메뉴 건너뛰기




Volumn 17, Issue 3, 2012, Pages 475-483

Erythropoietin: A future therapy for failing hearts?

Author keywords

Erythropoietin; Heart failure; Ischaemia; Signalling

Indexed keywords

ANTIANEMIC AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ERYTHROPOIETIN; ERYTHROPOIETIN BETA; HEMOGLOBIN; IRON; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; PLACEBO; RECOMBINANT ERYTHROPOIETIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 84862578545     PISSN: 13824147     EISSN: 15737322     Source Type: Journal    
DOI: 10.1007/s10741-011-9288-5     Document Type: Review
Times cited : (4)

References (65)
  • 1
    • 84862552729 scopus 로고    scopus 로고
    • National Heart Failure Audit
    • The NHS Information Centre, National Heart Failure Audit 2010
    • (2010) The NHS Information Centre
  • 2
    • 77649126524 scopus 로고    scopus 로고
    • Heart association heart disease and stroke statistics-2010 update: A report from the American Heart Association
    • Lloyd-Jones D et al (2010) Heart association heart disease and stroke statistics-2010 update: a report from the American Heart Association. Circulation 121:e46-e215
    • (2010) Circulation , vol.121
    • Lloyd-Jones, D.1
  • 3
    • 1042286928 scopus 로고    scopus 로고
    • The imbalance between oxygen demand and supply as a potential mechanism in the pathophysiology of heart failure: The role of microvascular growth and abnormalities
    • de Boer RA et al (2003) The imbalance between oxygen demand and supply as a potential mechanism in the pathophysiology of heart failure: the role of microvascular growth and abnormalities. Microcirculation 10:113-126
    • (2003) Microcirculation , vol.10 , pp. 113-126
    • De Boer, R.A.1
  • 4
    • 33745459564 scopus 로고    scopus 로고
    • Hemoglobin level, chronic kidney disease, and the risks of death and hospitalization in adults with chronic heart failure: The Anemia in Chronic Heart Failure: Outcomes and Resource Utilization (ANCHOR) Study
    • Go AS et al (2006) Hemoglobin level, chronic kidney disease, and the risks of death and hospitalization in adults with chronic heart failure: the Anemia in Chronic Heart Failure: Outcomes and Resource Utilization (ANCHOR) Study. Circulation 113 (23):2713-2723
    • (2006) Circulation , vol.113 , Issue.23 , pp. 2713-2723
    • Go, A.S.1
  • 5
    • 49849088979 scopus 로고    scopus 로고
    • Anemia and mortality in heart failure patients a systematic review and meta-analysis
    • Groenveld HF et al (2008) Anemia and mortality in heart failure patients a systematic review and meta-analysis. J Am Coll Cardiol 52 (10):818-827
    • (2008) J Am Coll Cardiol , vol.52 , Issue.10 , pp. 818-827
    • Groenveld, H.F.1
  • 6
    • 33748438999 scopus 로고    scopus 로고
    • Intravenous iron alone for the treatment of anemia in patients with chronic heart failure
    • Bolger AP et al (2006) Intravenous iron alone for the treatment of anemia in patients with chronic heart failure. J Am Coll Cardiol 48:1225-1227
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1225-1227
    • Bolger, A.P.1
  • 7
    • 37849053243 scopus 로고    scopus 로고
    • Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: Observer-blinded trial
    • Okonko DO et al (2008) Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: observer-blinded trial. J Am Coll Cardiol 51:103-112
    • (2008) J Am Coll Cardiol , vol.51 , pp. 103-112
    • Okonko, D.O.1
  • 8
    • 35248870765 scopus 로고    scopus 로고
    • Intravenous iron reduces NTpro- brain natriuretic peptide in anemic patients with chronic heart failure and renal insufficiency
    • Toblli JE et al (2007) Intravenous iron reduces NTpro- brain natriuretic peptide in anemic patients with chronic heart failure and renal insufficiency. J Am Coll Cardiol 50:1657-1665
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1657-1665
