메뉴 건너뛰기




Volumn 27, Issue 4, 2013, Pages 315-331

What is the role of erythropoietin in acute myocardial infarct? Bridging the gap between experimental models and clinical trials

Author keywords

Acute myocardial infarction; Cardioprotection; Clinical trials; Erythropoietin; Experimental models; Reperfusion injury

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIDIABETIC AGENT; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ERYTHROPOIETIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MORPHINE; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; RECOMBINANT ERYTHROPOIETIN;

EID: 84880253976     PISSN: 09203206     EISSN: 15737241     Source Type: Journal    
DOI: 10.1007/s10557-013-6461-1     Document Type: Review
Times cited : (19)

References (139)
  • 1
    • 10944239058 scopus 로고    scopus 로고
    • ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of Patients with Acute Myocardial Infarction)
    • 15339869 10.1161/01.CIR.0000134791.68010.FA
    • Antman EM, Anbe DT, Armstrong PW, et al. ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of Patients with Acute Myocardial Infarction). Circulation. 2004;110:e82-292.
    • (2004) Circulation , vol.110 , pp. 82-292
    • Antman, E.M.1    Anbe, D.T.2    Armstrong, P.W.3
  • 2
    • 84880266857 scopus 로고    scopus 로고
    • WHO updated June 2011
    • WHO. WHO fact sheet N 310, updated June 2011; 2011.
    • (2011) WHO Fact Sheet N 310
  • 3
    • 34548746306 scopus 로고    scopus 로고
    • Myocardial reperfusion injury
    • 17855673 1:CAS:528:DC%2BD2sXhtVKgtLzF 10.1056/NEJMra071667
    • Yellon DM, Hausenloy DJ. Myocardial reperfusion injury. N Engl J Med. 2007;357:1121-35.
    • (2007) N Engl J Med , vol.357 , pp. 1121-1135
    • Yellon, D.M.1    Hausenloy, D.J.2
  • 4
    • 48249109117 scopus 로고    scopus 로고
    • Effect of cyclosporine on reperfusion injury in acute myocardial infarction
    • 18669426 1:CAS:528:DC%2BD1cXpt1Sgsr4%3D 10.1056/NEJMoa071142
    • Piot C, Croisille P, Staat P, et al. Effect of cyclosporine on reperfusion injury in acute myocardial infarction. N Engl J Med. 2008;359:473-81.
    • (2008) N Engl J Med , vol.359 , pp. 473-481
    • Piot, C.1    Croisille, P.2    Staat, P.3
  • 5
    • 26944445765 scopus 로고    scopus 로고
    • Postconditioning the human heart
    • 16186417 10.1161/CIRCULATIONAHA.105.558122
    • Staat P, Rioufol G, Piot C, et al. Postconditioning the human heart. Circulation. 2005;112:2143-8.
    • (2005) Circulation , vol.112 , pp. 2143-2148
    • Staat, P.1    Rioufol, G.2    Piot, C.3
  • 6
    • 40749130846 scopus 로고    scopus 로고
    • Long-term benefit of postconditioning
    • 18268150 1:CAS:528:DC%2BD1cXhvVylurw%3D 10.1161/CIRCULATIONAHA.107.729780
    • Thibault H, Piot C, Staat P, et al. Long-term benefit of postconditioning. Circulation. 2008;117:1037-44.
    • (2008) Circulation , vol.117 , pp. 1037-1044
    • Thibault, H.1    Piot, C.2    Staat, P.3
  • 7
    • 84861863228 scopus 로고    scopus 로고
    • Post-conditioning reduces infarct size and edema in patients with ST-segment elevation myocardial infarction
    • 22676937 10.1016/j.jacc.2012.03.026
    • Thuny F, Lairez O, Roubille F, et al. Post-conditioning reduces infarct size and edema in patients with ST-segment elevation myocardial infarction. J Am Coll Cardiol. 2012;59:2175-81.
    • (2012) J Am Coll Cardiol , vol.59 , pp. 2175-2181
    • Thuny, F.1    Lairez, O.2    Roubille, F.3
  • 8
    • 0028340331 scopus 로고
    • Biology of erythropoietin
    • 1:STN:280:DyaK2M%2FjslCqsg%3D%3D
    • Jelkmann W. Biology of erythropoietin. Clin Invest. 1994;72(6 Suppl):S3-10.
    • (1994) Clin Invest , vol.72 , Issue.6 SUPPL. , pp. 3-10
    • Jelkmann, W.1
  • 9
    • 80051978444 scopus 로고    scopus 로고
    • Neuroprotective effect of ligustilide against ischaemia-reperfusion injury via up-regulation of erythropoietin and down-regulation of RTP801
    • 1:CAS:528:DC%2BC3MXhtFWqsLbK 10.1111/j.1476-5381.2011.01337.x
    • Wu XM, Qian ZM, Zhu L, et al. Neuroprotective effect of ligustilide against ischaemia-reperfusion injury via up-regulation of erythropoietin and down-regulation of RTP801. Brit J Pharmacol. 2011;164:332-43.
    • (2011) Brit J Pharmacol , vol.164 , pp. 332-343
    • Wu, X.M.1    Qian, Z.M.2    Zhu, L.3
  • 10
    • 0035957426 scopus 로고    scopus 로고
    • Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress
    • 11259643 1:CAS:528:DC%2BD3MXis1Khtrg%3D 10.1073/pnas.051606598
    • Siren AL, Fratelli M, Brines M, et al. Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress. Proc Natl Acad Sci U S A. 2001;98:4044-9.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4044-4049
    • Siren, A.L.1    Fratelli, M.2    Brines, M.3
  • 11
    • 0036896201 scopus 로고    scopus 로고
    • Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: Evidence from an in vitro model
    • 12451129 1:CAS:528:DC%2BD38XpsVamsLk%3D
    • Ruscher K, Freyer D, Karsch M, et al. Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model. J Neurosci. 2002;22:10291-301.
    • (2002) J Neurosci , vol.22 , pp. 10291-10301
    • Ruscher, K.1    Freyer, D.2    Karsch, M.3
  • 12
    • 0037365196 scopus 로고    scopus 로고
    • Erythropoietin fosters both intrinsic and extrinsic neuronal protection through modulation of microglia, Akt1, Bad, and caspase-mediated pathways
    • 1:CAS:528:DC%2BD3sXjtVahsbc%3D 10.1038/sj.bjp.0705161
    • Chong ZZ, Kang JQ, Maiese K. Erythropoietin fosters both intrinsic and extrinsic neuronal protection through modulation of microglia, Akt1, Bad, and caspase-mediated pathways. Brit J Pharmacol. 2003;138:1107-18.
    • (2003) Brit J Pharmacol , vol.138 , pp. 1107-1118
    • Chong, Z.Z.1    Kang, J.Q.2    Maiese, K.3
  • 13
    • 6944237300 scopus 로고    scopus 로고
    • Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor
    • 15456912 1:CAS:528:DC%2BD2cXovVyis7w%3D 10.1073/pnas.0406491101
    • Brines M, Grasso G, Fiordaliso F, et al. Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor. Proc Natl Acad Sci U S A. 2004;101:14907-12.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 14907-14912
    • Brines, M.1    Grasso, G.2    Fiordaliso, F.3
  • 14
    • 0036064271 scopus 로고    scopus 로고
    • HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration
    • 12068288 1:CAS:528:DC%2BD38XkvFehsbc%3D 10.1038/nm723
    • Grimm C, Wenzel A, Groszer M, et al. HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration. Nat Med. 2002;8:718-24.
    • (2002) Nat Med , vol.8 , pp. 718-724
    • Grimm, C.1    Wenzel, A.2    Groszer, M.3
  • 15
    • 0036678821 scopus 로고    scopus 로고
    • Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury
    • 12130665 1:CAS:528:DC%2BD38Xmt1ChsbY%3D 10.1073/pnas.152321399
    • Junk AK, Mammis A, Savitz SI, et al. Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury. Proc Natl Acad Sci U S A. 2002;99:10659-64.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 10659-10664
    • Junk, A.K.1    Mammis, A.2    Savitz, S.I.3
  • 16
    • 0037016065 scopus 로고    scopus 로고
    • Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases
    • 12460881 1:CAS:528:DC%2BD38XovVelt74%3D 10.1161/01.CIR.0000039103.58920. 1F
    • Chong ZZ, Kang JQ, Maiese K. Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases. Circulation. 2002;106:2973-9.
    • (2002) Circulation , vol.106 , pp. 2973-2979
    • Chong, Z.Z.1    Kang, J.Q.2    Maiese, K.3
  • 17
    • 70449512992 scopus 로고    scopus 로고
    • Low-dose darbepoetin alpha attenuates progression of a mouse model of aristolochic acid nephropathy through early tubular protection
    • 19907192 1:CAS:528:DC%2BC3cXitlWls7g%3D 10.1159/000256569
    • Hamano Y, Aoki T, Shirai R, et al. Low-dose darbepoetin alpha attenuates progression of a mouse model of aristolochic acid nephropathy through early tubular protection. Nephron Exp Nephrol. 2010;114:e69-81.
    • (2010) Nephron Exp Nephrol , vol.114 , pp. 69-81
    • Hamano, Y.1    Aoki, T.2    Shirai, R.3
  • 18
    • 4344675279 scopus 로고    scopus 로고
    • Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo
    • 15327391 1:CAS:528:DC%2BD2cXnvVCrt7k%3D 10.1111/j.1523-1755.2004.00847.x
    • Patel NS, Sharples EJ, Cuzzocrea S, et al. Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo. Kidney Int. 2004;66:983-9.
    • (2004) Kidney Int , vol.66 , pp. 983-989
    • Patel, N.S.1    Sharples, E.J.2    Cuzzocrea, S.3
  • 19
    • 0016618531 scopus 로고
    • Growth stimulation of human bone marrow cells in agar culture by vascular cells
    • 1081892 1:STN:280:DyaE28%2FovFGgsQ%3D%3D
    • Knudtzon S, Mortensen BT. Growth stimulation of human bone marrow cells in agar culture by vascular cells. Blood. 1975;46:937-43.
    • (1975) Blood , vol.46 , pp. 937-943
    • Knudtzon, S.1    Mortensen, B.T.2
  • 20
    • 0025297296 scopus 로고
    • Erythropoietin has a mitogenic and positive chemotactic effect on endothelial cells
    • 2165612 1:CAS:528:DyaK3cXlt1OisLc%3D 10.1073/pnas.87.15.5978
    • Anagnostou A, Lee ES, Kessimian N, Levinson R, Steiner M. Erythropoietin has a mitogenic and positive chemotactic effect on endothelial cells. Proc Natl Acad Sci U S A. 1990;87:5978-82.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 5978-5982
    • Anagnostou, A.1    Lee, E.S.2    Kessimian, N.3    Levinson, R.4    Steiner, M.5
  • 21
    • 0042738942 scopus 로고    scopus 로고
    • Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization
    • 12702503 1:CAS:528:DC%2BD3sXmsFWktrs%3D 10.1182/blood-2003-01-0223
    • Heeschen C, Aicher A, Lehmann R, et al. Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization. Blood. 2003;102:1340-6.
