-1170.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 1168-1170
    • Hewinson, J.1    Mackenzie, A.B.2
  • 18
    • 33644770260 scopus 로고    scopus 로고
    • Adenosine receptors as therapeutic targets
    • Jacobson K. A., and, Gao Z. G., (2006) Adenosine receptors as therapeutic targets. Nat. Rev. Drug Discov. 5, 247-264.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 247-264
    • Jacobson, K.A.1    Gao, Z.G.2
  • 19
    • 38049110607 scopus 로고    scopus 로고
    • Extracellular ATP mediates necrotic cell swelling in SN4741 dopaminergic neurons through P2X7 receptors
    • Jun D. J., Kim J., Jung S. Y., et al,. (2007) Extracellular ATP mediates necrotic cell swelling in SN4741 dopaminergic neurons through P2X7 receptors. J. Biol. Chem. 282, 37350-37358.
    • (2007) J. Biol. Chem. , vol.282 , pp. 37350-37358
    • Jun, D.J.1    Kim, J.2    Jung, S.Y.3
  • 20
    • 18744396365 scopus 로고    scopus 로고
    • P2X and P2Y receptors as possible targets of therapeutic manipulations in CNS illnesses
    • Koles L., Furst S., and, Illes P., (2005) P2X and P2Y receptors as possible targets of therapeutic manipulations in CNS illnesses. Drug News Perspect. 18, 85-101.
    • (2005) Drug News Perspect. , vol.18 , pp. 85-101
    • Koles, L.1    Furst, S.2    Illes, P.3
  • 21
    • 34547764229 scopus 로고    scopus 로고
    • Fas small interfering RNA reduces motoneuron death in amyotrophic lateral sclerosis mice
    • Locatelli F., Corti S., Papadimitriou D., et al,. (2007) Fas small interfering RNA reduces motoneuron death in amyotrophic lateral sclerosis mice. Ann. Neurol. 62, 81-92.
    • (2007) Ann. Neurol. , vol.62 , pp. 81-92
    • Locatelli, F.1    Corti, S.2    Papadimitriou, D.3
  • 22
    • 21844470751 scopus 로고    scopus 로고
    • Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation
    • Martin L. J., Chen K., and, Liu Z., (2005) Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation. J. Neurosci. 25, 6449-6459.
    • (2005) J. Neurosci. , vol.25 , pp. 6449-6459
    • Martin, L.J.1    Chen, K.2    Liu, Z.3
  • 24
    • 34548398189 scopus 로고    scopus 로고
    • P2X(7) receptor blockade prevents ATP excitotoxicity in oligodendrocytes and ameliorates experimental autoimmune encephalomyelitis
    • Matute C., Torre I., Perez-Cerda F., et al,. (2007) P2X(7) receptor blockade prevents ATP excitotoxicity in oligodendrocytes and ameliorates experimental autoimmune encephalomyelitis. J. Neurosci. 27, 9525-9533.
    • (2007) J. Neurosci. , vol.27 , pp. 9525-9533
    • Matute, C.1    Torre, I.2    Perez-Cerda, F.3
  • 25
    • 24144447012 scopus 로고    scopus 로고
    • ATP extracellular concentrations are increased in the rat striatum during in vivo ischemia
    • Melani A., Turchi D., Vannucchi M. G., Cipriani S., Gianfriddo M., and, Pedata F., (2005) ATP extracellular concentrations are increased in the rat striatum during in vivo ischemia. Neurochem. Int. 47, 442-448.
    • (2005) Neurochem. Int. , vol.47 , pp. 442-448
    • Melani, A.1    Turchi, D.2    Vannucchi, M.G.3    Cipriani, S.4    Gianfriddo, M.5    Pedata, F.6
  • 28
    • 34447633192 scopus 로고    scopus 로고
    • Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis
    • Pehar M., Vargas M. R., Robinson K. M., Cassina P., Diaz-Amarilla P. J., Hagen T. M., Radi R., Barbeito L., and, Beckman J. S., (2007) Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis. J. Neurosci. 27, 7777-7785.