    • Toblli, J.E.1
  • 9
    • 50049102529 scopus 로고    scopus 로고
    • Intravenous iron without erythropoietin for the treatment of iron deficiency anemia in patients with moderate to severe congestive heart failure and chronic kidney insufficiency
    • Usmanov RI et al (2008) Intravenous iron without erythropoietin for the treatment of iron deficiency anemia in patients with moderate to severe congestive heart failure and chronic kidney insufficiency. J Nephrol 21:236-242
    • (2008) J Nephrol , vol.21 , pp. 236-242
    • Usmanov, R.I.1
  • 10
    • 72449156527 scopus 로고    scopus 로고
    • Ferric carboxymaltose in patients with heart failure and iron deficiency
    • Anker SD et al (2009) Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med 361 (25): 2436-2448
    • (2009) N Engl J Med , vol.361 , Issue.25 , pp. 2436-2448
    • Anker, S.D.1
  • 11
    • 84982252317 scopus 로고    scopus 로고
    • Anemia and erythropoietin in heart failure
    • van der Meer P et al (2008) Anemia and erythropoietin in heart failure. Heart Fail Monit 6 (1):28-33
    • (2008) Heart Fail Monit , vol.6 , Issue.1 , pp. 28-33
    • Van Der Meer, P.1
  • 12
    • 43749089210 scopus 로고    scopus 로고
    • Anemia and chronic heart failure implications and treatment options
    • Anand IS (2008) Anemia and chronic heart failure implications and treatment options. J Am Coll Cardiol 52 (7):501-511
    • (2008) J Am Coll Cardiol , vol.52 , Issue.7 , pp. 501-511
    • Anand, I.S.1
  • 13
    • 0031821059 scopus 로고    scopus 로고
    • Proinflammatory cytokines lowering erythropoietin production
    • Jelkmann W (1998) Proinflammatory cytokines lowering erythropoietin production. J Interferon Cytokine Res 18 (8): 555-559
    • (1998) J Interferon Cytokine Res , vol.18 , Issue.8 , pp. 555-559
    • Jelkmann, W.1
  • 14
    • 14744278436 scopus 로고    scopus 로고
    • Anemia of chronic disease
    • Weiss G, Goodnough LT (2005) Anemia of chronic disease. N Engl J Med 352 (10):1011-1023
    • (2005) N Engl J Med , vol.352 , Issue.10 , pp. 1011-1023
    • Weiss, G.1    Goodnough, L.T.2
  • 15
    • 21744442256 scopus 로고    scopus 로고
    • Circulating erythropoietin levels and prognosis in patients with congestive heart failure: Comparison with neurohormonal and inflammatory markers
    • George J et al (2005) Circulating erythropoietin levels and prognosis in patients with congestive heart failure: comparison with neurohormonal and inflammatory markers. Arch Intern Med 165 (11):1304-1309
    • (2005) Arch Intern Med , vol.165 , Issue.11 , pp. 1304-1309
    • George, J.1
  • 16
    • 45849129725 scopus 로고    scopus 로고
    • Adequacy of endogenous erythropoietin levels and mortality in anaemic heart failure patients
    • van der Meer P et al (2008) Adequacy of endogenous erythropoietin levels and mortality in anaemic heart failure patients. Eur Heart J 29 (12):1510-1515
    • (2008) Eur Heart J , vol.29 , Issue.12 , pp. 1510-1515
    • Van Der Meer, P.1
  • 17
    • 74949094517 scopus 로고    scopus 로고
    • Endogenous erythropoietin and outcome in heart failure
    • Belonje AM et al (2010) Endogenous erythropoietin and outcome in heart failure. Circulation 121 (2):245-251
    • (2010) Circulation , vol.121 , Issue.2 , pp. 245-251
    • Belonje, A.M.1
  • 18
    • 77954932493 scopus 로고    scopus 로고
    • Bone marrow dysfunction in chronic heart failure patients
    • Westenbrink BD et al (2010) Bone marrow dysfunction in chronic heart failure patients. Eur J Heart Fail 12 (7):676-684
    • (2010) Eur J Heart Fail , vol.12 , Issue.7 , pp. 676-684
    • Westenbrink, B.D.1
  • 19
    • 34548044947 scopus 로고    scopus 로고
    • Preconditioning and postconditioning: United at reperfusion
    • Hausenloy DJ, Yellon DM (2007) Preconditioning and postconditioning: United at reperfusion. Pharmacol Ther 116 (2): 173-191
