메뉴 건너뛰기




Volumn 67, Issue 3, 2002, Pages 225-229

Pyrimethamine/sulfadoxine combination in the treatment of uncomplicated falciparum malaria: Relation between dihydropteroate synthase/dihydrofolate reductase genotypes, sulfadoxine plasma levels, and treatment outcome

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; FANSIDAR; SULFADOXINE;

EID: 0036748522     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2002.67.225     Document Type: Article
Times cited : (25)

References (27)
  • 1
    • 0030813699 scopus 로고    scopus 로고
    • The efficacy of antimalarial combinations in Africa: A predictive model based on pharmacokinetic and pharmacodynamic analysis
    • Watkins WM, Mberu EK, Winstanley PA, Plowe CV, 1997. The efficacy of antimalarial combinations in Africa: a predictive model based on pharmacokinetic and pharmacodynamic analysis. Parasitol Today 13: 459-464,
    • (1997) Parasitol Today , vol.13 , pp. 459-464
    • Watkins, W.M.1    Mberu, E.K.2    Winstanley, P.A.3    Plowe, C.V.4
  • 2
    • 0027401399 scopus 로고
    • Beyond chloroquine: Implication of drug resistance for evaluating malaria therapy, efficacy and treatment policy in Africa
    • Bloland PB, Lackritz EM, Kezembe PN, Were JB, Campbell CC, 1993. Beyond chloroquine: implication of drug resistance for evaluating malaria therapy, efficacy and treatment policy in Africa. J Infect Dis 167: 932-937.
    • (1993) J Infect Dis , vol.167 , pp. 932-937
    • Bloland, P.B.1    Lackritz, E.M.2    Kezembe, P.N.3    Were, J.B.4    Campbell, C.C.5
  • 3
    • 0027470164 scopus 로고
    • Treatment of falciparum malaria with pyrimethamine/sulfadoxine: Selection pressure for resistance is a function of long elimination half-life
    • Watkins WM, Mosobo M, 1993. Treatment of falciparum malaria with pyrimethamine/sulfadoxine: selection pressure for resistance is a function of long elimination half-life. Trans R Soc Trop Med Hyg 87: 75-78.
    • (1993) Trans R Soc Trop Med Hyg , vol.87 , pp. 75-78
    • Watkins, W.M.1    Mosobo, M.2
  • 4
    • 0025263958 scopus 로고
    • Amino acids in dihydrofolate reductase gene of Plasmodium falciparum involved in cycloguanil differ from those involved in pyrimethamine resistance
    • Foote S, Galatis P, Cowman A, 1990. Amino acids in dihydrofolate reductase gene of Plasmodium falciparum involved in cycloguanil differ from those involved in pyrimethamine resistance. Proc Natl Acad Sci U S A 87: 3014-3017.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 3014-3017
    • Foote, S.1    Galatis, P.2    Cowman, A.3
  • 5
    • 0028291789 scopus 로고
    • Primary structure and expression of the dihydropteroate synthase gene of Plasmodium falciparum
    • Triglia T, Cowman AF, 1994. Primary structure and expression of the dihydropteroate synthase gene of Plasmodium falciparum. Proc Natl Acad Sci U S A 91: 13994-13999.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 13994-13999
    • Triglia, T.1    Cowman, A.F.2
  • 7
    • 0030801206 scopus 로고    scopus 로고
    • Resistance to antifolate in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthase and dihydrofolate reductase alleles in a large number of field samples of diverse origin
    • Wang P, Lee C-S, Bayoumi R., Djimde A, Doumbo O, Swedberg, G, Dao LD, Mshinda H, Tanner M, Watkins WM, Sims PFG, Hyde JE, 1997. Resistance to antifolate in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthase and dihydrofolate reductase alleles in a large number of field samples of diverse origin. Mol Biochem Parasitol 89: 161-177.
    • (1997) Mol Biochem Parasitol , vol.89 , pp. 161-177
    • Wang, P.1    Lee, C.-S.2    Bayoumi, R.3    Djimde, A.4    Doumbo, O.5    Swedberg, G.6    Dao, L.D.7    Mshinda, H.8    Tanner, M.9    Watkins, W.M.10    Sims, P.F.G.11    Hyde, J.E.12