    • (2003) Blood , vol.102 , pp. 1340-1346
    • Heeschen, C.1    Aicher, A.2    Lehmann, R.3
  • 22
    • 34848832453 scopus 로고    scopus 로고
    • Erythropoietin improves cardiac function through endothelial progenitor cell and vascular endothelial growth factor mediated neovascularization
    • 17576662 1:CAS:528:DC%2BD2sXhtV2mtbzM 10.1093/eurheartj/ehm177
    • Westenbrink BD, Lipsic E, van der Meer P, et al. Erythropoietin improves cardiac function through endothelial progenitor cell and vascular endothelial growth factor mediated neovascularization. Eur Heart J. 2007;28:2018-27.
    • (2007) Eur Heart J , vol.28 , pp. 2018-2027
    • Westenbrink, B.D.1    Lipsic, E.2    Van Der Meer, P.3
  • 23
    • 49449099816 scopus 로고    scopus 로고
    • Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin
    • 18676614 1:CAS:528:DC%2BD1cXpvFOis78%3D 10.1073/pnas.0805594105
    • Brines M, Patel NS, Villa P, et al. Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin. Proc Natl Acad Sci U S A. 2008;105:10925-30.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 10925-10930
    • Brines, M.1    Patel, N.S.2    Villa, P.3
  • 24
    • 0032824560 scopus 로고    scopus 로고
    • Inactivation of erythropoietin leads to defects in cardiac morphogenesis
    • 10409505 1:CAS:528:DyaK1MXlvV2qu7w%3D
    • Wu H, Lee SH, Gao J, Liu X, Iruela-Arispe ML. Inactivation of erythropoietin leads to defects in cardiac morphogenesis. Development. 1999;126:3597-605.
    • (1999) Development , vol.126 , pp. 3597-3605
    • Wu, H.1    Lee, S.H.2    Gao, J.3    Liu, X.4    Iruela-Arispe, M.L.5
  • 25
    • 0037447256 scopus 로고    scopus 로고
    • Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling
    • 12663857 1:CAS:528:DC%2BD3sXjt12nsbs%3D 10.1073/pnas.0630444100
    • Calvillo L, Latini R, Kajstura J, et al. Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling. Proc Natl Acad Sci U S A. 2003;100:4802-6.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 4802-4806
    • Calvillo, L.1    Latini, R.2    Kajstura, J.3
  • 26
    • 85047691007 scopus 로고    scopus 로고
    • A novel protective effect of erythropoietin in the infarcted heart
    • 14523037 1:CAS:528:DC%2BD3sXnvFGrsL0%3D
    • Parsa CJ, Matsumoto A, Kim J, et al. A novel protective effect of erythropoietin in the infarcted heart. J Clin Invest. 2003;112:999-1007.
    • (2003) J Clin Invest , vol.112 , pp. 999-1007
    • Parsa, C.J.1    Matsumoto, A.2    Kim, J.3
  • 27
    • 6344225691 scopus 로고    scopus 로고
    • Erythropoietin receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury
    • 1:CAS:528:DC%2BD2cXkslWiur8%3D
    • Wright GL, Hanlon P, Amin K, Steenbergen C, Murphy E, Arcasoy MO. Erythropoietin receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury. FASEB. 2004;18:1031-3.
    • (2004) FASEB , vol.18 , pp. 1031-1033
    • Wright, G.L.1    Hanlon, P.2    Amin, K.3    Steenbergen, C.4    Murphy, E.5    Arcasoy, M.O.6
  • 28
    • 34547101451 scopus 로고    scopus 로고
    • Darbepoetin alfa, a long-acting erythropoietin analog, offers novel and delayed cardioprotection for the ischemic heart
    • 17384131 1:CAS:528:DC%2BD2sXovVyitLg%3D 10.1152/ajpheart.00227.2007
    • Gao E, Boucher M, Chuprun JK, Zhou RH, Eckhart AD, Koch WJ. Darbepoetin alfa, a long-acting erythropoietin analog, offers novel and delayed cardioprotection for the ischemic heart. Am J Physiol Heart Circ Physiol. 2007;293:H60-8.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293 , pp. 60-68
    • Gao, E.1    Boucher, M.2    Chuprun, J.K.3    Zhou, R.H.4    Eckhart, A.D.5    Koch, W.J.6
  • 29
    • 34447513916 scopus 로고    scopus 로고
    • Positive effect of darbepoetin on peri-infarction remodeling in a porcine model of myocardial ischemia-reperfusion
    • 17597149 1:CAS:528:DC%2BD2sXnvF2ls7o%3D 10.1016/j.yjmcc.2007.05.014
    • Toma C, Letts DP, Tanabe M, Gorcsan 3rd J, Counihan PJ. Positive effect of darbepoetin on peri-infarction remodeling in a porcine model of myocardial ischemia-reperfusion. J Mol Cell Cardiol. 2007;43:130-6.
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 130-136
    • Toma, C.1    Letts, D.P.2    Tanabe, M.3    Gorcsan III, J.4    Counihan, P.J.5
  • 30
    • 20944439418 scopus 로고    scopus 로고
    • High serum erythropoietin level is associated with smaller infarct size in patients with acute myocardial infarction who undergo successful primary percutaneous coronary intervention
    • 15862410 1:CAS:528:DC%2BD2MXjvVKku7o%3D 10.1016/j.jacc.2005.01.043
    • Namiuchi S, Kagaya Y, Ohta J, et al. High serum erythropoietin level is associated with smaller infarct size in patients with acute myocardial infarction who undergo successful primary percutaneous coronary intervention. J Am Coll Cardiol. 2005;45:1406-12.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1406-1412
    • Namiuchi, S.1    Kagaya, Y.2    Ohta, J.3
  • 31
    • 77953223654 scopus 로고    scopus 로고
    • Sonic hedgehog is a critical mediator of erythropoietin-induced cardiac protection in mice
    • 20484812 1:CAS:528:DC%2BC3cXnt1KqtLk%3D 10.1172/JCI39896
    • Ueda K, Takano H, Niitsuma Y, et al. Sonic hedgehog is a critical mediator of erythropoietin-induced cardiac protection in mice. J Clin Invest. 2010;120:2016-29.
    • (2010) J Clin Invest , vol.120 , pp. 2016-2029
    • Ueda, K.1    Takano, H.2    Niitsuma, Y.3
  • 32
    • 36248931074 scopus 로고    scopus 로고
    • Erythropoietin enhances the angiogenic potency of autologous bone marrow stromal cells in a rat model of myocardial infarction
    • 17106196 1:CAS:528:DC%2BD2sXht12ktLjM 10.1159/000096803
    • Zhang D, Zhang F, Zhang Y, et al. Erythropoietin enhances the angiogenic potency of autologous bone marrow stromal cells in a rat model of myocardial infarction. Cardiology. 2007;108:228-36.
    • (2007) Cardiology , vol.108 , pp. 228-236
    • Zhang, D.1    Zhang, F.2    Zhang, Y.3
  • 33
    • 84861122819 scopus 로고    scopus 로고
    • Effects of erythropoietin on angiogenesis after myocardial infarction in porcine
    • 10.1007/s00380-011-0197-2
    • Kawachi K, Iso Y, Sato T, et al. Effects of erythropoietin on angiogenesis after myocardial infarction in porcine. Hear Vessel. 2012;27:79-88.
    • (2012) Hear Vessel , vol.27 , pp. 79-88
    • Kawachi, K.1    Iso, Y.2    Sato, T.3
  • 34
    • 84856699747 scopus 로고    scopus 로고
    • Nonerythropoietic properties of erythropoietin: Implication for tissue protection
    • 22011619 1:CAS:528:DC%2BC3MXhtlOmsLzO
    • Rathod DB, Salahudeen AK. Nonerythropoietic properties of erythropoietin: implication for tissue protection. J Investig Med. 2011;59:1083-5.
    • (2011) J Investig Med , vol.59 , pp. 1083-1085
    • Rathod, D.B.1    Salahudeen, A.K.2
  • 36
    • 80054993756 scopus 로고    scopus 로고
    • Promises and pitfalls in erythopoietin-mediated tissue protection: Are nonerythropoietic derivatives a way forward?
    • 20683348 1:CAS:528:DC%2BC3MXhtlOmsLzN
    • Hand CC, Brines M. Promises and pitfalls in erythopoietin-mediated tissue protection: are nonerythropoietic derivatives a way forward? J Investig Med. 2011;59:1073-82.
    • (2011) J Investig Med , vol.59 , pp. 1073-1082
    • Hand, C.C.1    Brines, M.2
  • 37
    • 53549097076 scopus 로고    scopus 로고
    • Erythropoietin-mediated tissue protection: Reducing collateral damage from the primary injury response
    • 1:CAS:528:DC%2BD1cXhsVemtr7F 10.1111/j.1365-2796.2008.02024.x
    • Brines M, Cerami A. Erythropoietin-mediated tissue protection: reducing collateral damage from the primary injury response. J Int Med. 2008;264:405-32.
    • (2008) J Int Med , vol.264 , pp. 405-432
    • Brines, M.1    Cerami, A.2
  • 38
    • 36348966705 scopus 로고    scopus 로고
    • Cellular protection by erythropoietin: New therapeutic implications?
    • 17717190 1:CAS:528:DC%2BD2sXhsVSgsL3L 10.1124/jpet.107.127357
    • Joyeux-Faure M. Cellular protection by erythropoietin: new therapeutic implications? J Pharmacol Exp Ther. 2007;323:759-62.
    • (2007) J Pharmacol Exp Ther , vol.323 , pp. 759-762
    • Joyeux-Faure, M.1
  • 39
    • 11244333356 scopus 로고    scopus 로고
    • New avenues of exploration for erythropoietin
    • 15632341 1:CAS:528:DC%2BD2MXht1Gmtw%3D%3D 10.1001/jama.293.1.90
    • Maiese K, Li F, Chong ZZ. New avenues of exploration for erythropoietin. JAMA. 2005;293:90-5.