    • (2007) Pharmacol Ther , vol.116 , Issue.2 , pp. 173-191
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 20
    • 66749173169 scopus 로고    scopus 로고
    • Molecular basis of cardioprotection by erythropoietin
    • Burger D, Xenocostas A, Feng QP (2009) Molecular basis of cardioprotection by erythropoietin. Curr Mol Pharmacol 2 (1): 56-69
    • (2009) Curr Mol Pharmacol , vol.2 , Issue.1 , pp. 56-69
    • Burger, D.1    Xenocostas, A.2    Feng, Q.P.3
  • 21
    • 47649106855 scopus 로고    scopus 로고
    • Activation of endothelial nitric oxide synthase is critical for erythropoietin-induced mobilization of progenitor cells
    • Santhanam AV et al (2008) Activation of endothelial nitric oxide synthase is critical for erythropoietin-induced mobilization of progenitor cells. Peptides 29 (8):1451-1455
    • (2008) Peptides , vol.29 , Issue.8 , pp. 1451-1455
    • Santhanam, A.V.1
  • 22
    • 0345276632 scopus 로고    scopus 로고
    • Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
    • Aicher A et al (2003) Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nature Med 9 (11):1370-1376
    • (2003) Nature Med , vol.9 , Issue.11 , pp. 1370-1376
    • Aicher, A.1
  • 23
    • 77955136355 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is crucial for erythropoietin-induced improvement of cardiac function in heart failure
    • Westenbrink BD et al (2010) Vascular endothelial growth factor is crucial for erythropoietin-induced improvement of cardiac function in heart failure. Cardiovasc Res 87 (1):30-39
    • (2010) Cardiovasc Res , vol.87 , Issue.1 , pp. 30-39
    • Westenbrink, B.D.1
  • 24
    • 43049090142 scopus 로고    scopus 로고
    • Erythropoietin in cardiac disease: New features of an old drug
    • Ruifrok WP et al (2008) Erythropoietin in cardiac disease: new features of an old drug. Eur J Pharmacol 585 (2-3):270-277
    • (2008) Eur J Pharmacol , vol.585 , Issue.2-3 , pp. 270-277
    • Ruifrok, W.P.1
  • 25
    • 33745395054 scopus 로고    scopus 로고
    • Erythropoietin-mobilized endothelial progenitors enhance reendothelialization via Akt-endothelial nitric oxide synthase activation and prevent neointimal hyperplasia
    • Urao N et al (2006) Erythropoietin-mobilized endothelial progenitors enhance reendothelialization via Akt-endothelial nitric oxide synthase activation and prevent neointimal hyperplasia. Circ Res 98 (11):1405-1413
    • (2006) Circ Res , vol.98 , Issue.11 , pp. 1405-1413
    • Urao, N.1
  • 26
    • 0042738942 scopus 로고    scopus 로고
    • Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization
    • Heeschen C et al (2003) Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization. Blood 102 (4):1340-1346
    • (2003) Blood , vol.102 , Issue.4 , pp. 1340-1346
    • Heeschen, C.1
  • 27
    • 0038163900 scopus 로고    scopus 로고
    • Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury
    • Cai Z et al (2003) Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury. Circulation 108 (1):79-85
    • (2003) Circulation , vol.108 , Issue.1 , pp. 79-85
    • Cai, Z.1
  • 28
    • 0141593556 scopus 로고    scopus 로고
    • Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats
    • Moon C et al (2003) Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats. Proc Natl Acad Sci U S A 100 (20):11612-11617
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.20 , pp. 11612-11617
    • Moon, C.1
  • 29
    • 64749104944 scopus 로고    scopus 로고
    • Erythropoietin protects from reperfusioninduced myocardial injury by enhancing coronary endothelial nitric oxide production
    • Mihov D et al. (2009) Erythropoietin protects from reperfusioninduced myocardial injury by enhancing coronary endothelial nitric oxide production. Eur J Cardiothorac Surg 35 (5): 839-46; discussion 846
