Selection of pfdhfr/pfdhps alleles and declining artesunate/sulphadoxine- pyrimethamine efficacy against Plasmodium falciparum eight years after deployment in eastern Sudan

Malaria Journal

Volumn 12, Issue 1, 2013, Pages

  Gadalla, Nahla B ^a,b   Abdallah, Tajeldin M ^c   Atwal, Sharanjeet ^a   Sutherland, Colin J ^a   Adam, Ishag ^d  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b TROPICAL MEDICINE RESEARCH INSTITUTE   (Sudan)

^c University of Kassala   (Sudan)

^d UNIVERSITY OF KHARTOUM   (Sudan)

Author keywords

Artesunate; Pfcrt; pfdhfr; Pfdhps; Pfmdr1; Plasmodium falciparum; Sudan; Sulphadoxine pyrimethamine

Indexed keywords

ANTIMALARIAL AGENT; ARTESUNATE; ARTESUNATE PLUS SULFADOXINE PLUS PYRIMETHAMINE; PYRIMETHAMINE PLUS SULFADOXINE; UNCLASSIFIED DRUG;

ADULT; ALLELE; ARTICLE; BLOOD SMEAR; CLINICAL PROTOCOL; CODON; DISEASE TRANSMISSION; FEMALE; FOLLOW UP; GENOTYPE; HUMAN; INTENTION TO TREAT ANALYSIS; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; MICROSCOPY; POLYMERASE CHAIN REACTION; SUDAN;

ADOLESCENT; ADULT; AGED; ARTEMISININS; CHILD; CHILD, PRESCHOOL; DNA, PROTOZOAN; DRUG RESISTANCE; FEMALE; GENE DOSAGE; GENE FREQUENCY; HUMANS; MALARIA, FALCIPARUM; MALE; MIDDLE AGED; MUTANT PROTEINS; PLASMODIUM FALCIPARUM; PREVALENCE; PROTOZOAN PROTEINS; PYRIMETHAMINE; REAL-TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SUDAN; SULFADOXINE; YOUNG ADULT;

EID: 84880335168     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-12-255     Document Type: Article

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