    • (2005) JAMA , vol.293 , pp. 90-95
    • Maiese, K.1    Li, F.2    Chong, Z.Z.3
  • 40
    • 84863829222 scopus 로고    scopus 로고
    • Current perspectives on protective roles of erythropoietin in cardiovascular system: Erythropoietin receptor as a novel therapeutic target
    • 22688525 1:CAS:528:DC%2BC38XhtFKntrvN 10.1620/tjem.227.83
    • Kagaya Y, Asaumi Y, Wang W, et al. Current perspectives on protective roles of erythropoietin in cardiovascular system: erythropoietin receptor as a novel therapeutic target. Tohoku J Exp Med. 2012;227:83-91.
    • (2012) Tohoku J Exp Med , vol.227 , pp. 83-91
    • Kagaya, Y.1    Asaumi, Y.2    Wang, W.3
  • 41
    • 0038163900 scopus 로고    scopus 로고
    • Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury
    • 12796124 1:CAS:528:DC%2BD3sXkvFyjtLs%3D 10.1161/01.CIR.0000078635.89229. 8A
    • Cai Z, Manalo DJ, Wei G, et al. Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury. Circulation. 2003;108:79-85.
    • (2003) Circulation , vol.108 , pp. 79-85
    • Cai, Z.1    Manalo, D.J.2    Wei, G.3
  • 42
    • 0141593556 scopus 로고    scopus 로고
    • Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats
    • 14500913 1:CAS:528:DC%2BD3sXotFKmt7k%3D 10.1073/pnas.1930406100
    • Moon C, Krawczyk M, Ahn D, et al. Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats. Proc Natl Acad Sci U S A. 2003;100:11612-7.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 11612-11617
    • Moon, C.1    Krawczyk, M.2    Ahn, D.3
  • 43
    • 0041659121 scopus 로고    scopus 로고
    • Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway
    • 12927817 1:CAS:528:DC%2BD3sXmsVGku7c%3D 10.1016/S0006-291X(03)01503-1
    • Tramontano AF, Muniyappa R, Black AD, et al. Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway. Biochem Biophys Res Commun. 2003;308:990-4.
    • (2003) Biochem Biophys Res Commun , vol.308 , pp. 990-994
    • Tramontano, A.F.1    Muniyappa, R.2    Black, A.D.3
  • 44
    • 2442587705 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-kinase signaling is required for erythropoietin-mediated acute protection against myocardial ischemia/reperfusion injury
    • 15117842 1:CAS:528:DC%2BD2cXjsVWqsrk%3D 10.1161/01.CIR.0000127954.98131. 23
    • Cai Z, Semenza GL. Phosphatidylinositol-3-kinase signaling is required for erythropoietin-mediated acute protection against myocardial ischemia/reperfusion injury. Circulation. 2004;109:2050-3.
    • (2004) Circulation , vol.109 , pp. 2050-2053
    • Cai, Z.1    Semenza, G.L.2
  • 45
    • 70349741332 scopus 로고    scopus 로고
    • Short- and long-term cardioprotective effect of darbepoetin-alpha: Role of Bcl-2 family proteins
    • 19597369 1:CAS:528:DC%2BD1MXhtFGhsb7I 10.1097/FJC.0b013e3181b04d01
    • Schlecht-Bauer D, Antier D, Machet MC, Hyvelin JM. Short- and long-term cardioprotective effect of darbepoetin-alpha: role of Bcl-2 family proteins. J Cardiovasc Pharmacol. 2009;54:223-31.
    • (2009) J Cardiovasc Pharmacol , vol.54 , pp. 223-231
    • Schlecht-Bauer, D.1    Antier, D.2    Machet, M.C.3    Hyvelin, J.M.4
  • 46
    • 18744378310 scopus 로고    scopus 로고
    • Recombinant human erythropoietin pretreatment attenuates myocardial infarct size: A possible mechanism involves heat shock Protein 70 and attenuation of nuclear factor-kappaB
    • 15943180 1:CAS:528:DC%2BD2MXlsFalsbg%3D
    • Xu B, Dong GH, Liu H, Wang YQ, Wu HW, Jing H. Recombinant human erythropoietin pretreatment attenuates myocardial infarct size: a possible mechanism involves heat shock Protein 70 and attenuation of nuclear factor-kappaB. Ann Clin Lab Sci. 2005;35:161-8.
    • (2005) Ann Clin Lab Sci , vol.35 , pp. 161-168
    • Xu, B.1    Dong, G.H.2    Liu, H.3    Wang, Y.Q.4    Wu, H.W.5    Jing, H.6
  • 47
    • 33645020150 scopus 로고    scopus 로고
    • Early pharmacological preconditioning by erythropoietin mediated by inducible NOS and mitochondrial ATP-dependent potassium channels in the rat heart
    • 16448394 1:CAS:528:DC%2BD28XitVajsL0%3D 10.1111/j.1472-8206.2005.00392.x
    • Joyeux-Faure M, Ramond A, Beguin PC, Belaidi E, Godin-Ribuot D, Ribuot C. Early pharmacological preconditioning by erythropoietin mediated by inducible NOS and mitochondrial ATP-dependent potassium channels in the rat heart. Fundam Clin Pharmacol. 2006;20:51-6.
    • (2006) Fundam Clin Pharmacol , vol.20 , pp. 51-56
    • Joyeux-Faure, M.1    Ramond, A.2    Beguin, P.C.3    Belaidi, E.4    Godin-Ribuot, D.5    Ribuot, C.6
  • 48
    • 33748137740 scopus 로고    scopus 로고
    • Erythropoietin protects cardiomyocytes from apoptosis via up-regulation of endothelial nitric oxide synthase
    • 16904088 1:CAS:528:DC%2BD28XpsVWqt70%3D 10.1016/j.cardiores.2006.06.026
    • Burger D, Lei M, Geoghegan-Morphet N, Lu X, Xenocostas A, Feng Q. Erythropoietin protects cardiomyocytes from apoptosis via up-regulation of endothelial nitric oxide synthase. Cardiovasc Res. 2006;72:51-9.
    • (2006) Cardiovasc Res , vol.72 , pp. 51-59
    • Burger, D.1    Lei, M.2    Geoghegan-Morphet, N.3    Lu, X.4    Xenocostas, A.5    Feng, Q.6
  • 49
    • 58149495970 scopus 로고    scopus 로고
    • Role of heme oxygenase-1 in the cardioprotective effects of erythropoietin during myocardial ischemia and reperfusion
    • 18996987 1:CAS:528:DC%2BD1MXhtVyhu78%3D 10.1152/ajpheart.00372.2008
    • Burger D, Xiang F, Hammoud L, Lu X, Feng Q. Role of heme oxygenase-1 in the cardioprotective effects of erythropoietin during myocardial ischemia and reperfusion. Am J Physiol Heart Circ Physiol. 2009;296:H84-93.
    • (2009) Am J Physiol Heart Circ Physiol , vol.296 , pp. 84-93
    • Burger, D.1    Xiang, F.2    Hammoud, L.3    Lu, X.4    Feng, Q.5
  • 50
    • 64749104944 scopus 로고    scopus 로고
    • Erythropoietin protects from reperfusion-induced myocardial injury by enhancing coronary endothelial nitric oxide production
    • 19237290 10.1016/j.ejcts.2008.12.049
    • Mihov D, Bogdanov N, Grenacher B, Gassmann M, Zund G, Bogdanova A, et al. Erythropoietin protects from reperfusion-induced myocardial injury by enhancing coronary endothelial nitric oxide production. Eur J Cardiothorac Surg. 2009;35:839-46.
    • (2009) Eur J Cardiothorac Surg , vol.35 , pp. 839-846
    • Mihov, D.1    Bogdanov, N.2    Grenacher, B.3    Gassmann, M.4    Zund, G.5    Bogdanova, A.6
  • 52
    • 77749317193 scopus 로고    scopus 로고
    • The therapeutic potential of erythropoiesis-stimulating agents for tissue protection: A tale of two receptors
    • 20093809 1:CAS:528:DC%2BC3cXksFCntQ%3D%3D 10.1159/000245630
    • Brines M. The therapeutic potential of erythropoiesis-stimulating agents for tissue protection: a tale of two receptors. Blood Purif. 2010;29:86-92.
    • (2010) Blood Purif , vol.29 , pp. 86-92
    • Brines, M.1
  • 53
    • 13844320400 scopus 로고    scopus 로고
    • A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury
    • 15671158 1:CAS:528:DC%2BD2MXhvFGru7g%3D 10.1073/pnas.0409329102
    • Fiordaliso F, Chimenti S, Staszewsky L, et al. A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury. Proc Natl Acad Sci U S A. 2005;102:2046-51.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2046-2051
    • Fiordaliso, F.1    Chimenti, S.2    Staszewsky, L.3
  • 54
    • 12344335260 scopus 로고    scopus 로고
    • Erythropoietin prevents the acute myocardial inflammatory response induced by ischemia/reperfusion via induction of AP-1
    • 15664399 1:CAS:528:DC%2BD2MXmsVKksQ%3D%3D 10.1016/j.cardiores.2004.11.019
    • Rui T, Feng Q, Lei M, et al. Erythropoietin prevents the acute myocardial inflammatory response induced by ischemia/reperfusion via induction of AP-1. Cardiovasc Res. 2005;65:719-27.
    • (2005) Cardiovasc Res , vol.65 , pp. 719-727
    • Rui, T.1    Feng, Q.2    Lei, M.3
  • 55
    • 33746269418 scopus 로고    scopus 로고
    • Endogenous erythropoietin system in non-hematopoietic lineage cells plays a protective role in myocardial ischemia/reperfusion
    • 16781691 1:CAS:528:DC%2BD28Xns12mt78%3D 10.1016/j.cardiores.2006.05.010
    • Tada H, Kagaya Y, Takeda M, et al. Endogenous erythropoietin system in non-hematopoietic lineage cells plays a protective role in myocardial ischemia/reperfusion. Cardiovasc Res. 2006;71:466-77.
    • (2006) Cardiovasc Res , vol.71 , pp. 466-477
    • Tada, H.1    Kagaya, Y.2    Takeda, M.3
  • 56
    • 34247201113 scopus 로고    scopus 로고
    • Protective role of endogenous erythropoietin system in nonhematopoietic cells against pressure overload-induced left ventricular dysfunction in mice
    • 17404160 1:CAS:528:DC%2BD2sXjvFKjtbc%3D 10.1161/CIRCULATIONAHA.106.659037
    • Asaumi Y, Kagaya Y, Takeda M, et al. Protective role of endogenous erythropoietin system in nonhematopoietic cells against pressure overload-induced left ventricular dysfunction in mice. Circulation. 2007;115:2022-32.