  • 8
    • 0031029877 scopus 로고    scopus 로고
    • Sulfadoxine resistance in human malaria parasite Plasmodium falciparum is determined by mutations in the dihydropteroate synthase gene and additional factor associated with folate utilization
    • Wang P, Read M, Sims PFG, Hyde JE, 1997. Sulfadoxine resistance in human malaria parasite Plasmodium falciparum is determined by mutations in the dihydropteroate synthase gene and additional factor associated with folate utilization. Mol Microbiol 23: 979-986.
    • (1997) Mol Microbiol , vol.23 , pp. 979-986
    • Wang, P.1    Read, M.2    Sims, P.F.G.3    Hyde, J.E.4
  • 10
    • 0033022037 scopus 로고    scopus 로고
    • Utilization of exogenous folate in the human malaria parasite Plasmodium falciparum and its critical role in antifolate drug synergy
    • Wang P, Brobey RK, Horii T, Sims PFG, Hyde JE, 1999. Utilization of exogenous folate in the human malaria parasite Plasmodium falciparum and its critical role in antifolate drug synergy. Mol Microbiol 32: 1254-1262.
    • (1999) Mol Microbiol , vol.32 , pp. 1254-1262
    • Wang, P.1    Brobey, R.K.2    Horii, T.3    Sims, P.F.G.4    Hyde, J.E.5
  • 14
    • 0031127302 scopus 로고    scopus 로고
    • Titration of heparinase for the removal of the PCR inhibitory of heparin in DNA samples
    • Taylor A, 1997. Titration of heparinase for the removal of the PCR inhibitory of heparin in DNA samples. Mol Ecol 6: 383-385.
    • (1997) Mol Ecol , vol.6 , pp. 383-385
    • Taylor, A.1
  • 15
    • 0032079104 scopus 로고    scopus 로고
    • Plasmodium falciparum: Detection of polymorphism in the dihydrofolate reductase and dihydropteroate synthase genes by PCR and restriction digestion
    • Duraisingh MT, Curtis J, Warhurst DC, 1998. Plasmodium falciparum: detection of polymorphism in the dihydrofolate reductase and dihydropteroate synthase genes by PCR and restriction digestion. Exp Parasitol 89: 1-8.
    • (1998) Exp Parasitol , vol.89 , pp. 1-8
    • Duraisingh, M.T.1    Curtis, J.2    Warhurst, D.C.3
  • 17
    • 0023227947 scopus 로고
    • Sulfadoxine assay using capillary blood samples dried on filter paper suitable for monitoring of drug concentrations in the field
    • Bergqvist Y, Hjelm E, Rombo L, 1987. Sulfadoxine assay using capillary blood samples dried on filter paper suitable for monitoring of drug concentrations in the field, Ther: Drug Monit 9: 203-207.
    • (1987) Ther Drug Monit , vol.9 , pp. 203-207
    • Bergqvist, Y.1    Hjelm, E.2    Rombo, L.3
  • 18
    • 0025781766 scopus 로고
    • A case of Plasmodium falciparum sensitive to chloroquine but resistant to PYR/SDX in Sinnar/Sudan
    • Ibrahim ME, EL Kariem FA, EL Hassan IM, Mubark H, 1991. A case of Plasmodium falciparum sensitive to chloroquine but resistant to PYR/SDX in Sinnar/Sudan. Trans R Soc Trop Med Hyg 85: 446.
    • (1991) Trans R Soc Trop Med Hyg , vol.85 , pp. 446
    • Ibrahim, M.E.1    El Kariem, F.A.2    El Hassan, I.M.3    Mubark, H.4
  • 19
    • 0030607416 scopus 로고    scopus 로고
    • Recombinant Plasmodium falciparum dihydrofolate reductase based on in vitro screen for antifolate antimalarials
    • Brobey RK, Sano G, Itoh F, Aso K, Kimura M, Mitamura T, 1996. Recombinant Plasmodium falciparum dihydrofolate reductase based on in vitro screen for antifolate antimalarials. Mol Biochem Parasitol 81: 225-237.
    • (1996) Mol Biochem Parasitol , vol.81 , pp. 225-237
    • Brobey, R.K.1    Sano, G.2    Itoh, F.3    Aso, K.4    Kimura, M.5    Mitamura, T.6
  • 20
    • 0030035041 scopus 로고    scopus 로고
    • Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine
    • Wu Y, Kirkman LA, Wellems TE, 1996. Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine. Proc Natl Acad Sci U S A 93: 1130-1134.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 1130-1134
    • Wu, Y.1    Kirkman, L.A.2    Wellems, T.E.3
  • 21
    • 0030678031 scopus 로고    scopus 로고
    • High prevalence of mutations in the dihydrofolate reductase gene of Plasmodium falciparum isolates from Tanzania without evidence of an association to clinical pyrimethamine/sulfadoxine resistance
    • Jelinek T, Rønn AM, Curtis J, Duraisingh MT, Lemnge MM, Bygbjerg IC, Warhurst DC, 1997. High prevalence of mutations in the dihydrofolate reductase gene of Plasmodium falciparum isolates from Tanzania without evidence of an association to clinical pyrimethamine/sulfadoxine resistance. Trop Med Int Health 2: 1025-1027.
    • (1997) Trop Med Int Health , vol.2 , pp. 1025-1027
    • Jelinek, T.1    Rønn, A.M.2    Curtis, J.3    Duraisingh, M.T.4    Lemnge, M.M.5    Bygbjerg, I.C.6    Warhurst, D.C.7
  • 22
    • 0032777792 scopus 로고    scopus 로고
    • Lack of an association between the Asn 108 mutation in the dihydrofolate reductase gene and in vivo resistance to pyrimethamine/sulfadoxine in Plasmodium falciparum
    • Rallon N, Osorio L, Giraldo L, 1999. Lack of an association between the Asn 108 mutation in the dihydrofolate reductase gene and in vivo resistance to pyrimethamine/sulfadoxine in Plasmodium falciparum. Am J Trop Med Hyg 61: 245-248.
    • (1999) Am J Trop Med Hyg , vol.61 , pp. 245-248
    • Rallon, N.1    Osorio, L.2    Giraldo, L.3
  • 23
    • 0034065697 scopus 로고    scopus 로고
    • Towards an understanding of the mechanism of pyrimethamine/sulfadoxine resistance in P. falciparum: Genotyping of dhfr and dhps of Kenyan parasites
    • Nzila-Mounda, Mberu EK, Sulo J, Dayo H, Winstanley PA, Sibley CH, Watkins WM, 2000.Towards an understanding of the mechanism of pyrimethamine/sulfadoxine resistance in P. falciparum: genotyping of dhfr and dhps of Kenyan parasites. Antimicrob Agent Chemother 44: 991-996.
    • (2000) Antimicrob Agent Chemother , vol.44 , pp. 991-996
    • Nzila-Mounda1    Mberu, E.K.2    Sulo, J.3    Dayo, H.4    Winstanley, P.A.5    Sibley, C.H.6    Watkins, W.M.7
  • 24
    • 0032842337 scopus 로고    scopus 로고
    • P. falciparum resistance to sulfadoxine/pyrimethamine in Uganda: Correlation to polymorphisms in the dihydrofolate reductase (dhfr) and dihydropetroate synthase (dhps) genes
    • Jelinek T, Kilian A, Kabagambe G, Von Sonnenburg F, 1999. P. falciparum resistance to sulfadoxine/pyrimethamine in Uganda: correlation to polymorphisms in the dihydrofolate reductase (dhfr) and dihydropetroate synthase (dhps) genes. Am J Trop Med Hyg 61: 463-466.
    • (1999) Am J Trop Med Hyg , vol.61 , pp. 463-466
    • Jelinek, T.1    Kilian, A.2    Kabagambe, G.3    Von Sonnenburg, F.4
  • 26
    • 0035350481 scopus 로고    scopus 로고
    • Can pretreatment screening for dhps and dhfr mutations in P. falciparum infections be used to predict sulfadoxine/pyrimethamine treatment failure?
    • Omar SA, Adagu IS, Warhurst DC, 2001. Can pretreatment screening for dhps and dhfr mutations in P. falciparum infections be used to predict sulfadoxine/pyrimethamine treatment failure? Trans R Soc Trop Med Hyg 95: 315-319.
    • (2001) Trans R Soc Trop Med Hyg , vol.95 , pp. 315-319
    • Omar, S.A.1    Adagu, I.S.2    Warhurst, D.C.3
  • 27
    • 0035884456 scopus 로고    scopus 로고
    • Chloroquine resistant malaria
    • Wellems TE, Plowe CV, 2001. Chloroquine resistant malaria. J Infect Dis 184: 770-776.
    • (2001) J Infect Dis , vol.184 , pp. 770-776
    • Wellems, T.E.1    Plowe, C.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.