Pancreatic-derived factor (FAM3B), a novel islet cytokine, induces apoptosis of insulin-secreting β-cells

Diabetes

Volumn 52, Issue 9, 2003, Pages 2296-2303

  Cao, Xiaopei ^a   Gao, Zhiyong ^a   Robert, Claudia E ^a   Greene, Scott ^a   Xu, Gang ^a   Xu, Weizhen ^a   Bell, Ewan ^a   Campbell, Don ^a   Zhu, Yuan ^b   Young, Robert ^a   Trucco, Matteo ^a   Markmann, James F ^a   Naji, Ali ^a   Wolf, Bryan A ^a,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b GLAXOSMITHKLINE   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYTOKINE; CYTOKINE FAM3B; GLUCAGON; INSULIN; LIPOCORTIN 5; PANCREATIC DERIVED FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL FUNCTION; CONTROLLED STUDY; DOSE RESPONSE; ELECTRON MICROSCOPY; ENZYME ACTIVATION; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; LANGERHANS CELL; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANNEXIN A5; APOPTOSIS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IN SITU NICK-END LABELING; INSULIN; INSULINOMA; ISLETS OF LANGERHANS; MICE; PANCREATIC NEOPLASMS; RATS; TUMOR CELLS, CULTURED;

EID: 0042320939     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.52.9.2296     Document Type: Article

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