    • (2007) Circulation , vol.115 , pp. 2022-2032
    • Asaumi, Y.1    Kagaya, Y.2    Takeda, M.3
  • 57
    • 66749100836 scopus 로고    scopus 로고
    • Erythropoietin protects the heart from ventricular arrhythmia during ischemia and reperfusion via neuronal nitric-oxide synthase
    • 19307451 1:CAS:528:DC%2BD1MXms1ehur4%3D 10.1124/jpet.109.150896
    • Burger DE, Xiang FL, Hammoud L, Jones DL, Feng Q. Erythropoietin protects the heart from ventricular arrhythmia during ischemia and reperfusion via neuronal nitric-oxide synthase. J Pharmacol Exp Ther. 2009;329:900-7.
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 900-907
    • Burger, D.E.1    Xiang, F.L.2    Hammoud, L.3    Jones, D.L.4    Feng, Q.5
  • 58
    • 8844247185 scopus 로고    scopus 로고
    • Erythropoietin improves left ventricular function and coronary flow in an experimental model of ischemia-reperfusion injury
    • 15556046
    • van der Meer P, Lipsic E, Henning RH, et al. Erythropoietin improves left ventricular function and coronary flow in an experimental model of ischemia-reperfusion injury. Eur J Heart Fail. 2004;6:853-9.
    • (2004) Eur J Heart Fail , vol.6 , pp. 853-859
    • Van Der Meer, P.1    Lipsic, E.2    Henning, R.H.3
  • 59
    • 24944499366 scopus 로고    scopus 로고
    • Erythropoietin protects the myocardium against reperfusion injury in vitro and in vivo
    • 15944807 1:CAS:528:DC%2BD2MXhtFemur7N 10.1007/s00395-005-0537-4
    • Bullard AJ, Govewalla P, Yellon DM. Erythropoietin protects the myocardium against reperfusion injury in vitro and in vivo. Basic Res Cardiol. 2005;100:397-403.
    • (2005) Basic Res Cardiol , vol.100 , pp. 397-403
    • Bullard, A.J.1    Govewalla, P.2    Yellon, D.M.3
  • 60
    • 46749084187 scopus 로고    scopus 로고
    • Signal mechanism activated by erythropoietin preconditioning and remote renal preconditioning-induced cardioprotection
    • 18528635 1:CAS:528:DC%2BD1cXnslKqsr4%3D 10.1007/s11010-008-9808-3
    • Diwan V, Kant R, Jaggi AS, Singh N, Singh D. Signal mechanism activated by erythropoietin preconditioning and remote renal preconditioning-induced cardioprotection. Mol Cell Biochem. 2008;315:195-201.
    • (2008) Mol Cell Biochem , vol.315 , pp. 195-201
    • Diwan, V.1    Kant, R.2    Jaggi, A.S.3    Singh, N.4    Singh, D.5
  • 61
    • 2442714969 scopus 로고    scopus 로고
    • Cardioprotective effects of erythropoietin in the reperfused ischemic heart: A potential role for cardiac fibroblasts
    • 15020586 1:CAS:528:DC%2BD2cXjvV2nsr8%3D 10.1074/jbc.M314099200
    • Parsa CJ, Kim J, Riel RU, et al. Cardioprotective effects of erythropoietin in the reperfused ischemic heart: a potential role for cardiac fibroblasts. J Biol Chem. 2004;279:20655-62.
    • (2004) J Biol Chem , vol.279 , pp. 20655-20662
    • Parsa, C.J.1    Kim, J.2    Riel, R.U.3
  • 62
    • 25144473718 scopus 로고    scopus 로고
    • Erythropoietin protects the infant heart against ischemia-reperfusion injury by triggering multiple signaling pathways
    • 15611843 1:CAS:528:DC%2BD2MXkslKls74%3D 10.1007/s00395-004-0508-1
    • Rafiee P, Shi Y, Su J, Pritchard Jr KA, Tweddell JS, Baker JE. Erythropoietin protects the infant heart against ischemia-reperfusion injury by triggering multiple signaling pathways. Basic Res Cardiol. 2005;100:187-97.
    • (2005) Basic Res Cardiol , vol.100 , pp. 187-197
    • Rafiee, P.1    Shi, Y.2    Su, J.3    Pritchard, Jr.K.A.4    Tweddell, J.S.5    Baker, J.E.6
  • 63
    • 44249103783 scopus 로고    scopus 로고
    • Limitation of infarct size by erythropoietin is associated with translocation of Akt to the mitochondria after reperfusion
    • 18346168 1:CAS:528:DC%2BD1cXnsVCmu7w%3D 10.1111/j.1440-1681.2008.04925.x
    • Kobayashi H, Miura T, Ishida H, et al. Limitation of infarct size by erythropoietin is associated with translocation of Akt to the mitochondria after reperfusion. Clin Exp Pharmacol Physiol. 2008;35:812-9.
    • (2008) Clin Exp Pharmacol Physiol , vol.35 , pp. 812-819
    • Kobayashi, H.1    Miura, T.2    Ishida, H.3
  • 64
    • 33748121774 scopus 로고    scopus 로고
    • High-dose erythropoietin has no long-term protective effects in sheep with reperfused myocardial infarction
    • 16810073 1:CAS:528:DC%2BD28XmtlGlurw%3D 10.1097/01.fjc.0000211766.59636. 0d
    • Olea FD, Vera Janavel G, De Lorenzi A, et al. High-dose erythropoietin has no long-term protective effects in sheep with reperfused myocardial infarction. J Cardiovasc Pharmacol. 2006;47:736-41.
    • (2006) J Cardiovasc Pharmacol , vol.47 , pp. 736-741
    • Olea, F.D.1    Vera Janavel, G.2    De Lorenzi, A.3
  • 65
    • 24044473759 scopus 로고    scopus 로고
    • Lack of acute cardioprotective effect from preischaemic erythropoietin administration in a porcine coronary occlusion model
    • 16117735 1:CAS:528:DC%2BD2MXhtVGgsL3K 10.1111/j.1475-097X.2005.00626.x
    • Kristensen J, Maeng M, Rehling M, et al. Lack of acute cardioprotective effect from preischaemic erythropoietin administration in a porcine coronary occlusion model. Clin Physiol Funct Imaging. 2005;25:305-10.
    • (2005) Clin Physiol Funct Imaging , vol.25 , pp. 305-310
    • Kristensen, J.1    Maeng, M.2    Rehling, M.3
  • 66
    • 84880288654 scopus 로고    scopus 로고
    • Erythropoietin protects the systolic function of neonatal hearts against ischaemia/reperfusion injury
    • 22564802 10.1093/ejcts/ezs254
    • Vilarinho KA, de Oliveira PP, Saad MJ, et al. Erythropoietin protects the systolic function of neonatal hearts against ischaemia/reperfusion injury. Eur J Cardiothorac Surg. 2013;43:156-62.
    • (2013) Eur J Cardiothorac Surg , vol.43 , pp. 156-162
    • Vilarinho, K.A.1    De Oliveira, P.P.2    Saad, M.J.3
  • 67
    • 77958518157 scopus 로고    scopus 로고
    • A single dose of erythropoietin in ST-elevation myocardial infarction
    • 20802250 1:CAS:528:DC%2BC3cXhsVSlt7jI 10.1093/eurheartj/ehq304
    • Voors AA, Belonje AM, Zijlstra F, et al. A single dose of erythropoietin in ST-elevation myocardial infarction. Eur Heart J. 2010;31:2593-600.
    • (2010) Eur Heart J , vol.31 , pp. 2593-2600
    • Voors, A.A.1    Belonje, A.M.2    Zijlstra, F.3
  • 68
    • 79955877895 scopus 로고    scopus 로고
    • Intravenous erythropoietin in patients with ST-segment elevation myocardial infarction: REVEAL: A randomized controlled trial
    • 21558517 1:CAS:528:DC%2BC3MXlvFGmt70%3D 10.1001/jama.2011.592
    • Najjar SS, Rao SV, Melloni C, et al. Intravenous erythropoietin in patients with ST-segment elevation myocardial infarction: REVEAL: a randomized controlled trial. JAMA. 2011;305:1863-72.
    • (2011) JAMA , vol.305 , pp. 1863-1872
    • Najjar, S.S.1    Rao, S.V.2    Melloni, C.3
  • 69
    • 78349233886 scopus 로고    scopus 로고
    • Erythropoietin prevention trial of coronary restenosis and cardiac remodeling after ST-elevated acute myocardial infarction (EPOC-AMI): A pilot, randomized, placebo-controlled study
    • 20834185 10.1253/circj.CJ-10-0267
    • Taniguchi N, Nakamura T, Sawada T, et al. Erythropoietin prevention trial of coronary restenosis and cardiac remodeling after ST-elevated acute myocardial infarction (EPOC-AMI): a pilot, randomized, placebo-controlled study. Circ J. 2010;74:2365-71.
    • (2010) Circ J , vol.74 , pp. 2365-2371
    • Taniguchi, N.1    Nakamura, T.2    Sawada, T.3
  • 70
    • 77954492825 scopus 로고    scopus 로고
    • Single-dose intravenous administration of recombinant human erythropoietin is a promising treatment for patients with acute myocardial infarction - Randomized controlled pilot trial of EPO/AMI-1 study
    • 20501957 1:CAS:528:DC%2BC3cXpvFans7s%3D 10.1253/circj.CJ-10-0109
    • Ozawa T, Toba K, Suzuki H, et al. Single-dose intravenous administration of recombinant human erythropoietin is a promising treatment for patients with acute myocardial infarction - randomized controlled pilot trial of EPO/AMI-1 study. Circ J. 2010;74:1415-23.
    • (2010) Circ J , vol.74 , pp. 1415-1423
    • Ozawa, T.1    Toba, K.2    Suzuki, H.3
  • 71
    • 79951722690 scopus 로고    scopus 로고
    • High-dose erythropoietin in patients with acute myocardial infarction: A pilot, randomised, placebo-controlled study
    • 19906454 10.1016/j.ijcard.2009.10.028
    • Ferrario M, Arbustini E, Massa M, et al. High-dose erythropoietin in patients with acute myocardial infarction: a pilot, randomised, placebo-controlled study. Int J Cardiol. 2011;147:124-31.
    • (2011) Int J Cardiol , vol.147 , pp. 124-131
    • Ferrario, M.1    Arbustini, E.2    Massa, M.3
  • 72
    • 80052666905 scopus 로고    scopus 로고
    • Effect of erythropoietin as an adjunct to primary percutaneous coronary intervention: A randomised controlled clinical trial
    • 21900585 1:CAS:528:DC%2BC3MXhtlKjtb3M 10.1136/hrt.2011.223867
    • Ludman AJ, Yellon DM, Hasleton J, et al. Effect of erythropoietin as an adjunct to primary percutaneous coronary intervention: a randomised controlled clinical trial. Heart. 2011;97:1560-5.
