Cardioprotection-time to take into account clinical complexity: The case of Antiplatelet agents: Editorial to two classes of anti-platelet drugs reduce anatomical infarct size in monkey hearts by xi-Ming yang et al.

Cardiovascular Drugs and Therapy

Volumn 27, Issue 2, 2013, Pages 105-107

  Roubille, François ^a,b,c   Tardif, Jean Claude ^b  

^a MONTREAL HEART INSTITUTE   (Canada)

^b UNIV MONTPELLIER   (France)

^c MONTPELLIER UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBOCYTIC AGENT; CANGRELOR; CLOPIDOGREL;

CARDIOVASCULAR EFFECT; DRUG EFFECT; HEART INFARCTION; HEART PROTECTION; HUMAN; ISCHEMIC POSTCONDITIONING; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; REVIEW; TREATMENT OUTCOME;

ADENOSINE MONOPHOSPHATE; ANIMALS; ANTIBODIES; MALE; MYOCARDIAL INFARCTION; PLATELET AGGREGATION INHIBITORS; PLATELET MEMBRANE GLYCOPROTEINS; PURINERGIC P2Y RECEPTOR ANTAGONISTS;

EID: 84878284743     PISSN: 09203206     EISSN: 15737241     Source Type: Journal    
DOI: 10.1007/s10557-013-6443-3     Document Type: Review

References (21)

1. WHO. WHO Fact sheet N°310, updated June 2011.2011.
2. Taylor J. 2012 ESC Guidelines on acute myocardial infarction (STEMI). Eur Heart J. 2012;33:2501-2.
3. Antman EM, Anbe DT, Armstrong PW, et al. ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of Patients with Acute Myocardial Infarction). Circulation. 2004;110:e82-292.
4. Yellon DM, Hausenloy DJ. Myocardial reperfusion injury. New Engl J Med. 2007;357:1121-35.
5. Zhao ZQ, Corvera JS, Halkos ME, et al. Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. Am J Physiol Heart Circ Physiol. 2003;285:H579-88.
6. Roubille F, Franck-Miclo A, Covinhes A, et al. Delayed postconditioning in the mouse heart in vivo. Circulation. 2011;124:1330-6.
7. Paillard M, Gomez L, Augeul L, Loufouat J, Lesnefsky EJ, Ovize M. Postconditioning inhibits mPTP opening independent of oxidative phosphorylation and membrane potential. J Mol Cell Cardiol. 2009;46:902-9.
8. Roubille F, Combes S, Leal-Sanchez J, et al. Myocardial expression of a dominant-negative form of Daxx decreases infarct size and attenuates apoptosis in an in vivo mouse model of ischemia/ reperfusion injury. Circulation. 2007;116:2709-17.
9. Vincent A, Gahide G, Sportouch-Dukhan C, et al. Downregulation of the transcription factor ZAC1 upon pre- and postconditioning protects against I/R injury in the mouse myocardium. Cardiovasc Res. 2012;94:351-8.
10. Piot C, Croisille P, Staat P, et al. Effect of cyclosporine on reperfusion injury in acute myocardial infarction. New Engl J Med. 2008;359:473-81.
11. Staat P, Rioufol G, Piot C, et al. Postconditioning the human heart. Circulation. 2005;112:2143-8.
12. Thibault H, Piot C, Staat P, et al. Long-Term benefit of postconditioning. Circulation. 2008;117:1037-44.
13. Thuny F, Lairez O, Roubille F, et al. Post-conditioning reduces infarct size and edema in patients with ST-segment elevation myocardial infarction. J Am Coll Cardiol. 2012;59:2175-81.
14. Yang X-M, Liu Y, Cui L, et al. Platelet P2Y12 blockers confer direct postconditioning-like protection in reperfused rabbit hearts. J Cardiovasc Pharmacol Ther 2013.
15. Yang XM, Liu Y, Cui L, et al. Two classes of anti-platelet drugs reduce anatomical infarct size in monkey hearts. Cardiovas Drugs Ther 2013;27: this issue
16. Xu Y, Huo Y, Toufektsian MC, et al. Activated platelets contribute importantly to myocardial reperfusion injury. Am J Physiol Heart Circ Physiol. 2006;290:H692-9.
17. Schonberger T, Ziegler M, Borst O, et al. The dimeric platelet collagen receptor GPVI-Fc reduces platelet adhesion to activated endothelium and preserves myocardial function after transient ischemia in mice. Am J Physiol Cell Physiol. 2012;303:C757-66.
18. Diehl P, Olivier C, Halscheid C, Helbing T, Bode C, Moser M. Clopidogrel affects leukocyte dependent platelet aggregation by P2Y12 expressing leukocytes. Basic Res Cardiol. 2010;105:379- 87.
19. Krijnen PAJ, Hahn NE, Kholova I, et al. Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients. Basic Res Cardiol. 2012;107:233.
20. Montoro-Garcia S, Shantsila E, Marin F, Blann A, Lip GY. Circulating microparticles: new insights into the biochemical basis of microparticle release and activity. Basic Res Cardiol. 2011;106:911-23.
21. Roubille F, Lairez O, Mewton N, et al. Cardioprotection by clopidogrel in acute ST-elevated myocardial infarction patients: A retrospective analysis. Basic Res Cardiol. 2012;107:275.