    • (2007) J. Neurosci. , vol.27 , pp. 7777-7785
    • Pehar, M.1    Vargas, M.R.2    Robinson, K.M.3    Cassina, P.4    Diaz-Amarilla, P.J.5    Hagen, T.M.6    Radi, R.7    Barbeito, L.8    Beckman, J.S.9
  • 29
    • 68149157440 scopus 로고    scopus 로고
    • Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury
    • Peng W., Cotrina M. L., Han X., et al,. (2009) Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury. Proc. Natl Acad. Sci. USA 106, 12489-12493.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 12489-12493
    • Peng, W.1    Cotrina, M.L.2    Han, X.3
  • 30
    • 0027212086 scopus 로고
    • Adenosine 5′-triphosphate release from the normoxic and hypoxic in vivo rat cerebral cortex
    • Phillis J. W., O'Regan M. H., and, Perkins L. M., (1993) Adenosine 5′-triphosphate release from the normoxic and hypoxic in vivo rat cerebral cortex. Neurosci. Lett. 151, 94-96.
    • (1993) Neurosci. Lett. , vol.151 , pp. 94-96
    • Phillis, J.W.1    O'Regan, M.H.2    Perkins, L.M.3
  • 31
    • 45849102043 scopus 로고    scopus 로고
    • ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way
    • Piccini A., Carta S., Tassi S., Lasiglie D., Fossati G., and, Rubartelli A., (2008) ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way. Proc. Natl Acad. Sci. USA 105, 8067-8072.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 8067-8072
    • Piccini, A.1    Carta, S.2    Tassi, S.3    Lasiglie, D.4    Fossati, G.5    Rubartelli, A.6
  • 32
    • 0033615957 scopus 로고    scopus 로고
    • Programmed cell death of embryonic motoneurons triggered through the Fas death receptor
    • Raoul C., Henderson C. E., and, Pettmann B., (1999) Programmed cell death of embryonic motoneurons triggered through the Fas death receptor. J. Cell Biol. 147, 1049-1062.
    • (1999) J. Cell Biol. , vol.147 , pp. 1049-1062
    • Raoul, C.1    Henderson, C.E.2    Pettmann, B.3
  • 34
  • 35
    • 1042290474 scopus 로고    scopus 로고
    • Triuret: A novel product of peroxynitrite-mediated oxidation of urate
    • Robinson K. M., Morre J. T., and, Beckman J. S., (2004) Triuret: a novel product of peroxynitrite-mediated oxidation of urate. Arch. Biochem. Biophys. 423, 213-217.
    • (2004) Arch. Biochem. Biophys. , vol.423 , pp. 213-217
    • Robinson, K.M.1    Morre, J.T.2    Beckman, J.S.3
  • 36
    • 56749085777 scopus 로고    scopus 로고
    • Block of purinergic P2X(7) receptor is neuroprotective in an animal model of Alzheimer's disease
    • Ryu J. K., and, McLarnon J. G., (2008) Block of purinergic P2X(7) receptor is neuroprotective in an animal model of Alzheimer's disease. NeuroReport 19, 1715-1719.
    • (2008) NeuroReport , vol.19 , pp. 1715-1719
    • Ryu, J.K.1    McLarnon, J.G.2
  • 37
    • 77958557012 scopus 로고    scopus 로고
    • Cu, Zn-superoxide dismutase increases toxicity of mutant and zinc-deficient superoxide dismutase by enhancing protein stability
    • Sahawneh M. A., Ricart K. C., Roberts B. R., et al,. (2010) Cu, Zn-superoxide dismutase increases toxicity of mutant and zinc-deficient superoxide dismutase by enhancing protein stability. J. Biol. Chem. 285, 33885-33897.