    • (2011) Heart , vol.97 , pp. 1560-1565
    • Ludman, A.J.1    Yellon, D.M.2    Hasleton, J.3
  • 73
    • 84856547427 scopus 로고    scopus 로고
    • Single high-dose erythropoietin administration immediately after reperfusion in patients with ST-segment elevation myocardial infarction: Results of the erythropoietin in myocardial infarction trial
    • 22305837 1:CAS:528:DC%2BC38XhvVWrur8%3D 10.1016/j.ahj.2011.11.005
    • Prunier F, Biere L, Gilard M, et al. Single high-dose erythropoietin administration immediately after reperfusion in patients with ST-segment elevation myocardial infarction: results of the erythropoietin in myocardial infarction trial. Am Heart J. 2012;163:200-7.
    • (2012) Am Heart J , vol.163 , pp. 200-207
    • Prunier, F.1    Biere, L.2    Gilard, M.3
  • 74
    • 35848934379 scopus 로고    scopus 로고
    • Postconditioning in man
    • 17522975 1:CAS:528:DC%2BD2sXnvFKntL4%3D 10.1007/s10741-007-9033-2
    • Thibault H, Piot C, Ovize M. Postconditioning in man. Heart Fail Rev. 2007;12:245-8.
    • (2007) Heart Fail Rev , vol.12 , pp. 245-248
    • Thibault, H.1    Piot, C.2    Ovize, M.3
  • 75
    • 84860112500 scopus 로고    scopus 로고
    • Pharmacological approaches to reperfusion therapy
    • 22514248 1:CAS:528:DC%2BC38XmtVegt7c%3D 10.1093/cvr/cvs114
    • Morel O, Perret T, Delarche N, et al. Pharmacological approaches to reperfusion therapy. Cardiovasc Res. 2012;94:246-52.
    • (2012) Cardiovasc Res , vol.94 , pp. 246-252
    • Morel, O.1    Perret, T.2    Delarche, N.3
  • 76
    • 80051502724 scopus 로고    scopus 로고
    • The role of comorbidities in cardioprotection
    • 21821527 1:CAS:528:DC%2BC3MXhtFKrurvN 10.1177/1074248411408313
    • Sack MN, Murphy E. The role of comorbidities in cardioprotection. J Cardiovasc Pharmacol Ther. 2011;16:267-72.
    • (2011) J Cardiovasc Pharmacol Ther , vol.16 , pp. 267-272
    • Sack, M.N.1    Murphy, E.2
  • 77
    • 77950350159 scopus 로고    scopus 로고
    • Effects of a protocol of ischemic postconditioning and/or captopril in hearts of normotensive and hypertensive rats
    • 20012872 10.1007/s00395-009-0075-6
    • Penna C, Tullio F, Moro F, Folino A, Merlino A, Pagliaro P. Effects of a protocol of ischemic postconditioning and/or captopril in hearts of normotensive and hypertensive rats. Basic Res Cardiol. 2010;105:181-92.
    • (2010) Basic Res Cardiol , vol.105 , pp. 181-192
    • Penna, C.1    Tullio, F.2    Moro, F.3    Folino, A.4    Merlino, A.5    Pagliaro, P.6
  • 78
    • 79955678054 scopus 로고    scopus 로고
    • Efficacy of cardioprotective 'conditioning' strategies in aging and diabetic cohorts: The co-morbidity conundrum
    • 10.2165/11587190-000000000-00000
    • Przyklenk K. Efficacy of cardioprotective 'conditioning' strategies in aging and diabetic cohorts: the co-morbidity conundrum. Drug Aging. 2011;28:331-43.
    • (2011) Drug Aging , vol.28 , pp. 331-343
    • Przyklenk, K.1
  • 79
    • 40149096222 scopus 로고    scopus 로고
    • Morphine postconditioning protects against reperfusion injury in the isolated rat hearts
    • 18155248 1:CAS:528:DC%2BD1cXjtVeqt7c%3D 10.1016/j.jss.2007.07.020
    • Chen Z, Li T, Zhang B. Morphine postconditioning protects against reperfusion injury in the isolated rat hearts. J Surg Res. 2008;145:287-94.
    • (2008) J Surg Res , vol.145 , pp. 287-294
    • Chen, Z.1    Li, T.2    Zhang, B.3
  • 80
    • 67649600357 scopus 로고    scopus 로고
    • Combined morphine and limb remote ischaemia postconditioning may produce an enhanced cardioprotection
    • 19428190 1:CAS:528:DC%2BD1MXotF2nsbs%3D 10.1016/j.mehy.2009.04.004
    • Xu YC, Xue FS, Liao X, et al. Combined morphine and limb remote ischaemia postconditioning may produce an enhanced cardioprotection. Med Hypotheses. 2009;73:302-5.
    • (2009) Med Hypotheses , vol.73 , pp. 302-305
    • Xu, Y.C.1    Xue, F.S.2    Liao, X.3
  • 81
    • 77950366415 scopus 로고    scopus 로고
    • Simvastatin in contrast to postconditioning reduces infarct size in hyperlipidemic rabbits: Possible role of oxidative/nitrosative stress attenuation
    • 20066537 1:CAS:528:DC%2BC3cXnvFWktg%3D%3D 10.1007/s00395-009-0078-3
    • Iliodromitis EK, Andreadou I, Prokovas E, Zoga A, Farmakis D, Fotopoulou T, et al. Simvastatin in contrast to postconditioning reduces infarct size in hyperlipidemic rabbits: possible role of oxidative/nitrosative stress attenuation. Basic Res Cardiol. 2010;105:193-203.
    • (2010) Basic Res Cardiol , vol.105 , pp. 193-203
    • Iliodromitis, E.K.1    Andreadou, I.2    Prokovas, E.3    Zoga, A.4    Farmakis, D.5    Fotopoulou, T.6
  • 82
    • 44949131820 scopus 로고    scopus 로고
    • Lovastatin interferes with the infarct size-limiting effect of ischemic preconditioning and postconditioning in rat hearts
    • 18359895 1:CAS:528:DC%2BD1cXmtVWnsL8%3D 10.1152/ajpheart.00862.2007
    • Kocsis GF, Pipis J, Fekete V, et al. Lovastatin interferes with the infarct size-limiting effect of ischemic preconditioning and postconditioning in rat hearts. Am J Physiol Heart Circ Physiol. 2008;294:H2406-9.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294 , pp. 2406-2409
    • Kocsis, G.F.1    Pipis, J.2    Fekete, V.3
  • 83
    • 40149108924 scopus 로고    scopus 로고
    • Cardioprotection and kallikrein-kinin system in acute myocardial ischaemia in mice
    • 18307747 1:CAS:528:DC%2BD1cXjvFCjsrg%3D 10.1111/j.1440-1681.2008.04902.x
    • Messadi-Laribi E, Griol-Charhbili V, Gaies E, et al. Cardioprotection and kallikrein-kinin system in acute myocardial ischaemia in mice. Clin Exp Pharmacol Physiol. 2008;35:489-93.
    • (2008) Clin Exp Pharmacol Physiol , vol.35 , pp. 489-493
    • Messadi-Laribi, E.1    Griol-Charhbili, V.2    Gaies, E.3
  • 84
    • 84856702326 scopus 로고    scopus 로고
    • The potential effects of anti-diabetic medications on myocardial ischemia-reperfusion injury
    • 21892746 1:CAS:528:DC%2BC3MXhsFOnsL7L 10.1007/s00395-011-0216-6
    • Ye Y, Perez-Polo JR, Aguilar D, Birnbaum Y. The potential effects of anti-diabetic medications on myocardial ischemia-reperfusion injury. Basic Res Cardiol. 2011;106:925-52.
    • (2011) Basic Res Cardiol , vol.106 , pp. 925-952
    • Ye, Y.1    Perez-Polo, J.R.2    Aguilar, D.3    Birnbaum, Y.4
  • 85
    • 84862284064 scopus 로고    scopus 로고
    • Cardioprotection by clopidogrel in acute ST-elevated myocardial infarction patients: A retrospective analysis
    • 22718009 10.1007/s00395-012-0275-3
    • Roubille F, Lairez O, Mewton N, et al. Cardioprotection by clopidogrel in acute ST-elevated myocardial infarction patients: a retrospective analysis. Basic Res Cardiol. 2012;107:275.
    • (2012) Basic Res Cardiol , vol.107 , pp. 275
    • Roubille, F.1    Lairez, O.2    Mewton, N.3
  • 86
    • 84878284743 scopus 로고    scopus 로고
    • Cardioprotection - Time to take into account clinical complexity: The case of antiplatelet agents
    • 23354515 10.1007/s10557-013-6443-3
    • Roubille F, Tardif JC. Cardioprotection - time to take into account clinical complexity: the case of antiplatelet agents. Cardiovasc Drugs Ther. 2013;27:105-7.
    • (2013) Cardiovasc Drugs Ther , vol.27 , pp. 105-107
    • Roubille, F.1    Tardif, J.C.2
  • 87
    • 34347212063 scopus 로고    scopus 로고
    • Darbepoetin alfa protects the rat heart against infarction: Dose-response, phase of action, and mechanisms
    • 17577097 1:CAS:528:DC%2BD2sXmsFOisrs%3D 10.1097/FJC.0b013e318040cf81
    • Baker JE, Kozik D, Hsu AK, Fu X, Tweddell JS, Gross GJ. Darbepoetin alfa protects the rat heart against infarction: dose-response, phase of action, and mechanisms. J Cardiovasc Pharmacol. 2007;49:337-45.
    • (2007) J Cardiovasc Pharmacol , vol.49 , pp. 337-345
    • Baker, J.E.1    Kozik, D.2    Hsu, A.K.3    Fu, X.4    Tweddell, J.S.5    Gross, G.J.6
  • 88
    • 79957445321 scopus 로고    scopus 로고
    • The effect of intravenous administration of erythropoietin on the infarct size in primary percutaneous coronary intervention
    • 20199815 10.1016/j.ijcard.2010.02.002
    • Suh JW, Chung WY, Kim YS, et al. The effect of intravenous administration of erythropoietin on the infarct size in primary percutaneous coronary intervention. Int J Cardiol. 2011;149:216-20.
