Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 25, 1997, Pages 13944-13949

  Triglia, Tony ^a   Menting, John G T ^a   Wilson, Craig ^b   Cowman, Alan F ^a,c  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Drug resistance; Malaria; Sulfadoxine

Indexed keywords

DIHYDROPTEROATE SYNTHASE; SULFONAMIDE; SULFONE;

ALLELE; AMINO ACID SEQUENCE; ARTICLE; DRUG SENSITIVITY; DRUG TARGETING; ESCHERICHIA COLI; GENE MUTATION; MALARIA FALCIPARUM; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

ANIMALS; ANTIMALARIALS; BASE SEQUENCE; DIHYDROPTEROATE SYNTHASE; DNA, PROTOZOAN; DRUG RESISTANCE; ENZYME INHIBITORS; ESCHERICHIA COLI; HUMANS; KINETICS; MULTIENZYME COMPLEXES; MUTATION; PLASMODIUM FALCIPARUM; SULFADOXINE; SULFONAMIDES; SULFONES;

ESCHERICHIA COLI; PLASMODIUM FALCIPARUM;

EID: 0031444278     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.25.13944     Document Type: Article

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