    • (2009) Eur J Cardiothorac Surg , vol.35 , pp. 5
    • Mihov, D.1
  • 30
    • 21344459065 scopus 로고    scopus 로고
    • Erythropoietin induces neovascularization and improves cardiac function in rats with heart failure after myocardial infarction
    • van der Meer P et al (2005) Erythropoietin induces neovascularization and improves cardiac function in rats with heart failure after myocardial infarction. J Am Coll Cardiol 46 (1):125-133
    • (2005) J Am Coll Cardiol , vol.46 , Issue.1 , pp. 125-133
    • Van Der Meer, P.1
  • 31
    • 33745250458 scopus 로고    scopus 로고
    • Erythropoietin enhances neovascularization of ischemic myocardium and improves left ventricular dysfunction after myocardial infarction in dogs
    • Hirata A et al (2006) Erythropoietin enhances neovascularization of ischemic myocardium and improves left ventricular dysfunction after myocardial infarction in dogs. J Am Coll Cardiol 48 (1):176-184
    • (2006) J Am Coll Cardiol , vol.48 , Issue.1 , pp. 176-184
    • Hirata, A.1
  • 32
    • 33846188979 scopus 로고    scopus 로고
    • Delayed erythropoietin therapy reduces post-MI cardiac remodeling only at a dose that mobilizes endothelial progenitor cells
    • Prunier F et al (2007) Delayed erythropoietin therapy reduces post-MI cardiac remodeling only at a dose that mobilizes endothelial progenitor cells. Am J Physiol Heart Circ Physiol 292 (1): H522-H529
    • (2007) Am J Physiol Heart Circ Physiol , vol.292 , Issue.1
    • Prunier, F.1
  • 33
    • 33644871048 scopus 로고    scopus 로고
    • Preventive effect of erythropoietin on cardiac dysfunction in doxorubicin-induced cardiomyopathy
    • Li L et al (2006) Preventive effect of erythropoietin on cardiac dysfunction in doxorubicin-induced cardiomyopathy. Circulation 113 (4):535-543
    • (2006) Circulation , vol.113 , Issue.4 , pp. 535-543
    • Li, L.1
  • 34
    • 85047691007 scopus 로고    scopus 로고
    • A novel protective effect of erythropoietin in the infarcted heart
    • Parsa CJ et al (2003) A novel protective effect of erythropoietin in the infarcted heart. J Clin Invest 112 (7):999-1007
    • (2003) J Clin Invest , vol.112 , Issue.7 , pp. 999-1007
    • Parsa, C.J.1
  • 35
    • 0142187248 scopus 로고    scopus 로고
    • Endothelial progenitor cell proliferation and differentiation is regulated by erythropoietin
    • Bahlmann FH et al (2003) Endothelial progenitor cell proliferation and differentiation is regulated by erythropoietin. Kidney Int 64 (5):1648-1652
    • (2003) Kidney Int , vol.64 , Issue.5 , pp. 1648-1652
    • Bahlmann, F.H.1
  • 36
    • 34547788774 scopus 로고    scopus 로고
    • Early haemoglobin-independent increase of plasma erythropoietin levels in patients with acute myocardial infarction
    • Ferrario M et al (2007) Early haemoglobin-independent increase of plasma erythropoietin levels in patients with acute myocardial infarction. Eur Heart J 28 (15):1805-1813
    • (2007) Eur Heart J , vol.28 , Issue.15 , pp. 1805-1813
    • Ferrario, M.1
  • 37
    • 20944439418 scopus 로고    scopus 로고
    • High serum erythropoietin level is associated with smaller infarct size in patients with acute myocardial infarction who undergo successful primary percutaneous coronary intervention
    • Namiuchi S et al (2005) High serum erythropoietin level is associated with smaller infarct size in patients with acute myocardial infarction who undergo successful primary percutaneous coronary intervention. J Am Coll Cardiol 45 (9):1406-1412
    • (2005) J Am Coll Cardiol , vol.45 , Issue.9 , pp. 1406-1412
    • Namiuchi, S.1
  • 38
    • 33745025709 scopus 로고    scopus 로고
    • A single bolus of a long-acting erythropoietin analogue darbepoetin alfa in patients with acute myocardial infarction: A randomized feasibility and safety study