    • (2010) J. Biol. Chem. , vol.285 , pp. 33885-33897
    • Sahawneh, M.A.1    Ricart, K.C.2    Roberts, B.R.3
  • 38
    • 0032557863 scopus 로고    scopus 로고
    • Delayed selective motor neuron death and fas antigen induction after spinal cord ischemia in rabbits
    • Sakurai M., Hayashi T., Abe K., Sadahiro M., and, Tabayashi K., (1998) Delayed selective motor neuron death and fas antigen induction after spinal cord ischemia in rabbits. Brain Res. 797, 23-28.
    • (1998) Brain Res. , vol.797 , pp. 23-28
    • Sakurai, M.1    Hayashi, T.2    Abe, K.3    Sadahiro, M.4    Tabayashi, K.5
  • 39
    • 0033572573 scopus 로고    scopus 로고
    • Uric acid oxidation by peroxynitrite: Multiple reactions, free radical formation, and amplification of lipid oxidation
    • Santos C. X., Anjos E. I., and, Augusto O., (1999) Uric acid oxidation by peroxynitrite: multiple reactions, free radical formation, and amplification of lipid oxidation. Arch. Biochem. Biophys. 372, 285-294.
    • (1999) Arch. Biochem. Biophys. , vol.372 , pp. 285-294
    • Santos, C.X.1    Anjos, E.I.2    Augusto, O.3
  • 40
    • 83755181392 scopus 로고    scopus 로고
    • Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model
    • Soon C. P., Donnelly P. S., Turner B. J., et al,. (2011) Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model. J. Biol. Chem. 286, 44035-44044.
    • (2011) J. Biol. Chem. , vol.286 , pp. 44035-44044
    • Soon, C.P.1    Donnelly, P.S.2    Turner, B.J.3
  • 43
    • 4043079197 scopus 로고    scopus 로고
    • P2X7 receptor inhibition improves recovery after spinal cord injury
    • Wang X., Arcuino G., Takano T., et al,. (2004) P2X7 receptor inhibition improves recovery after spinal cord injury. Nat. Med. 10, 821-827.
    • (2004) Nat. Med. , vol.10 , pp. 821-827
    • Wang, X.1    Arcuino, G.2    Takano, T.3
  • 44
    • 36749091754 scopus 로고    scopus 로고
    • Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB
    • Wiese S., Jablonka S., Holtmann B., Orel N., Rajagopal R., Chao M. V., and, Sendtner M., (2007) Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB. Proc. Natl Acad. Sci. USA 104, 17210-17215.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 17210-17215
    • Wiese, S.1    Jablonka, S.2    Holtmann, B.3    Orel, N.4    Rajagopal, R.5    Chao, M.V.6    Sendtner, M.7
  • 45
    • 0037380924 scopus 로고    scopus 로고
    • Iron porphyrin treatment extends survival in a transgenic animal model of amyotrophic lateral sclerosis
    • Wu A. S., Kiaei M., Aguirre N., Crow J. P., Calingasan N. Y., Browne S. E., and, Beal M. F., (2003) Iron porphyrin treatment extends survival in a transgenic animal model of amyotrophic lateral sclerosis. J. Neurochem. 85, 142-150.
    • (2003) J. Neurochem. , vol.85 , pp. 142-150
    • Wu, A.S.1    Kiaei, M.2    Aguirre, N.3    Crow, J.P.4    Calingasan, N.Y.5    Browne, S.E.6    Beal, M.F.7
  • 46
    • 33645224970 scopus 로고    scopus 로고
    • COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord
    • Yiangou Y., Facer P., Durrenberger P., Chessell I. P., Naylor A., Bountra C., Banati R. R., and, Anand P., (2006) COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord. BMC Neurol. 6, 12. Sciences
    • (2006) BMC Neurol. , vol.6 , pp. 12
    • Yiangou, Y.1    Facer, P.2    Durrenberger, P.3    Chessell, I.P.4    Naylor, A.5    Bountra, C.6    Banati, R.R.7    Anand, P.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.