    • (2011) Int J Cardiol , vol.149 , pp. 216-220
    • Suh, J.W.1    Chung, W.Y.2    Kim, Y.S.3
  • 89
    • 1542298950 scopus 로고    scopus 로고
    • Postconditioning attenuates myocardial ischemia-reperfusion injury by inhibiting events in the early minutes of reperfusion
    • 15023554 1:CAS:528:DC%2BD2cXitFejuro%3D 10.1016/j.cardiores.2004.01.006
    • Kin H, Zhao ZQ, Sun HY, et al. Postconditioning attenuates myocardial ischemia-reperfusion injury by inhibiting events in the early minutes of reperfusion. Cardiovasc Res. 2004;62:74-85.
    • (2004) Cardiovasc Res , vol.62 , pp. 74-85
    • Kin, H.1    Zhao, Z.Q.2    Sun, H.Y.3
  • 90
    • 34548448546 scopus 로고    scopus 로고
    • Inhibition of mitochondrial permeability transition improves functional recovery and reduces mortality following acute myocardial infarction in mice
    • 17557911 1:CAS:528:DC%2BD2sXhtVOqtrrO 10.1152/ajpheart.01378.2006
    • Gomez L, Thibault H, Gharib A, et al. Inhibition of mitochondrial permeability transition improves functional recovery and reduces mortality following acute myocardial infarction in mice. Am J Physiol Heart Circ Physiol. 2007;293:H1654-61.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293 , pp. 1654-1661
    • Gomez, L.1    Thibault, H.2    Gharib, A.3
  • 91
    • 44449133771 scopus 로고    scopus 로고
    • Inhibition of GSK3beta by postconditioning is required to prevent opening of the mitochondrial permeability transition pore during reperfusion
    • 18490522 1:CAS:528:DC%2BD1cXmvFegu74%3D 10.1161/CIRCULATIONAHA.107.755066
    • Gomez L, Paillard M, Thibault H, Derumeaux G, Ovize M. Inhibition of GSK3beta by postconditioning is required to prevent opening of the mitochondrial permeability transition pore during reperfusion. Circulation. 2008;117:2761-8.
    • (2008) Circulation , vol.117 , pp. 2761-2768
    • Gomez, L.1    Paillard, M.2    Thibault, H.3    Derumeaux, G.4    Ovize, M.5
  • 92
    • 84860010915 scopus 로고    scopus 로고
    • Did clinical trials in which erythropoietin failed to reduce acute myocardial infarct size miss a narrow therapeutic window?
    • 22529941 1:CAS:528:DC%2BC38XmsVGgurc%3D 10.1371/journal.pone.0034819
    • Talan MI, Ahmet I, Lakatta EG. Did clinical trials in which erythropoietin failed to reduce acute myocardial infarct size miss a narrow therapeutic window? PLoS One. 2012;7:e34819.
    • (2012) PLoS One , vol.7 , pp. 34819
    • Talan, M.I.1    Ahmet, I.2    Lakatta, E.G.3
  • 93
    • 12344317925 scopus 로고    scopus 로고
    • Postconditioning inhibits mitochondrial permeability transition
    • 15642769 1:CAS:528:DC%2BD2MXit1Ggtg%3D%3D 10.1161/01.CIR.0000151290. 04952.3B
    • Argaud L, Gateau-Roesch O, Raisky O, Loufouat J, Robert D, Ovize M. Postconditioning inhibits mitochondrial permeability transition. Circulation. 2005;111:194-7.
    • (2005) Circulation , vol.111 , pp. 194-197
    • Argaud, L.1    Gateau-Roesch, O.2    Raisky, O.3    Loufouat, J.4    Robert, D.5    Ovize, M.6
  • 94
    • 33947547423 scopus 로고    scopus 로고
    • Prolonged transient acidosis during early reperfusion contributes to the cardioprotective effects of postconditioning
    • 17208997 1:CAS:528:DC%2BD2sXks1KisLY%3D 10.1152/ajpheart.01051.2006
    • Fujita M, Asanuma H, Hirata A, et al. Prolonged transient acidosis during early reperfusion contributes to the cardioprotective effects of postconditioning. Am J Physiol Heart Circ Physiol. 2007;292:H2004-8.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292 , pp. 2004-2008
    • Fujita, M.1    Asanuma, H.2    Hirata, A.3
  • 95
    • 80052968092 scopus 로고    scopus 로고
    • Delayed postconditioning in the mouse heart in vivo
    • 21875909 10.1161/CIRCULATIONAHA.111.031864
    • Roubille F, Franck-Miclo A, Covinhes A, et al. Delayed postconditioning in the mouse heart in vivo. Circulation. 2011;124:1330-6.
    • (2011) Circulation , vol.124 , pp. 1330-1336
    • Roubille, F.1    Franck-Miclo, A.2    Covinhes, A.3
  • 96
    • 55849112648 scopus 로고    scopus 로고
    • Acute effects of "delayed postconditioning" with periodic acceleration after asphyxia induced shock in pigs
    • 18596578 10.1203/PDR.0b013e318183f147
    • Adams JA, Bassuk JA, Arias J, et al. Acute effects of "delayed postconditioning" with periodic acceleration after asphyxia induced shock in pigs. Pediatr Res. 2008;64:533-7.
    • (2008) Pediatr Res , vol.64 , pp. 533-537
    • Adams, J.A.1    Bassuk, J.A.2    Arias, J.3
  • 97
    • 57549115569 scopus 로고    scopus 로고
    • Delayed postconditioning protects against focal ischemic brain injury in rats
    • 19066627 10.1371/journal.pone.0003851 1:CAS:528:DC%2BD1MXmslSm
    • Ren C, Gao X, Niu G, Yan Z, Chen X, Zhao H. Delayed postconditioning protects against focal ischemic brain injury in rats. PLoS One. 2008;3:e3851.
    • (2008) PLoS One , vol.3 , pp. 3851
    • Ren, C.1    Gao, X.2    Niu, G.3    Yan, Z.4    Chen, X.5    Zhao, H.6
  • 98
    • 70349656301 scopus 로고    scopus 로고
    • Delayed hypoxic postconditioning protects against cerebral ischemia in the mouse
    • 19628803 10.1161/STROKEAHA.109.557314
    • Leconte C, Tixier E, Freret T, et al. Delayed hypoxic postconditioning protects against cerebral ischemia in the mouse. Stroke. 2009;40:3349-55.
    • (2009) Stroke , vol.40 , pp. 3349-3355
    • Leconte, C.1    Tixier, E.2    Freret, T.3
  • 99
    • 4644227714 scopus 로고    scopus 로고
    • Timing of erythropoietin treatment for cardioprotection in ischemia/reperfusion
    • 15454856 1:CAS:528:DC%2BD2cXnvFamsbY%3D 10.1097/01.fjc.0000140209.04675. c3
    • Lipsic E, van der Meer P, Henning RH, et al. Timing of erythropoietin treatment for cardioprotection in ischemia/reperfusion. J Cardiovasc Pharmacol. 2004;44:473-9.
    • (2004) J Cardiovasc Pharmacol , vol.44 , pp. 473-479
    • Lipsic, E.1    Van Der Meer, P.2    Henning, R.H.3
  • 100
    • 28844443403 scopus 로고    scopus 로고
    • Cardioprotection by recombinant human erythropoietin following acute experimental myocardial infarction: Dose response and therapeutic window
    • 16187008 1:CAS:528:DC%2BD2MXhtlSjtb7M 10.1007/s10557-005-3189-6
    • Moon C, Krawczyk M, Paik D, Lakatta EG, Talan MI. Cardioprotection by recombinant human erythropoietin following acute experimental myocardial infarction: dose response and therapeutic window. Cardiovasc Drugs Ther. 2005;19:243-50.
    • (2005) Cardiovasc Drugs Ther , vol.19 , pp. 243-250
    • Moon, C.1    Krawczyk, M.2    Paik, D.3    Lakatta, E.G.4    Talan, M.I.5
  • 101
    • 84864301163 scopus 로고    scopus 로고
    • Remote ischaemic pre- and delayed postconditioning - Similar degree of cardioprotection but distinct mechanisms
    • 22427438 1:CAS:528:DC%2BC38XhsVCjt7%2FE 10.1113/expphysiol.2012.064923
    • Basalay M, Barsukevich V, Mastitskaya S, et al. Remote ischaemic pre- and delayed postconditioning - similar degree of cardioprotection but distinct mechanisms. Exp Physiol. 2012;97:908-17.
    • (2012) Exp Physiol , vol.97 , pp. 908-917
    • Basalay, M.1    Barsukevich, V.2    Mastitskaya, S.3
  • 102
    • 33745025709 scopus 로고    scopus 로고
    • A single bolus of a long-acting erythropoietin analogue darbepoetin alfa in patients with acute myocardial infarction: A randomized feasibility and safety study
    • 16761193 1:CAS:528:DC%2BD28XlsVCiu74%3D 10.1007/s10557-006-7680-5
    • Lipsic E, van der Meer P, Voors AA, et al. A single bolus of a long-acting erythropoietin analogue darbepoetin alfa in patients with acute myocardial infarction: a randomized feasibility and safety study. Cardiovasc Drugs Ther. 2006;20:135-41.
    • (2006) Cardiovasc Drugs Ther , vol.20 , pp. 135-141
    • Lipsic, E.1    Van Der Meer, P.2    Voors, A.A.3
  • 103
    • 78349287458 scopus 로고    scopus 로고
    • Erythropoietin in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: A randomized, double-blind trial
    • 20736448 1:CAS:528:DC%2BC3cXhsFaiur%2FJ 10.1161/CIRCINTERVENTIONS.109. 904425
    • Ott I, Schulz S, Mehilli J, et al. Erythropoietin in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomized, double-blind trial. Circ Cardiovasc Interv. 2010;3:408-13.
    • (2010) Circ Cardiovasc Interv , vol.3 , pp. 408-413
    • Ott, I.1    Schulz, S.2    Mehilli, J.3
  • 104
    • 84876262969 scopus 로고    scopus 로고
    • Intracoronary administration of darbepoetin-alpha at onset of reperfusion in acute myocardial infarction: Results of the randomized Intra-Co-EpoMI Trial
    • 23582675 10.1016/j.acvd.2012.12.001
    • Roubille F, Micheau A, Combes S, Piot C. Intracoronary administration of darbepoetin-alpha at onset of reperfusion in acute myocardial infarction: results of the randomized Intra-Co-EpoMI Trial. Arch Cardiovasc Dis. 2013;106:135-45.
    • (2013) Arch Cardiovasc Dis , vol.106 , pp. 135-145
    • Roubille, F.1    Micheau, A.2    Combes, S.3    Piot, C.4
  • 105
    • 77954879762 scopus 로고    scopus 로고
    • Darbepoetin-mediated cardioprotection after myocardial infarction involves multiple mechanisms independent of erythropoietin receptor-common beta-chain heteroreceptor
    • 1:CAS:528:DC%2BC3cXht1KjurrN 10.1111/j.1476-5381.2010.00876.x
    • Kanellakis P, Pomilio G, Agrotis A, Gao X, Du XJ, Curtis D, et al. Darbepoetin-mediated cardioprotection after myocardial infarction involves multiple mechanisms independent of erythropoietin receptor-common beta-chain heteroreceptor. Brit J Pharmacol. 2010;160:2085-96.