    • Lipsic E et al (2006) A single bolus of a long-acting erythropoietin analogue darbepoetin alfa in patients with acute myocardial infarction: a randomized feasibility and safety study. Cardiovasc Drugs Ther 20 (2):135-141
    • (2006) Cardiovasc Drugs Ther , vol.20 , Issue.2 , pp. 135-141
    • Lipsic, E.1
  • 39
    • 79957445321 scopus 로고    scopus 로고
    • The effect of intravenous administration of erythropoietin on the infarct size in primary percutaneous coronary intervention
    • Suh JW et al (2011) The effect of intravenous administration of erythropoietin on the infarct size in primary percutaneous coronary intervention. Int J Cardiol 149 (2):216-220
    • (2011) Int J Cardiol , vol.149 , Issue.2 , pp. 216-220
    • Suh, J.W.1
  • 40
    • 77958518157 scopus 로고    scopus 로고
    • A single dose of erythropoietin in STelevation myocardial infarction
    • Voors AA et al (2010) A single dose of erythropoietin in STelevation myocardial infarction. Eur Heart J 31 (21):2593-2600
    • (2010) Eur Heart J , vol.31 , Issue.21 , pp. 2593-2600
    • Voors, A.A.1
  • 41
    • 79951722690 scopus 로고    scopus 로고
    • High-dose erythropoietin in patients with acute myocardial infarction: A pilot, randomised, placebo-controlled study
    • Epub 2009 Nov 10
    • Ferrario M et al (2011) High-dose erythropoietin in patients with acute myocardial infarction: A pilot, randomised, placebo-controlled study. Int J Cardiol 147 (1):124-131 Epub 2009 Nov 10
    • (2011) Int J Cardiol , vol.147 , Issue.1 , pp. 124-131
    • Ferrario, M.1
  • 42
    • 0036436322 scopus 로고    scopus 로고
    • Randomized trial of darbepoetin alfa for treatment of renal anemia at a reduced dose frequency compared with rHuEPO in dialysis patients
    • Vanrenterghem Y et al (2002) Randomized trial of darbepoetin alfa for treatment of renal anemia at a reduced dose frequency compared with rHuEPO in dialysis patients. Kidney Int 62:2167-2175
    • (2002) Kidney Int , vol.62 , pp. 2167-2175
    • Vanrenterghem, Y.1
  • 43
    • 0035370037 scopus 로고    scopus 로고
    • The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: A randomized controlled study
    • Silverberg DS et al (2001) The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: a randomized controlled study. J Am Coll Cardiol 37 (7):1775-1780
    • (2001) J Am Coll Cardiol , vol.37 , Issue.7 , pp. 1775-1780
    • Silverberg, D.S.1
  • 44
    • 0037458127 scopus 로고    scopus 로고
    • Effect of erythropoietin on exercise capacity in patients with moderate to severe chronic heart failure
    • Mancini DM et al (2003) Effect of erythropoietin on exercise capacity in patients with moderate to severe chronic heart failure. Circulation 107 (2):294-299
    • (2003) Circulation , vol.107 , Issue.2 , pp. 294-299
    • Mancini, D.M.1
  • 45
    • 33845216454 scopus 로고    scopus 로고
    • Erythropoietin improves anemia exercise tolerance and renal function and reduces B-type natriuretic peptide and hospitalization in patients with heart failure and anemia
    • Palazzuoli A et al (2006) Erythropoietin improves anemia exercise tolerance and renal function and reduces B-type natriuretic peptide and hospitalization in patients with heart failure and anemia. Am Heart J 152 (6):1096e9-1096e15
    • (2006) Am Heart J , vol.152 , Issue.6 , pp. 10969-109615
    • Palazzuoli, A.1
  • 46
    • 33846936320 scopus 로고    scopus 로고
    • Effect of darbepoetin alfa on exercise tolerance in anemic patients with symptomatic chronic heart failure: A randomized, double-blind, placebo-controlled trial
    • Ponikowski P et al (2007) Effect of darbepoetin alfa on exercise tolerance in anemic patients with symptomatic chronic heart failure: a randomized, double-blind, placebo-controlled trial. J Am Coll Cardiol 49 (7):753-762
    • (2007) J Am Coll Cardiol , vol.49 , Issue.7 , pp. 753-762
    • Ponikowski, P.1
  • 47