    • (2010) Brit J Pharmacol , vol.160 , pp. 2085-2096
    • Kanellakis, P.1    Pomilio, G.2    Agrotis, A.3    Gao, X.4    Du, X.J.5    Curtis, D.6
  • 106
    • 80052169578 scopus 로고    scopus 로고
    • Darbepoetin improves endothelial function and increases circulating endothelial progenitor cell number in patients with coronary artery disease
    • 21719555 1:CAS:528:DC%2BC3MXht12jt7vF 10.1136/hrt.2010.220798
    • Mueller C, Wodack K, Twelker K, Werner N, Custodis F, Nickenig G. Darbepoetin improves endothelial function and increases circulating endothelial progenitor cell number in patients with coronary artery disease. Heart. 2011;97:1474-8.
    • (2011) Heart , vol.97 , pp. 1474-1478
    • Mueller, C.1    Wodack, K.2    Twelker, K.3    Werner, N.4    Custodis, F.5    Nickenig, G.6
  • 107
    • 84856400042 scopus 로고    scopus 로고
    • Darbepoetin enhances endothelium-dependent vasomotor function in patients with stable coronary artery disease only after preceding ischaemia/reperfusion
    • 21966999 1:CAS:528:DC%2BC3MXhsFylu7fK 10.1042/CS20110369
    • Tilling L, Hunt J, Donald A, Clapp B, Chowienczyk P. Darbepoetin enhances endothelium-dependent vasomotor function in patients with stable coronary artery disease only after preceding ischaemia/reperfusion. Clin Sci. 2012;122:329-36.
    • (2012) Clin Sci , vol.122 , pp. 329-336
    • Tilling, L.1    Hunt, J.2    Donald, A.3    Clapp, B.4    Chowienczyk, P.5
  • 108
    • 66849138375 scopus 로고    scopus 로고
    • Arterial hypertension induced by erythropoietin and erythropoiesis- stimulating agents (ESA)
    • 19218474 1:CAS:528:DC%2BD1MXjslagurY%3D 10.2215/CJN.05040908
    • Krapf R, Hulter HN. Arterial hypertension induced by erythropoietin and erythropoiesis-stimulating agents (ESA). Clin J Am Soc Nephrol. 2009;4:470-80.
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 470-480
    • Krapf, R.1    Hulter, H.N.2
  • 109
    • 64749102040 scopus 로고    scopus 로고
    • Thrombocytosis in EPO-treated dialysis patients may be mediated by EPO rather than iron deficiency
    • 19303685 10.1053/j.ajkd.2008.12.030
    • Vaziri ND. Thrombocytosis in EPO-treated dialysis patients may be mediated by EPO rather than iron deficiency. Am J Kidney Dis. 2009;53:733-6.
    • (2009) Am J Kidney Dis , vol.53 , pp. 733-736
    • Vaziri, N.D.1
  • 110
    • 34047202482 scopus 로고    scopus 로고
    • EPO tecting the endothelium
    • 1:CAS:528:DC%2BD2sXjs12nt7s%3D 10.1038/sj.bjp.0707162
    • Peterson TE, Katusic ZS. EPO tecting the endothelium. Brit J Pharmacol. 2007;150:823-5.
    • (2007) Brit J Pharmacol , vol.150 , pp. 823-825
    • Peterson, T.E.1    Katusic, Z.S.2
  • 111
    • 84862578545 scopus 로고    scopus 로고
    • Erythropoietin: A future therapy for failing hearts?
    • 22052470 1:CAS:528:DC%2BC38Xls1ShtLc%3D 10.1007/s10741-011-9288-5
    • Tilling L, Clapp B. Erythropoietin: a future therapy for failing hearts? Heart Fail Rev. 2012;17:475-83.
    • (2012) Heart Fail Rev , vol.17 , pp. 475-483
    • Tilling, L.1    Clapp, B.2
  • 113
    • 0036705708 scopus 로고    scopus 로고
    • Erythropoietin therapy for acute stroke is both safe and beneficial
    • 12435860 1:CAS:528:DC%2BD38XovVWhsrg%3D
    • Ehrenreich H, Hasselblatt M, Dembowski C, et al. Erythropoietin therapy for acute stroke is both safe and beneficial. Mol Med. 2002;8:495-505.
    • (2002) Mol Med , vol.8 , pp. 495-505
    • Ehrenreich, H.1    Hasselblatt, M.2    Dembowski, C.3
  • 114
    • 78650517036 scopus 로고    scopus 로고
    • Recombinant human erythropoietin delays loss of gray matter in chronic schizophrenia
    • 20479759 1:CAS:528:DC%2BC3cXhsF2msbfO 10.1038/mp.2010.51
    • Wustenberg T, Begemann M, Bartels C, et al. Recombinant human erythropoietin delays loss of gray matter in chronic schizophrenia. Mol Psychiatry. 2011;16:26-36.
    • (2011) Mol Psychiatry , vol.16 , pp. 26-36
    • Wustenberg, T.1    Begemann, M.2    Bartels, C.3
  • 115
    • 74049110427 scopus 로고    scopus 로고
    • Erythropoiesis stimulating agent administration improves survival after severe traumatic brain injury: A matched case control study
    • 19779323 10.1097/SLA.0b013e3181b844fa
    • Talving P, Lustenberger T, Kobayashi L, et al. Erythropoiesis stimulating agent administration improves survival after severe traumatic brain injury: a matched case control study. Ann Surg. 2010;251:1-4.
    • (2010) Ann Surg , vol.251 , pp. 1-4
    • Talving, P.1    Lustenberger, T.2    Kobayashi, L.3
  • 116
    • 80052865410 scopus 로고    scopus 로고
    • Renovascular protective effects of erythropoietin in patients with chronic kidney disease
    • 21921371 1:CAS:528:DC%2BC38XhsVynsLjN 10.2169/internalmedicine.50.5145
    • Fujiwara N, Nakamura T, Sato E, et al. Renovascular protective effects of erythropoietin in patients with chronic kidney disease. Intern Med. 2011;50:1929-34.
    • (2011) Intern Med , vol.50 , pp. 1929-1934
    • Fujiwara, N.1    Nakamura, T.2    Sato, E.3
  • 117
    • 84876072034 scopus 로고    scopus 로고
    • The nonhematopoietic effects of erythropoietin in skin regeneration and repair: From basic research to clinical use
    • 22430919 1:CAS:528:DC%2BC3sXlvVyrsb8%3D 10.1002/med.21259
    • Sorg H, Harder Y, Krueger C, Reimers K, Vogt PM. The nonhematopoietic effects of erythropoietin in skin regeneration and repair: from basic research to clinical use. Med Res Rev. 2013;33:637-64.
    • (2013) Med Res Rev , vol.33 , pp. 637-664
    • Sorg, H.1    Harder, Y.2    Krueger, C.3    Reimers, K.4    Vogt, P.M.5
  • 118
    • 70949095435 scopus 로고    scopus 로고
    • Recombinant human erythropoietin in the treatment of acute ischemic stroke
    • 19834012 1:CAS:528:DC%2BD1MXhsValtbrK 10.1161/STROKEAHA.109.564872
    • Ehrenreich H, Weissenborn K, Prange H, et al. Recombinant human erythropoietin in the treatment of acute ischemic stroke. Stroke. 2009;40:e647-56.
    • (2009) Stroke , vol.40 , pp. 647-656
    • Ehrenreich, H.1    Weissenborn, K.2    Prange, H.3
  • 119
    • 84859886939 scopus 로고    scopus 로고
    • Neuroprotection with an erythropoietin mimetic peptide (pHBSP) in a model of mild traumatic brain injury complicated by hemorrhagic shock
    • 21545288 10.1089/neu.2011.1827
    • Robertson CS, Cherian L, Shah M, et al. Neuroprotection with an erythropoietin mimetic peptide (pHBSP) in a model of mild traumatic brain injury complicated by hemorrhagic shock. J Neurotrauma. 2012;29:1156-66.
    • (2012) J Neurotrauma , vol.29 , pp. 1156-1166
    • Robertson, C.S.1    Cherian, L.2    Shah, M.3
  • 120
    • 77957097611 scopus 로고    scopus 로고
    • Neuroprotective properties of a novel, non-haematopoietic agonist of the erythropoietin receptor
    • 20435631 10.1093/brain/awq101
    • Pankratova S, Kiryushko D, Sonn K, et al. Neuroprotective properties of a novel, non-haematopoietic agonist of the erythropoietin receptor. Brain. 2010;133:2281-94.
    • (2010) Brain , vol.133 , pp. 2281-2294
    • Pankratova, S.1    Kiryushko, D.2    Sonn, K.3
  • 121
    • 77951570712 scopus 로고    scopus 로고
    • Non-erythropoietic tissue-protective peptides derived from erythropoietin: WO2009094172
    • 20192905 1:CAS:528:DC%2BC3cXltlWhtrc%3D 10.1517/13543771003627464
    • Dumont F, Bischoff P. Non-erythropoietic tissue-protective peptides derived from erythropoietin: WO2009094172. Expert Opin Ther Pat. 2010;20:715-23.
    • (2010) Expert Opin Ther Pat , vol.20 , pp. 715-723
    • Dumont, F.1    Bischoff, P.2
  • 122
    • 84864286682 scopus 로고    scopus 로고
    • Effect of erythropoiesis-stimulating agents in acute ST-segment elevation myocardial infarction: A systematic review
    • 22086550 1:CAS:528:DC%2BC38XmtFaru7k%3D 10.1007/s00228-011-1160-y
    • Li J, Xu H, Gao Q, Wen Y. Effect of erythropoiesis-stimulating agents in acute ST-segment elevation myocardial infarction: a systematic review. Eur J Clin Pharmacol. 2012;68:469-77.
    • (2012) Eur J Clin Pharmacol , vol.68 , pp. 469-477
    • Li, J.1    Xu, H.2    Gao, Q.3    Wen, Y.4
  • 123
    • 84867149681 scopus 로고    scopus 로고
    • The additive effects of ischemic postconditioning and cyclosporine-A on nitric oxide activity and functions of diabetic myocardium injured by ischemia/reperfusion
    • 21828282 1:CAS:528:DC%2BC38Xpt1yis7s%3D 10.1177/1074248411416118
    • Badalzadeh R, Mohammadi M, Najafi M, Ahmadiasl N, Farajnia S, Ebrahimi H. The additive effects of ischemic postconditioning and cyclosporine-A on nitric oxide activity and functions of diabetic myocardium injured by ischemia/reperfusion. J Cardiovasc Pharmacol Ther. 2012;17:181-9.
    • (2012) J Cardiovasc Pharmacol Ther , vol.17 , pp. 181-189
    • Badalzadeh, R.1    Mohammadi, M.2    Najafi, M.3    Ahmadiasl, N.4    Farajnia, S.5    Ebrahimi, H.6
  • 124
    • 66249141182 scopus 로고    scopus 로고
    • Simultaneous administration of insulin-like growth factor-1 and darbepoetin alfa protects the rat myocardium against myocardial infarction and enhances angiogenesis
    • 20443814 1:CAS:528:DC%2BD1cXpt1Gnsb4%3D 10.1111/j.1752-8062.2008.00008.x
    • Boucher M, Pesant S, Lei YH, et al. Simultaneous administration of insulin-like growth factor-1 and darbepoetin alfa protects the rat myocardium against myocardial infarction and enhances angiogenesis. Clin Transl Sci. 2008;1:13-20.
    • (2008) Clin Transl Sci , vol.1 , pp. 13-20
    • Boucher, M.1    Pesant, S.2    Lei, Y.H.3
  • 125
    • 78649320661 scopus 로고    scopus 로고
    • Translating novel strategies for cardioprotection: The Hatter Workshop Recommendations
    • 20865418 10.1007/s00395-010-0121-4
    • Hausenloy DJ, Baxter G, Bell R, et al. Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations. Basic Res Cardiol. 2010;105:677-86.
    • (2010) Basic Res Cardiol , vol.105 , pp. 677-686
    • Hausenloy, D.J.1    Baxter, G.2    Bell, R.3
  • 126
    • 0036384462 scopus 로고    scopus 로고
    • Erythropoietin and VEGF exhibit equal angiogenic potential
    • 12204656 1:CAS:528:DC%2BD38XmsV2ksrc%3D 10.1006/mvre.2002.2426
    • Jaquet K, Krause K, Tawakol-Khodai M, Geidel S, Kuck KH. Erythropoietin and VEGF exhibit equal angiogenic potential. Microvasc Res. 2002;64:326-33.
    • (2002) Microvasc Res , vol.64 , pp. 326-333
    • Jaquet, K.1    Krause, K.2    Tawakol-Khodai, M.3    Geidel, S.4    Kuck, K.H.5
  • 127
    • 79961151865 scopus 로고    scopus 로고
    • EPO and super-EPO: Erythropoietins direct neoangiogenesis by cardiac progenitor cells
    • 21816360 1:CAS:528:DC%2BC3MXpvFGit7g%3D 10.1016/j.stem.2011.07.008
    • Schneider MD. EPO and super-EPO: erythropoietins direct neoangiogenesis by cardiac progenitor cells. Cell Stem Cell. 2011;9:95-6.
    • (2011) Cell Stem Cell , vol.9 , pp. 95-96
    • Schneider, M.D.1
  • 128
    • 77952599541 scopus 로고    scopus 로고
    • Speckle tracking imaging improves in vivo assessment of EPO-induced myocardial salvage early after ischemia-reperfusion in rats
    • 20363897 1:CAS:528:DC%2BC3cXnslCgtrc%3D 10.1152/ajpheart.01058.2009
    • Treguer F, Donal E, Tamareille S, et al. Speckle tracking imaging improves in vivo assessment of EPO-induced myocardial salvage early after ischemia-reperfusion in rats. Am J Physiol Heart Circ Physiol. 2010;298:H1679-86.
    • (2010) Am J Physiol Heart Circ Physiol , vol.298 , pp. 1679-1686
    • Treguer, F.1    Donal, E.2    Tamareille, S.3
  • 129
    • 84863681324 scopus 로고    scopus 로고
    • The effect of erythropoietin on platelet and endothelial activation markers: A prospective trial in healthy volunteers
    • 22098110 1:CAS:528:DC%2BC38XpvFelu7o%3D 10.3109/09537104.2011.631621
    • Heinisch BB, Vcelar B, Kapiotis S, et al. The effect of erythropoietin on platelet and endothelial activation markers: a prospective trial in healthy volunteers. Platelets. 2012;23:352-8.
    • (2012) Platelets , vol.23 , pp. 352-358
    • Heinisch, B.B.1    Vcelar, B.2    Kapiotis, S.3
  • 130
    • 0036798849 scopus 로고    scopus 로고
    • Erythropoietin triggers a signaling pathway in endothelial cells and increases the thrombogenicity of their extracellular matrices in vitro
    • 12362243
    • Fuste B, Serradell M, Escolar G, et al. Erythropoietin triggers a signaling pathway in endothelial cells and increases the thrombogenicity of their extracellular matrices in vitro. Thromb Haemost. 2002;88:678-85.
    • (2002) Thromb Haemost , vol.88 , pp. 678-685
    • Fuste, B.1    Serradell, M.2    Escolar, G.3
  • 131
    • 0034192225 scopus 로고    scopus 로고
    • Effects of erythropoietin on platelet reactivity and thrombopoiesis in humans
    • 10779449 1:CAS:528:DC%2BD3cXivVaqs7s%3D
    • Stohlawetz PJ, Dzirlo L, Hergovich N, et al. Effects of erythropoietin on platelet reactivity and thrombopoiesis in humans. Blood. 2000;95:2983-9.
    • (2000) Blood , vol.95 , pp. 2983-2989
    • Stohlawetz, P.J.1    Dzirlo, L.2    Hergovich, N.3
  • 132
    • 0034056788 scopus 로고    scopus 로고
    • Erythropoietin and arterial hypertension
    • 10746808 1:CAS:528:DC%2BD3MXhsVCrsLg%3D
    • Luft FC. Erythropoietin and arterial hypertension. Clin Nephrol. 2000;53 Suppl 1:S61-4.
    • (2000) Clin Nephrol , vol.53 , Issue.SUPPL. 1 , pp. 61-64
    • Luft, F.C.1
  • 133
    • 0032962029 scopus 로고    scopus 로고
    • Mechanism of erythropoietin-induced hypertension
    • 10213636 1:CAS:528:DyaK1MXjtVWqsbk%3D 10.1016/S0272-6386(99)70413-0
    • Vaziri ND. Mechanism of erythropoietin-induced hypertension. Am J Kidney Dis. 1999;33:821-8.
    • (1999) Am J Kidney Dis , vol.33 , pp. 821-828
    • Vaziri, N.D.1
  • 134
    • 79955534586 scopus 로고    scopus 로고
    • Acute erythropoietin cardioprotection is mediated by endothelial response
    • 21347618 1:CAS:528:DC%2BC3MXkt12rtb4%3D 10.1007/s00395-011-0158-z
    • Teng R, Calvert JW, Sibmooh N, et al. Acute erythropoietin cardioprotection is mediated by endothelial response. Basic Res Cardiol. 2011;106:343-54.
    • (2011) Basic Res Cardiol , vol.106 , pp. 343-354
    • Teng, R.1    Calvert, J.W.2    Sibmooh, N.3
  • 135
    • 33645210680 scopus 로고    scopus 로고
    • Mechanism of the cardioprotection of rhEPO pretreatment on suppressing the inflammatory response in ischemia-reperfusion
    • 16336978 1:CAS:528:DC%2BD28XivVOgsb0%3D 10.1016/j.lfs.2005.09.053
    • Liu X, Xie W, Liu P, Duan M, Jia Z, Li W, et al. Mechanism of the cardioprotection of rhEPO pretreatment on suppressing the inflammatory response in ischemia-reperfusion. Life Sci. 2006;78:2255-64.
    • (2006) Life Sci , vol.78 , pp. 2255-2264
    • Liu, X.1    Xie, W.2    Liu, P.3    Duan, M.4    Jia, Z.5    Li, W.6
  • 136
    • 74049093676 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor-mediated upregulation of calcineurin activity underlies impairment of cardioprotective signaling in diabetic hearts
    • 19910577 1:CAS:528:DC%2BD1MXhs1aqt7bE 10.1161/CIRCRESAHA.109.205385
    • Hotta H, Miura T, Miki T, et al. Angiotensin II type 1 receptor-mediated upregulation of calcineurin activity underlies impairment of cardioprotective signaling in diabetic hearts. Circ Res. 2010;106:129-32.
    • (2010) Circ Res , vol.106 , pp. 129-132
    • Hotta, H.1    Miura, T.2    Miki, T.3
  • 137
    • 72249101933 scopus 로고    scopus 로고
    • Myocardial reperfusion injury management: Erythropoietin compared with postconditioning
    • 19617412 1:CAS:528:DC%2BD1MXhsFOltLjL 10.1152/ajpheart.00472.2009
    • Tamareille S, Ghaboura N, Treguer F, et al. Myocardial reperfusion injury management: erythropoietin compared with postconditioning. Am J Physiol Heart Circ Physiol. 2009;297:H2035-43.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297 , pp. 2035-2043
    • Tamareille, S.1    Ghaboura, N.2    Treguer, F.3
  • 138
    • 77953675237 scopus 로고    scopus 로고
    • Recombinant human erythropoietin pretreatment attenuates heart ischemia-reperfusion injury in rats by suppressing the systemic inflammatory response
    • 20620481 1:CAS:528:DC%2BC3cXotVahtLs%3D 10.1016/j.transproceed.2009.11. 050
    • Shen Y, Wang Y, Li D, et al. Recombinant human erythropoietin pretreatment attenuates heart ischemia-reperfusion injury in rats by suppressing the systemic inflammatory response. Transplant Proc. 2010;42:1595-7.
    • (2010) Transplant Proc , vol.42 , pp. 1595-1597
    • Shen, Y.1    Wang, Y.2    Li, D.3
  • 139
    • 20044375608 scopus 로고    scopus 로고
    • Erythropoietin just before reperfusion reduces both lethal arrhythmias and infarct size via the phosphatidylinositol-3 kinase-dependent pathway in canine hearts
    • 15883754 1:CAS:528:DC%2BD2MXjvF2lsrg%3D 10.1007/s10557-005-6895-1
    • Hirata A, Minamino T, Asanuma H, et al. Erythropoietin just before reperfusion reduces both lethal arrhythmias and infarct size via the phosphatidylinositol-3 kinase-dependent pathway in canine hearts. Cardiovasc Drugs Ther. 2005;19:33-40.
    • (2005) Cardiovasc Drugs Ther , vol.19 , pp. 33-40
    • Hirata, A.1    Minamino, T.2    Asanuma, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.