    • 34548798205 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo- controlled study to evaluate the effect of two dosing regimens of darbepoetin alfa in patients with heart failure and anaemia
    • van Veldhuisen DJ et al (2007) Randomized, double-blind, placebo- controlled study to evaluate the effect of two dosing regimens of darbepoetin alfa in patients with heart failure and anaemia. Eur Heart J 28 (18):2208-2216
    • (2007) Eur Heart J , vol.28 , Issue.18 , pp. 2208-2216
    • Van Veldhuisen, D.J.1
  • 48
    • 41049115024 scopus 로고    scopus 로고
    • Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemia
    • Ghali JK et al (2008) Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemia. Circulation 117 (4):526-535
    • (2008) Circulation , vol.117 , Issue.4 , pp. 526-535
    • Ghali, J.K.1
  • 49
    • 40849133773 scopus 로고    scopus 로고
    • Effects of darbepoetin alpha on right and left ventricular systolic and diastolic function in anemic patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    • Parissis JT et al (2008) Effects of darbepoetin alpha on right and left ventricular systolic and diastolic function in anemic patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am Heart J 155 (4):751e1-751e7
    • (2008) Am Heart J , vol.155 , Issue.4 , pp. 7511-7517
    • Parissis, J.T.1
  • 50
    • 68249099779 scopus 로고    scopus 로고
    • Beta-erythropoietin effects on ventricular remodeling, left and right systolic function, pulmonary pressure, and hospitalizations in patients affected with heart failure and anemia
    • Palazzuoli A et al (2009) Beta-erythropoietin effects on ventricular remodeling, left and right systolic function, pulmonary pressure, and hospitalizations in patients affected with heart failure and anemia. J Cardiovasc Pharmacol 53 (6):462-467
    • (2009) J Cardiovasc Pharmacol , vol.53 , Issue.6 , pp. 462-467
    • Palazzuoli, A.1
  • 51
    • 63749084132 scopus 로고    scopus 로고
    • Effects of Darbepoetin Alfa on plasma mediators of oxidative and nitrosative stress in anemic patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    • Parissis JT et al (2009) Effects of Darbepoetin Alfa on plasma mediators of oxidative and nitrosative stress in anemic patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol 103 (8):1134-1138
    • (2009) Am J Cardiol , vol.103 , Issue.8 , pp. 1134-1138
    • Parissis, J.T.1
  • 52
    • 74449083654 scopus 로고    scopus 로고
    • Effects of erythropoietin administration on mitral regurgitation and left ventricular remodeling in heart failure patients
    • Cosyns B et al (2010) Effects of erythropoietin administration on mitral regurgitation and left ventricular remodeling in heart failure patients. Int J Cardiol 138 (3):306-307
    • (2010) Int J Cardiol , vol.138 , Issue.3 , pp. 306-307
    • Cosyns, B.1
  • 53
    • 79951950401 scopus 로고    scopus 로고
    • Anemia correction by erythropoietin reduces BNP levels, hospitalization rate, and NYHA class in patients with cardio-renal anemia syndrome
    • Epub 2010 May 29
    • Palazzuoli A et al (2011) Anemia correction by erythropoietin reduces BNP levels, hospitalization rate, and NYHA class in patients with cardio-renal anemia syndrome. Clin Exp Med 11 (1):43-48 Epub 2010 May 29
    • (2011) Clin Exp Med , vol.11 , Issue.1 , pp. 43-48
    • Palazzuoli, A.1
  • 54
    • 67650766504 scopus 로고    scopus 로고
    • Erythropoietin treatment in patients with chronic heart failure: A meta-analysis
    • van der Meer P et al (2009) Erythropoietin treatment in patients with chronic heart failure: a meta-analysis. Heart 95 (16): 1309-1314
    • (2009) Heart , vol.95 , Issue.16 , pp. 1309-1314
    • Van Der Meer, P.1
  • 55
    • 0032572913 scopus 로고    scopus 로고
    • The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin
    • Besarab A et al (1998) The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin. N Engl J Med 339 (9): 584-590
    • (1998) N Engl J Med , vol.339 , Issue.9 , pp. 584-590
    • Besarab, A.1
  • 56
    • 33750983605 scopus 로고    scopus 로고
    • Correction of anemia with epoetin alfa in chronic kidney disease
    • Singh AK et al (2006) Correction of anemia with epoetin alfa in chronic kidney disease. N Engl J Med 355 (20):2085-2098
    • (2006) N Engl J Med , vol.355 , Issue.20 , pp. 2085-2098
    • Singh, A.K.1
  • 57
    • 70949108082 scopus 로고    scopus 로고
    • A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease
    • Pfeffer MA et al (2009) A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease. N Engl J Med 361 (21): 2019-2032
    • (2009) N Engl J Med , vol.361 , Issue.21 , pp. 2019-2032
    • Pfeffer, M.A.1
  • 58
    • 74849088872 scopus 로고    scopus 로고
    • Erythropoiesis-stimulating agents-time for a re-evaluation
    • Unger EF et al (2010) Erythropoiesis-stimulating agents-time for a re-evaluation. N Engl J Med 362 (3):189-192
    • (2010) N Engl J Med , vol.362 , Issue.3 , pp. 189-192
    • Unger, E.F.1
  • 59
    • 77956704796 scopus 로고    scopus 로고
    • Erythropoietic response and outcomes in kidney disease and type 2 diabetes
    • Solomon SD et al (2010) Erythropoietic response and outcomes in kidney disease and type 2 diabetes. N Engl J Med 363 (12): 1146-1155
    • (2010) N Engl J Med , vol.363 , Issue.12 , pp. 1146-1155
    • Solomon, S.D.1
  • 60
    • 0041976976 scopus 로고    scopus 로고
    • Breast cancer trial with erythropoietin terminated unexpectedly
    • Leyland-Jones B (2003) Breast cancer trial with erythropoietin terminated unexpectedly. Lancet Oncol 4 (8):459-460
    • (2003) Lancet Oncol , vol.4 , Issue.8 , pp. 459-460
    • Leyland-Jones, B.1
  • 61
    • 70949095435 scopus 로고    scopus 로고
    • Recombinant human erythropoietin in the treatment of acute ischemic stroke
    • Ehrenreich H et al (2009) Recombinant human erythropoietin in the treatment of acute ischemic stroke. Stroke 40 (12):e647-e656
    • (2009) Stroke , vol.40 , Issue.12
    • Ehrenreich, H.1
  • 62
    • 77955463731 scopus 로고    scopus 로고
    • Erythropoietin treatment in patients with combined heart and renal failure: Objectives and design of the EPOCARES study
    • van der Putten K et al (2010) Erythropoietin treatment in patients with combined heart and renal failure: objectives and design of the EPOCARES study. J Nephrol. 23 (4):363-368
    • (2010) J Nephrol , vol.23 , Issue.4 , pp. 363-368
    • Van Der Putten, K.1
  • 63
    • 67749103752 scopus 로고    scopus 로고
    • Design of the Reduction of Events with Darbepoetin alfa in Heart Failure (RED-HF): A Phase III, anaemia correction, morbidity-mortality trial
    • McMurray JJ et al (2009) Design of the Reduction of Events with Darbepoetin alfa in Heart Failure (RED-HF): a Phase III, anaemia correction, morbidity-mortality trial. Eur J Heart Fail 11 (8): 795-801
    • (2009) Eur J Heart Fail , vol.11 , Issue.8 , pp. 795-801
    • McMurray, J.J.1
  • 64
    • 37549020370 scopus 로고    scopus 로고
    • Low-dose erythropoietin improves cardiac function in experimental heart failure without increasing haematocrit
    • Lipsic E et al (2008) Low-dose erythropoietin improves cardiac function in experimental heart failure without increasing haematocrit. Eur J Heart Fail 10 (1):22-29
    • (2008) Eur J Heart Fail , vol.10 , Issue.1 , pp. 22-29
    • Lipsic, E.1
  • 65
    • 13844320400 scopus 로고    scopus 로고
    • A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury
    • Fiordaliso F et al (2005) A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury. Proc Natl Acad Sci U S A 102 (6):2046-2051
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.6 , pp. 2046-2051
    • Fiordaliso, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.